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Richard G. Vile
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Journal Articles

A generalized pathway of immunocompromise following central nervous system insult: the release of large immunosuppressive molecules and thymic involution

Katayoun Ayasoufi, Christian K Pfaller, Roman Khadka, Fang Jin, Jiaying Zheng, Matthew R Schuelke, Laura Evgin, Michael Hansen, Benjamin Himes, Cori Fain, Zachariah Peter Tritz, Emma Goddery, Lila T Yokanovich, Larry R Pease, Richard G. Vile, Aaron J Johnson
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 72.12.
https://doi.org/10.4049/jimmunol.204.Supp.72.12
Published: 01 May 2020
View article titled, A generalized pathway of immunocompromise following central nervous system insult: the release of large immunosuppressive molecules and thymic involution
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CAR T cells generated in situ using gene therapy in naturally activated lymph node T cells

Larry R Pease, Matthew C Guttormson, Christopher A Parks, Sara J Felts, Virginia P Van Keulen, Sarah A Castro, Laura Evgin, Richard G Vile, Michael A Barry
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 246.21.
https://doi.org/10.4049/jimmunol.204.Supp.246.21
Published: 01 May 2020
View article titled, CAR T cells generated in situ using gene therapy in naturally activated lymph node T cells
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Vesicular stomatitis virus expressing destabilized tumor associated antigens with enhanced MHC class I presentation to improve anti-tumor T cell responses

Amanda Huff, Laura Evgin, Jill Thompson, Tim Kottke, Phonphimon Wongthida, Christopher Driscoll, Kevin G. Shim, Matthew Scheulke, Richard G. Vile
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 91.16.
https://doi.org/10.4049/jimmunol.204.Supp.91.16
Published: 01 May 2020
View article titled, Vesicular stomatitis virus expressing destabilized tumor associated antigens with enhanced MHC class I presentation to improve anti-tumor T cell responses
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Network-guided bioengineering of oncolytic immunovirotherapies for glioblastoma

Dileep D. Monie, Cheng Zhang, Cristina Correia, Choong Ung, Richard G. Vile, Hu Li
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 169.17.
https://doi.org/10.4049/jimmunol.204.Supp.169.17
Published: 01 May 2020
View article titled, Network-guided bioengineering of oncolytic immunovirotherapies for glioblastoma
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Reciprocal Human Dendritic Cell–Natural Killer Cell Interactions Induce Antitumor Activity Following Tumor Cell Infection by Oncolytic Reovirus

Robin J. Prestwich, Fiona Errington, Lynette P. Steele, Elizabeth J. Ilett, Ruth S. M. Morgan, Kevin J. Harrington, Hardev S. Pandha, Peter J. Selby, Richard G. Vile, Alan A. Melcher
Journal: The Journal of Immunology
J Immunol (2009) 183 (7): 4312–4321.
https://doi.org/10.4049/jimmunol.0901074
Published: 01 October 2009
View article titled, Reciprocal Human Dendritic Cell–Natural Killer Cell Interactions Induce Antitumor Activity Following Tumor Cell Infection by Oncolytic Reovirus
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Human Bone Marrow: A Reservoir for “Enhanced Effector Memory” CD8+ T Cells with Potent Recall Function

Xiaoyu Zhang, Haidong Dong, Wei Lin, Stephen Voss, Lucinda Hinkley, Melissa Westergren, Guoliang Tian, Daniel Berry, David Lewellen, Richard G. Vile, Lieping Chen, Donna L. Farber, Scott E. Strome
Journal: The Journal of Immunology
J Immunol (2006) 177 (10): 6730–6737.
https://doi.org/10.4049/jimmunol.177.10.6730
Published: 15 November 2006
View article titled, Human Bone Marrow: A Reservoir for “Enhanced Effector Memory” CD8<sup>+</sup> T Cells with Potent Recall Function
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Killing of Normal Melanocytes, Combined with Heat Shock Protein 70 and CD40L Expression, Cures Large Established Melanomas

Luis Sanchez-Perez, Timothy Kottke, Gregory A. Daniels, Rosa Maria Diaz, Jill Thompson, Jose Pulido, Alan Melcher, Richard G. Vile
Journal: The Journal of Immunology
J Immunol (2006) 177 (6): 4168–4177.
https://doi.org/10.4049/jimmunol.177.6.4168
Published: 15 September 2006
View article titled, Killing of Normal Melanocytes, Combined with Heat Shock Protein 70 and CD40L Expression, Cures Large Established Melanomas
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MIP-3α Transfection into a Rodent Tumor Cell Line Increases Intratumoral Dendritic Cell Infiltration but Enhances (Facilitates) Tumor Growth and Decreases Immunogenicity

Bernard Bonnotte, Marka Crittenden, Nicolas Larmonier, Michael Gough, Richard G. Vile
Journal: The Journal of Immunology
J Immunol (2004) 173 (8): 4929–4935.
https://doi.org/10.4049/jimmunol.173.8.4929
Published: 15 October 2004
View article titled, MIP-3α Transfection into a Rodent Tumor Cell Line Increases Intratumoral Dendritic Cell Infiltration but Enhances (Facilitates) Tumor Growth and Decreases Immunogenicity
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Journal Articles

Induction of Human T Lymphocyte Cytotoxicity and Inhibition of Tumor Growth by Tumor-Specific Diabody-Based Molecules Secreted from Gene-Modified Bystander Cells

Belén Blanco, Phillip Holliger, Richard G. Vile, Luis Álvarez-Vallina
Journal: The Journal of Immunology
J Immunol (2003) 171 (2): 1070–1077.
https://doi.org/10.4049/jimmunol.171.2.1070
Published: 15 July 2003
View article titled, Induction of Human T Lymphocyte Cytotoxicity and Inhibition of Tumor Growth by Tumor-Specific Diabody-Based Molecules Secreted from Gene-Modified Bystander Cells
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Heat Shock Protein 70 Induced During Tumor Cell Killing Induces Th1 Cytokines and Targets Immature Dendritic Cell Precursors to Enhance Antigen Uptake

Stephen Todryk, Alan A. Melcher, Nicola Hardwick, Emmanouela Linardakis, Andrew Bateman, Mario P. Colombo, Antonella Stoppacciaro, Richard G. Vile
Journal: The Journal of Immunology
J Immunol (1999) 163 (3): 1398–1408.
https://doi.org/10.4049/jimmunol.163.3.1398
Published: 01 August 1999
View article titled, Heat Shock Protein 70 Induced During Tumor Cell Killing Induces Th1 Cytokines and Targets Immature Dendritic Cell Precursors to Enhance Antigen Uptake
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