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Moira K. B. Whyte
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Journal Articles

Serum and Glucocorticoid–Regulated Kinase 1 Regulates Neutrophil Clearance during Inflammation Resolution

Joseph Burgon, Anne L. Robertson, Pranvera Sadiku, Xingang Wang, Edward Hooper-Greenhill, Lynne R. Prince, Paul Walker, Emily E. Hoggett, Jonathan R. Ward, Stuart N. Farrow, William J. Zuercher, Philip Jeffrey, Caroline O. Savage, Philip W. Ingham, Adam F. Hurlstone, Moira K. B. Whyte, Stephen A. Renshaw
Journal: The Journal of Immunology
J Immunol (2014) 192 (4): 1796–1805.
DOI: https://doi.org/10.4049/jimmunol.1300087
Published: 15 February 2014
View article titled, Serum and Glucocorticoid–Regulated Kinase 1 Regulates Neutrophil Clearance during Inflammation Resolution
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Includes: Supplementary data
Journal Articles

Loss of the Oxygen Sensor PHD3 Enhances the Innate Immune Response to Abdominal Sepsis

Judit Kiss, Martin Mollenhauer, Sarah R. Walmsley, Johanna Kirchberg, Praveen Radhakrishnan, Thomas Niemietz, Johanna Dudda, Gunnar Steinert, Moira K. B. Whyte, Peter Carmeliet, Massimiliano Mazzone, Jürgen Weitz, Martin Schneider
Journal: The Journal of Immunology
J Immunol (2012) 189 (4): 1955–1965.
DOI: https://doi.org/10.4049/jimmunol.1103471
Published: 15 August 2012
View article titled, Loss of the Oxygen Sensor PHD3 Enhances the Innate Immune Response to Abdominal Sepsis
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Includes: Supplementary data
Journal Articles

Hypoxia Selectively Inhibits Respiratory Burst Activity and Killing of Staphylococcus aureus in Human Neutrophils

Naomi N. McGovern, Andrew S. Cowburn, Linsey Porter, Sarah R. Walmsley, Charlotte Summers, Alfred A. R. Thompson, Sadia Anwar, Lisa C. Willcocks, Moira K. B. Whyte, Alison M. Condliffe, Edwin R. Chilvers
Journal: The Journal of Immunology
J Immunol (2011) 186 (1): 453–463.
DOI: https://doi.org/10.4049/jimmunol.1002213
Published: 01 January 2011
View article titled, Hypoxia Selectively Inhibits Respiratory Burst Activity and Killing of Staphylococcus aureus in Human Neutrophils
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Includes: Supplementary data
Journal Articles

Distinct Cell Death Programs in Monocytes Regulate Innate Responses Following Challenge with Common Causes of Invasive Bacterial Disease

Steve J. Webster, Marc Daigneault, Martin A. Bewley, Julie A. Preston, Helen. M. Marriott, Sarah R. Walmsley, Robert C. Read, Moira K. B. Whyte, David H. Dockrell
Journal: The Journal of Immunology
J Immunol (2010) 185 (5): 2968–2979.
DOI: https://doi.org/10.4049/jimmunol.1000805
Published: 01 September 2010
View article titled, Distinct Cell Death Programs in Monocytes Regulate Innate Responses Following Challenge with Common Causes of Invasive Bacterial Disease
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Includes: Supplementary data
Journal Articles

Subversion of a Lysosomal Pathway Regulating Neutrophil Apoptosis by a Major Bacterial Toxin, Pyocyanin

Lynne R. Prince, Stephen M. Bianchi, Kathryn M. Vaughan, Martin A. Bewley, Helen M. Marriott, Sarah R. Walmsley, Graham W. Taylor, David J. Buttle, Ian Sabroe, David H. Dockrell, Moira K. B. Whyte
Journal: The Journal of Immunology
J Immunol (2008) 180 (5): 3502–3511.
DOI: https://doi.org/10.4049/jimmunol.180.5.3502
Published: 01 March 2008
View article titled, Subversion of a Lysosomal Pathway Regulating Neutrophil Apoptosis by a Major Bacterial Toxin, Pyocyanin
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Journal Articles

Inhibition of Neutrophil Apoptosis by ATP Is Mediated by the P2Y11 Receptor

Kathryn R. Vaughan, Leanne Stokes, Lynne R. Prince, Helen M. Marriott, Sabine Meis, Matthias U. Kassack, Colin D. Bingle, Ian Sabroe, Annmarie Surprenant, Moira K. B. Whyte
Journal: The Journal of Immunology
J Immunol (2007) 179 (12): 8544–8553.
DOI: https://doi.org/10.4049/jimmunol.179.12.8544
Published: 15 December 2007
View article titled, Inhibition of Neutrophil Apoptosis by ATP Is Mediated by the P2Y<sub>11</sub> Receptor
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Journal Articles

Decreased Alveolar Macrophage Apoptosis Is Associated with Increased Pulmonary Inflammation in a Murine Model of Pneumococcal Pneumonia

Helen M. Marriott, Paul G. Hellewell, Simon S. Cross, Paul G. Ince, Moira K. B. Whyte, David H. Dockrell
Journal: The Journal of Immunology
J Immunol (2006) 177 (9): 6480–6488.
DOI: https://doi.org/10.4049/jimmunol.177.9.6480
Published: 01 November 2006
View article titled, Decreased Alveolar Macrophage Apoptosis Is Associated with Increased Pulmonary Inflammation in a Murine Model of Pneumococcal Pneumonia
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Journal Articles

Pyocyanin Production by Pseudomonas aeruginosa Induces Neutrophil Apoptosis and Impairs Neutrophil-Mediated Host Defenses In Vivo

Lucy Allen, David H. Dockrell, Theresa Pattery, Daniel G. Lee, Pierre Cornelis, Paul G. Hellewell, Moira K. B. Whyte
Journal: The Journal of Immunology
J Immunol (2005) 174 (6): 3643–3649.
DOI: https://doi.org/10.4049/jimmunol.174.6.3643
Published: 15 March 2005
View article titled, Pyocyanin Production by Pseudomonas aeruginosa Induces Neutrophil Apoptosis and Impairs Neutrophil-Mediated Host Defenses In Vivo
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Journal Articles

Toll-Like Receptor (TLR)2 and TLR4 Agonists Regulate CCR Expression in Human Monocytic Cells

Lisa C. Parker, Moira K. B. Whyte, Stefanie N. Vogel, Steven K. Dower, Ian Sabroe
Journal: The Journal of Immunology
J Immunol (2004) 172 (8): 4977–4986.
DOI: https://doi.org/10.4049/jimmunol.172.8.4977
Published: 15 April 2004
View article titled, Toll-Like Receptor (TLR)2 and TLR4 Agonists Regulate CCR Expression in Human Monocytic Cells
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Journal Articles

Alveolar Macrophage Apoptosis Contributes to Pneumococcal Clearance in a Resolving Model of Pulmonary Infection

David H. Dockrell, Helen M. Marriott, Lynne R. Prince, Victoria C. Ridger, Paul G. Ince, Paul G. Hellewell, Moira K. B. Whyte
Journal: The Journal of Immunology
J Immunol (2003) 171 (10): 5380–5388.
DOI: https://doi.org/10.4049/jimmunol.171.10.5380
Published: 15 November 2003
View article titled, Alveolar Macrophage Apoptosis Contributes to Pneumococcal Clearance in a Resolving Model of Pulmonary Infection
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Journal Articles

Toll-Like Receptors in Health and Disease: Complex Questions Remain

In Special Collection:
Brief Reviews
Ian Sabroe, Robert C. Read, Moira K. B. Whyte, David H. Dockrell, Stefanie N. Vogel, Steven K. Dower
Journal: The Journal of Immunology
J Immunol (2003) 171 (4): 1630–1635.
DOI: https://doi.org/10.4049/jimmunol.171.4.1630
Published: 15 August 2003
View article titled, Toll-Like Receptors in Health and Disease: Complex Questions Remain
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Journal Articles

Selective Roles for Toll-Like Receptor (TLR)2 and TLR4 in the Regulation of Neutrophil Activation and Life Span

Ian Sabroe, Lynne R. Prince, Elizabeth C. Jones, Malcolm J. Horsburgh, Simon J. Foster, Stefanie N. Vogel, Steven K. Dower, Moira K. B. Whyte
Journal: The Journal of Immunology
J Immunol (2003) 170 (10): 5268–5275.
DOI: https://doi.org/10.4049/jimmunol.170.10.5268
Published: 15 May 2003
View article titled, Selective Roles for Toll-Like Receptor (TLR)2 and TLR4 in the Regulation of Neutrophil Activation and Life Span
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Journal Articles

Acceleration of Human Neutrophil Apoptosis by TRAIL

Stephen A. Renshaw, Jasvir S. Parmar, Vanessa Singleton, Sarah J. Rowe, David H. Dockrell, Steven K. Dower, Colin D. Bingle, Edwin R. Chilvers, Moira K. B. Whyte
Journal: The Journal of Immunology
J Immunol (2003) 170 (2): 1027–1033.
DOI: https://doi.org/10.4049/jimmunol.170.2.1027
Published: 15 January 2003
View article titled, Acceleration of Human Neutrophil Apoptosis by TRAIL
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Journal Articles

Caspase-1-Deficient Mice Have Delayed Neutrophil Apoptosis and a Prolonged Inflammatory Response to Lipopolysaccharide-Induced Acute Lung Injury

Sarah J. Rowe, Lucy Allen, Victoria C. Ridger, Paul G. Hellewell, Moira K. B. Whyte
Journal: The Journal of Immunology
J Immunol (2002) 169 (11): 6401–6407.
DOI: https://doi.org/10.4049/jimmunol.169.11.6401
Published: 01 December 2002
View article titled, Caspase-1-Deficient Mice Have Delayed Neutrophil Apoptosis and a Prolonged Inflammatory Response to Lipopolysaccharide-Induced Acute Lung Injury
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Journal Articles

Toll-Like Receptor (TLR)2 and TLR4 in Human Peripheral Blood Granulocytes: A Critical Role for Monocytes in Leukocyte Lipopolysaccharide Responses

Ian Sabroe, Elizabeth C. Jones, Lynne R. Usher, Moira K. B. Whyte, Steven K. Dower
Journal: The Journal of Immunology
J Immunol (2002) 168 (9): 4701–4710.
DOI: https://doi.org/10.4049/jimmunol.168.9.4701
Published: 01 May 2002
View article titled, Toll-Like Receptor (TLR)2 and TLR4 in Human Peripheral Blood Granulocytes: A Critical Role for Monocytes in Leukocyte Lipopolysaccharide Responses
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Journal Articles

Induction of Neutrophil Apoptosis by the Pseudomonas aeruginosa Exotoxin Pyocyanin: A Potential Mechanism of Persistent Infection

Lynne R. Usher, Roderick A. Lawson, Ian Geary, Christopher J. Taylor, Colin D. Bingle, Graham W. Taylor, Moira K. B. Whyte
Journal: The Journal of Immunology
J Immunol (2002) 168 (4): 1861–1868.
DOI: https://doi.org/10.4049/jimmunol.168.4.1861
Published: 15 February 2002
View article titled, Induction of Neutrophil Apoptosis by the Pseudomonas aeruginosa Exotoxin Pyocyanin: A Potential Mechanism of Persistent Infection
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