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Michael A. Beaven
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Journal Articles

Rictor Negatively Regulates High-Affinity Receptors for IgE-Induced Mast Cell Degranulation

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Daniel Smrz, Glenn Cruse, Michael A. Beaven, Arnold Kirshenbaum, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2014) 193 (12): 5924–5932.
https://doi.org/10.4049/jimmunol.1303495
Published: 15 December 2014
View articletitled, Rictor Negatively Regulates High-Affinity Receptors for IgE-Induced Mast Cell Degranulation
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Includes: Supplementary data
Journal Articles

IL-33 Induces a Hyporesponsive Phenotype in Human and Mouse Mast Cells

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Mi-Yeon Jung, Daniel Smrž, Avanti Desai, Geethani Bandara, Tomonobu Ito, Shoko Iwaki, Jeong-Han Kang, Marcus V. Andrade, Susana C. Hilderbrand, Jared M. Brown, Michael A. Beaven, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2013) 190 (2): 531–538.
https://doi.org/10.4049/jimmunol.1201576
Published: 15 January 2013
View articletitled, IL-33 Induces a Hyporesponsive Phenotype in Human and Mouse Mast Cells
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Includes: Supplementary data
Journal Articles

Stem Cell Factor Programs the Mast Cell Activation Phenotype

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Tomonobu Ito, Daniel Smrž, Mi-Yeon Jung, Geethani Bandara, Avanti Desai, Šárka Smržová, Hye Sun Kuehn, Michael A. Beaven, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2012) 188 (11): 5428–5437.
https://doi.org/10.4049/jimmunol.1103366
Published: 01 June 2012
View articletitled, Stem Cell Factor Programs the Mast Cell Activation Phenotype
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Includes: Supplementary data
Journal Articles

The Src Family Kinase Fgr Is Critical for Activation of Mast Cells and IgE-Mediated Anaphylaxis in Mice

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Jun Ho Lee, Jie Wan Kim, Do Kyun Kim, Hyuk Soon Kim, Hye Jin Park, Dong Ki Park, A-Ram Kim, Bokyung Kim, Michael A. Beaven, Kui Lea Park, Young Mi Kim, Wahn Soo Choi
Journal: The Journal of Immunology
J Immunol (2011) 187 (4): 1807–1815.
https://doi.org/10.4049/jimmunol.1100296
Published: 15 August 2011
View articletitled, The Src Family Kinase Fgr Is Critical for Activation of Mast Cells and IgE-Mediated Anaphylaxis in Mice
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Journal Articles

Phospholipase D Promotes Lipid Microdomain-Associated Signaling Events in Mast Cells

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Felipe A. Lisboa, Ze Peng, Christian A. Combs, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (2009) 183 (8): 5104–5112.
https://doi.org/10.4049/jimmunol.0802728
Published: 15 October 2009
View articletitled, Phospholipase D Promotes Lipid Microdomain-Associated Signaling Events in Mast Cells
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Journal Articles

The Phosphoinositide 3-Kinase-Dependent Activation of Btk Is Required for Optimal Eicosanoid Production and Generation of Reactive Oxygen Species in Antigen-Stimulated Mast Cells

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Hye Sun Kuehn, Emily J. Swindle, Mi-Sun Kim, Michael A. Beaven, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: The Journal of Immunology
J Immunol (2008) 181 (11): 7706–7712.
https://doi.org/10.4049/jimmunol.181.11.7706
Published: 01 December 2008
View articletitled, The Phosphoinositide 3-Kinase-Dependent Activation of Btk Is Required for Optimal Eicosanoid Production and Generation of Reactive Oxygen Species in Antigen-Stimulated Mast Cells
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Journal Articles

Canonical Transient Receptor Potential 5 Channel in Conjunction with Orai1 and STIM1 Allows Sr2+ Entry, Optimal Influx of Ca2+, and Degranulation in a Rat Mast Cell Line

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Hong-Tao Ma, Ze Peng, Takaaki Hiragun, Shoko Iwaki, Alasdair M. Gilfillan, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (2008) 180 (4): 2233–2239.
https://doi.org/10.4049/jimmunol.180.4.2233
Published: 15 February 2008
View articletitled, Canonical Transient Receptor Potential 5 Channel in Conjunction with Orai1 and STIM1 Allows Sr2+ Entry, Optimal Influx of Ca2+, and Degranulation in a Rat Mast Cell Line
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Journal Articles

Glucocorticoids Suppress Activation of Mast Cells through induction of Inhibitory Regulators of Signaling Pathways (94.13)

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Ze Peng, Takaaki Hiragun, Huihong Qiao, Michael A Beaven
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S173.
https://doi.org/10.4049/jimmunol.178.Supp.94.13
Published: 01 April 2007
View articletitled, Glucocorticoids Suppress Activation of Mast Cells through induction of Inhibitory Regulators of Signaling Pathways (94.13)
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Journal Articles

Cutting Edge: Dexamethasone Negatively Regulates Syk in Mast Cells by Up-Regulating Src-Like Adaptor Protein

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Takaaki Hiragun, Ze Peng, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (2006) 177 (4): 2047–2050.
https://doi.org/10.4049/jimmunol.177.4.2047
Published: 15 August 2006
View articletitled, Cutting Edge: Dexamethasone Negatively Regulates Syk in Mast Cells by Up-Regulating Src-Like Adaptor Protein
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Journal Articles

Cutting Edge: Lentiviral Short Hairpin RNA Silencing of PTEN in Human Mast Cells Reveals Constitutive Signals That Promote Cytokine Secretion and Cell Survival

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Yasuko Furumoto, Steve Brooks, Ana Olivera, Yasuomi Takagi, Makoto Miyagishi, Kazunari Taira, Rafael Casellas, Michael A. Beaven, Alasdair M. Gilfillan, Juan Rivera
Journal: The Journal of Immunology
J Immunol (2006) 176 (9): 5167–5171.
https://doi.org/10.4049/jimmunol.176.9.5167
Published: 01 May 2006
View articletitled, Cutting Edge: Lentiviral Short Hairpin RNA Silencing of PTEN in Human Mast Cells Reveals Constitutive Signals That Promote Cytokine Secretion and Cell Survival
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Journal Articles

An Essential Role for Phospholipase D in the Activation of Protein Kinase C and Degranulation in Mast Cells

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Ze Peng, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (2005) 174 (9): 5201–5208.
https://doi.org/10.4049/jimmunol.174.9.5201
Published: 01 May 2005
View articletitled, An Essential Role for Phospholipase D in the Activation of Protein Kinase C and Degranulation in Mast Cells
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Journal Articles

Dexamethasone Suppresses Antigen-Induced Activation of Phosphatidylinositol 3-Kinase and Downstream Responses in Mast Cells

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Marcus V. M. Andrade, Takaaki Hiragun, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (2004) 172 (12): 7254–7262.
https://doi.org/10.4049/jimmunol.172.12.7254
Published: 15 June 2004
View articletitled, Dexamethasone Suppresses Antigen-Induced Activation of Phosphatidylinositol 3-Kinase and Downstream Responses in Mast Cells
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Journal Articles

Phospholipases D1 and D2 Regulate Different Phases of Exocytosis in Mast Cells

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Wahn Soo Choi, Young Mi Kim, Christian Combs, Michael A. Frohman, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (2002) 168 (11): 5682–5689.
https://doi.org/10.4049/jimmunol.168.11.5682
Published: 01 June 2002
View articletitled, Phospholipases D1 and D2 Regulate Different Phases of Exocytosis in Mast Cells
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Journal Articles

Elevated Levels of Cyclooxygenase-2 in Antigen-Stimulated Mast Cells Is Associated with Minimal Activation of p38 Mitogen-Activated Protein Kinase

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Thomas R. Hundley, Anjana R. Prasad, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (2001) 167 (3): 1629–1636.
https://doi.org/10.4049/jimmunol.167.3.1629
Published: 01 August 2001
View articletitled, Elevated Levels of Cyclooxygenase-2 in Antigen-Stimulated Mast Cells Is Associated with Minimal Activation of p38 Mitogen-Activated Protein Kinase
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Journal Articles

Induction of Telomerase Activity During Development of Human Mast Cells from Peripheral Blood CD34+ Cells: Comparisons with Tumor Mast-Cell Lines

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Cristina Chaves-Dias, Thomas R. Hundley, Alasdair M. Gilfillan, Arnold S. Kirshenbaum, Jose Renan Cunha-Melo, Dean D. Metcalfe, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (2001) 166 (11): 6647–6656.
https://doi.org/10.4049/jimmunol.166.11.6647
Published: 01 June 2001
View articletitled, Induction of Telomerase Activity During Development of Human Mast Cells from Peripheral Blood CD34+ Cells: Comparisons with Tumor Mast-Cell Lines
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Journal Articles

Quercetin Sensitizes RBL-2H3 Cells to Polybasic Mast Cell Secretagogues Through Increased Expression of Gi GTP-Binding Proteins Linked to a Phospholipase C Signaling Pathway

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Jan Senyshyn, Rudolf A. Baumgartner, Michael A. Beaven
Journal: The Journal of Immunology
J Immunol (1998) 160 (10): 5136–5144.
https://doi.org/10.4049/jimmunol.160.10.5136
Published: 15 May 1998
View articletitled, Quercetin Sensitizes RBL-2H3 Cells to Polybasic Mast Cell Secretagogues Through Increased Expression of Gi GTP-Binding Proteins Linked to a Phospholipase C Signaling Pathway
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