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Rafick-Pierre Sekaly
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Journal Articles

STINGing CD4+ T cells to induce refractoriness to HIV infection

Jeffrey Alan Tomalka, Naseem Sadek, Sarah Welbourn, David Gordon, Rafick-Pierre Sekaly
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 75.43.
https://doi.org/10.4049/jimmunol.210.Supp.75.43
Published: 01 May 2023
View article titled, STINGing CD4+ T cells to induce refractoriness to HIV infection
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LAIR-1 expression on SIV-specific CD8 T cells is associated with T cell impairment and disease progression

Sakthivel Govindaraj, Asish Arunkumar Sharma, Syed Ali, Hemalatha Babu, Katheleen Busman-Sahay, Steven Bosinger, Jacob Estes, Rafick-Pierre Sekaly, Francois Villenger, Rama Rao Amara, Vijayakumar Velu
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 226.02.
https://doi.org/10.4049/jimmunol.210.Supp.226.02
Published: 01 May 2023
View article titled, LAIR-1 expression on SIV-specific CD8 T cells is associated with T cell impairment and disease progression
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Journal Articles

Characterization of a novel dengue virus strain and its implication for vaccine development

Rita E Chen, John M Errico, David Gordon, Kimberly A. Dowd, M. Jane Cardosa, Carlos A. Sariol, Esper G. Kallas, Rafick-Pierre Sekaly, Nikos Vasilakis, Ted Pierson, Daved H. Fremont, Michael S. Diamond
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 249.16.
https://doi.org/10.4049/jimmunol.204.Supp.249.16
Published: 01 May 2020
View article titled, Characterization of a novel dengue virus strain and its implication for vaccine development
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Journal Articles

Transcriptomic meta-analysis reveals signatures of chronic inflammation in the classical monocyte population

Jackelyn Golden, Brian Richardson, Divya Seth, Michael Cartwright, Rafick-Pierre Sekaly, Thomas S. McCormick, Kevin D. Cooper, Cheryl M. Cameron, Mark J. Cameron
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 42.25.
https://doi.org/10.4049/jimmunol.200.Supp.42.25
Published: 01 May 2018
View article titled, Transcriptomic meta-analysis reveals signatures of chronic inflammation in the classical monocyte population
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Journal Articles

Effect of Anti–IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques

Maren Q. DeGottardi, Afam A. Okoye, Mukta Vaidya, Aarthi Talla, Audrie L. Konfe, Matthew D. Reyes, Joseph A. Clock, Derick M. Duell, Alfred W. Legasse, Amit Sabnis, Byung S. Park, Michael K. Axthelm, Jacob D. Estes, Keith A. Reiman, Rafick-Pierre Sekaly, Louis J. Picker
Journal: The Journal of Immunology
J Immunol (2016) 197 (4): 1183–1198.
https://doi.org/10.4049/jimmunol.1600065
Published: 15 August 2016
View article titled, Effect of Anti–IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques
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Includes: Supplementary data
Journal Articles

IL-15 drives CD8 T cell cycling and differentiation in chronic HIV-1 infection (VIR6P.1162)

souheil younes, carey shive, Arnold Reynaldi, Michael Freeman, Soumya Panigrahi, Jacob Estes, Jodi Anderson, Timothy Schacker, Miles Davenport, Joseph McCune, Peter Hunt, Sulggi Lee, Sergio Serrano-Villar, David Canaday, Cheryl Cameron, Rafick-Pierre Sekaly, Benigno Rodriguez, Scott Sieg, Michael Lederman
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 149.2.
https://doi.org/10.4049/jimmunol.194.Supp.149.2
Published: 01 May 2015
View article titled, IL-15 drives CD8 T cell cycling and differentiation in chronic HIV-1 infection (VIR6P.1162)
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Journal Articles

Microarray analysis reveals novel insights into immunity to H1N1/09 influenza vaccine in aviremic HIV infected children and adolescents in IMPAACT P1088 (VIR2P.1024)

Lesley de Armas, Varghese George, Courtney Steel, Ali Filali, Peter Wilkinson, Anita Parmigiani, Samita Andreansky, Ivan Gonzalez, Adriana Weinberg, Coleen Cunningham, Lydie Trautmann, Rafick-Pierre Sekaly, Mark Cameron, Savita Pahwa
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 75.13.
https://doi.org/10.4049/jimmunol.192.Supp.75.13
Published: 01 May 2014
View article titled, Microarray analysis reveals novel insights into immunity to H1N1/09 influenza vaccine in aviremic HIV infected children and adolescents in IMPAACT P1088 (VIR2P.1024)
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Journal Articles

MMTV Superantigens Coerce an Unconventional Topology between the TCR and MHC Class II

Jean-Simon Fortin, Laetitia Genève, Catherine Gauthier, Naglaa H. Shoukry, Georges A. Azar, Souheil Younes, Bader Yassine-Diab, Rafick-Pierre Sékaly, Daved H. Fremont, Jacques Thibodeau
Journal: The Journal of Immunology
J Immunol (2014) 192 (4): 1896–1906.
https://doi.org/10.4049/jimmunol.1203130
Published: 15 February 2014
View article titled, MMTV Superantigens Coerce an Unconventional Topology between the TCR and MHC Class II
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Includes: Supplementary data
Journal Articles

Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection

Gaëlle Breton, Nicolas Chomont, Hiroshi Takata, Rémi Fromentin, Jeffrey Ahlers, Abdelali Filali-Mouhim, Catherine Riou, Mohamed-Rachid Boulassel, Jean-Pierre Routy, Bader Yassine-Diab, Rafick-Pierre Sékaly
Journal: The Journal of Immunology
J Immunol (2013) 191 (5): 2194–2204.
https://doi.org/10.4049/jimmunol.1200646
Published: 01 September 2013
View article titled, Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection
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Includes: Supplementary data
Journal Articles

Cutting Edge: Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells

Ben Youngblood, Alessandra Noto, Filippos Porichis, Rama S. Akondy, Zaza M. Ndhlovu, James W. Austin, Rebeka Bordi, Francesco A. Procopio, Toshiyuki Miura, Todd M. Allen, John Sidney, Alessandro Sette, Bruce D. Walker, Rafi Ahmed, Jeremy M. Boss, Rafick-Pierre Sékaly, Daniel E. Kaufmann
Journal: The Journal of Immunology
J Immunol (2013) 191 (2): 540–544.
https://doi.org/10.4049/jimmunol.1203161
Published: 15 July 2013
View article titled, Cutting Edge: Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells
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Includes: Supplementary data
Journal Articles

Intrinsic Role of FoxO3a in the Development of CD8+ T Cell Memory

Fanny Tzelepis, Julie Joseph, Elias K. Haddad, Susanne MacLean, Renu Dudani, Fabien Agenes, Stanford L. Peng, Rafick-Pierre Sekaly, Subash Sad
Journal: The Journal of Immunology
J Immunol (2013) 190 (3): 1066–1075.
https://doi.org/10.4049/jimmunol.1200639
Published: 01 February 2013
View article titled, Intrinsic Role of FoxO3a in the Development of CD8<sup>+</sup> T Cell Memory
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Includes: Supplementary data
Journal Articles

Type I IFN Induced by Adenovirus Serotypes 28 and 35 Has Multiple Effects on T Cell Immunogenicity

Matthew J. Johnson, Constantinos Petrovas, Takuya Yamamoto, Ross W. B. Lindsay, Karin Loré, Jason G. D. Gall, Emma Gostick, François Lefebvre, Mark J. Cameron, David A. Price, Elias Haddad, Rafick-Pierre Sekaly, Robert A. Seder, Richard A. Koup
Journal: The Journal of Immunology
J Immunol (2012) 188 (12): 6109–6118.
https://doi.org/10.4049/jimmunol.1103717
Published: 15 June 2012
View article titled, Type I IFN Induced by Adenovirus Serotypes 28 and 35 Has Multiple Effects on T Cell Immunogenicity
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Includes: Supplementary data
Journal Articles

Clonotype and Repertoire Changes Drive the Functional Improvement of HIV-Specific CD8 T Cell Populations under Conditions of Limited Antigenic Stimulation

Loury Janbazian, David A. Price, Glenda Canderan, Abdelali Filali-Mouhim, Tedi E. Asher, David R. Ambrozak, Phillip Scheinberg, Mohamad Rachid Boulassel, Jean-Pierre Routy, Richard A. Koup, Daniel C. Douek, Rafick-Pierre Sekaly, Lydie Trautmann
Journal: The Journal of Immunology
J Immunol (2012) 188 (3): 1156–1167.
https://doi.org/10.4049/jimmunol.1102610
Published: 01 February 2012
View article titled, Clonotype and Repertoire Changes Drive the Functional Improvement of HIV-Specific CD8 T Cell Populations under Conditions of Limited Antigenic Stimulation
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Includes: Supplementary data
Journal Articles

Dendritic Cell Inhibition Is Connected to Exhaustion of CD8+ T Cell Polyfunctionality during Chronic Hepatitis C Virus Infection

Ian Gaël Rodrigue-Gervais, Hawley Rigsby, Loubna Jouan, Dominike Sauvé, Rafick-Pierre Sékaly, Bernard Willems, Daniel Lamarre
Journal: The Journal of Immunology
J Immunol (2010) 184 (6): 3134–3144.
https://doi.org/10.4049/jimmunol.0902522
Published: 15 March 2010
View article titled, Dendritic Cell Inhibition Is Connected to Exhaustion of CD8<sup>+</sup> T Cell Polyfunctionality during Chronic Hepatitis C Virus Infection
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Includes: Supplementary data
Journal Articles

Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

Annie Gosselin, Patricia Monteiro, Nicolas Chomont, Felipe Diaz-Griffero, Elias A. Said, Simone Fonseca, Vanessa Wacleche, Mohamed El-Far, Mohamed-Rachid Boulassel, Jean-Pierre Routy, Rafick-Pierre Sekaly, Petronela Ancuta
Journal: The Journal of Immunology
J Immunol (2010) 184 (3): 1604–1616.
https://doi.org/10.4049/jimmunol.0903058
Published: 30 December 2009
View article titled, Peripheral Blood CCR4<sup>+</sup>CCR6<sup>+</sup> and CXCR3<sup>+</sup>CCR6<sup>+</sup> CD4<sup>+</sup> T Cells Are Highly Permissive to HIV-1 Infection
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Includes: Supplementary data
Journal Articles

Therapeutic Vaccination with Simian Immunodeficiency Virus (SIV)-DNA+IL-12 or IL-15 Induces Distinct CD8 Memory Subsets in SIV-Infected Macaques

Rabih Halwani, Jean D. Boyer, Bader Yassine-Diab, Elias K. Haddad, Tara M. Robinson, Sanjeev Kumar, Rose Parkinson, Ling Wu, Maninder K. Sidhu, Rebecca Phillipson-Weiner, George N. Pavlakis, Barbara K. Felber, Mark G. Lewis, Anding Shen, Robert F. Siliciano, David B. Weiner, Rafick-Pierre Sekaly
Journal: The Journal of Immunology
J Immunol (2008) 180 (12): 7969–7979.
https://doi.org/10.4049/jimmunol.180.12.7969
Published: 15 June 2008
View article titled, Therapeutic Vaccination with Simian Immunodeficiency Virus (SIV)-DNA+IL-12 or IL-15 Induces Distinct CD8 Memory Subsets in SIV-Infected Macaques
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Journal Articles

The Duration of Exposure to HIV Modulates the Breadth and the Magnitude of HIV-Specific Memory CD4+ T Cells

Souheil-Antoine Younes, Lydie Trautmann, Bader Yassine-Diab, Lena H. Kalfayan, Anne-Elen Kernaleguen, Thomas O. Cameron, Rachid Boulassel, Lawrence J. Stern, Jean-Pierre Routy, Zvi Grossman, Alain R. Dumont, Rafick-Pierre Sekaly
Journal: The Journal of Immunology
J Immunol (2007) 178 (2): 788–797.
https://doi.org/10.4049/jimmunol.178.2.788
Published: 15 January 2007
View article titled, The Duration of Exposure to HIV Modulates the Breadth and the Magnitude of HIV-Specific Memory CD4<sup>+</sup> T Cells
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Journal Articles

Evaluation of OX40 Ligand as a Costimulator of Human Antiviral Memory CD8 T Cell Responses: Comparison with B7.1 and 4-1BBL

Lena Serghides, Jacob Bukczynski, Tao Wen, Chao Wang, Jean-Pierre Routy, Mohamed-Rachid Boulassel, Rafick-Pierre Sekaly, Mario Ostrowski, Nicole F. Bernard, Tania H. Watts
Journal: The Journal of Immunology
J Immunol (2005) 175 (10): 6368–6377.
https://doi.org/10.4049/jimmunol.175.10.6368
Published: 15 November 2005
View article titled, Evaluation of OX40 Ligand as a Costimulator of Human Antiviral Memory CD8 T Cell Responses: Comparison with B7.1 and 4-1BBL
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Enhancement of HIV-Specific CD8 T Cell Responses by Dual Costimulation with CD80 and CD137L

Jacob Bukczynski, Tao Wen, Chao Wang, Natasha Christie, Jean-Pierre Routy, Mohamed-Rachid Boulassel, Colin M. Kovacs, Kelly S. MacDonald, Mario Ostrowski, Rafick-Pierre Sekaly, Nicole F. Bernard, Tania H. Watts
Journal: The Journal of Immunology
J Immunol (2005) 175 (10): 6378–6389.
https://doi.org/10.4049/jimmunol.175.10.6378
Published: 15 November 2005
View article titled, Enhancement of HIV-Specific CD8 T Cell Responses by Dual Costimulation with CD80 and CD137L
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Caspase-3 Is a Component of Fas Death-Inducing Signaling Complex in Lipid Rafts and Its Activity Is Required for Complete Caspase-8 Activation during Fas-Mediated Cell Death

Salah M. Aouad, Luchino Y. Cohen, Ehsan Sharif-Askari, Elias K. Haddad, Antoine Alam, Rafick-Pierre Sekaly
Journal: The Journal of Immunology
J Immunol (2004) 172 (4): 2316–2323.
https://doi.org/10.4049/jimmunol.172.4.2316
Published: 15 February 2004
View article titled, Caspase-3 Is a Component of Fas Death-Inducing Signaling Complex in Lipid Rafts and Its Activity Is Required for Complete Caspase-8 Activation during Fas-Mediated Cell Death
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