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Phyllis Silver
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Journal Articles

Nonredundant role for GM-CSF in autoimmune pathology of the neureretina in the absence of IFN-γ and IL-17A

So Jin Bing, Phyllis Silver, Yingyos Jittayasothorn, Reiko Horai, Rachel R Caspi
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 156.22.
https://doi.org/10.4049/jimmunol.198.Supp.156.22
Published: 01 May 2017
View article titled, Nonredundant role for GM-CSF in autoimmune pathology of the neureretina in the absence of IFN-γ and IL-17A
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Journal Articles

IL-17A inhibits expression of IL-17-lineage cytokines through a negative feedback loop involving IL-24 and controls autoimmune uveitis

Wai Po Chong, Kumarkrishna Raychaudhuri, Reiko Horai, Phyllis Silver, Yingyos Jittayasothorn, Chi-Chao Chan, Jun Chen, Rachel R Caspi
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 156.18.
https://doi.org/10.4049/jimmunol.198.Supp.156.18
Published: 01 May 2017
View article titled, IL-17A inhibits expression of IL-17-lineage cytokines through a negative feedback loop involving IL-24 and controls autoimmune uveitis
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Journal Articles

Vitamin A deficiency impacts acquisition, but not expression, of autoimmunity to the neuroretina

Reiko Horai, Ru Zhou, So Jin Bing, Kaska Wloka, Jun Chen, Phyllis Silver, Yingyos Jittayasothorn, Rachel R Caspi
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 218.8.
https://doi.org/10.4049/jimmunol.198.Supp.218.8
Published: 01 May 2017
View article titled, Vitamin A deficiency impacts acquisition, but not expression, of autoimmunity to the neuroretina
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Journal Articles

Microbiome-dependent modulation of mucosal immunity at the ocular surface.

Anthony J St. Leger, Jigar V Desai, Rebecca Drummond, Abirami Kugadas, Fatimah Almaghrabi, Phyllis Silver, Mihaela Gadjeva, Yoichiro Iwakura, Michail S Lionakis, Rachel R Caspi
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 149.6.
https://doi.org/10.4049/jimmunol.198.Supp.149.6
Published: 01 May 2017
View article titled, Microbiome-dependent modulation of mucosal immunity at the ocular surface.
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Journal Articles

Mincle activation and the Syk/Card9 signaling axis are central to development of autoimmune disease of the eye

Ellen Lee, Brieanna Brown, Paige Snow, Emily Vance, Phyllis Silver, Christine Wells, Rachel R Caspi, Holly L. Rosenzweig
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 48.17.
https://doi.org/10.4049/jimmunol.196.Supp.48.17
Published: 01 May 2016
View article titled, Mincle activation and the Syk/Card9 signaling axis are central to development of autoimmune disease of the eye
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Journal Articles

Neuroprotective effects of IL-22 during CNS inflammation (CCR4P.203)

Rachel Caspi, Mary Mattapallil, Rachael Rigden, Carlos Zarate-Blades, Phyllis Silver, Dror Luger, Chi Chao Chan
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 118.3.
https://doi.org/10.4049/jimmunol.194.Supp.118.3
Published: 01 May 2015
View article titled, Neuroprotective effects of IL-22 during CNS inflammation (CCR4P.203)
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Journal Articles

Retina-Specific T Regulatory Cells Bring About Resolution and Maintain Remission of Autoimmune Uveitis

Phyllis Silver, Reiko Horai, Jun Chen, Yingyos Jittayasothorn, Chi-Chao Chan, Rafael Villasmil, Muge R. Kesen, Rachel R. Caspi
Journal: The Journal of Immunology
J Immunol (2015) 194 (7): 3011–3019.
https://doi.org/10.4049/jimmunol.1402650
Published: 01 April 2015
View article titled, Retina-Specific T Regulatory Cells Bring About Resolution and Maintain Remission of Autoimmune Uveitis
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Includes: Supplementary data
Journal Articles

Activation of autoreactive T cells by endogenous microflora induces spontaneous autoimmunity in the immunologically privileged retina (BA8P.130)

Carlos Zarate-Blades, Reiko Horai, Jun Chen, Phyllis Silver, Patricia Dillenburg-Pilla, Hidehiro Yamane, Chi-Chao Chan, Kenya Honda, Rachel Caspi
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 113.13.
https://doi.org/10.4049/jimmunol.192.Supp.113.13
Published: 01 May 2014
View article titled, Activation of autoreactive T cells by endogenous microflora induces spontaneous autoimmunity in the immunologically privileged retina (BA8P.130)
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Journal Articles

Reciprocal interaction between NK cells and DCs regulates the Th17 response by controlling the innate IFN-γ/IL-27 axis (BA13P.124)

Wai Po Chong, Jun Chen, Phyllis Silver, Rachel Caspi
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 177.10.
https://doi.org/10.4049/jimmunol.192.Supp.177.10
Published: 01 May 2014
View article titled, Reciprocal interaction between NK cells and DCs regulates the Th17 response by controlling the innate IFN-γ/IL-27 axis (BA13P.124)
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Journal Articles

Reciprocal interaction between NK cells and DCs regulates the Th17 response by controlling the innate IFN-γ/IL-27 axis (P4067)

Rachel Caspi, Jun Chen, Phyllis Silver, R. Horai, Mary Mattapallil, Ru Zhou, WaiPo Chong
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 127.5.
https://doi.org/10.4049/jimmunol.190.Supp.127.5
Published: 01 May 2013
View article titled, Reciprocal interaction between NK cells and DCs regulates the Th17 response by controlling the innate IFN-γ/IL-27 axis (P4067)
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Journal Articles

IL27p28 inhibits induction and expression of experimental autoimmune uveitis by concurrently antagonizing autoaggressive Th1 and Th17 responses. (123.43)

Wai Po Chong, Reiko Horai, Phyllis Silver, Mary Mattapallil, Jun Chen, Rachel Caspi
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 123.43.
https://doi.org/10.4049/jimmunol.188.Supp.123.43
Published: 01 May 2012
View article titled, IL27p28 inhibits induction and expression of experimental autoimmune uveitis by concurrently antagonizing autoaggressive Th1 and Th17 responses. (123.43)
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Journal Articles

Retina-specific T regulatory cells accumulate in the eye during autoimmune uveitis and act to control inflammation (115.22)

Rachel Caspi, Reiko Horai, Jun Chen, Anna Hansen, William McManigle, Rafael Villasmil, Phyllis Silver
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 115.22.
https://doi.org/10.4049/jimmunol.186.Supp.115.22
Published: 01 April 2011
View article titled, Retina-specific T regulatory cells accumulate in the eye during autoimmune uveitis and act to control inflammation (115.22)
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Journal Articles

Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of EAU and identify autoaggressive T cells (93.1)

Mary Mattapallil, Phyllis Silver, Joseph Mattapallil, Reiko Horai, Zaruhi Karabekian, Hugh McDowell, Chi-Chao Chan, Eddie James, William Kwok, Chella David, Rachel Caspi
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 93.1.
https://doi.org/10.4049/jimmunol.184.Supp.93.1
Published: 01 April 2010
View article titled, Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of EAU and identify autoaggressive T cells (93.1)
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Journal Articles

Experimental autoimmune uveitis in mice with defective Th1 and Th17 effector responses (93.17)

Jesse Damsker, Dror Luger, Phyllis Silver, Chi-Chao Chan, Yoichiro Iwakura, Rachel Caspi
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 93.17.
https://doi.org/10.4049/jimmunol.184.Supp.93.17
Published: 01 April 2010
View article titled, Experimental autoimmune uveitis in mice with defective Th1 and Th17 effector responses (93.17)
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Journal Articles

Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune uveoretinitis (EAU) and recruitment of pathogenic ThIL17 and Th1 cells into the retina (85.29)

Xuebin Liu, Yunsang Lee, Cheng-rong Yu, Phyllis Silver, Rachel Caspi, Gery Igal, Egwuagu E Charles
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S123.
https://doi.org/10.4049/jimmunol.178.Supp.85.29
Published: 01 April 2007
View article titled, Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune uveoretinitis (EAU) and recruitment of pathogenic ThIL17 and Th1 cells into the retina (85.29)
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Journal Articles

IL-23 and IL-17 in pathogenesis of experimental ocular autoimmunity: requirement for IL–23 may extend beyond its role in sustaining the IL-17 effector response (129.26)

Rachel Caspi, Phyllis Silver, Daniel Cua, Zoe Chen, Chi-Chao Chan, Dror Luger
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): S222.
https://doi.org/10.4049/jimmunol.178.Supp.129.26
Published: 01 April 2007
View article titled, IL-23 and IL-17 in pathogenesis of experimental ocular autoimmunity: requirement for IL–23 may extend beyond its role in sustaining the IL-17 effector response (129.26)
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