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Nicolas Legrand
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Journal Articles

Stem Cell Factor Consistently Improves Thymopoiesis after Experimental Transplantation of Murine or Human Hematopoietic Stem Cells in Immunodeficient Mice

Evert-Jan Wils, Elwin J. C. Rombouts, Irene van Mourik, Hergen Spits, Nicolas Legrand, Eric Braakman, Jan J. Cornelissen
Journal: The Journal of Immunology
J Immunol (2011) 187 (6): 2974–2981.
https://doi.org/10.4049/jimmunol.1004209
Published: 15 September 2011
View article titled, Stem Cell Factor Consistently Improves Thymopoiesis after Experimental Transplantation of Murine or Human Hematopoietic Stem Cells in Immunodeficient Mice
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Includes: Supplementary data
Journal Articles

IL-7 Enhances Thymic Human T Cell Development in “Human Immune System” Rag2−/−IL-2Rγc−/− Mice without Affecting Peripheral T Cell Homeostasis

Anja U. van Lent, Wendy Dontje, Maho Nagasawa, Rachida Siamari, Arjen Q. Bakker, Stephan M. Pouw, Kelly A. Maijoor, Kees Weijer, Jan J. Cornelissen, Bianca Blom, James P. Di Santo, Hergen Spits, Nicolas Legrand
Journal: The Journal of Immunology
J Immunol (2009) 183 (12): 7645–7655.
https://doi.org/10.4049/jimmunol.0902019
Published: 15 December 2009
View article titled, IL-7 Enhances Thymic Human T Cell Development in “Human Immune System” Rag2<sup>−/−</sup>IL-2Rγ<sub>c</sub><sup>−/−</sup> Mice without Affecting Peripheral T Cell Homeostasis
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Includes: Supplementary data
Journal Articles

Functional Human Antigen-Specific T Cells Produced In Vitro Using Retroviral T Cell Receptor Transfer into Hematopoietic Progenitors

Anja U. van Lent, Maho Nagasawa, Marleen M. van Loenen, Remko Schotte, Ton N. M. Schumacher, Mirjam H. M. Heemskerk, Hergen Spits, Nicolas Legrand
Journal: The Journal of Immunology
J Immunol (2007) 179 (8): 4959–4968.
https://doi.org/10.4049/jimmunol.179.8.4959
Published: 15 October 2007
View article titled, Functional Human Antigen-Specific T Cells Produced In Vitro Using Retroviral T Cell Receptor Transfer into Hematopoietic Progenitors
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Journal Articles

Experimental Models to Study Development and Function of the Human Immune System In Vivo

In Special Collection:
Brief Reviews
Nicolas Legrand, Kees Weijer, Hergen Spits
Journal: The Journal of Immunology
J Immunol (2006) 176 (4): 2053–2058.
https://doi.org/10.4049/jimmunol.176.4.2053
Published: 15 February 2006
View article titled, Experimental Models to Study Development and Function of the Human Immune System In Vivo
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Journal Articles

In Vivo and in Absence of a Thymus, the Enforced Expression of the Notch Ligands Delta-1 or Delta-4 Promotes T Cell Development with Specific Unique Effects

Alix de La Coste, Emmanuelle Six, Nicolas Fazilleau, Laurent Mascarell, Nicolas Legrand, Marie-Pierre Mailhé, Ana Cumano, Yacine Laâbi, Antonio A. Freitas
Journal: The Journal of Immunology
J Immunol (2005) 174 (5): 2730–2737.
https://doi.org/10.4049/jimmunol.174.5.2730
Published: 01 March 2005
View article titled, In Vivo and in Absence of a Thymus, the Enforced Expression of the Notch Ligands Delta-1 or Delta-4 Promotes T Cell Development with Specific Unique Effects
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Journal Articles

Homeostasis of Peripheral CD4+ T Cells: IL-2Rα and IL-2 Shape a Population of Regulatory Cells That Controls CD4+ T Cell Numbers

Afonso R. M. Almeida, Nicolas Legrand, Martine Papiernik, António A. Freitas
Journal: The Journal of Immunology
J Immunol (2002) 169 (9): 4850–4860.
https://doi.org/10.4049/jimmunol.169.9.4850
Published: 01 November 2002
View article titled, Homeostasis of Peripheral CD4<sup>+</sup> T Cells: IL-2Rα and IL-2 Shape a Population of Regulatory Cells That Controls CD4<sup>+</sup> T Cell Numbers
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Journal Articles

CD8+ T Lymphocytes in Double αβ TCR Transgenic Mice. I. TCR Expression and Thymus Selection in the Absence or in the Presence of Self-Antigen

Nicolas Legrand, Antonio A. Freitas
Journal: The Journal of Immunology
J Immunol (2001) 167 (11): 6150–6157.
https://doi.org/10.4049/jimmunol.167.11.6150
Published: 01 December 2001
View article titled, CD8<sup>+</sup> T Lymphocytes in Double αβ TCR Transgenic Mice. I. TCR Expression and Thymus Selection in the Absence or in the Presence of Self-Antigen
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Journal Articles

CD8+ T Lymphocytes in Double αβ TCR Transgenic Mice. II. Competitive Fitness of Dual αβ TCR CD8+ T Lymphocytes in the Peripheral Pools

Nicolas Legrand, Antonio A. Freitas
Journal: The Journal of Immunology
J Immunol (2001) 167 (11): 6158–6164.
https://doi.org/10.4049/jimmunol.167.11.6158
Published: 01 December 2001
View article titled, CD8<sup>+</sup> T Lymphocytes in Double αβ TCR Transgenic Mice. II. Competitive Fitness of Dual αβ TCR CD8<sup>+</sup> T Lymphocytes in the Peripheral Pools
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