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Journal Articles

TLR Activation Pathways in HIV-1–Exposed Seronegative Individuals

Mara Biasin, Luca Piacentini, Sergio Lo Caputo, Valentina Naddeo, Piera Pierotti, Manuela Borelli, Daria Trabattoni, Francesco Mazzotta, Gene M. Shearer, Mario Clerici
Journal: The Journal of Immunology
J Immunol (2010) 184 (5): 2710–2717.
https://doi.org/10.4049/jimmunol.0902463
Published: 01 March 2010
View article titled, TLR Activation Pathways in HIV-1–Exposed Seronegative Individuals
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Includes: Supplementary data
Journal Articles

Combined Effect of Antiretroviral Therapy and Blockade of IDO in SIV-Infected Rhesus Macaques

Adriano Boasso, Monica Vaccari, Dietmar Fuchs, Andrew W. Hardy, Wen-Po Tsai, Elzbieta Tryniszewska, Gene M. Shearer, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2009) 182 (7): 4313–4320.
https://doi.org/10.4049/jimmunol.0803314
Published: 01 April 2009
View article titled, Combined Effect of Antiretroviral Therapy and Blockade of IDO in SIV-Infected Rhesus Macaques
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Includes: Supplementary data
Journal Articles

Immune Activation Driven by CTLA-4 Blockade Augments Viral Replication at Mucosal Sites in Simian Immunodeficiency Virus Infection

Valentina Cecchinato, Elzbieta Tryniszewska, Zhong Min Ma, Monica Vaccari, Adriano Boasso, Wen-Po Tsai, Constantinos Petrovas, Dietmar Fuchs, Jean-Michel Heraud, David Venzon, Gene M. Shearer, Richard A. Koup, Israel Lowy, Christopher J. Miller, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2008) 180 (8): 5439–5447.
https://doi.org/10.4049/jimmunol.180.8.5439
Published: 15 April 2008
View article titled, Immune Activation Driven by CTLA-4 Blockade Augments Viral Replication at Mucosal Sites in Simian Immunodeficiency Virus Infection
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Journal Articles

Interleukin-15 but Not Interleukin-7 Abrogates Vaccine-Induced Decrease in Virus Level in Simian Immunodeficiency Virusmac251-Infected Macaques

Anna Hryniewicz, David A. Price, Marcin Moniuszko, Adriano Boasso, Yvette Edghill-Spano, Sadie M. West, David Venzon, Monica Vaccari, Wen-Po Tsai, Elzbieta Tryniszewska, Janos Nacsa, Francois Villinger, Aftab A. Ansari, Christopher J. Trindade, Michel Morre, David Brooks, Philip Arlen, Helen J. Brown, Christina M. R. Kitchen, Jerome A. Zack, Daniel C. Douek, Gene M. Shearer, Mark G. Lewis, Richard A. Koup, Genoveffa Franchini
Journal: The Journal of Immunology
J Immunol (2007) 178 (6): 3492–3504.
https://doi.org/10.4049/jimmunol.178.6.3492
Published: 15 March 2007
View article titled, Interleukin-15 but Not Interleukin-7 Abrogates Vaccine-Induced Decrease in Virus Level in Simian Immunodeficiency Virus<sub>mac251</sub>-Infected Macaques
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Journal Articles

Cutting Edge: The Prevalence of Regulatory T Cells in Lymphoid Tissue Is Correlated with Viral Load in HIV-Infected Patients

Jan Andersson, Adriano Boasso, Jakob Nilsson, Rui Zhang, Norah J. Shire, Stefan Lindback, Gene M. Shearer, Claire A. Chougnet
Journal: The Journal of Immunology
J Immunol (2005) 174 (6): 3143–3147.
https://doi.org/10.4049/jimmunol.174.6.3143
Published: 15 March 2005
View article titled, Cutting Edge: The Prevalence of Regulatory T Cells in Lymphoid Tissue Is Correlated with Viral Load in HIV-Infected Patients
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Journal Articles

In Vivo CD40-CD154 (CD40 Ligand) Interaction Induces Integrated HIV Expression by APC in an HIV-1-Transgenic Mouse Model

Claire Chougnet, Corona Freitag, Marco Schito, Elaine K. Thomas, Alan Sher, Gene M. Shearer
Journal: The Journal of Immunology
J Immunol (2001) 166 (5): 3210–3217.
https://doi.org/10.4049/jimmunol.166.5.3210
Published: 01 March 2001
View article titled, In Vivo CD40-CD154 (CD40 Ligand) Interaction Induces Integrated HIV Expression by APC in an HIV-1-Transgenic Mouse Model
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Journal Articles

Progression from Acute to Chronic Disease in a Murine Parent-into-F1 Model of Graft-Versus-Host Disease

Jolynne R. Tschetter, Edna Mozes, Gene M. Shearer
Journal: The Journal of Immunology
J Immunol (2000) 165 (10): 5987–5994.
https://doi.org/10.4049/jimmunol.165.10.5987
Published: 15 November 2000
View article titled, Progression from Acute to Chronic Disease in a Murine Parent-into-F<sub>1</sub> Model of Graft-Versus-Host Disease
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Journal Articles

Infection of HIV-1 Transgenic Mice with Mycobacterium avium Induces the Expression of Infectious Virus Selectively from a Mac-1-Positive Host Cell Population

T. Mark Doherty, Claire Chougnet, Marco Schito, Bruce K. Patterson, Cecil Fox, Gene M. Shearer, George Englund, Alan Sher
Journal: The Journal of Immunology
J Immunol (1999) 163 (3): 1506–1515.
https://doi.org/10.4049/jimmunol.163.3.1506
Published: 01 August 1999
View article titled, Infection of HIV-1 Transgenic Mice with <em>Mycobacterium avium</em> Induces the Expression of Infectious Virus Selectively from a Mac-1-Positive Host Cell Population
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Journal Articles

Normal Immune Function of Monocyte-Derived Dendritic Cells from HIV-Infected Individuals: Implications for Immunotherapy

Claire Chougnet, Sandra S. Cohen, Tatsuyoshi Kawamura, Alan L. Landay, Harold A. Kessler, Elaine Thomas, Andrew Blauvelt, Gene M. Shearer
Journal: The Journal of Immunology
J Immunol (1999) 163 (3): 1666–1673.
https://doi.org/10.4049/jimmunol.163.3.1666
Published: 01 August 1999
View article titled, Normal Immune Function of Monocyte-Derived Dendritic Cells from HIV-Infected Individuals: Implications for Immunotherapy
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Journal Articles

Human Glioma-Induced Immunosuppression Involves Soluble Factor(s) That Alters Monocyte Cytokine Profile and Surface Markers

Jian-Ping Zou, Lorri A. Morford, Claire Chougnet, Amy R. Dix, Andrew G. Brooks, Naomi Torres, Jon D. Shuman, John E. Coligan, William H. Brooks, Thomas L. Roszman, Gene M. Shearer
Journal: The Journal of Immunology
J Immunol (1999) 162 (8): 4882–4892.
https://doi.org/10.4049/jimmunol.162.8.4882
Published: 15 April 1999
View article titled, Human Glioma-Induced Immunosuppression Involves Soluble Factor(s) That Alters Monocyte Cytokine Profile and Surface Markers
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Journal Articles

Cutting Edge: HIV-1 Infection Induces a Selective Reduction in STAT5 Protein Expression

Federica Pericle, Ligia A. Pinto, Stuart Hicks, Robert A. Kirken, Giuseppe Sconocchia, Janice Rusnak, Matthew J. Dolan, Gene M. Shearer, David M. Segal
Journal: The Journal of Immunology
J Immunol (1998) 160 (1): 28–31.
https://doi.org/10.4049/jimmunol.160.1.28
Published: 01 January 1998
View article titled, Cutting Edge: HIV-1 Infection Induces a Selective Reduction in STAT5 Protein Expression
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Journal Articles

Cerebrospinal fluid cytokines in pediatric neuropsychiatric disease.

B B Mittleman, F X Castellanos, L K Jacobsen, J L Rapoport, S E Swedo, G M Shearer
Journal: The Journal of Immunology
J Immunol (1997) 159 (6): 2994–2999.
https://doi.org/10.4049/jimmunol.159.6.2994
Published: 15 September 1997
View article titled, Cerebrospinal fluid cytokines in pediatric neuropsychiatric disease.
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Journal Articles

Kinetics of cytokine production in experimental systemic lupus erythematosus: involvement of T helper cell 1/T helper cell 2-type cytokines in disease.

R Segal, B L Bermas, M Dayan, F Kalush, G M Shearer, E Mozes
Journal: The Journal of Immunology
J Immunol (1997) 158 (6): 3009–3016.
https://doi.org/10.4049/jimmunol.158.6.3009
Published: 15 March 1997
View article titled, Kinetics of cytokine production in experimental systemic lupus erythematosus: involvement of T helper cell 1/T helper cell 2-type cytokines in disease.
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Journal Articles

Self-thyroid epithelial cell (TEC)-reactive CD8+ T cell lines/clones derived from autoimmune thyroiditis lesions. They recognize self-thyroid antigens directly on TEC to exhibit T helper cell 1-type lymphokine production and cytotoxicity against TEC.

S Sugihara, H Fujiwara, H Niimi, G M Shearer
Journal: The Journal of Immunology
J Immunol (1995) 155 (3): 1619–1628.
https://doi.org/10.4049/jimmunol.155.3.1619
Published: 01 August 1995
View article titled, Self-thyroid epithelial cell (TEC)-reactive CD8+ T cell lines/clones derived from autoimmune thyroiditis lesions. They recognize self-thyroid antigens directly on TEC to exhibit T helper cell 1-type lymphokine production and cytotoxicity against TEC.
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Journal Articles

Functional studies of epidermal Langerhans cells and blood monocytes in HIV-infected persons.

A Blauvelt, M Clerici, D R Lucey, S M Steinberg, R Yarchoan, R Walker, G M Shearer, S I Katz
Journal: The Journal of Immunology
J Immunol (1995) 154 (7): 3506–3515.
https://doi.org/10.4049/jimmunol.154.7.3506
Published: 01 April 1995
View article titled, Functional studies of epidermal Langerhans cells and blood monocytes in HIV-infected persons.
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Journal Articles

Inhibition of activation-induced programmed cell death and restoration of defective immune responses of HIV+ donors by cysteine protease inhibitors.

A Sarin, M Clerici, S P Blatt, C W Hendrix, G M Shearer, P A Henkart
Journal: The Journal of Immunology
J Immunol (1994) 153 (2): 862–872.
https://doi.org/10.4049/jimmunol.153.2.862
Published: 15 July 1994
View article titled, Inhibition of activation-induced programmed cell death and restoration of defective immune responses of HIV+ donors by cysteine protease inhibitors.
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Journal Articles

Recovery of T cell populations after acute graft-vs-host reaction.

F T Hakim, S Payne, G M Shearer
Journal: The Journal of Immunology
J Immunol (1994) 152 (1): 58–64.
https://doi.org/10.4049/jimmunol.152.1.58
Published: 01 January 1994
View article titled, Recovery of T cell populations after acute graft-vs-host reaction.
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Journal Articles

T cell-antigen-presenting cell interactions in human systemic lupus erythematosus. Evidence for heterogeneous expression of multiple defects.

C S Via, G C Tsokos, B Bermas, M Clerici, G M Shearer
Journal: The Journal of Immunology
J Immunol (1993) 151 (7): 3914–3922.
https://doi.org/10.4049/jimmunol.151.7.3914
Published: 01 October 1993
View article titled, T cell-antigen-presenting cell interactions in human systemic lupus erythematosus. Evidence for heterogeneous expression of multiple defects.
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Journal Articles

Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. Characterization of thyroiditis-inducing T cell lines and clones derived from thyroid lesions.

S Sugihara, H Fujiwara, G M Shearer
Journal: The Journal of Immunology
J Immunol (1993) 150 (2): 683–694.
https://doi.org/10.4049/jimmunol.150.2.683
Published: 15 January 1993
View article titled, Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. Characterization of thyroiditis-inducing T cell lines and clones derived from thyroid lesions.
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Journal Articles

CD8+ T cells from mice vaccinated against Toxoplasma gondii are cytotoxic for parasite-infected or antigen-pulsed host cells.

F T Hakim, R T Gazzinelli, E Denkers, S Hieny, G M Shearer, A Sher
Journal: The Journal of Immunology
J Immunol (1991) 147 (7): 2310–2316.
https://doi.org/10.4049/jimmunol.147.7.2310
Published: 01 October 1991
View article titled, CD8+ T cells from mice vaccinated against Toxoplasma gondii are cytotoxic for parasite-infected or antigen-pulsed host cells.
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