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Nora Sarvetnick
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Journal Articles

Inflammation and decreased immunoregulation characterize the leptin receptor deficient (db/db) mouse model of type II diabetes. (173.12)

Virginia Hardie, Matthew Wheeler, Robert Harms, Craig Boyer, Kevin Thiessen, Nick George, Natalie Targy, Kristina Lorenzo, David Mercer, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 173.12.
https://doi.org/10.4049/jimmunol.188.Supp.173.12
Published: 01 May 2012
View article titled, Inflammation and decreased immunoregulation characterize the leptin receptor deficient (db/db) mouse model of type II diabetes. (173.12)
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Journal Articles

B7-2 Regulates Survival, Phenotype, and Function of APCs

Deepak Yadav, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2007) 178 (10): 6236–6241.
https://doi.org/10.4049/jimmunol.178.10.6236
Published: 15 May 2007
View article titled, B7-2 Regulates Survival, Phenotype, and Function of APCs
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Journal Articles

The role of PD-1/PD-L and B7/CD28 pathways in modulating anti-islet immune responses (B94)

Deepak Yadav, Natasha Hill, Hideo Yagita, Miyuki Azuma, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): LB19–LB20.
https://doi.org/10.4049/jimmunol.178.Supp.B94
Published: 01 April 2007
View article titled, The role of PD-1/PD-L and B7/CD28 pathways in modulating anti-islet immune responses (B94)
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CD8+ T Cell Tolerance in Nonobese Diabetic Mice Is Restored by Insulin-Dependent Diabetes Resistance Alleles

Xavier Martinez, Huub T. C. Kreuwel, William L. Redmond, Rebecca Trenney, Kara Hunter, Hugh Rosen, Nora Sarvetnick, Linda S. Wicker, Linda A. Sherman
Journal: The Journal of Immunology
J Immunol (2005) 175 (3): 1677–1685.
https://doi.org/10.4049/jimmunol.175.3.1677
Published: 01 August 2005
View article titled, CD8<sup>+</sup> T Cell Tolerance in Nonobese Diabetic Mice Is Restored by Insulin-Dependent Diabetes Resistance Alleles
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Journal Articles

RNase L and Double-Stranded RNA-Dependent Protein Kinase Exert Complementary Roles in Islet Cell Defense during Coxsackievirus Infection

Malin Flodström-Tullberg, Monica Hultcrantz, Alexandr Stotland, Amy Maday, Devin Tsai, Cody Fine, Bryan Williams, Robert Silverman, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2005) 174 (3): 1171–1177.
https://doi.org/10.4049/jimmunol.174.3.1171
Published: 01 February 2005
View article titled, RNase L and Double-Stranded RNA-Dependent Protein Kinase Exert Complementary Roles in Islet Cell Defense during Coxsackievirus Infection
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Journal Articles

B7-2 (CD86) Controls the Priming of Autoreactive CD4 T Cell Response against Pancreatic Islets

Deepak Yadav, Valeria Judkowski, Malin Flodstrom-Tullberg, Lori Sterling, William L. Redmond, Linda Sherman, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2004) 173 (6): 3631–3639.
https://doi.org/10.4049/jimmunol.173.6.3631
Published: 15 September 2004
View article titled, B7-2 (CD86) Controls the Priming of Autoreactive CD4 T Cell Response against Pancreatic Islets
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Journal Articles

Up-Regulation of CD1d Expression Restores the Immunoregulatory Function of NKT Cells and Prevents Autoimmune Diabetes in Nonobese Diabetic Mice

Marika Falcone, Federica Facciotti, Nadia Ghidoli, Paolo Monti, Stefano Olivieri, Luca Zaccagnino, Ezio Bonifacio, Giulia Casorati, Francesca Sanvito, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2004) 172 (10): 5908–5916.
https://doi.org/10.4049/jimmunol.172.10.5908
Published: 15 May 2004
View article titled, Up-Regulation of CD1d Expression Restores the Immunoregulatory Function of NKT Cells and Prevents Autoimmune Diabetes in Nonobese Diabetic Mice
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Terminal Deoxynucleotidyltransferase Deficiency Decreases Autoimmune Disease in Diabetes-Prone Nonobese Diabetic Mice and Lupus-Prone MRL-Faslpr Mice

Ian F. Robey, Melissa Peterson, Marc S. Horwitz, Dwight H. Kono, Thomas Stratmann, Argyrios N. Theofilopoulos, Nora Sarvetnick, Luc Teyton, Ann J. Feeney
Journal: The Journal of Immunology
J Immunol (2004) 172 (7): 4624–4629.
https://doi.org/10.4049/jimmunol.172.7.4624
Published: 01 April 2004
View article titled, Terminal Deoxynucleotidyltransferase Deficiency Decreases Autoimmune Disease in Diabetes-Prone Nonobese Diabetic Mice and Lupus-Prone MRL-<em>Fas</em><sup><em>lpr</em></sup> Mice
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Journal Articles

Th1 and Th2 Pancreatic Inflammation Differentially Affects Homing of Islet-Reactive CD4 Cells in Nonobese Diabetic Mice

Natasha J. Hill, Kurt Van Gunst, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2003) 170 (4): 1649–1658.
https://doi.org/10.4049/jimmunol.170.4.1649
Published: 15 February 2003
View article titled, Th1 and Th2 Pancreatic Inflammation Differentially Affects Homing of Islet-Reactive CD4 Cells in Nonobese Diabetic Mice
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Journal Articles

Control of the Autoimmune Response by Type 2 Nitric Oxide Synthase

Fu-Dong Shi, Malin Flodström, Soon Ha Kim, Shyam Pakala, Mary Cleary, Hans-Gustaf Ljunggren, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2001) 167 (5): 3000–3006.
https://doi.org/10.4049/jimmunol.167.5.3000
Published: 01 September 2001
View article titled, Control of the Autoimmune Response by Type 2 Nitric Oxide Synthase
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Journal Articles

H-2D End Confers Dominant Protection from IL-10-Mediated Acceleration of Autoimmune Diabetes in the Nonobese Diabetic Mouse

Antonio La Cava, Balaji Balasa, Augusta Good, Kurt van Gunst, Nadja Jung, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2001) 167 (2): 1066–1071.
https://doi.org/10.4049/jimmunol.167.2.1066
Published: 15 July 2001
View article titled, H-2D End Confers Dominant Protection from IL-10-Mediated Acceleration of Autoimmune Diabetes in the Nonobese Diabetic Mouse
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Journal Articles

Identification of MHC Class II-Restricted Peptide Ligands, Including a Glutamic Acid Decarboxylase 65 Sequence, that Stimulate Diabetogenic T Cells from Transgenic BDC2.5 Nonobese Diabetic Mice

Valeria Judkowski, Clemencia Pinilla, Kim Schroder, Lee Tucker, Nora Sarvetnick, Darcy B. Wilson
Journal: The Journal of Immunology
J Immunol (2001) 166 (2): 908–917.
https://doi.org/10.4049/jimmunol.166.2.908
Published: 15 January 2001
View article titled, Identification of MHC Class II-Restricted Peptide Ligands, Including a Glutamic Acid Decarboxylase 65 Sequence, that Stimulate Diabetogenic T Cells from Transgenic BDC2.5 Nonobese Diabetic Mice
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Journal Articles

A Mechanism for IL-10-Mediated Diabetes in the Nonobese Diabetic (NOD) Mouse: ICAM-1 Deficiency Blocks Accelerated Diabetes

Balaji Balasa, Antonio La Cava, Kurt Van Gunst, Lorraine Mocnik, Deepika Balakrishna, Nancy Nguyen, Lee Tucker, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2000) 165 (12): 7330–7337.
https://doi.org/10.4049/jimmunol.165.12.7330
Published: 15 December 2000
View article titled, A Mechanism for IL-10-Mediated Diabetes in the Nonobese Diabetic (NOD) Mouse: ICAM-1 Deficiency Blocks Accelerated Diabetes
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Journal Articles

IL-18 Directs Autoreactive T Cells and Promotes Autodestruction in the Central Nervous System Via Induction of IFN-γ by NK Cells

Fu-Dong Shi, Kiyoshi Takeda, Shizuo Akira, Nora Sarvetnick, Hans-Gustaf Ljunggren
Journal: The Journal of Immunology
J Immunol (2000) 165 (6): 3099–3104.
https://doi.org/10.4049/jimmunol.165.6.3099
Published: 15 September 2000
View article titled, IL-18 Directs Autoreactive T Cells and Promotes Autodestruction in the Central Nervous System Via Induction of IFN-γ by NK Cells
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Islet-Specific Expression of IL-10 Promotes Diabetes in Nonobese Diabetic Mice Independent of Fas, Perforin, TNF Receptor-1, and TNF Receptor-2 Molecules

Balaji Balasa, Kurt Van Gunst, Nadja Jung, Deepika Balakrishna, Pere Santamaria, Toshiaki Hanafusa, Naoto Itoh, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (2000) 165 (5): 2841–2849.
https://doi.org/10.4049/jimmunol.165.5.2841
Published: 01 September 2000
View article titled, Islet-Specific Expression of IL-10 Promotes Diabetes in Nonobese Diabetic Mice Independent of Fas, Perforin, TNF Receptor-1, and TNF Receptor-2 Molecules
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Journal Articles

CD4+ CD45RB Low-Density Cells from Untreated Mice Prevent Acute Allograft Rejection

Joanna D. Davies, Eric O’Connor, DeShon Hall, Troy Krahl, Joseph Trotter, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (1999) 163 (10): 5353–5357.
https://doi.org/10.4049/jimmunol.163.10.5353
Published: 15 November 1999
View article titled, CD4<sup>+</sup> CD45RB Low-Density Cells from Untreated Mice Prevent Acute Allograft Rejection
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Journal Articles

Comparing the Relative Role of Perforin/Granzyme Versus Fas/Fas Ligand Cytotoxic Pathways in CD8+ T Cell-Mediated Insulin-Dependent Diabetes Mellitus

Huub T. C. Kreuwel, David J. Morgan, Troy Krahl, Alice Ko, Nora Sarvetnick, Linda A. Sherman
Journal: The Journal of Immunology
J Immunol (1999) 163 (8): 4335–4341.
https://doi.org/10.4049/jimmunol.163.8.4335
Published: 15 October 1999
View article titled, Comparing the Relative Role of Perforin/Granzyme Versus Fas/Fas Ligand Cytotoxic Pathways in CD8<sup>+</sup> T Cell-Mediated Insulin-Dependent Diabetes Mellitus
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Journal Articles

Pancreatic IL-4 Expression Results in Islet-Reactive Th2 Cells That Inhibit Diabetogenic Lymphocytes in the Nonobese Diabetic Mouse

W. Scott Gallichan, Balaji Balasa, Joanna D. Davies, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (1999) 163 (3): 1696–1703.
https://doi.org/10.4049/jimmunol.163.3.1696
Published: 01 August 1999
View article titled, Pancreatic IL-4 Expression Results in Islet-Reactive Th2 Cells That Inhibit Diabetogenic Lymphocytes in the Nonobese Diabetic Mouse
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Islet-Specific Th1, But Not Th2, Cells Secrete Multiple Chemokines and Promote Rapid Induction of Autoimmune Diabetes

Linda M. Bradley, Valérie C. Asensio, Li-Karine Schioetz, Judith Harbertson, Troy Krahl, Gail Patstone, Nigel Woolf, Iain L. Campbell, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (1999) 162 (5): 2511–2520.
https://doi.org/10.4049/jimmunol.162.5.2511
Published: 01 March 1999
View article titled, Islet-Specific Th1, But Not Th2, Cells Secrete Multiple Chemokines and Promote Rapid Induction of Autoimmune Diabetes
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Journal Articles

IL-10 Impacts Autoimmune Diabetes Via a CD8+ T Cell Pathway Circumventing the Requirement for CD4+ T and B Lymphocytes

Balaji Balasa, Joanna D. Davies, Jae Lee, Augusta Good, Brian T. Yeung, Nora Sarvetnick
Journal: The Journal of Immunology
J Immunol (1998) 161 (8): 4420–4427.
https://doi.org/10.4049/jimmunol.161.8.4420
Published: 15 October 1998
View article titled, IL-10 Impacts Autoimmune Diabetes Via a CD8<sup>+ </sup>T Cell Pathway Circumventing the Requirement for CD4<sup>+ </sup>T and B Lymphocytes
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