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R H Schwartz
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Journal Articles

TLR ligands differentially modulate T cell responses to acute and chronic antigen presentation

N. J. Singh, M. Cox, R. H. Schwartz
Journal: The Journal of Immunology
J Immunol (2008) 180 (5): 3612.
DOI: https://doi.org/10.4049/jimmunol.180.5.3612-c
Published: 01 March 2008
View article titled, TLR ligands differentially modulate T cell responses to acute and chronic antigen presentation
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Journal Articles

Multifactor cis-dominant negative regulation of IL-2 gene expression in anergized T cells.

S Kitagawa-Sakakida, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1996) 157 (6): 2328–2339.
DOI: https://doi.org/10.4049/jimmunol.157.6.2328
Published: 15 September 1996
View article titled, Multifactor cis-dominant negative regulation of IL-2 gene expression in anergized T cells.
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Journal Articles

Subset of CD4+ T cell clones expressing IL-3 receptor alpha-chains uses IL-3 as a cofactor in autocrine growth.

D L Mueller, Z M Chen, R H Schwartz, D M Gorman, M K Kennedy
Journal: The Journal of Immunology
J Immunol (1994) 153 (7): 3014–3027.
DOI: https://doi.org/10.4049/jimmunol.153.7.3014
Published: 01 October 1994
View article titled, Subset of CD4+ T cell clones expressing IL-3 receptor alpha-chains uses IL-3 as a cofactor in autocrine growth.
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Journal Articles

Induction of competence to respond to IL-4 by CD4+ T helper type 1 cells requires costimulation.

L Chiodetti, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1992) 149 (3): 901–910.
DOI: https://doi.org/10.4049/jimmunol.149.3.901
Published: 01 August 1992
View article titled, Induction of competence to respond to IL-4 by CD4+ T helper type 1 cells requires costimulation.
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Journal Articles

Clonal anergy blocks the response to IL-4, as well as the production of IL-2, in dual-producing T helper cell clones.

D L Mueller, L Chiodetti, P A Bacon, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1991) 147 (12): 4118–4125.
DOI: https://doi.org/10.4049/jimmunol.147.12.4118
Published: 15 December 1991
View article titled, Clonal anergy blocks the response to IL-4, as well as the production of IL-2, in dual-producing T helper cell clones.
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Journal Articles

The molecular basis of class II MHC allelic control of T cell responses.

L Racioppi, F Ronchese, R H Schwartz, R N Germain
Journal: The Journal of Immunology
J Immunol (1991) 147 (11): 3718–3727.
DOI: https://doi.org/10.4049/jimmunol.147.11.3718
Published: 01 December 1991
View article titled, The molecular basis of class II MHC allelic control of T cell responses.
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Journal Articles

Transcriptional regulation of cytokine genes in nontransformed T cells. Apparent constitutive signals in run-on assays can be caused by repeat sequences.

K A Brorson, B Beverly, S M Kang, M Lenardo, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1991) 147 (10): 3601–3609.
DOI: https://doi.org/10.4049/jimmunol.147.10.3601
Published: 15 November 1991
View article titled, Transcriptional regulation of cytokine genes in nontransformed T cells. Apparent constitutive signals in run-on assays can be caused by repeat sequences.
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Journal Articles

An intracellular calcium increase and protein kinase C activation fail to initiate T cell proliferation in the absence of a costimulatory signal.

D L Mueller, M K Jenkins, L Chiodetti, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1990) 144 (10): 3701–3709.
DOI: https://doi.org/10.4049/jimmunol.144.10.3701
Published: 15 May 1990
View article titled, An intracellular calcium increase and protein kinase C activation fail to initiate T cell proliferation in the absence of a costimulatory signal.
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Journal Articles

Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody.

M K Jenkins, C A Chen, G Jung, D L Mueller, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1990) 144 (1): 16–22.
DOI: https://doi.org/10.4049/jimmunol.144.1.16
Published: 01 January 1990
View article titled, Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody.
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Journal Articles

Diminished antigen processing by endosomal acidification mutant antigen-presenting cells.

K L McCoy, J Miller, M Jenkins, F Ronchese, R N Germain, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1989) 143 (1): 29–38.
DOI: https://doi.org/10.4049/jimmunol.143.1.29
Published: 01 July 1989
View article titled, Diminished antigen processing by endosomal acidification mutant antigen-presenting cells.
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Journal Articles

An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness.

D L Mueller, M K Jenkins, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1989) 142 (8): 2617–2628.
DOI: https://doi.org/10.4049/jimmunol.142.8.2617
Published: 15 April 1989
View article titled, An accessory cell-derived costimulatory signal acts independently of protein kinase C activation to allow T cell proliferation and prevent the induction of unresponsiveness.
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Journal Articles

Functional analysis of the antigenic structure of a minor T cell determinant from pigeon cytochrome C. Evidence against an alpha-helical conformation.

K Ogasawara, W L Maloy, B Beverly, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1989) 142 (5): 1448–1456.
DOI: https://doi.org/10.4049/jimmunol.142.5.1448
Published: 01 March 1989
View article titled, Functional analysis of the antigenic structure of a minor T cell determinant from pigeon cytochrome C. Evidence against an alpha-helical conformation.
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Journal Articles

Effect of gamma radiation on resting B lymphocytes. II. Functional characterization of the antigen-presentation defect.

J D Ashwell, M K Jenkins, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1988) 141 (8): 2536–2544.
DOI: https://doi.org/10.4049/jimmunol.141.8.2536
Published: 15 October 1988
View article titled, Effect of gamma radiation on resting B lymphocytes. II. Functional characterization of the antigen-presentation defect.
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Journal Articles

Thymus-dependent and thymus-independent developmental pathways for peripheral T cell receptor-gamma delta-bearing lymphocytes.

D M Pardoll, B J Fowlkes, A M Lew, W L Maloy, M A Weston, J A Bluestone, R H Schwartz, J E Coligan, A M Kruisbeek
Journal: The Journal of Immunology
J Immunol (1988) 140 (12): 4091–4096.
DOI: https://doi.org/10.4049/jimmunol.140.12.4091
Published: 15 June 1988
View article titled, Thymus-dependent and thymus-independent developmental pathways for peripheral T cell receptor-gamma delta-bearing lymphocytes.
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Journal Articles

Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells.

M K Jenkins, J D Ashwell, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1988) 140 (10): 3324–3330.
DOI: https://doi.org/10.4049/jimmunol.140.10.3324
Published: 15 May 1988
View article titled, Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells.
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Journal Articles

Antigen-induced suppression of the proliferative response of T cell clones.

G Suzuki, Y Kawase, S Koyasu, I Yahara, Y Kobayashi, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1988) 140 (5): 1359–1365.
DOI: https://doi.org/10.4049/jimmunol.140.5.1359
Published: 01 March 1988
View article titled, Antigen-induced suppression of the proliferative response of T cell clones.
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Journal Articles

Activation properties of T cell receptor-gamma delta hybridomas expressing diversity in both gamma- and delta-chains.

S Marusić-Galesić, D M Pardoll, T Saito, O Leo, B J Fowlkes, J Coligan, R N Germain, R H Schwartz, A M Kruisbeek
Journal: The Journal of Immunology
J Immunol (1988) 140 (2): 411–418.
DOI: https://doi.org/10.4049/jimmunol.140.2.411
Published: 15 January 1988
View article titled, Activation properties of T cell receptor-gamma delta hybridomas expressing diversity in both gamma- and delta-chains.
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Journal Articles

Functionally distinct agretopic and epitopic sites. Analysis of the dominant T cell determinant of moth and pigeon cytochromes c with the use of synthetic peptide antigens.

B S Fox, C Chen, E Fraga, C A French, B Singh, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1987) 139 (5): 1578–1588.
DOI: https://doi.org/10.4049/jimmunol.139.5.1578
Published: 01 September 1987
View article titled, Functionally distinct agretopic and epitopic sites. Analysis of the dominant T cell determinant of moth and pigeon cytochromes c with the use of synthetic peptide antigens.
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Journal Articles

Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: specific induction of a long-lived state of proliferative nonresponsiveness.

H Quill, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1987) 138 (11): 3704–3712.
DOI: https://doi.org/10.4049/jimmunol.138.11.3704
Published: 01 June 1987
View article titled, Stimulation of normal inducer T cell clones with antigen presented by purified Ia molecules in planar lipid membranes: specific induction of a long-lived state of proliferative nonresponsiveness.
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Journal Articles

Quantitative analysis of the T cell response to antigen and planar membranes containing purified Ia molecules.

B S Fox, H Quill, L Carlson, R H Schwartz
Journal: The Journal of Immunology
J Immunol (1987) 138 (10): 3367–3374.
DOI: https://doi.org/10.4049/jimmunol.138.10.3367
Published: 15 May 1987
View article titled, Quantitative analysis of the T cell response to antigen and planar membranes containing purified Ia molecules.
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