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Manfred Wuhrer
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Journal Articles

IgG Fab Glycans Hinder FcRn-Mediated Placental Transport

Mikhail Volkov, Maximilian Brinkhaus, Karin A. van Schie, Albert Bondt, Theresa Kissel, Elvera J. van der Kooi, Arthur E. H. Bentlage, Carolien A. M. Koeleman, Steven W. de Taeye, Ninotska I. Derksen, Radboud J. E. M. Dolhain, Ute Braig-Scherer, Tom W. J. Huizinga, Manfred Wuhrer, René E. M. Toes, Gestur Vidarsson, Diane van der Woude
Journal: The Journal of Immunology
J Immunol (2023) 210 (2): 158–167.
https://doi.org/10.4049/jimmunol.2200438
Published: 15 January 2023
View article titled, IgG Fab Glycans Hinder FcRn-Mediated Placental Transport
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Includes: Supplementary data
Journal Articles

Fc Galactosylation Promotes Hexamerization of Human IgG1, Leading to Enhanced Classical Complement Activation

Thijs L. J. van Osch, Jan Nouta, Ninotska I. L. Derksen, Gerard van Mierlo, C. Ellen van der Schoot, Manfred Wuhrer, Theo Rispens, Gestur Vidarsson
Journal: The Journal of Immunology
J Immunol (2021) 207 (6): 1545–1554.
https://doi.org/10.4049/jimmunol.2100399
Published: 15 September 2021
View article titled, Fc Galactosylation Promotes Hexamerization of Human IgG1, Leading to Enhanced Classical Complement Activation
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Includes: Supplementary data
Journal Articles

Functional Attributes of Antibodies, Effector Cells, and Target Cells Affecting NK Cell–Mediated Antibody-Dependent Cellular Cytotoxicity

A. Robin Temming, Steven W. de Taeye, Erik L. de Graaf, Louise A. de Neef, Gillian Dekkers, Christine W. Bruggeman, Jana Koers, Peter Ligthart, Sietse Q. Nagelkerke, James C. Zimring, Taco W. Kuijpers, Manfred Wuhrer, Theo Rispens, Gestur Vidarsson
Journal: The Journal of Immunology
J Immunol (2019) 203 (12): 3126–3135.
https://doi.org/10.4049/jimmunol.1900985
Published: 15 December 2019
View article titled, Functional Attributes of Antibodies, Effector Cells, and Target Cells Affecting NK Cell–Mediated Antibody-Dependent Cellular Cytotoxicity
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Includes: Supplementary data
Journal Articles

Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile

Christine W. Bruggeman, Gillian Dekkers, Arthur E. H. Bentlage, Louise W. Treffers, Sietse Q. Nagelkerke, Suzanne Lissenberg-Thunnissen, Carolien A. M. Koeleman, Manfred Wuhrer, Timo K. van den Berg, Theo Rispens, Gestur Vidarsson, Taco W. Kuijpers
Journal: The Journal of Immunology
J Immunol (2017) 199 (1): 204–211.
https://doi.org/10.4049/jimmunol.1700116
Published: 01 July 2017
View article titled, Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile
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