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Philippe Guillaume
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Journal Articles

The Length Distribution and Multiple Specificity of Naturally Presented HLA-I Ligands

David Gfeller, Philippe Guillaume, Justine Michaux, Hui-Song Pak, Roy T. Daniel, Julien Racle, George Coukos, Michal Bassani-Sternberg
Journal: The Journal of Immunology
J Immunol (2018) 201 (12): 3705–3716.
https://doi.org/10.4049/jimmunol.1800914
Published: 15 December 2018
View article titled, The Length Distribution and Multiple Specificity of Naturally Presented HLA-I Ligands
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Includes: Supplementary data
Journal Articles

PD-1 and Tim-3 regulate the expansion of vaccine-induced tumor antigen-specific CD8+ T cells in patients with advanced melanoma (VAC3P.944)

Julien Fourcade, Zhaojun Sun, Ornella Pagliano, Joe-Marc Chauvin, Hong Wang, Cindy Sander, Bratislav Janjic, Ahmad Tarhini, Hussein Tawbi, John Kirkwood, Stergios Moschos, Philippe Guillaume, Immanuel Luescher, Arthur Krieg, Ana Anderson, Vijay Kuchroo, Hassane Zarour
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 73.6.
https://doi.org/10.4049/jimmunol.192.Supp.73.6
Published: 01 May 2014
View article titled, PD-1 and Tim-3 regulate the expansion of vaccine-induced tumor antigen-specific CD8+ T cells in patients with advanced melanoma (VAC3P.944)
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Journal Articles

The upregulation of the inhibitory receptors BTLA and PD-1 defines a novel subset of dysfunctional tumor antigen-specific CD8+ T cells (127.19)

Julien Fourcade, Zhaojun Sun, Ornella Pagliano, Philippe Guillaume, Immanuel Luescher, Cindy Sander, John Kirkwood, Daniel Olive, Vijay Kuchroo, Hassane Zarour
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 127.19.
https://doi.org/10.4049/jimmunol.188.Supp.127.19
Published: 01 May 2012
View article titled, The upregulation of the inhibitory receptors BTLA and PD-1 defines a novel subset of dysfunctional tumor antigen-specific CD8+ T cells (127.19)
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Journal Articles

Interaction of the humoral immune system with peptides presented by class I major histocompatibility (MHC) complexes (42.4)

Gerhard Held, Immanuel Luescher, Frank Neumann, Martina Sester, Philippe Guillaume, Markus Hoth, Michael Pfreundschuh
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 42.4.
https://doi.org/10.4049/jimmunol.188.Supp.42.4
Published: 01 May 2012
View article titled, Interaction of the humoral immune system with peptides presented by class I major histocompatibility (MHC) complexes (42.4)
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Journal Articles

Targeting PD-1 and Tim-3 pathways to reverse tumor antigen-specific CD4+ T cell dysfunction in patients with advanced melanoma (66.1)

Julien Fourcade, Zhaojun Sun, Philippe Guillaume, Immanuel Luescher, Cindy Sander, John Kirkwood, Vijay Kuchroo, Hassane Zarour
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 66.1.
https://doi.org/10.4049/jimmunol.186.Supp.66.1
Published: 01 April 2011
View article titled, Targeting PD-1 and Tim-3 pathways to reverse tumor antigen-specific CD4+ T cell dysfunction in patients with advanced melanoma (66.1)
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Journal Articles

Peptide Vaccine Induces Enhanced Tumor Growth Associated with Apoptosis Induction in CD8+ T Cells

Daisuke Muraoka, Takuma Kato, Linan Wang, Yuka Maeda, Takuro Noguchi, Naozumi Harada, Kazuyoshi Takeda, Hideo Yagita, Philippe Guillaume, Immanuel Luescher, Lloyd J. Old, Hiroshi Shiku, Hiroyoshi Nishikawa
Journal: The Journal of Immunology
J Immunol (2010) 185 (6): 3768–3776.
https://doi.org/10.4049/jimmunol.0903649
Published: 15 September 2010
View article titled, Peptide Vaccine Induces Enhanced Tumor Growth Associated with Apoptosis Induction in CD8<sup>+</sup> T Cells
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Includes: Supplementary data
Journal Articles

PD-1 Is a Regulator of NY-ESO-1-Specific CD8+ T Cell Expansion in Melanoma Patients

Julien Fourcade, Pavol Kudela, Zhaojun Sun, Hongmei Shen, Stephanie R. Land, Diana Lenzner, Philippe Guillaume, Immanuel F. Luescher, Cindy Sander, Soldano Ferrone, John M. Kirkwood, Hassane M. Zarour
Journal: The Journal of Immunology
J Immunol (2009) 182 (9): 5240–5249.
https://doi.org/10.4049/jimmunol.0803245
Published: 01 May 2009
View article titled, PD-1 Is a Regulator of NY-ESO-1-Specific CD8<sup>+</sup> T Cell Expansion in Melanoma Patients
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Journal Articles

An Essential Role for the Stalk Region of CD8β in the Coreceptor Function of CD8

Lorna Rettig, Louise McNeill, Nitza Sarner, Philippe Guillaume, Immanuel Luescher, Mauro Tolaini, Dimitris Kioussis, Rose Zamoyska
Journal: The Journal of Immunology
J Immunol (2009) 182 (1): 121–129.
https://doi.org/10.4049/jimmunol.182.1.121
Published: 01 January 2009
View article titled, An Essential Role for the Stalk Region of CD8β in the Coreceptor Function of CD8
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Journal Articles

Molecular Design of the Cαβ Interface Favors Specific Pairing of Introduced TCRαβ in Human T Cells

Ralf-Holger Voss, Ralph A. Willemsen, Jürgen Kuball, Margarete Grabowski, Renate Engel, Ratna S. Intan, Philippe Guillaume, Pedro Romero, Christoph Huber, Matthias Theobald
Journal: The Journal of Immunology
J Immunol (2008) 180 (1): 391–401.
https://doi.org/10.4049/jimmunol.180.1.391
Published: 01 January 2008
View article titled, Molecular Design of the Cαβ Interface Favors Specific Pairing of Introduced TCRαβ in Human T Cells
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Journal Articles

IL-12 Controls Cytotoxicity of a Novel Subset of Self-Antigen-Specific Human CD28+ Cytolytic T Cells

Catherine Barbey, Petra Baumgaertner, Estelle Devevre, Verena Rubio-Godoy, Laurent Derre, Gabriel Bricard, Philippe Guillaume, Immanuel F. Luescher, Danielle Liénard, Jean-Charles Cerottini, Pedro Romero, Nathalie Rufer, Daniel E. Speiser
Journal: The Journal of Immunology
J Immunol (2007) 178 (6): 3566–3574.
https://doi.org/10.4049/jimmunol.178.6.3566
Published: 15 March 2007
View article titled, IL-12 Controls Cytotoxicity of a Novel Subset of Self-Antigen-Specific Human CD28<sup>+</sup> Cytolytic T Cells
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Journal Articles

Interactions of Ly49 Family Receptors with MHC Class I Ligands in trans and cis

Léonardo Scarpellino, Franziska Oeschger, Philippe Guillaume, Jérôme D. Coudert, Frédéric Lévy, Georges Leclercq, Werner Held
Journal: The Journal of Immunology
J Immunol (2007) 178 (3): 1277–1284.
https://doi.org/10.4049/jimmunol.178.3.1277
Published: 01 February 2007
View article titled, Interactions of Ly49 Family Receptors with MHC Class I Ligands in <em>trans</em> and <em>cis</em>
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Journal Articles

A Natural Structural Variant of the Mouse TCR β-Chain Displays Intrinsic Receptor Function and Antigen Specificity

Anne Aublin, Maria Ciofani, Nancy Willkomm, Abdelbasset Hamrouni, Andrea L. Szymczak-Workman, Tomio Takahashi, Yongoua Sandjeu, Philippe Guillaume, Dario A. A. Vignali, Olivier Michielin, Juan Carlos Zúñiga-Pflücker, Janet L. Maryanski
Journal: The Journal of Immunology
J Immunol (2006) 177 (12): 8587–8594.
https://doi.org/10.4049/jimmunol.177.12.8587
Published: 15 December 2006
View article titled, A Natural Structural Variant of the Mouse TCR β-Chain Displays Intrinsic Receptor Function and Antigen Specificity
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Journal Articles

Fluorescence-Activated Cell Sorting and Cloning of Bona Fide CD8+ CTL with Reversible MHC-Peptide and Antibody Fab′ Conjugates

Philippe Guillaume, Petra Baumgaertner, Georgi S. Angelov, Daniel Speiser, Immanuel F. Luescher
Journal: The Journal of Immunology
J Immunol (2006) 177 (6): 3903–3912.
https://doi.org/10.4049/jimmunol.177.6.3903
Published: 15 September 2006
View article titled, Fluorescence-Activated Cell Sorting and Cloning of Bona Fide CD8<sup>+</sup> CTL with Reversible MHC-Peptide and Antibody Fab′ Conjugates
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Journal Articles

TCR-α CDR3 Loop Audition Regulates Positive Selection

Cristina Ferreira, Anna Furmanski, Maggie Millrain, Istvan Bartok, Philippe Guillaume, Rosemary Lees, Elizabeth Simpson, H. Robson MacDonald, Julian Dyson
Journal: The Journal of Immunology
J Immunol (2006) 177 (4): 2477–2485.
https://doi.org/10.4049/jimmunol.177.4.2477
Published: 15 August 2006
View article titled, TCR-α CDR3 Loop Audition Regulates Positive Selection
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Journal Articles

New Generation Vaccine Induces Effective Melanoma-Specific CD8+ T Cells in the Circulation but Not in the Tumor Site

Victor Appay, Camilla Jandus, Verena Voelter, Severine Reynard, Sarah E. Coupland, Donata Rimoldi, Danielle Lienard, Philippe Guillaume, Arthur M. Krieg, Jean-Charles Cerottini, Pedro Romero, Serge Leyvraz, Nathalie Rufer, Daniel E. Speiser
Journal: The Journal of Immunology
J Immunol (2006) 177 (3): 1670–1678.
https://doi.org/10.4049/jimmunol.177.3.1670
Published: 01 August 2006
View article titled, New Generation Vaccine Induces Effective Melanoma-Specific CD8<sup>+</sup> T Cells in the Circulation but Not in the Tumor Site
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Journal Articles

Soluble MHC-Peptide Complexes Containing Long Rigid Linkers Abolish CTL-Mediated Cytotoxicity

Georgi S. Angelov, Philippe Guillaume, Marek Cebecauer, Giovanna Bosshard, Danijel Dojcinovic, Petra Baumgaertner, Immanuel F. Luescher
Journal: The Journal of Immunology
J Immunol (2006) 176 (6): 3356–3365.
https://doi.org/10.4049/jimmunol.176.6.3356
Published: 15 March 2006
View article titled, Soluble MHC-Peptide Complexes Containing Long Rigid Linkers Abolish CTL-Mediated Cytotoxicity
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Journal Articles

Ex Vivo Characterization of Allo-MHC-Restricted T Cells Specific for a Single MHC-Peptide Complex

Mikaël J. Pittet, Asma Gati, Frederic-Anne Le Gal, Gilles Bioley, Philippe Guillaume, Magda de Smedt, Jean Plum, Daniel E. Speiser, Jean-Charles Cerottini, Pierre-Yves Dietrich, Pedro Romero, Alfred Zippelius
Journal: The Journal of Immunology
J Immunol (2006) 176 (4): 2330–2336.
https://doi.org/10.4049/jimmunol.176.4.2330
Published: 15 February 2006
View article titled, Ex Vivo Characterization of Allo-MHC-Restricted T Cells Specific for a Single MHC-Peptide Complex
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Journal Articles

Soluble MHC-Peptide Complexes Induce Rapid Death of CD8+ CTL

Marek Cebecauer, Philippe Guillaume, Pavel Hozák, Silke Mark, Helen Everett, Pascal Schneider, Immanuel F. Luescher
Journal: The Journal of Immunology
J Immunol (2005) 174 (11): 6809–6819.
https://doi.org/10.4049/jimmunol.174.11.6809
Published: 01 June 2005
View article titled, Soluble MHC-Peptide Complexes Induce Rapid Death of CD8<sup>+</sup> CTL
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Journal Articles

α3 Domain Mutants of Peptide/MHC Class I Multimers Allow the Selective Isolation of High Avidity Tumor-Reactive CD8 T Cells

Mikaël J. Pittet, Verena Rubio-Godoy, Gilles Bioley, Philippe Guillaume, Pascal Batard, Daniel Speiser, Immanuel Luescher, Jean-Charles Cerottini, Pedro Romero, Alfred Zippelius
Journal: The Journal of Immunology
J Immunol (2003) 171 (4): 1844–1849.
https://doi.org/10.4049/jimmunol.171.4.1844
Published: 15 August 2003
View article titled, α3 Domain Mutants of Peptide/MHC Class I Multimers Allow the Selective Isolation of High Avidity Tumor-Reactive CD8 T Cells
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Journal Articles

Prevalent Role of TCR α-Chain in the Selection of the Preimmune Repertoire Specific for a Human Tumor-Associated Self-Antigen

Pierre-Yves Dietrich, Frédérique-Anne Le Gal, Valérie Dutoit, Mikäel J. Pittet, Lydie Trautman, Alfred Zippelius, Isabelle Cognet, Valérie Widmer, Paul R. Walker, Olivier Michielin, Philippe Guillaume, Thierry Connerotte, Francine Jotereau, Pierre G. Coulie, Pedro Romero, Jean-Charles Cerottini, Marc Bonneville, Danila Valmori
Journal: The Journal of Immunology
J Immunol (2003) 170 (10): 5103–5109.
https://doi.org/10.4049/jimmunol.170.10.5103
Published: 15 May 2003
View article titled, Prevalent Role of TCR α-Chain in the Selection of the Preimmune Repertoire Specific for a Human Tumor-Associated Self-Antigen
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