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R. M. Zinkernagel
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Journal Articles

Antiviral B Cell Memory in the Absence of Mature Follicular Dendritic Cell Networks and Classical Germinal Centers in TNFR1−/− Mice

U. Karrer, C. López-Macías, A. Oxenius, B. Odermatt, M. F. Bachmann, U. Kalinke, H. Bluethmann, H. Hengartner, R. M. Zinkernagel
Journal: The Journal of Immunology
J Immunol (2000) 164 (2): 768–778.
https://doi.org/10.4049/jimmunol.164.2.768
Published: 15 January 2000
View articletitled, Antiviral B Cell Memory in the Absence of Mature Follicular Dendritic Cell Networks and Classical Germinal Centers in TNFR1−/− Mice
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Journal Articles

Lactate dehydrogenase-elevating virus (LDV): lifelong coexistence of virus and LDV-specific immunity.

M F van den Broek, R Spörri, C Even, P G Plagemann, E Hänseler, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1997) 159 (4): 1585–1588.
https://doi.org/10.4049/jimmunol.159.4.1585
Published: 15 August 1997
View articletitled, Lactate dehydrogenase-elevating virus (LDV): lifelong coexistence of virus and LDV-specific immunity.
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Journal Articles

Functional in vivo MHC class II loading by endogenously synthesized glycoprotein during viral infection.

A Oxenius, M F Bachmann, D Mathis, C Benoist, R M Zinkernagel, H Hengartner
Journal: The Journal of Immunology
J Immunol (1997) 158 (12): 5717–5726.
https://doi.org/10.4049/jimmunol.158.12.5717
Published: 15 June 1997
View articletitled, Functional in vivo MHC class II loading by endogenously synthesized glycoprotein during viral infection.
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Journal Articles

Correlation of tolerogenicity of a viral antigen with its immunogenicity.

M F Bachmann, T Fehr, G Freer, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1997) 158 (11): 5106–5111.
https://doi.org/10.4049/jimmunol.158.11.5106
Published: 01 June 1997
View articletitled, Correlation of tolerogenicity of a viral antigen with its immunogenicity.
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Journal Articles

T cell development in CD8-/- mice. Thymic positive selection is biased toward the helper phenotype.

M F Bachmann, A Oxenius, T W Mak, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1995) 155 (8): 3727–3733.
https://doi.org/10.4049/jimmunol.155.8.3727
Published: 15 October 1995
View articletitled, T cell development in CD8-/- mice. Thymic positive selection is biased toward the helper phenotype.
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Journal Articles

Peptides control the gain and loss of allele specificity by mutated MHC class I molecules.

H Hengel, K Burke, D Kyburz, R M Zinkernagel, U H Koszinowski
Journal: The Journal of Immunology
J Immunol (1995) 154 (9): 4557–4564.
https://doi.org/10.4049/jimmunol.154.9.4557
Published: 01 May 1995
View articletitled, Peptides control the gain and loss of allele specificity by mutated MHC class I molecules.
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Journal Articles

Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells.

M F Bachmann, T M Kündig, B Odermatt, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1994) 153 (8): 3386–3397.
https://doi.org/10.4049/jimmunol.153.8.3386
Published: 15 October 1994
View articletitled, Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells.
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Journal Articles

MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice.

D Moskophidis, F Lechner, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1994) 152 (10): 4976–4983.
https://doi.org/10.4049/jimmunol.152.10.4976
Published: 15 May 1994
View articletitled, MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice.
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Journal Articles

How many specific B cells are needed to protect against a virus?

M F Bachmann, T M Kündig, C P Kalberer, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1994) 152 (9): 4235–4241.
https://doi.org/10.4049/jimmunol.152.9.4235
Published: 01 May 1994
View articletitled, How many specific B cells are needed to protect against a virus?
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Journal Articles

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells.

M Battegay, D Moskophidis, H Waldner, M A Bründler, W P Fung-Leung, T W Mak, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1993) 151 (10): 5408–5415.
https://doi.org/10.4049/jimmunol.151.10.5408
Published: 15 November 1993
View articletitled, Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells.
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Journal Articles

Peripheral T cells in mice lacking p56lck do not express significant antiviral effector functions.

T J Molina, M F Bachmann, T M Kündig, R M Zinkernagel, T W Mak
Journal: The Journal of Immunology
J Immunol (1993) 151 (2): 699–706.
https://doi.org/10.4049/jimmunol.151.2.699
Published: 15 July 1993
View articletitled, Peripheral T cells in mice lacking p56lck do not express significant antiviral effector functions.
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Journal Articles

Virus-specific cytotoxic T cell-mediated lysis of lymphocytes in vitro and in vivo.

D Kyburz, D E Speiser, T Aebischer, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1993) 150 (11): 5051–5058.
https://doi.org/10.4049/jimmunol.150.11.5051
Published: 01 June 1993
View articletitled, Virus-specific cytotoxic T cell-mediated lysis of lymphocytes in vitro and in vivo.
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Journal Articles

Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha.

P S Ohashi, S Oehen, P Aichele, H Pircher, B Odermatt, P Herrera, Y Higuchi, K Buerki, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1993) 150 (11): 5185–5194.
https://doi.org/10.4049/jimmunol.150.11.5185
Published: 01 June 1993
View articletitled, Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha.
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Journal Articles

Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells.

T M Kündig, M F Bachmann, L Lefrancois, L Puddington, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1993) 150 (10): 4450–4456.
https://doi.org/10.4049/jimmunol.150.10.4450
Published: 15 May 1993
View articletitled, Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells.
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Journal Articles

T cell-dependent IFN-gamma exerts an antiviral effect in the central nervous system but not in peripheral solid organs.

T M Kündig, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1993) 150 (6): 2316–2321.
https://doi.org/10.4049/jimmunol.150.6.2316
Published: 15 March 1993
View articletitled, T cell-dependent IFN-gamma exerts an antiviral effect in the central nervous system but not in peripheral solid organs.
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Journal Articles

Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic T cell reactivities. Low T cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in vivo protection.

D E Speiser, D Kyburz, U Stübi, H Hengartner, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1992) 149 (3): 972–980.
https://doi.org/10.4049/jimmunol.149.3.972
Published: 01 August 1992
View articletitled, Discrepancy between in vitro measurable and in vivo virus neutralizing cytotoxic T cell reactivities. Low T cell receptor specificity and avidity sufficient for in vitro proliferation or cytotoxicity to peptide-coated target cells but not for in vivo protection.
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Journal Articles

Effects of treatment with IL-2 receptor specific monoclonal antibody in mice.

T P Leist, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1990) 144 (7): 2847.
https://doi.org/10.4049/jimmunol.144.7.2847
Published: 01 April 1990
View articletitled, Effects of treatment with IL-2 receptor specific monoclonal antibody in mice.
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Journal Articles

Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice.

A Fontana, K Frei, S Bodmer, E Hofer, M H Schreier, M A Palladino, Jr, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1989) 143 (10): 3230–3234.
https://doi.org/10.4049/jimmunol.143.10.3230
Published: 15 November 1989
View articletitled, Transforming growth factor-beta inhibits the generation of cytotoxic T cells in virus-infected mice.
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Journal Articles

Effects of treatment with IL-2 receptor specific monoclonal antibody in mice. Inhibition of cytotoxic T cell responses but not of T help.

T P Leist, M Kohler, M Eppler, R M Zinkernagel
Journal: The Journal of Immunology
J Immunol (1989) 143 (2): 628–632.
https://doi.org/10.4049/jimmunol.143.2.628
Published: 15 July 1989
View articletitled, Effects of treatment with IL-2 receptor specific monoclonal antibody in mice. Inhibition of cytotoxic T cell responses but not of T help.
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Journal Articles

Treatment with high doses of anti-IgM prevents, but with lower doses accelerates autoimmune disease in (NZW x BXSB)F1 hybrid mice.

A Cerny, M Starobinski, A W Hügin, S Sutter, R M Zinkernagel, S Izui
Journal: The Journal of Immunology
J Immunol (1987) 138 (12): 4222–4228.
https://doi.org/10.4049/jimmunol.138.12.4222
Published: 15 June 1987
View articletitled, Treatment with high doses of anti-IgM prevents, but with lower doses accelerates autoimmune disease in (NZW x BXSB)F1 hybrid mice.
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