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Paolo Casali
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Journal Articles

The transcription factor RORa plays a major role in generation and maintenance of human and mouse memory B cells

Yulai Zhou, Yijiang Xu, Hong Zan, Justin Moroney, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2024) 212 (1_Supplement): 0186_5013.
https://doi.org/10.4049/jimmunol.212.supp.0186.5013
Published: 01 May 2024
View article titled, The transcription factor RORa plays a major role in generation and maintenance of human and mouse memory B cells
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Journal Articles

B cell Tet2 promotes maturation of antibody responses through active DNA demethylation and OGT-mediated histone O-glycosylation of Aicda and Prdm1 loci

Shili Li, Yibo Peng, Zhimin Yang, Xin Li, Hong Zan, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2024) 212 (1_Supplement): 0221_5454.
https://doi.org/10.4049/jimmunol.212.supp.0221.5454
Published: 01 May 2024
View article titled, B cell Tet2 promotes maturation of antibody responses through active DNA demethylation and OGT-mediated histone O-glycosylation of Aicda and Prdm1 loci
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Journal Articles

Retinoic acid promotes IgA antibody responses by boosting B cell TGF-β-induced germline Iα-Cα transcription, the expression of Smad3, Runx2, Tgfbr1 and Blimp-1-mediated plasma cell differentiation

Zhimin Yang, Shili LI, Yulai Zhou, Tariq Elhashim, Hong Zan, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2024) 212 (1_Supplement): 1261_5772.
https://doi.org/10.4049/jimmunol.212.supp.1261.5772
Published: 01 May 2024
View article titled, Retinoic acid promotes IgA antibody responses by boosting B cell TGF-β-induced germline Iα-Cα transcription, the expression of Smad3, Runx2, Tgfbr1 and Blimp-1-mediated plasma cell differentiation
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Journal Articles

Intrinsic B cell TLR-BCR linked coengagement induces class-switched, hypermutated, neutralizing antibody responses in absence of T cells

Carlos Eduardo Rivera, Yulai Zhou, Daniel P. Chupp, Hui Yan, Amanda D. Fisher, Raphael Simon, Hong Zan, Zhenming Xu, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 60.08.
https://doi.org/10.4049/jimmunol.210.Supp.60.08
Published: 01 May 2023
View article titled, Intrinsic B cell TLR-BCR linked coengagement induces class-switched, hypermutated, neutralizing antibody responses in absence of T cells
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Journal Articles

B cell Tet2 promotes maturation of the antibody response through active DNA demethylation and OGT-mediated histone glycosylation of Aicdaand Prdm1loci

Shili Li, Yibo Peng, Xin Li, Zhimin Yang, Hong Zan, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 149.10.
https://doi.org/10.4049/jimmunol.210.Supp.149.10
Published: 01 May 2023
View article titled, B cell Tet2 promotes maturation of the antibody response through active DNA demethylation and OGT-mediated histone glycosylation of <em>Aicda</em>and <em>Prdm1</em>loci
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Journal Articles

RORα plays an important role in generation and maintenance of memory B cells

Yijiang Xu, Justin Moroney, Yulai Zhou, Hong Zan, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 76.02.
https://doi.org/10.4049/jimmunol.210.Supp.76.02
Published: 01 May 2023
View article titled, RORα plays an important role in generation and maintenance of memory B cells
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Journal Articles

Intrinsic B cell TLR-BCR linked coengagement induces mature and protective antibody responses in the absence of T cells

Carlos Eduardo Rivera, Hui Yan, Amanda Dee Fisher, Daniel Phillip Chupp, Raphael Simon, Hong Zan, Zhenming Xu, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 53.07.
https://doi.org/10.4049/jimmunol.208.Supp.53.07
Published: 01 May 2022
View article titled, Intrinsic B cell TLR-BCR linked coengagement induces mature and protective antibody responses in the absence of T cells
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Journal Articles

Epigenetic Modulation of Class-switch DNA Recombination to IgA by miR- 146a through Downregulation of Smad2, Smad3 and Smad4

shili li, Grecia Morales, Cassidy C Daw, Daniel Phillip Chupp, Amanda Dee Fisher, Hong Zan, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 112.19.
https://doi.org/10.4049/jimmunol.208.Supp.112.19
Published: 01 May 2022
View article titled, Epigenetic Modulation of Class-switch DNA Recombination to IgA by miR- 146a through Downregulation of Smad2, Smad3 and Smad4
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Journal Articles

Rad52 mediates class-switch DNA recombination to IgD

Yijiang Xu, Hang Zhou, Ginell Post, Hong Zan, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 112.17.
https://doi.org/10.4049/jimmunol.208.Supp.112.17
Published: 01 May 2022
View article titled, Rad52 mediates class-switch DNA recombination to IgD
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Journal Articles

Intrinsic B cell TLR-BCR coengagement induces mature and protective antibody responses in the absence of T cells

Carlos Eduardo Rivera, Daniel P Chupp, Hui Yan, Maria J Fernandez, Hong Zan, Raphael Simon, Zhenming Xu, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 24.03.
https://doi.org/10.4049/jimmunol.206.Supp.24.03
Published: 01 May 2021
View article titled, Intrinsic B cell TLR-BCR coengagement induces mature and protective antibody responses in the absence of T cells
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Journal Articles

Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells

Paolo Casali, Justin B Moroney, Anusha Vasudev, Alexander Pertsemlidis, Hong Zan
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 63.13.
https://doi.org/10.4049/jimmunol.206.Supp.63.13
Published: 01 May 2021
View article titled, Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells
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Journal Articles

Epigenetic regulation of IgA class-switching by miR-146a through selective downregulation of Smad2, Smad3 and Smad4

Paolo Casali, Justin B Moroney, Cassidy Daw, Grecia Morales, Daniel P Chupp, Hong Zan
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 63.14.
https://doi.org/10.4049/jimmunol.206.Supp.63.14
Published: 01 May 2021
View article titled, Epigenetic regulation of IgA class-switching by miR-146a through selective downregulation of Smad2, Smad3 and Smad4
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Journal Articles

Correction: B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-κB Activation for Antibody Class-Switching

Hui Yan, Maria Fernandez, Jingwei Wang, Shuai Wu, Rui Wang, Zheng Lou, Justin B. Moroney, Carlos E. Rivera, Julia R. Taylor, Huoqun Gan, Hong Zan, Dmytro Kovalskyy, Dongfang Liu, Paolo Casali, Zhenming Xu
Journal: The Journal of Immunology
J Immunol (2020) 204 (11): 3058.
https://doi.org/10.4049/jimmunol.2000342
Published: 01 June 2020
View article titled, Correction: B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-κB Activation for Antibody Class-Switching
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Journal Articles

IL-27-producing B cells synergize with IFNγ to promote IgG2a and IgG1 antibody responses

Hui Yan, Rui Wang, Jingwei Wang, Shuai Wu, Maria Fernandez, Carlos Eduardo Rivera, Justin B Moroney, Xiaodong Li, Nu Zhang, Hong Zan, Xiangzhi Meng, Fushun Zhang, Ross Kedl, Booki Min, Christopher A Hunter, Yan Xiang, Paolo Casali, Zhenming Xu
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 59.20.
https://doi.org/10.4049/jimmunol.204.Supp.59.20
Published: 01 May 2020
View article titled, IL-27-producing B cells synergize with IFNγ to promote IgG2a and IgG1 antibody responses
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Journal Articles

A humanized mouse platform supporting in vivo maturation of human antibody responses

Daniel P Chupp, Ometeotl Acosta, Hong Zan, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 86.48.
https://doi.org/10.4049/jimmunol.204.Supp.86.48
Published: 01 May 2020
View article titled, A humanized mouse platform supporting <em>in vivo</em> maturation of human antibody responses
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Journal Articles

Induction of T cell-independent hypermutated and protective IgG and IgA antibody responses by engagement of TLR4 or TLR5 and BCR

Carlos Eduardo Rivera, Daniel P Chupp, Hui Yan, John Im, Maria Fernandez, Hong Zan, Zhenming Xu, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 71.11.
https://doi.org/10.4049/jimmunol.204.Supp.71.11
Published: 01 May 2020
View article titled, Induction of T cell-independent hypermutated and protective IgG and IgA antibody responses by engagement of TLR4 or TLR5 and BCR
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Journal Articles

Integrative characterization of the coding and non-coding transcriptome in human memory B cells

Justin B Moroney, Anusha Vasudev, Alexander Pertsemlidis, Hong Zan, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 155.4.
https://doi.org/10.4049/jimmunol.204.Supp.155.4
Published: 01 May 2020
View article titled, Integrative characterization of the coding and non-coding transcriptome in human memory B cells
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Journal Articles

B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-κB Activation for Antibody Class-Switching

Hui Yan, Maria Fernandez, Jingwei Wang, Shuai Wu, Rui Wang, Zheng Lou, Justin B. Moroney, Carlos E. Rivera, Julia R. Taylor, Huoqun Gan, Hong Zan, Dmytro Kovalskyy, Dongfang Liu, Paolo Casali, Zhenming Xu
Journal: The Journal of Immunology
J Immunol (2020) 204 (5): 1146–1157.
https://doi.org/10.4049/jimmunol.1901170
Published: 01 March 2020
View article titled, B Cell Endosomal RAB7 Promotes TRAF6 K63 Polyubiquitination and NF-κB Activation for Antibody Class-Switching
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Includes: Supplementary data
Journal Articles

Induction of T cell-independent hypermutated and protective IgG and IgA antibody responses by TLR4-BCR or TLR5-BCR co-engagement

Carlos Eduardo Rivera, Daniel Chupp, Hui Yan, IM John, Jingwei Wang, Helia Nasrollahi Sanchez, Shuai Wu, Julia Taylor, Hong Zan, Zhenming Xu, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 121.11.
https://doi.org/10.4049/jimmunol.202.Supp.121.11
Published: 01 May 2019
View article titled, Induction of T cell-independent hypermutated and protective IgG and IgA antibody responses by TLR4-BCR or TLR5-BCR co-engagement
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Journal Articles

Integrative analysis of human memory B cell coding and non-coding transcriptomes

Justin B Moroney, Anusha Vasudev, Julia R Taylor, Hong Zan, Alexander Pertsemlidis, Paolo Casali
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 123.14.
https://doi.org/10.4049/jimmunol.202.Supp.123.14
Published: 01 May 2019
View article titled, Integrative analysis of human memory B cell coding and non-coding transcriptomes
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