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Journal Articles

JNK Regulatory Molecule G5PR Induces IgG Autoantibody–Producing Plasmablasts from Peritoneal B1a Cells

Masahiro Kitabatake, Miho Soma, Tianli Zhang, Kazuhiko Kuwahara, Yoshimi Fukushima, Takuya Nojima, Daisuke Kitamura, Nobuo Sakaguchi
Journal: The Journal of Immunology
J Immunol (2015) 194 (4): 1480–1488.
https://doi.org/10.4049/jimmunol.1401127
Published: 15 February 2015
View articletitled, JNK Regulatory Molecule G5PR Induces IgG Autoantibody–Producing Plasmablasts from Peritoneal B1a Cells
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Includes: Supplementary data
Journal Articles

NF-κB–Inducing Kinase in Thymic Stroma Establishes Central Tolerance by Orchestrating Cross-Talk with Not Only Thymocytes but Also Dendritic Cells

Yasuhiro Mouri, Hitoshi Nishijima, Hiroshi Kawano, Fumiko Hirota, Nobuo Sakaguchi, Junko Morimoto, Mitsuru Matsumoto
Journal: The Journal of Immunology
J Immunol (2014) 193 (9): 4356–4367.
https://doi.org/10.4049/jimmunol.1400389
Published: 01 November 2014
View articletitled, NF-κB–Inducing Kinase in Thymic Stroma Establishes Central Tolerance by Orchestrating Cross-Talk with Not Only Thymocytes but Also Dendritic Cells
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Includes: Supplementary data
Journal Articles

GANP Regulates the Choice of DNA Repair Pathway by DNA-PKcs Interaction in AID-Dependent IgV Region Diversification

Mohammed Mansour Abbas Eid, Kazuhiko Maeda, Sarah Ameen Almofty, Shailendra Kumar Singh, Mayuko Shimoda, Nobuo Sakaguchi
Journal: The Journal of Immunology
J Immunol (2014) 192 (12): 5529–5539.
https://doi.org/10.4049/jimmunol.1400021
Published: 15 June 2014
View articletitled, GANP Regulates the Choice of DNA Repair Pathway by DNA-PKcs Interaction in AID-Dependent IgV Region Diversification
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Includes: Supplementary data
Journal Articles

Molecular mechanism of transcription and epigenetic alteration at immunoglobulin variable gene heavy chain locus induced by GANP (IRM11P.761)

Shailendra Singh, Kazuhiko Maeda, Mohammed Eid, Sarah Almofty, Mayuko Shimoda, Teruya Kawabata, Nobuo Sakaguchi
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 130.3.
https://doi.org/10.4049/jimmunol.192.Supp.130.3
Published: 01 May 2014
View articletitled, Molecular mechanism of transcription and epigenetic alteration at immunoglobulin variable gene heavy chain locus induced by GANP (IRM11P.761)
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Journal Articles

GANP Interacts with APOBEC3G and Facilitates Its Encapsidation into the Virions To Reduce HIV-1 Infectivity

Kazuhiko Maeda, Sarah Ameen Almofty, Shailendra Kumar Singh, Mohammed Mansour Abbas Eid, Mayuko Shimoda, Terumasa Ikeda, Atsushi Koito, Phuong Pham, Myron F. Goodman, Nobuo Sakaguchi
Journal: The Journal of Immunology
J Immunol (2013) 191 (12): 6030–6039.
https://doi.org/10.4049/jimmunol.1302057
Published: 15 December 2013
View articletitled, GANP Interacts with APOBEC3G and Facilitates Its Encapsidation into the Virions To Reduce HIV-1 Infectivity
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Includes: Supplementary data
Journal Articles

Lyn Signaling To Upregulate GANP Is Critical for the Survival of High-Affinity B Cells in Germinal Centers of Lymphoid Organs

Kazuhiko Kuwahara, Teruo Nakaya, Suchada Phimsen, Teppei Toda, Masahiro Kitabatake, Tomohiro Kaji, Toshitada Takemori, Takeshi Watanabe, Nobuo Sakaguchi
Journal: The Journal of Immunology
J Immunol (2012) 189 (7): 3472–3479.
https://doi.org/10.4049/jimmunol.1200649
Published: 01 October 2012
View articletitled, Lyn Signaling To Upregulate GANP Is Critical for the Survival of High-Affinity B Cells in Germinal Centers of Lymphoid Organs
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Includes: Supplementary data
Journal Articles

Transgenic Overexpression of G5PR That Is Normally Augmented in Centrocytes Impairs the Enrichment of High-Affinity Antigen-Specific B Cells, Increases Peritoneal B-1a Cells, and Induces Autoimmunity in Aged Female Mice

Masahiro Kitabatake, Teppei Toda, Kazuhiko Kuwahara, Hideya Igarashi, Mareki Ohtsuji, Hiromichi Tsurui, Sachiko Hirose, Nobuo Sakaguchi
Journal: The Journal of Immunology
J Immunol (2012) 189 (3): 1193–1201.
https://doi.org/10.4049/jimmunol.1102774
Published: 01 August 2012
View articletitled, Transgenic Overexpression of G5PR That Is Normally Augmented in Centrocytes Impairs the Enrichment of High-Affinity Antigen-Specific B Cells, Increases Peritoneal B-1a Cells, and Induces Autoimmunity in Aged Female Mice
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Includes: Supplementary data
Journal Articles

Critical Role of Pcid2 in B Cell Survival through the Regulation of MAD2 Expression

Teruo Nakaya, Kazuhiko Kuwahara, Kazutaka Ohta, Masahiro Kitabatake, Teppei Toda, Naoki Takeda, Tokio Tani, Eisaku Kondo, Nobuo Sakaguchi
Journal: The Journal of Immunology
J Immunol (2010) 185 (9): 5180–5187.
https://doi.org/10.4049/jimmunol.1002026
Published: 01 November 2010
View articletitled, Critical Role of Pcid2 in B Cell Survival through the Regulation of MAD2 Expression
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Includes: Supplementary data
Journal Articles

A Flt3- and Ras-Dependent Pathway Primes B Cell Development by Inducing a State of IL-7 Responsiveness

Lin-Xi Li, Christine A. Goetz, Casey D. S. Katerndahl, Nobuo Sakaguchi, Michael A. Farrar
Journal: The Journal of Immunology
J Immunol (2010) 184 (4): 1728–1736.
https://doi.org/10.4049/jimmunol.0903023
Published: 11 January 2010
View articletitled, A Flt3- and Ras-Dependent Pathway Primes B Cell Development by Inducing a State of IL-7 Responsiveness
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Journal Articles

Cutting Edge: Double-Stranded DNA Breaks in the IgV Region Gene Were Detected at Lower Frequency in Affinity-Maturation Impeded GANP−/− Mice

Yousuke Kawatani, Hideya Igarashi, Takeshi Matsui, Kazuhiko Kuwahara, Satoru Fujimura, Nobukazu Okamoto, Katsumasa Takagi, Nobuo Sakaguchi
Journal: The Journal of Immunology
J Immunol (2005) 175 (9): 5615–5618.
https://doi.org/10.4049/jimmunol.175.9.5615
Published: 01 November 2005
View articletitled, Cutting Edge: Double-Stranded DNA Breaks in the IgV Region Gene Were Detected at Lower Frequency in Affinity-Maturation Impeded GANP−/− Mice
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Journal Articles

Generation of High-Affinity Antibody against T Cell-Dependent Antigen in the Ganp Gene-Transgenic Mouse

Nobuo Sakaguchi, Tetsuya Kimura, Shuzo Matsushita, Satoru Fujimura, Junji Shibata, Masatake Araki, Tamami Sakamoto, Chiemi Minoda, Kazuhiko Kuwahara
Journal: The Journal of Immunology
J Immunol (2005) 174 (8): 4485–4494.
https://doi.org/10.4049/jimmunol.174.8.4485
Published: 15 April 2005
View articletitled, Generation of High-Affinity Antibody against T Cell-Dependent Antigen in the Ganp Gene-Transgenic Mouse
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Journal Articles

Microarray Analysis of Lyn-Deficient B Cells Reveals Germinal Center-Associated Nuclear Protein and Other Genes Associated with the Lymphoid Germinal Center

Zeljka Korade Mirnics, Eva Caudell, YanHua Gao, Kazuhiko Kuwahara, Nobuo Sakaguchi, Tomohiro Kurosaki, Joan Burnside, Károly Mirnics, Seth J. Corey
Journal: The Journal of Immunology
J Immunol (2004) 172 (7): 4133–4141.
https://doi.org/10.4049/jimmunol.172.7.4133
Published: 01 April 2004
View articletitled, Microarray Analysis of Lyn-Deficient B Cells Reveals Germinal Center-Associated Nuclear Protein and Other Genes Associated with the Lymphoid Germinal Center
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Journal Articles

IL-1 Enhances T Cell-Dependent Antibody Production Through Induction of CD40 Ligand and OX40 on T Cells

Susumu Nakae, Masahide Asano, Reiko Horai, Nobuo Sakaguchi, Yoichiro Iwakura
Journal: The Journal of Immunology
J Immunol (2001) 167 (1): 90–97.
https://doi.org/10.4049/jimmunol.167.1.90
Published: 01 July 2001
View articletitled, IL-1 Enhances T Cell-Dependent Antibody Production Through Induction of CD40 Ligand and OX40 on T Cells
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Journal Articles

Cutting Edge: Absence of Expression of RAG1 in Peritoneal B-1 Cells Detected by Knocking into RAG1 Locus with Green Fluorescent Protein Gene

Naomi Kuwata, Hideya Igarashi, Takafumi Ohmura, Shinichi Aizawa, Nobuo Sakaguchi
Journal: The Journal of Immunology
J Immunol (1999) 163 (12): 6355–6359.
https://doi.org/10.4049/jimmunol.163.12.6355
Published: 15 December 1999
View articletitled, Cutting Edge: Absence of Expression of RAG1 in Peritoneal B-1 Cells Detected by Knocking into RAG1 Locus with Green Fluorescent Protein Gene
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Journal Articles

Involvement of Anti-Ig-Activated Serine Protease in the Generation of Cytoplasmic Factor(s) that Are Responsible for the Transmission of Ig-Receptor-Mediated Signals

Tadamitsu Kishimoto, Hitoshi Kikutani, Yoshio Nishizawa, Nobuo Sakaguchi, Yuichi Yamamura
Journal: The Journal of Immunology
J Immunol (1979) 123 (4): 1504–1510.
https://doi.org/10.4049/jimmunol.123.4.1504
Published: 01 October 1979
View articletitled, Involvement of Anti-Ig-Activated Serine Protease in the Generation of Cytoplasmic Factor(s) that Are Responsible for the Transmission of Ig-Receptor-Mediated Signals
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