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M K Gately
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Journal Articles

Characterization of IL-12 receptor beta1 chain (IL-12Rbeta1)-deficient mice: IL-12Rbeta1 is an essential component of the functional mouse IL-12 receptor.

C Wu, J Ferrante, M K Gately, J Magram
Journal: The Journal of Immunology
J Immunol (1997) 159 (4): 1658–1665.
DOI: https://doi.org/10.4049/jimmunol.159.4.1658
Published: 15 August 1997
View article titled, Characterization of IL-12 receptor beta1 chain (IL-12Rbeta1)-deficient mice: IL-12Rbeta1 is an essential component of the functional mouse IL-12 receptor.
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Journal Articles

IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporidium parvum.

J F Urban, Jr, R Fayer, S J Chen, W C Gause, M K Gately, F D Finkelman
Journal: The Journal of Immunology
J Immunol (1996) 156 (1): 263–268.
DOI: https://doi.org/10.4049/jimmunol.156.1.263
Published: 01 January 1996
View article titled, IL-12 protects immunocompetent and immunodeficient neonatal mice against infection with Cryptosporidium parvum.
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Journal Articles

Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity.

P Ling, M K Gately, U Gubler, A S Stern, P Lin, K Hollfelder, C Su, Y C Pan, J Hakimi
Journal: The Journal of Immunology
J Immunol (1995) 154 (1): 116–127.
DOI: https://doi.org/10.4049/jimmunol.154.1.116
Published: 01 January 1995
View article titled, Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity.
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Journal Articles

In vitro maturation of neonatal human CD8 T lymphocytes into IL-4- and IL-5-producing cells.

D G Byun, C E Demeure, L P Yang, U Shu, H Ishihara, N Vezzio, M K Gately, G Delespesse
Journal: The Journal of Immunology
J Immunol (1994) 153 (11): 4862–4871.
DOI: https://doi.org/10.4049/jimmunol.153.11.4862
Published: 01 December 1994
View article titled, In vitro maturation of neonatal human CD8 T lymphocytes into IL-4- and IL-5-producing cells.
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Journal Articles

IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would develop chronic, autoimmune graft-versus-host disease.

C S Via, V Rus, M K Gately, F D Finkelman
Journal: The Journal of Immunology
J Immunol (1994) 153 (9): 4040–4047.
DOI: https://doi.org/10.4049/jimmunol.153.9.4040
Published: 01 November 1994
View article titled, IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would develop chronic, autoimmune graft-versus-host disease.
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Journal Articles

IL-12 regulates T helper type 1 cytokine responses in human infectious disease.

P A Sieling, X H Wang, M K Gately, J L Oliveros, T McHugh, P F Barnes, S F Wolf, L Golkar, M Yamamura, Y Yogi
Journal: The Journal of Immunology
J Immunol (1994) 153 (8): 3639–3647.
DOI: https://doi.org/10.4049/jimmunol.153.8.3639
Published: 15 October 1994
View article titled, IL-12 regulates T helper type 1 cytokine responses in human infectious disease.
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Journal Articles

Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production.

C L Nastala, H D Edington, T G McKinney, H Tahara, M A Nalesnik, M J Brunda, M K Gately, S F Wolf, R D Schreiber, W J Storkus
Journal: The Journal of Immunology
J Immunol (1994) 153 (4): 1697–1706.
DOI: https://doi.org/10.4049/jimmunol.153.4.1697
Published: 15 August 1994
View article titled, Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production.
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Journal Articles

Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130.

A O Chua, R Chizzonite, B B Desai, T P Truitt, P Nunes, L J Minetti, R R Warrier, D H Presky, J F Levine, M K Gately
Journal: The Journal of Immunology
J Immunol (1994) 153 (1): 128–136.
DOI: https://doi.org/10.4049/jimmunol.153.1.128
Published: 01 July 1994
View article titled, Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130.
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Journal Articles

IL-12 influences intrathymic T cell development.

D I Godfrey, J Kennedy, M K Gately, J Hakimi, B R Hubbard, A Zlotnik
Journal: The Journal of Immunology
J Immunol (1994) 152 (6): 2729–2735.
DOI: https://doi.org/10.4049/jimmunol.152.6.2729
Published: 15 March 1994
View article titled, IL-12 influences intrathymic T cell development.
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Journal Articles

Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma.

C S Tripp, M K Gately, J Hakimi, P Ling, E R Unanue
Journal: The Journal of Immunology
J Immunol (1994) 152 (4): 1883–1887.
DOI: https://doi.org/10.4049/jimmunol.152.4.1883
Published: 15 February 1994
View article titled, Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma.
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Journal Articles

Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection.

S C Morris, K B Madden, J J Adamovicz, W C Gause, B R Hubbard, M K Gately, F D Finkelman
Journal: The Journal of Immunology
J Immunol (1994) 152 (3): 1047–1056.
DOI: https://doi.org/10.4049/jimmunol.152.3.1047
Published: 01 February 1994
View article titled, Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection.
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Journal Articles

Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC.

J Hakimi, V C Ha, P Lin, E Campbell, M K Gately, M Tsudo, P W Payne, T A Waldmann, A J Grant, W H Tsien
Journal: The Journal of Immunology
J Immunol (1993) 151 (2): 1075–1085.
DOI: https://doi.org/10.4049/jimmunol.151.2.1075
Published: 15 July 1993
View article titled, Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC.
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Journal Articles

Cloning and expression of murine IL-12.

D S Schoenhaut, A O Chua, A G Wolitzky, P M Quinn, C M Dwyer, W McComas, P C Familletti, M K Gately, U Gubler
Journal: The Journal of Immunology
J Immunol (1992) 148 (11): 3433–3440.
DOI: https://doi.org/10.4049/jimmunol.148.11.3433
Published: 01 June 1992
View article titled, Cloning and expression of murine IL-12.
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Journal Articles

IL-12 receptor. II. Distribution and regulation of receptor expression.

B B Desai, P M Quinn, A G Wolitzky, P K Mongini, R Chizzonite, M K Gately
Journal: The Journal of Immunology
J Immunol (1992) 148 (10): 3125–3132.
DOI: https://doi.org/10.4049/jimmunol.148.10.3125
Published: 15 May 1992
View article titled, IL-12 receptor. II. Distribution and regulation of receptor expression.
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Journal Articles

IL-12 receptor. I. Characterization of the receptor on phytohemagglutinin-activated human lymphoblasts.

R Chizzonite, T Truitt, B B Desai, P Nunes, F J Podlaski, A S Stern, M K Gately
Journal: The Journal of Immunology
J Immunol (1992) 148 (10): 3117–3124.
DOI: https://doi.org/10.4049/jimmunol.148.10.3117
Published: 15 May 1992
View article titled, IL-12 receptor. I. Characterization of the receptor on phytohemagglutinin-activated human lymphoblasts.
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Journal Articles

IL-12: monoclonal antibodies specific for the 40-kDa subunit block receptor binding and biologic activity on activated human lymphoblasts.

R Chizzonite, T Truitt, F J Podlaski, A G Wolitzky, P M Quinn, P Nunes, A S Stern, M K Gately
Journal: The Journal of Immunology
J Immunol (1991) 147 (5): 1548–1556.
DOI: https://doi.org/10.4049/jimmunol.147.5.1548
Published: 01 September 1991
View article titled, IL-12: monoclonal antibodies specific for the 40-kDa subunit block receptor binding and biologic activity on activated human lymphoblasts.
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Journal Articles

Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor).

M K Gately, B B Desai, A G Wolitzky, P M Quinn, C M Dwyer, F J Podlaski, P C Familletti, F Sinigaglia, R Chizonnite, U Gubler
Journal: The Journal of Immunology
J Immunol (1991) 147 (3): 874–882.
DOI: https://doi.org/10.4049/jimmunol.147.3.874
Published: 01 August 1991
View article titled, Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor).
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Journal Articles

Role of asialo-GM1-positive lymphoid cells in mediating the toxic effects of recombinant IL-2 in mice.

M K Gately, T D Anderson, T J Hayes
Journal: The Journal of Immunology
J Immunol (1988) 141 (1): 189–200.
DOI: https://doi.org/10.4049/jimmunol.141.1.189
Published: 01 July 1988
View article titled, Role of asialo-GM1-positive lymphoid cells in mediating the toxic effects of recombinant IL-2 in mice.
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Journal Articles

Synergy between recombinant interleukin 2 (rIL 2) and IL 2-depleted lymphokine-containing supernatants in facilitating allogeneic human cytolytic T lymphocyte responses in vitro.

M K Gately, D E Wilson, H L Wong
Journal: The Journal of Immunology
J Immunol (1986) 136 (4): 1274–1282.
DOI: https://doi.org/10.4049/jimmunol.136.4.1274
Published: 15 February 1986
View article titled, Synergy between recombinant interleukin 2 (rIL 2) and IL 2-depleted lymphokine-containing supernatants in facilitating allogeneic human cytolytic T lymphocyte responses in vitro.
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In vitro studies on the cell-mediated immune response to human brain tumors. II. Leukocyte-induced coats of glycosaminoglycan increase the resistance of glioma cells to cellular immune attack.

C L Gately, L M Muul, M A Greenwood, S Papazoglou, S J Dick, P L Kornblith, B H Smith, M K Gately
Journal: The Journal of Immunology
J Immunol (1984) 133 (6): 3387–3395.
DOI: https://doi.org/10.4049/jimmunol.133.6.3387
Published: 01 December 1984
View article titled, In vitro studies on the cell-mediated immune response to human brain tumors. II. Leukocyte-induced coats of glycosaminoglycan increase the resistance of glioma cells to cellular immune attack.
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