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Martin Felices
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Journal Articles

Ablation of SYK Kinase from Expanded Primary Human NK Cells via CRISPR/Cas9 Enhances Cytotoxicity and Cytokine Production

James D. Dahlvang, Jenna K. Dick, Jules A. Sangala, Philippa R. Kennedy, Emily J. Pomeroy, Kristin M. Snyder, Juliette M. Moushon, Claire E. Thefaine, Jianming Wu, Sara E. Hamilton, Martin Felices, Jeffrey S. Miller, Bruce Walcheck, Beau R. Webber, Branden S. Moriarity, Geoffrey T. Hart
Journal: The Journal of Immunology
J Immunol (2023) 210 (8): 1108–1122.
https://doi.org/10.4049/jimmunol.2200488
Published: 06 March 2023
View article titled, Ablation of SYK Kinase from Expanded Primary Human NK Cells via CRISPR/Cas9 Enhances Cytotoxicity and Cytokine Production
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Includes: Supplementary data
Journal Articles

Hypoxia profoundly alters Natural Killer cell phenotype and function: implications for immunotherapy within the solid tumor microenvironment

Upasana Sunil Arvindam, Philippa Kennedy, Brianna Ettestad, Shee Kwan Phung, Peter Hinderlie, James Lim, Jeffrey S Miller, Martin Felices
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 56.17.
https://doi.org/10.4049/jimmunol.206.Supp.56.17
Published: 01 May 2021
View article titled, Hypoxia profoundly alters Natural Killer cell phenotype and function: implications for immunotherapy within the solid tumor microenvironment
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Journal Articles

Synergistic activity between IL-15 signaling and checkpoint blockade drives enhanced NK cell expansion and tumor control in ovarian cancer

Martin Felices, Laura Bendzick, Behiye Kodal, Peter Hinderlie, Jeffrey S Miller, Melissa Geller
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 136.22.
https://doi.org/10.4049/jimmunol.202.Supp.136.22
Published: 01 May 2019
View article titled, Synergistic activity between IL-15 signaling and checkpoint blockade drives enhanced NK cell expansion and tumor control in ovarian cancer
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Journal Articles

CD16-IL15-CD33 Trispecific Killer Engager (TriKE) induces NK cell expansion, persistence, and myeloid blast antigen specific killing.

Martin Felices, Daniel A. Vallera, Ron McElmurry, Alexander J.L. Lenvik, Sami Chu, Deborah Todhunter, Elizabeth P. Taras, Jakub Tolar, Bruce R Blazar, Jeffrey S Miller
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 75.8.
https://doi.org/10.4049/jimmunol.196.Supp.75.8
Published: 01 May 2016
View article titled, CD16-IL15-CD33 Trispecific Killer Engager (TriKE) induces NK cell expansion, persistence, and myeloid blast antigen specific killing.
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Journal Articles

Notch Signaling at Later Stages of NK Cell Development Enhances KIR Expression and Functional Maturation

Martin Felices, Dave E. M. Ankarlo, Todd R. Lenvik, Heather H. Nelson, Bruce R. Blazar, Michael R. Verneris, Jeffrey S. Miller
Journal: The Journal of Immunology
J Immunol (2014) 193 (7): 3344–3354.
https://doi.org/10.4049/jimmunol.1400534
Published: 01 October 2014
View article titled, Notch Signaling at Later Stages of NK Cell Development Enhances KIR Expression and Functional Maturation
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Includes: Supplementary data
Journal Articles

Notch modulates human NK cell differentiation through regulation of inhibitory killer immunoglobulin-like receptor (KIR) expression and acquisition of effector function (TUM2P.890)

Martin Felices, Dave Ankarlo, Todd Lenvik, Jeffrey Miller
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 71.14.
https://doi.org/10.4049/jimmunol.192.Supp.71.14
Published: 01 May 2014
View article titled, Notch modulates human NK cell differentiation through regulation of inhibitory killer immunoglobulin-like receptor (KIR) expression and acquisition of effector function (TUM2P.890)
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Journal Articles

Functional NK Cell Repertoires Are Maintained through IL-2Rα and Fas Ligand

Martin Felices, Todd R. Lenvik, Dave E. M. Ankarlo, Bree Foley, Julie Curtsinger, Xianghua Luo, Bruce R. Blazar, Stephen K. Anderson, Jeffrey S. Miller
Journal: The Journal of Immunology
J Immunol (2014) 192 (8): 3889–3897.
https://doi.org/10.4049/jimmunol.1302601
Published: 15 April 2014
View article titled, Functional NK Cell Repertoires Are Maintained through IL-2Rα and Fas Ligand
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Includes: Supplementary data
Journal Articles

Natural killer cell education results in prolonged survival through a cytokine receptor balance mediated mechanism (P1435)

Martin Felices, Todd Lenvik, Dave Ankarlo, Julie Curtsinger, Sarah Cooley, Jakub Tolar, Bruce Blazar, Stephen Anderson, Jeffrey Miller
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 60.9.
https://doi.org/10.4049/jimmunol.190.Supp.60.9
Published: 01 May 2013
View article titled, Natural killer cell education results in prolonged survival through a cytokine receptor balance mediated mechanism (P1435)
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Journal Articles

Cutting Edge: MicroRNA-181 Promotes Human NK Cell Development by Regulating Notch Signaling

Frank Cichocki, Martin Felices, Valarie McCullar, Steven R. Presnell, Ahmad Al-Attar, Charles T. Lutz, Jeffrey S. Miller
Journal: The Journal of Immunology
J Immunol (2011) 187 (12): 6171–6175.
https://doi.org/10.4049/jimmunol.1100835
Published: 15 December 2011
View article titled, Cutting Edge: MicroRNA-181 Promotes Human NK Cell Development by Regulating Notch Signaling
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Includes: Supplementary data
Journal Articles

Role of Itk in γδ T cell development and function (84.22)

Catherine C Yin, Martin Felices, Yoko Kosaka, Joonsoo Kang, Leslie J Berg
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 84.22.
https://doi.org/10.4049/jimmunol.182.Supp.84.22
Published: 01 April 2009
View article titled, Role of Itk in γδ T cell development and function (84.22)
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Journal Articles

The Tec Kinases Itk and Rlk Regulate NKT Cell Maturation, Cytokine Production, and Survival

Martin Felices, Leslie J. Berg
Journal: The Journal of Immunology
J Immunol (2008) 180 (5): 3007–3018.
https://doi.org/10.4049/jimmunol.180.5.3007
Published: 01 March 2008
View article titled, The Tec Kinases Itk and Rlk Regulate NKT Cell Maturation, Cytokine Production, and Survival
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Journal Articles

Subtle Defects in Pre-TCR Signaling in the Absence of the Tec Kinase Itk

Julie A. Lucas, Martin Felices, John W. Evans, Leslie J. Berg
Journal: The Journal of Immunology
J Immunol (2007) 179 (11): 7561–7567.
https://doi.org/10.4049/jimmunol.179.11.7561
Published: 01 December 2007
View article titled, Subtle Defects in Pre-TCR Signaling in the Absence of the Tec Kinase Itk
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