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N L Letvin
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Journal Articles

HIV-1 envelope-specific CD4+ T helper cells from simian/human immunodeficiency virus-infected rhesus monkeys recognize epitopes restricted by MHC class II DRB1*0406 and DRB*W201 molecules.

C Lekutis, N L Letvin
Journal: The Journal of Immunology
J Immunol (1997) 159 (4): 2049–2057.
DOI: https://doi.org/10.4049/jimmunol.159.4.2049
Published: 15 August 1997
View article titled, HIV-1 envelope-specific CD4+ T helper cells from simian/human immunodeficiency virus-infected rhesus monkeys recognize epitopes restricted by MHC class II DRB1*0406 and DRB*W201 molecules.
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Journal Articles

HIV-1 env DNA vaccine administered to rhesus monkeys elicits MHC class II-restricted CD4+ T helper cells that secrete IFN-gamma and TNF-alpha.

C Lekutis, J W Shiver, M A Liu, N L Letvin
Journal: The Journal of Immunology
J Immunol (1997) 158 (9): 4471–4477.
DOI: https://doi.org/10.4049/jimmunol.158.9.4471
Published: 01 May 1997
View article titled, HIV-1 env DNA vaccine administered to rhesus monkeys elicits MHC class II-restricted CD4+ T helper cells that secrete IFN-gamma and TNF-alpha.
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Journal Articles

IL-15 stimulates the expansion of AIDS virus-specific CTL.

T Kanai, E K Thomas, Y Yasutomi, N L Letvin
Journal: The Journal of Immunology
J Immunol (1996) 157 (8): 3681–3687.
DOI: https://doi.org/10.4049/jimmunol.157.8.3681
Published: 15 October 1996
View article titled, IL-15 stimulates the expansion of AIDS virus-specific CTL.
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Journal Articles

The T cell receptor gene usage by simian immunodeficiency virus gag-specific cytotoxic T lymphocytes in rhesus monkeys.

Z W Chen, L Shen, J D Regan, Z Kou, S H Ghim, N L Letvin
Journal: The Journal of Immunology
J Immunol (1996) 156 (4): 1469–1475.
DOI: https://doi.org/10.4049/jimmunol.156.4.1469
Published: 15 February 1996
View article titled, The T cell receptor gene usage by simian immunodeficiency virus gag-specific cytotoxic T lymphocytes in rhesus monkeys.
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Journal Articles

A MHC class I B locus allele-restricted simian immunodeficiency virus envelope CTL epitope in rhesus monkeys.

Y Yasutomi, S N McAdam, J E Boyson, M S Piekarczyk, D I Watkins, N L Letvin
Journal: The Journal of Immunology
J Immunol (1995) 154 (5): 2516–2522.
DOI: https://doi.org/10.4049/jimmunol.154.5.2516
Published: 01 March 1995
View article titled, A MHC class I B locus allele-restricted simian immunodeficiency virus envelope CTL epitope in rhesus monkeys.
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Journal Articles

The repertoire of cytotoxic T lymphocytes in the recognition of mutant simian immunodeficiency virus variants.

L Shen, Z W Chen, N L Letvin
Journal: The Journal of Immunology
J Immunol (1994) 153 (12): 5849–5854.
DOI: https://doi.org/10.4049/jimmunol.153.12.5849
Published: 15 December 1994
View article titled, The repertoire of cytotoxic T lymphocytes in the recognition of mutant simian immunodeficiency virus variants.
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Journal Articles

Synthetic peptide in mineral oil adjuvant elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes in rhesus monkeys.

Y Yasutomi, T J Palker, M B Gardner, B F Haynes, N L Letvin
Journal: The Journal of Immunology
J Immunol (1993) 151 (9): 5096–5105.
DOI: https://doi.org/10.4049/jimmunol.151.9.5096
Published: 01 November 1993
View article titled, Synthetic peptide in mineral oil adjuvant elicits simian immunodeficiency virus-specific CD8+ cytotoxic T lymphocytes in rhesus monkeys.
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Journal Articles

Conserved T-cell receptor repertoire in simian immunodeficiency virus-infected rhesus monkeys.

Z W Chen, Z C Kou, L Shen, K A Reimann, N L Letvin
Journal: The Journal of Immunology
J Immunol (1993) 151 (4): 2177–2187.
DOI: https://doi.org/10.4049/jimmunol.151.4.2177
Published: 15 August 1993
View article titled, Conserved T-cell receptor repertoire in simian immunodeficiency virus-infected rhesus monkeys.
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Journal Articles

Immunization with recombinant BCG-SIV elicits SIV-specific cytotoxic T lymphocytes in rhesus monkeys.

Y Yasutomi, S Koenig, S S Haun, C K Stover, R K Jackson, P Conard, A J Conley, E A Emini, T R Fuerst, N L Letvin
Journal: The Journal of Immunology
J Immunol (1993) 150 (7): 3101–3107.
DOI: https://doi.org/10.4049/jimmunol.150.7.3101
Published: 01 April 1993
View article titled, Immunization with recombinant BCG-SIV elicits SIV-specific cytotoxic T lymphocytes in rhesus monkeys.
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Journal Articles

Cytotoxic T lymphocytes do not appear to select for mutations in an immunodominant epitope of simian immunodeficiency virus gag.

Z W Chen, L Shen, M D Miller, S H Ghim, A L Hughes, N L Letvin
Journal: The Journal of Immunology
J Immunol (1992) 149 (12): 4060–4066.
DOI: https://doi.org/10.4049/jimmunol.149.12.4060
Published: 15 December 1992
View article titled, Cytotoxic T lymphocytes do not appear to select for mutations in an immunodominant epitope of simian immunodeficiency virus gag.
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Journal Articles

Simian immunodeficiency virus-specific cytotoxic T lymphocytes are present in the AIDS-associated skin rash in rhesus monkeys.

H Yamamoto, D J Ringler, M D Miller, Y Yasutomi, T Hasunuma, N L Letvin
Journal: The Journal of Immunology
J Immunol (1992) 149 (2): 728–734.
DOI: https://doi.org/10.4049/jimmunol.149.2.728
Published: 15 July 1992
View article titled, Simian immunodeficiency virus-specific cytotoxic T lymphocytes are present in the AIDS-associated skin rash in rhesus monkeys.
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Journal Articles

Molecular cloning of orangutan and gibbon MHC class I cDNA. The HLA-A and -B loci diverged over 30 million years ago.

Z W Chen, S N McAdam, A L Hughes, A L Dogon, N L Letvin, D I Watkins
Journal: The Journal of Immunology
J Immunol (1992) 148 (8): 2547–2554.
DOI: https://doi.org/10.4049/jimmunol.148.8.2547
Published: 15 April 1992
View article titled, Molecular cloning of orangutan and gibbon MHC class I cDNA. The HLA-A and -B loci diverged over 30 million years ago.
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Journal Articles

Regions of the CD4 molecule not involved in virus binding or syncytia formation are required for HIV-1 infection of lymphocytes.

T Hasunuma, H Tsubota, M Watanabe, Z W Chen, C I Lord, L C Burkly, J F Daley, N L Letvin
Journal: The Journal of Immunology
J Immunol (1992) 148 (6): 1841–1846.
DOI: https://doi.org/10.4049/jimmunol.148.6.1841
Published: 15 March 1992
View article titled, Regions of the CD4 molecule not involved in virus binding or syncytia formation are required for HIV-1 infection of lymphocytes.
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Journal Articles

Definition of an epitope and MHC class I molecule recognized by gag-specific cytotoxic T lymphocytes in SIVmac-infected rhesus monkeys.

M D Miller, H Yamamoto, A L Hughes, D I Watkins, N L Letvin
Journal: The Journal of Immunology
J Immunol (1991) 147 (1): 320–329.
DOI: https://doi.org/10.4049/jimmunol.147.1.320
Published: 01 July 1991
View article titled, Definition of an epitope and MHC class I molecule recognized by gag-specific cytotoxic T lymphocytes in SIVmac-infected rhesus monkeys.
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Journal Articles

Development of a monoclonal antibody, anti-6C2, which is involved in the interaction of CD4 T helper cells and activated B cells.

Y Torimoto, K Sugita, D S Weinberg, N H Dang, C Donahue, N L Letvin, S F Schlossman, C Morimoto
Journal: The Journal of Immunology
J Immunol (1991) 146 (7): 2176–2184.
DOI: https://doi.org/10.4049/jimmunol.146.7.2176
Published: 01 April 1991
View article titled, Development of a monoclonal antibody, anti-6C2, which is involved in the interaction of CD4 T helper cells and activated B cells.
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Journal Articles

Two distinct lymphocyte populations mediate simian immunodeficiency virus envelope-specific target cell lysis.

H Yamamoto, M D Miller, D I Watkins, G B Snyder, N E Chase, G P Mazzara, L Gritz, D L Panicali, N L Letvin
Journal: The Journal of Immunology
J Immunol (1990) 145 (11): 3740–3746.
DOI: https://doi.org/10.4049/jimmunol.145.11.3740
Published: 01 December 1990
View article titled, Two distinct lymphocyte populations mediate simian immunodeficiency virus envelope-specific target cell lysis.
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Journal Articles

Syrian hamsters express diverse MHC class I gene products.

D I Watkins, Z W Chen, A L Hughes, A Lagos, A M Lewis, Jr, J A Shadduck, N L Letvin
Journal: The Journal of Immunology
J Immunol (1990) 145 (10): 3483–3490.
DOI: https://doi.org/10.4049/jimmunol.145.10.3483
Published: 15 November 1990
View article titled, Syrian hamsters express diverse MHC class I gene products.
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Journal Articles

Genetically distinct cell populations in naturally occurring bone marrow-chimeric primates express similar MHC class I gene products.

D I Watkins, Z W Chen, A L Hughes, F S Hodi, N L Letvin
Journal: The Journal of Immunology
J Immunol (1990) 144 (10): 3726–3735.
DOI: https://doi.org/10.4049/jimmunol.144.10.3726
Published: 15 May 1990
View article titled, Genetically distinct cell populations in naturally occurring bone marrow-chimeric primates express similar MHC class I gene products.
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Journal Articles

Studies of cloned simian immunodeficiency virus-specific T lymphocytes. gag-specific cytotoxic T lymphocytes exhibit a restricted epitope specificity.

H Yamamoto, M D Miller, H Tsubota, D I Watkins, G P Mazzara, V Stallard, D L Panicali, A Aldovini, R A Young, N L Letvin
Journal: The Journal of Immunology
J Immunol (1990) 144 (9): 3385–3391.
DOI: https://doi.org/10.4049/jimmunol.144.9.3385
Published: 01 May 1990
View article titled, Studies of cloned simian immunodeficiency virus-specific T lymphocytes. gag-specific cytotoxic T lymphocytes exhibit a restricted epitope specificity.
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Molecular cloning of cDNA that encode MHC class I molecules from a New World primate (Saguinus oedipus). Natural selection acts at positions that may affect peptide presentation to T cells.

D I Watkins, N L Letvin, A L Hughes, T F Tedder
Journal: The Journal of Immunology
J Immunol (1990) 144 (3): 1136–1143.
DOI: https://doi.org/10.4049/jimmunol.144.3.1136
Published: 01 February 1990
View article titled, Molecular cloning of cDNA that encode MHC class I molecules from a New World primate (Saguinus oedipus). Natural selection acts at positions that may affect peptide presentation to T cells.
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