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Differential effects of CTLA-4 substitutions on the binding of human CD80 (B7-1) and CD86 (B7-2).

P A Morton, X T Fu, J A Stewart, K S Giacoletto, S L White, C E Leysath, R J Evans, J J Shieh, R W Karr

J Immunol (1996) 156 (3): 1047–1054.

DOI: https://doi.org/10.4049/jimmunol.156.3.1047

Published: 01 February 1996

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Structural requirements of peptide and MHC for DR(alpha, beta 1*0401)-restricted T cell antigen recognition.

J M McNicholl, W C Whitworth, F Oftung, X Fu, T Shinnick, P E Jensen, M Simon, R M Wohlhueter, R W Karr

J Immunol (1995) 155 (4): 1951–1963.

DOI: https://doi.org/10.4049/jimmunol.155.4.1951

Published: 15 August 1995

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Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4.

E R Kearney, T L Walunas, R W Karr, P A Morton, D Y Loh, J A Bluestone, M K Jenkins

J Immunol (1995) 155 (3): 1032–1036.

DOI: https://doi.org/10.4049/jimmunol.155.3.1032

Published: 01 August 1995

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Individual effects of the DR11-variable beta-chain residues 67, 71, and 86 upon DR(alpha,beta 1*1101)-restricted, peptide-specific T cell proliferation.

J S McKinney, X T Fu, C Swearingen, E Klohe, R W Karr

J Immunol (1994) 153 (12): 5564–5571.

DOI: https://doi.org/10.4049/jimmunol.153.12.5564

Published: 15 December 1994

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Mutations in the third, but not the first or second, hypervariable regions of DR(beta 1*0101) eliminate DR1-restricted recognition of a pertussis toxin peptide.

R R Olson, M T De Magistris, A Di Tommaso, R W Karr

J Immunol (1992) 148 (9): 2703–2708.

DOI: https://doi.org/10.4049/jimmunol.148.9.2703

Published: 01 May 1992

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Antigen-specific T cells with monogamous or promiscuous restriction patterns are sensitive to different HLA-DR beta chain substitutions.

R W Karr, P Panina-Bordignon, W Y Yu, A Lanzavecchia

J Immunol (1991) 146 (12): 4242–4247.

DOI: https://doi.org/10.4049/jimmunol.146.12.4242

Published: 15 June 1991

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Polymorphic HLA-DR7 beta 1 chain residues that are involved in T cell allorecognition.

S Rosen-Bronson, W Y Yu, R W Karr

J Immunol (1991) 146 (12): 4264–4270.

DOI: https://doi.org/10.4049/jimmunol.146.12.4264

Published: 15 June 1991

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Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition.

J I Krieger, R W Karr, H M Grey, W Y Yu, D O'Sullivan, L Batovsky, Z L Zheng, S M Colón, F C Gaeta, J Sidney

J Immunol (1991) 146 (7): 2331–2340.

DOI: https://doi.org/10.4049/jimmunol.146.7.2331

Published: 01 April 1991

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Characterization of a conserved T cell epitope in HIV-1 gp41 recognized by vaccine-induced human cytolytic T cells.

S A Hammond, E Obah, P Stanhope, C R Monell, M Strand, F M Robbins, W B Bias, R W Karr, S Koenig, R F Siliciano

J Immunol (1991) 146 (5): 1470–1477.

DOI: https://doi.org/10.4049/jimmunol.146.5.1470

Published: 01 March 1991

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T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein.

M E Munk, B Schoel, S Modrow, R W Karr, R A Young, S H Kaufmann

J Immunol (1989) 143 (9): 2844–2849.

DOI: https://doi.org/10.4049/jimmunol.143.9.2844

Published: 01 November 1989

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HLA-DRB1 and -DRB4 genes are differentially regulated at the transcriptional level.

L L Stunz, R W Karr, R A Anderson

J Immunol (1989) 143 (9): 3081–3086.

DOI: https://doi.org/10.4049/jimmunol.143.9.3081

Published: 01 November 1989

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Multiple regions of HLA-DR beta 1 chains determine polymorphic epitopes recognized by monoclonal antibodies.

C A Alber, R Watts, E P Klohe, S Drover, W H Marshall, S F Radka, R W Karr

J Immunol (1989) 143 (7): 2248–2255.

DOI: https://doi.org/10.4049/jimmunol.143.7.2248

Published: 01 October 1989

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Genetic restriction and fine specificity of human T cell clones reactive with rabies virus.

E Celis, R W Karr, B Dietzschold, W H Wunner, H Koprowski

J Immunol (1988) 141 (8): 2721–2728.

DOI: https://doi.org/10.4049/jimmunol.141.8.2721

Published: 15 October 1988

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Analysis of the molecular specificities of anti-class II monoclonal antibodies by using L cell transfectants expressing HLA class II molecules.

E P Klohe, R Watts, M Bahl, C Alber, W Y Yu, R Anderson, J Silver, P K Gregersen, R W Karr

J Immunol (1988) 141 (6): 2158–2164.

DOI: https://doi.org/10.4049/jimmunol.141.6.2158

Published: 15 September 1988

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A newly characterized HLA-DP beta-chain allele. Evidence for DP beta heterogeneity within the DPw4 specificity.

B Lair, C Alber, W Y Yu, R Watts, M Bahl, R W Karr

J Immunol (1988) 141 (4): 1353–1357.

DOI: https://doi.org/10.4049/jimmunol.141.4.1353

Published: 15 August 1988

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Recombination sites in the HLA class II region are haplotype dependent.

P K Gregersen, H Kao, A Nunez-Roldan, C K Hurley, R W Karr, J Silver

J Immunol (1988) 141 (4): 1365–1368.

DOI: https://doi.org/10.4049/jimmunol.141.4.1365

Published: 15 August 1988

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Recombination between DQ alpha and DQ beta genes generates human histocompatibility leukocyte antigen class II haplotype diversity.

Q L Song, P K Gregersen, R W Karr, J Silver

J Immunol (1987) 139 (9): 2993–2995.

DOI: https://doi.org/10.4049/jimmunol.139.9.2993

Published: 01 November 1987

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Analysis of DR beta and DQ beta chain cDNA clones from a DR7 haplotype.

R W Karr, P K Gregersen, F Obata, D Goldberg, J Maccari, C Alber, J Silver

J Immunol (1986) 137 (9): 2886–2890.

DOI: https://doi.org/10.4049/jimmunol.137.9.2886

Published: 01 November 1986

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All human monocytes have the capability of expressing HLA-DQ and HLA-DP molecules upon stimulation with interferon-gamma.

T A Gonwa, J P Frost, R W Karr

J Immunol (1986) 137 (2): 519–524.

DOI: https://doi.org/10.4049/jimmunol.137.2.519

Published: 15 July 1986

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Immunochemical analysis of the Ia polymorphisms among the family of DR7-associated HLA-D specificities.

R W Karr

J Immunol (1986) 136 (3): 999–1006.

DOI: https://doi.org/10.4049/jimmunol.136.3.999

Published: 01 February 1986

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NARROW

Differential effects of CTLA-4 substitutions on the binding of human CD80 (B7-1) and CD86 (B7-2).

Structural requirements of peptide and MHC for DR(alpha, beta 1*0401)-restricted T cell antigen recognition.

Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4.

Individual effects of the DR11-variable beta-chain residues 67, 71, and 86 upon DR(alpha,beta 1*1101)-restricted, peptide-specific T cell proliferation.

Mutations in the third, but not the first or second, hypervariable regions of DR(beta 1*0101) eliminate DR1-restricted recognition of a pertussis toxin peptide.

Antigen-specific T cells with monogamous or promiscuous restriction patterns are sensitive to different HLA-DR beta chain substitutions.

Polymorphic HLA-DR7 beta 1 chain residues that are involved in T cell allorecognition.

Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition.

Characterization of a conserved T cell epitope in HIV-1 gp41 recognized by vaccine-induced human cytolytic T cells.

T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein.

HLA-DRB1 and -DRB4 genes are differentially regulated at the transcriptional level.

Multiple regions of HLA-DR beta 1 chains determine polymorphic epitopes recognized by monoclonal antibodies.

Genetic restriction and fine specificity of human T cell clones reactive with rabies virus.

Analysis of the molecular specificities of anti-class II monoclonal antibodies by using L cell transfectants expressing HLA class II molecules.

A newly characterized HLA-DP beta-chain allele. Evidence for DP beta heterogeneity within the DPw4 specificity.

Recombination sites in the HLA class II region are haplotype dependent.

Recombination between DQ alpha and DQ beta genes generates human histocompatibility leukocyte antigen class II haplotype diversity.

Analysis of DR beta and DQ beta chain cDNA clones from a DR7 haplotype.

All human monocytes have the capability of expressing HLA-DQ and HLA-DP molecules upon stimulation with interferon-gamma.

Immunochemical analysis of the Ia polymorphisms among the family of DR7-associated HLA-D specificities.

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