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Patricia Busto
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Journal Articles

Cross-Reactive Antigen Expressed by B6 Splenocytes Drives Receptor Editing and Marginal Zone Differentiation of IgG2a-Reactive AM14 Vκ8 B Cells

Kerstin Nündel, Purvi Mande, Stephanie L. Moses, Patricia Busto, Jaime L. Cullen, Madelyn R. Schmidt, Mark J. Shlomchik, Robert T. Woodland, Ann Marshak-Rothstein
Journal: The Journal of Immunology
J Immunol (2019) 203 (8): 2055–2062.
https://doi.org/10.4049/jimmunol.1900499
Published: 15 October 2019
View article titled, Cross-Reactive Antigen Expressed by B6 Splenocytes Drives Receptor Editing and Marginal Zone Differentiation of IgG2a-Reactive AM14 Vκ8 B Cells
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Journal Articles

Overexpression of Soluble Fas Ligand following Adeno-Associated Virus Gene Therapy Prevents Retinal Ganglion Cell Death in Chronic and Acute Murine Models of Glaucoma

Anitha Krishnan, Fei Fei, Alexander Jones, Patricia Busto, Ann Marshak-Rothstein, Bruce R. Ksander, Meredith Gregory-Ksander
Journal: The Journal of Immunology
J Immunol (2016) 197 (12): 4626–4638.
https://doi.org/10.4049/jimmunol.1601488
Published: 15 December 2016
View article titled, Overexpression of Soluble Fas Ligand following Adeno-Associated Virus Gene Therapy Prevents Retinal Ganglion Cell Death in Chronic and Acute Murine Models of Glaucoma
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Journal Articles

TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus

Lukas Bossaller, Anette Christ, Karin Pelka, Kerstin Nündel, Ping-I Chiang, Catherine Pang, Neha Mishra, Patricia Busto, Ramon G. Bonegio, Reinhold Ernst Schmidt, Eicke Latz, Ann Marshak-Rothstein
Journal: The Journal of Immunology
J Immunol (2016) 197 (4): 1044–1053.
https://doi.org/10.4049/jimmunol.1501943
Published: 15 August 2016
View article titled, TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus
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Includes: Supplementary data
Journal Articles

Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II−/−IFNaR−/− Mice

Rebecca Baum, Kerstin Nündel, Sudesh Pawaria, Shruti Sharma, Patricia Busto, Katherine A. Fitzgerald, Ellen M. Gravallese, Ann Marshak-Rothstein
Journal: The Journal of Immunology
J Immunol (2016) 196 (3): 1348–1354.
https://doi.org/10.4049/jimmunol.1502130
Published: 01 February 2016
View article titled, Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II<sup>−/−</sup>IFNaR<sup>−/−</sup> Mice
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Journal Articles

Cell-Intrinsic Expression of TLR9 in Autoreactive B Cells Constrains BCR/TLR7-Dependent Responses

Kerstin Nündel, Nathaniel M. Green, Arthur L. Shaffer, Krishna L. Moody, Patricia Busto, Dan Eilat, Kensuke Miyake, Michael A. Oropallo, Michael P. Cancro, Ann Marshak-Rothstein
Journal: The Journal of Immunology
J Immunol (2015) 194 (6): 2504–2512.
https://doi.org/10.4049/jimmunol.1402425
Published: 15 March 2015
View article titled, Cell-Intrinsic Expression of TLR9 in Autoreactive B Cells Constrains BCR/TLR7-Dependent Responses
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Includes: Supplementary data
Journal Articles

Cutting Edge: DNase II Deficiency Prevents Activation of Autoreactive B Cells by Double-Stranded DNA Endogenous Ligands

Sudesh Pawaria, Krishna Moody, Patricia Busto, Kerstin Nündel, Chee-Ho Choi, Tariq Ghayur, Ann Marshak-Rothstein
Journal: The Journal of Immunology
J Immunol (2015) 194 (4): 1403–1407.
https://doi.org/10.4049/jimmunol.1402893
Published: 15 February 2015
View article titled, Cutting Edge: DNase II Deficiency Prevents Activation of Autoreactive B Cells by Double-Stranded DNA Endogenous Ligands
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Journal Articles

Cutting Edge: AIM2 and Endosomal TLRs Differentially Regulate Arthritis and Autoantibody Production in DNase II–Deficient Mice

Rebecca Baum, Shruti Sharma, Susan Carpenter, Quan-Zhen Li, Patricia Busto, Katherine A. Fitzgerald, Ann Marshak-Rothstein, Ellen M. Gravallese
Journal: The Journal of Immunology
J Immunol (2015) 194 (3): 873–877.
https://doi.org/10.4049/jimmunol.1402573
Published: 01 February 2015
View article titled, Cutting Edge: AIM2 and Endosomal TLRs Differentially Regulate Arthritis and Autoantibody Production in DNase II–Deficient Mice
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Journal Articles

Overexpression of Membrane-Bound Fas Ligand (CD95L) Exacerbates Autoimmune Disease and Renal Pathology in Pristane-Induced Lupus

Lukas Bossaller, Vijay A. K. Rathinam, Ramon Bonegio, Ping-I Chiang, Patricia Busto, Adam R. Wespiser, Daniel R. Caffrey, Quan-Zhen Li, Chandra Mohan, Katherine A. Fitzgerald, Eicke Latz, Ann Marshak-Rothstein
Journal: The Journal of Immunology
J Immunol (2013) 191 (5): 2104–2114.
https://doi.org/10.4049/jimmunol.1300341
Published: 01 September 2013
View article titled, Overexpression of Membrane-Bound Fas Ligand (CD95L) Exacerbates Autoimmune Disease and Renal Pathology in Pristane-Induced Lupus
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Includes: Supplementary data
Journal Articles

IFN Regulatory Factor 5 Is Required for Disease Development in the FcγRIIB−/−Yaa and FcγRIIB−/− Mouse Models of Systemic Lupus Erythematosus

Christophe Richez, Kei Yasuda, Ramon G. Bonegio, Amanda A. Watkins, Tamar Aprahamian, Patricia Busto, Rocco J. Richards, Chih Long Liu, Regina Cheung, Paul J. Utz, Ann Marshak-Rothstein, Ian R. Rifkin
Journal: The Journal of Immunology
J Immunol (2010) 184 (2): 796–806.
https://doi.org/10.4049/jimmunol.0901748
Published: 27 December 2009
View article titled, IFN Regulatory Factor 5 Is Required for Disease Development in the <em>FcγRIIB<sup>−/−</sup>Yaa</em> and <em>FcγRIIB<sup>−/−</sup></em> Mouse Models of Systemic Lupus Erythematosus
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Journal Articles

Autoreactive B Cells Discriminate CpG-Rich and CpG-Poor DNA and This Response Is Modulated by IFN-α

Melissa B. Uccellini, Liliana Busconi, Nathaniel M. Green, Patricia Busto, Sean R. Christensen, Mark J. Shlomchik, Ann Marshak-Rothstein, Gregory A. Viglianti
Journal: The Journal of Immunology
J Immunol (2008) 181 (9): 5875–5884.
https://doi.org/10.4049/jimmunol.181.9.5875
Published: 01 November 2008
View article titled, Autoreactive B Cells Discriminate CpG-Rich and CpG-Poor DNA and This Response Is Modulated by IFN-α
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