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Marcus Groettrup
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Journal Articles

Immunoproteasome Upregulation Is Not Required to Control Protein Homeostasis during Viral Infection

Michael Basler, Marleen Christ, Heike Goebel, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2021) 206 (8): 1697–1708.
https://doi.org/10.4049/jimmunol.2000822
Published: 15 April 2021
View article titled, Immunoproteasome Upregulation Is Not Required to Control Protein Homeostasis during Viral Infection
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Journal Articles

Immunoproteasome Inhibition Selectively Kills Human CD14+ Monocytes and as a Result Dampens IL-23 Secretion

Michael Basler, Meike Claus, Moritz Klawitter, Heike Goebel, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2019) 203 (7): 1776–1785.
https://doi.org/10.4049/jimmunol.1900182
Published: 01 October 2019
View article titled, Immunoproteasome Inhibition Selectively Kills Human CD14<sup>+</sup> Monocytes and as a Result Dampens IL-23 Secretion
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Includes: Supplementary data
Journal Articles

The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection

Stefanie Buerger, Valerie L. Herrmann, Sarah Mundt, Nico Trautwein, Marcus Groettrup, Michael Basler
Journal: The Journal of Immunology
J Immunol (2015) 195 (9): 4106–4116.
https://doi.org/10.4049/jimmunol.1500592
Published: 01 November 2015
View article titled, The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection
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Includes: Supplementary data
Journal Articles

Immunoproteasome Subunit LMP7 Deficiency and Inhibition Suppresses Th1 and Th17 but Enhances Regulatory T Cell Differentiation

Khalid W. Kalim, Michael Basler, Christopher J. Kirk, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2012) 189 (8): 4182–4193.
https://doi.org/10.4049/jimmunol.1201183
Published: 15 October 2012
View article titled, Immunoproteasome Subunit LMP7 Deficiency and Inhibition Suppresses Th1 and Th17 but Enhances Regulatory T Cell Differentiation
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Includes: Supplementary data
Journal Articles

Why the Structure but Not the Activity of the Immunoproteasome Subunit Low Molecular Mass Polypeptide 2 Rescues Antigen Presentation

Michael Basler, Christoph Lauer, Jacqueline Moebius, Reinhold Weber, Michael Przybylski, Alexei F. Kisselev, Christopher Tsu, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2012) 189 (4): 1868–1877.
https://doi.org/10.4049/jimmunol.1103592
Published: 15 August 2012
View article titled, Why the Structure but Not the Activity of the Immunoproteasome Subunit Low Molecular Mass Polypeptide 2 Rescues Antigen Presentation
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Journal Articles

The Antiviral Immune Response in Mice Devoid of Immunoproteasome Activity

Michael Basler, Ulrike Beck, Christopher J. Kirk, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2011) 187 (11): 5548–5557.
https://doi.org/10.4049/jimmunol.1101064
Published: 01 December 2011
View article titled, The Antiviral Immune Response in Mice Devoid of Immunoproteasome Activity
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Journal Articles

Cross-Talk Between TCR and CCR7 Signaling Sets a Temporal Threshold for Enhanced T Lymphocyte Migration

Karin Schaeuble, Mark A. Hauser, Eva Singer, Marcus Groettrup, Daniel F. Legler
Journal: The Journal of Immunology
J Immunol (2011) 187 (11): 5645–5652.
https://doi.org/10.4049/jimmunol.1101850
Published: 01 December 2011
View article titled, Cross-Talk Between TCR and CCR7 Signaling Sets a Temporal Threshold for Enhanced T Lymphocyte Migration
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Journal Articles

CD8− Dendritic Cells and Macrophages Cross-Present Poly(D,L-lactate-co-glycolate) Acid Microsphere-Encapsulated Antigen In Vivo

Christopher Schliehe, Chiara Redaelli, Sabrina Engelhardt, Michael Fehlings, Marc Mueller, Nico van Rooijen, Marc Thiry, Kai Hildner, Horst Weller, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2011) 187 (5): 2112–2121.
https://doi.org/10.4049/jimmunol.1002084
Published: 01 September 2011
View article titled, CD8<sup>−</sup> Dendritic Cells and Macrophages Cross-Present Poly(D,L-lactate-<em>co</em>-glycolate) Acid Microsphere-Encapsulated Antigen In Vivo
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Includes: Supplementary data
Journal Articles

Reduced Immunoproteasome Formation and Accumulation of Immunoproteasomal Precursors in the Brains of Lymphocytic Choriomeningitis Virus-Infected Mice

Marcel Kremer, Anja Henn, Cornelia Kolb, Michael Basler, Jacqueline Moebius, Benoît Guillaume, Marcel Leist, Benoît J. Van den Eynde, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2010) 185 (9): 5549–5560.
https://doi.org/10.4049/jimmunol.1001517
Published: 01 November 2010
View article titled, Reduced Immunoproteasome Formation and Accumulation of Immunoproteasomal Precursors in the Brains of Lymphocytic Choriomeningitis Virus-Infected Mice
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Includes: Supplementary data
Journal Articles

Prevention of Experimental Colitis by a Selective Inhibitor of the Immunoproteasome

Michael Basler, Maya Dajee, Carlo Moll, Marcus Groettrup, Christopher J. Kirk
Journal: The Journal of Immunology
J Immunol (2010) 185 (1): 634–641.
https://doi.org/10.4049/jimmunol.0903182
Published: 01 July 2010
View article titled, Prevention of Experimental Colitis by a Selective Inhibitor of the Immunoproteasome
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Includes: Supplementary data
Journal Articles

The Proteasome Inhibitor Bortezomib Enhances the Susceptibility to Viral Infection

Michael Basler, Christoph Lauer, Ulrike Beck, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2009) 183 (10): 6145–6150.
https://doi.org/10.4049/jimmunol.0901596
Published: 15 November 2009
View article titled, The Proteasome Inhibitor Bortezomib Enhances the Susceptibility to Viral Infection
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Journal Articles

Pillars Article: Analysis and Expression of a Cloned Pre-T Cell Receptor Gene. Science. 1994. 266: 1208–1212

Claude Saint-Ruf, Katharina Ungewiss, Marcus Groettrup, Ludovica Bruno, Hans Joerg Fehling, Harald von Boehmer
Journal: The Journal of Immunology
J Immunol (2009) 182 (9): 5165–5169.
Published: 01 May 2009
View article titled, Pillars Article: Analysis and Expression of a Cloned Pre-T Cell Receptor Gene. Science. 1994. 266: 1208–1212
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Journal Articles

Opposite Fate of Endocytosed CCR7 and Its Ligands: Recycling versus Degradation

Carolina Otero, Marcus Groettrup, Daniel F. Legler
Journal: The Journal of Immunology
J Immunol (2006) 177 (4): 2314–2323.
https://doi.org/10.4049/jimmunol.177.4.2314
Published: 15 August 2006
View article titled, Opposite Fate of Endocytosed CCR7 and Its Ligands: Recycling versus Degradation
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Journal Articles

An Altered T Cell Repertoire in MECL-1-Deficient Mice

Michael Basler, Jacqueline Moebius, Laura Elenich, Marcus Groettrup, John J. Monaco
Journal: The Journal of Immunology
J Immunol (2006) 176 (11): 6665–6672.
https://doi.org/10.4049/jimmunol.176.11.6665
Published: 01 June 2006
View article titled, An Altered T Cell Repertoire in MECL-1-Deficient Mice
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Journal Articles

Prostaglandin E2 Is Generally Required for Human Dendritic Cell Migration and Exerts Its Effect via EP2 and EP4 Receptors

Daniel F. Legler, Petra Krause, Elke Scandella, Eva Singer, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2006) 176 (2): 966–973.
https://doi.org/10.4049/jimmunol.176.2.966
Published: 15 January 2006
View article titled, Prostaglandin E<sub>2</sub> Is Generally Required for Human Dendritic Cell Migration and Exerts Its Effect via EP2 and EP4 Receptors
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Journal Articles

Cross-Presentation of the Long-Lived Lymphocytic Choriomeningitis Virus Nucleoprotein Does Not Require Neosynthesis and Is Enhanced via Heat Shock Proteins

Sameh Basta, Ricarda Stoessel, Michael Basler, Maries van den Broek, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2005) 175 (2): 796–805.
https://doi.org/10.4049/jimmunol.175.2.796
Published: 15 July 2005
View article titled, Cross-Presentation of the Long-Lived Lymphocytic Choriomeningitis Virus Nucleoprotein Does Not Require Neosynthesis and Is Enhanced via Heat Shock Proteins
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Journal Articles

Immunoproteasomes Down-Regulate Presentation of a Subdominant T Cell Epitope from Lymphocytic Choriomeningitis Virus

Michael Basler, Nikolay Youhnovski, Maries van den Broek, Michael Przybylski, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2004) 173 (6): 3925–3934.
https://doi.org/10.4049/jimmunol.173.6.3925
Published: 15 September 2004
View article titled, Immunoproteasomes Down-Regulate Presentation of a Subdominant T Cell Epitope from Lymphocytic Choriomeningitis Virus
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Journal Articles

Immunoproteasomes Largely Replace Constitutive Proteasomes During an Antiviral and Antibacterial Immune Response in the Liver

Selina Khan, Maries van den Broek, Katrin Schwarz, Rita de Giuli, Pierre-André Diener, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2001) 167 (12): 6859–6868.
https://doi.org/10.4049/jimmunol.167.12.6859
Published: 15 December 2001
View article titled, Immunoproteasomes Largely Replace Constitutive Proteasomes During an Antiviral and Antibacterial Immune Response in the Liver
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Journal Articles

Cutting Edge: Neosynthesis Is Required for the Presentation of a T Cell Epitope from a Long-Lived Viral Protein

Selina Khan, Rita de Giuli, Gunter Schmidtke, Michael Bruns, Michael Buchmeier, Maries van den Broek, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2001) 167 (9): 4801–4804.
https://doi.org/10.4049/jimmunol.167.9.4801
Published: 01 November 2001
View article titled, Cutting Edge: Neosynthesis Is Required for the Presentation of a T Cell Epitope from a Long-Lived Viral Protein
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Journal Articles

Overexpression of the Proteasome Subunits LMP2, LMP7, and MECL-1, But Not PA28α/β, Enhances the Presentation of an Immunodominant Lymphocytic Choriomeningitis Virus T Cell Epitope

Katrin Schwarz, Maries van den Broek, Susanne Kostka, Regine Kraft, Andrea Soza, Gunter Schmidtke, Peter-M. Kloetzel, Marcus Groettrup
Journal: The Journal of Immunology
J Immunol (2000) 165 (2): 768–778.
https://doi.org/10.4049/jimmunol.165.2.768
Published: 15 July 2000
View article titled, Overexpression of the Proteasome Subunits LMP2, LMP7, and MECL-1, But Not PA28α/β, Enhances the Presentation of an Immunodominant Lymphocytic Choriomeningitis Virus T Cell Epitope
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