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Marcus Altfeld
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Journal Articles

Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection

In Special Collection:
COVID-19, SARS, and MERS Articles
Jöran Lücke, Fabian Heinrich, Jakob Malsy, Nicholas Meins, Josa Schnell, Marius Böttcher, Mikolaj Nawrocki, Tao Zhang, Franziska Bertram, Morsal Sabihi, Jan Kempski, Tom Blankenburg, Anna Duprée, Matthias Reeh, Stefan Wolter, Oliver Mann, Jakob R. Izbicki, Ansgar W. Lohse, Nicola Gagliani, Marc Lütgehetmann, Madeleine J. Bunders, Marcus Altfeld, Guido Sauter, Anastasios D. Giannou, Susanne Krasemann, Benjamin Ondruschka, Samuel Huber
Journal: The Journal of Immunology
J Immunol (2023) 211 (6): 1052–1061.
https://doi.org/10.4049/jimmunol.2200844
Published: 09 August 2023
View articletitled, Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection
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Includes: Supplementary data
Journal Articles

Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation

Christine D. Palmer, Marisol Romero-Tejeda, Michael Sirignano, Siddhartha Sharma, Todd M. Allen, Marcus Altfeld, Stephanie Jost
Journal: The Journal of Immunology
J Immunol (2016) 196 (2): 668–677.
https://doi.org/10.4049/jimmunol.1501888
Published: 15 January 2016
View articletitled, Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation
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Includes: Supplementary data
Journal Articles

Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women

Morgane Griesbeck, Susanne Ziegler, Sophie Laffont, Nikaïa Smith, Lise Chauveau, Phillip Tomezsko, Armon Sharei, Georgio Kourjian, Filippos Porichis, Meghan Hart, Christine D. Palmer, Michael Sirignano, Claudia Beisel, Heike Hildebrandt, Claire Cénac, Alexandra-Chloé Villani, Thomas J. Diefenbach, Sylvie Le Gall, Olivier Schwartz, Jean-Philippe Herbeuval, Brigitte Autran, Jean-Charles Guéry, J. Judy Chang, Marcus Altfeld
Journal: The Journal of Immunology
J Immunol (2015) 195 (11): 5327–5336.
https://doi.org/10.4049/jimmunol.1501684
Published: 01 December 2015
View articletitled, Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women
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Includes: Supplementary data
Journal Articles

In vivo plasma LPS levels in HIV negative subjects alter T cell proliferative responses, stimulate cytokine release and induce TLR cross tolerance in monocytes ex vivo (IRC4P.604)

Christine Palmer, Marisol Romero-Tejeda, Michael Sirignano, Siddhartha Sharma, Todd Allen, Marcus Altfeld, Stephanie Jost
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 57.21.
https://doi.org/10.4049/jimmunol.194.Supp.57.21
Published: 01 May 2015
View articletitled, In vivo plasma LPS levels in HIV negative subjects alter T cell proliferative responses, stimulate cytokine release and induce TLR cross tolerance in monocytes ex vivo (IRC4P.604)
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Journal Articles

Early HIV-1 infection differentially alters responses of KIR-expressing Natural Killer cells in individuals carrying cognate HLA-C haplotypes (P6203)

Christian Korner, Mitchell Granoff, Molly Amero, Stephanie Jost, Marcus Altfeld
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 118.25.
https://doi.org/10.4049/jimmunol.190.Supp.118.25
Published: 01 May 2013
View articletitled, Early HIV-1 infection differentially alters responses of KIR-expressing Natural Killer cells in individuals carrying cognate HLA-C haplotypes (P6203)
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Journal Articles

Impact of NK cells on control of HIV infection in humanized BLT mice (P6207)

Stephanie Jost, Judy Chang, Keith Rands, Phillip Tomezsko, Erin Doyle, Romain Daillere, Timothy Dudek, Vladimir Vrbanac, Todd Allen, Andrew Tager, Marcus Altfeld
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 118.27.
https://doi.org/10.4049/jimmunol.190.Supp.118.27
Published: 01 May 2013
View articletitled, Impact of NK cells on control of HIV infection in humanized BLT mice (P6207)
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Journal Articles

Higher expression of several interferon-stimulated genes in HIV-1-infected females after adjusting for the level of viral replication (P3039)

J. Judy Chang, Matt Woods, Robert Lindsay, Erin Doyle, Morgane Griesbeck, Ellen Chan, Gregory Robbins, Ronald Bosch, Marcus Altfeld
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 55.20.
https://doi.org/10.4049/jimmunol.190.Supp.55.20
Published: 01 May 2013
View articletitled, Higher expression of several interferon-stimulated genes in HIV-1-infected females after adjusting for the level of viral replication (P3039)
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Journal Articles

Sex differences in IRF5 levels and implications for pDC IFNα response (P1365)

Morgane Griesbeck, Phillip Tomezsko, Erin Doyle, Michael Sirignano, Thomas Diefenbach, Marcus Altfeld, J. Judy Chang
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 63.36.
https://doi.org/10.4049/jimmunol.190.Supp.63.36
Published: 01 May 2013
View articletitled, Sex differences in IRF5 levels and implications for pDC IFNα response (P1365)
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Journal Articles

Inherent baseline levels of phosphorylated IRF7 impact pDC IFNα response to TLR7 stimulation (108.8)

Morgane Griesbeck, Erin Doyle, Robert Lindsay, Julie Boucau, Sylvie LeGall, Marcus Altfeld, J. Judy Chang
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 108.8.
https://doi.org/10.4049/jimmunol.188.Supp.108.8
Published: 01 May 2012
View articletitled, Inherent baseline levels of phosphorylated IRF7 impact pDC IFNα response to TLR7 stimulation (108.8)
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Journal Articles

Modification of immune activation in HIV-1-infected humanized mouse model using TLR7/9 antagonists (113.19)

J. Judy Chang, Robert Lindsay, Erin Doyle, Vladimir Vrbanac, Edward Seung, Timothy Dudek, Melissa Precopio, Ekambar Kandimalla, Andrew Tager, Marcus Altfeld
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 113.19.
https://doi.org/10.4049/jimmunol.188.Supp.113.19
Published: 01 May 2012
View articletitled, Modification of immune activation in HIV-1-infected humanized mouse model using TLR7/9 antagonists (113.19)
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Journal Articles

Novel KIR3DL1 Alleles and Their Expression Levels on NK Cells: Convergent Evolution of KIR3DL1 Phenotype Variation?

Rasmi Thomas, Eriko Yamada, Galit Alter, Maureen P. Martin, Arman A. Bashirova, Paul J. Norman, Marcus Altfeld, Peter Parham, Stephen K. Anderson, Daniel W. McVicar, Mary Carrington
Journal: The Journal of Immunology
J Immunol (2008) 180 (10): 6743–6750.
https://doi.org/10.4049/jimmunol.180.10.6743
Published: 15 May 2008
View articletitled, Novel KIR3DL1 Alleles and Their Expression Levels on NK Cells: Convergent Evolution of KIR3DL1 Phenotype Variation?
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Journal Articles

Detection of KIR3DS1 on the Cell Surface of Peripheral Blood NK Cells Facilitates Identification of a Novel Null Allele and Assessment of KIR3DS1 Expression during HIV-1 Infection

Véronique Pascal, Eriko Yamada, Maureen P. Martin, Galit Alter, Marcus Altfeld, Julia A. Metcalf, Michael W. Baseler, Joseph W. Adelsberger, Mary Carrington, Stephen K. Anderson, Daniel W. McVicar
Journal: The Journal of Immunology
J Immunol (2007) 179 (3): 1625–1633.
https://doi.org/10.4049/jimmunol.179.3.1625
Published: 01 August 2007
View articletitled, Detection of KIR3DS1 on the Cell Surface of Peripheral Blood NK Cells Facilitates Identification of a Novel Null Allele and Assessment of KIR3DS1 Expression during HIV-1 Infection
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Journal Articles

Single-Stranded RNA Derived from HIV-1 Serves as a Potent Activator of NK Cells

Galit Alter, Todd J. Suscovich, Nickolas Teigen, Angela Meier, Hendrik Streeck, Christian Brander, Marcus Altfeld
Journal: The Journal of Immunology
J Immunol (2007) 178 (12): 7658–7666.
https://doi.org/10.4049/jimmunol.178.12.7658
Published: 15 June 2007
View articletitled, Single-Stranded RNA Derived from HIV-1 Serves as a Potent Activator of NK Cells
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Journal Articles

Availability of a Diversely Avid CD8+ T Cell Repertoire Specific for the Subdominant HLA-A2-Restricted HIV-1 Gag p2419–27 Epitope

Keri L. Schaubert, David A. Price, Nicole Frahm, Jinzhu Li, Hwee L. Ng, Aviva Joseph, Elyse Paul, Biswanath Majumder, Velpandi Ayyavoo, Emma Gostick, Sharon Adams, Francesco M. Marincola, Andrew K. Sewell, Marcus Altfeld, Jason M. Brenchley, Daniel C. Douek, Otto O. Yang, Christian Brander, Harris Goldstein, June Kan-Mitchell
Journal: The Journal of Immunology
J Immunol (2007) 178 (12): 7756–7766.
https://doi.org/10.4049/jimmunol.178.12.7756
Published: 15 June 2007
View articletitled, Availability of a Diversely Avid CD8+ T Cell Repertoire Specific for the Subdominant HLA-A2-Restricted HIV-1 Gag p2419–27 Epitope
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Journal Articles

Functional evidence supporting the predicted role of KIR3DS1 in the host response to HIV: KIR3DS1 is an activating receptor expressed by human Natural Killer cells (52.5)

Veronique Pascal, Eriko Yamada, Maureen P Martin, Galit Alter, Marcus Altfeld, Mary Carrington, Stephen K Anderson, Daniel W McVicar
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S100.
https://doi.org/10.4049/jimmunol.178.Supp.52.5
Published: 01 April 2007
View articletitled, Functional evidence supporting the predicted role of KIR3DS1 in the host response to HIV: KIR3DS1 is an activating receptor expressed by human Natural Killer cells (52.5)
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Journal Articles

HIV-1 Viral Escape in Infancy Followed by Emergence of a Variant-Specific CTL Response

Margaret E. Feeney, Yanhua Tang, Katja Pfafferott, Kathleen A. Roosevelt, Rika Draenert, Alicja Trocha, Xu G. Yu, Cori Verrill, Todd Allen, Corey Moore, Simon Mallal, Sandra Burchett, Kenneth McIntosh, Stephen I. Pelton, M. Anne St. John, Rohan Hazra, Paul Klenerman, Marcus Altfeld, Bruce D. Walker, Philip J. R. Goulder
Journal: The Journal of Immunology
J Immunol (2005) 174 (12): 7524–7530.
https://doi.org/10.4049/jimmunol.174.12.7524
Published: 15 June 2005
View articletitled, HIV-1 Viral Escape in Infancy Followed by Emergence of a Variant-Specific CTL Response
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Journal Articles

Increased Natural Killer Cell Activity in Viremic HIV-1 Infection

Galit Alter, Jessica M. Malenfant, Rosemary M. Delabre, Nicole C. Burgett, Xu G. Yu, Mathias Lichterfeld, John Zaunders, Marcus Altfeld
Journal: The Journal of Immunology
J Immunol (2004) 173 (8): 5305–5311.
https://doi.org/10.4049/jimmunol.173.8.5305
Published: 15 October 2004
View articletitled, Increased Natural Killer Cell Activity in Viremic HIV-1 Infection
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Journal Articles

Viremia Control Despite Escape from a Rapid and Potent Autologous Neutralizing Antibody Response After Therapy Cessation in an HIV-1-Infected Individual

David C. Montefiori, Marcus Altfeld, Paul K. Lee, Miroslawa Bilska, Jintao Zhou, Mary N. Johnston, Feng Gao, Bruce D. Walker, Eric S. Rosenberg
Journal: The Journal of Immunology
J Immunol (2003) 170 (7): 3906–3914.
https://doi.org/10.4049/jimmunol.170.7.3906
Published: 01 April 2003
View articletitled, Viremia Control Despite Escape from a Rapid and Potent Autologous Neutralizing Antibody Response After Therapy Cessation in an HIV-1-Infected Individual
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Journal Articles

Vpr Is Preferentially Targeted by CTL During HIV-1 Infection

Marcus Altfeld, Marylyn M. Addo, Robert L. Eldridge, Xu G. Yu, Seddon Thomas, Ashok Khatri, Daryld Strick, Mary N. Phillips, George B. Cohen, Sabina A. Islam, Spyros A. Kalams, Christian Brander, Philip J. R. Goulder, Eric S. Rosenberg, Bruce D. Walker, the HIV Study Collaboration
Journal: The Journal of Immunology
J Immunol (2001) 167 (5): 2743–2752.
https://doi.org/10.4049/jimmunol.167.5.2743
Published: 01 September 2001
View articletitled, Vpr Is Preferentially Targeted by CTL During HIV-1 Infection
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