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Robert Lechler
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Journal Articles

Tolerogenic Donor-Derived Dendritic Cells Risk Sensitization In Vivo owing to Processing and Presentation by Recipient APCs

Lesley A. Smyth, Kulachelvy Ratnasothy, Aurelie Moreau, Sally Alcock, Pervinder Sagoo, Lucy Meader, Yakup Tanriver, Matthew Buckland, Robert Lechler, Giovanna Lombardi
Journal: The Journal of Immunology
J Immunol (2013) 190 (9): 4848–4860.
https://doi.org/10.4049/jimmunol.1200870
Published: 01 May 2013
View article titled, Tolerogenic Donor-Derived Dendritic Cells Risk Sensitization In Vivo owing to Processing and Presentation by Recipient APCs
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Includes: Supplementary data
Journal Articles

Targeting MHC Class I Monomers to Dendritic Cells Inhibits the Indirect Pathway of Allorecognition and the Production of IgG Alloantibodies Leading to Long-Term Allograft Survival

Yakup Tanriver, Kulachelvy Ratnasothy, R. Pat Bucy, Giovanna Lombardi, Robert Lechler
Journal: The Journal of Immunology
J Immunol (2010) 184 (4): 1757–1764.
https://doi.org/10.4049/jimmunol.0902987
Published: 18 January 2010
View article titled, Targeting MHC Class I Monomers to Dendritic Cells Inhibits the Indirect Pathway of Allorecognition and the Production of IgG Alloantibodies Leading to Long-Term Allograft Survival
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Journal Articles

Superantigen-Activated Regulatory T Cells Inhibit the Migration of Innate Immune Cells and the Differentiation of Naive T Cells

Yakup Tanriver, Alfonso Martín-Fontecha, Kulachelvy Ratnasothy, Giovanna Lombardi, Robert Lechler
Journal: The Journal of Immunology
J Immunol (2009) 183 (5): 2946–2956.
https://doi.org/10.4049/jimmunol.0803953
Published: 01 September 2009
View article titled, Superantigen-Activated Regulatory T Cells Inhibit the Migration of Innate Immune Cells and the Differentiation of Naive T Cells
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Journal Articles

The Relative Efficiency of Acquisition of MHC:Peptide Complexes and Cross-Presentation Depends on Dendritic Cell Type

Lesley Ann Smyth, Nicola Harker, Wayne Turnbull, Haytham El-Doueik, Linda Klavinskis, Dimitris Kioussis, Giovanna Lombardi, Robert Lechler
Journal: The Journal of Immunology
J Immunol (2008) 181 (5): 3212–3220.
https://doi.org/10.4049/jimmunol.181.5.3212
Published: 01 September 2008
View article titled, The Relative Efficiency of Acquisition of MHC:Peptide Complexes and Cross-Presentation Depends on Dendritic Cell Type
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Journal Articles

Quantitating Effector and Regulatory T Lymphocytes in Immune Responses by Limiting Dilution Analysis Modeling

Thierry Bonnefoix, Philippe Bonnefoix, Pascal Perron, Jian-Qing Mi, Wan Fai Ng, Robert Lechler, Jean-Claude Bensa, Jean-Yves Cahn, Dominique Leroux
Journal: The Journal of Immunology
J Immunol (2005) 174 (6): 3421–3431.
https://doi.org/10.4049/jimmunol.174.6.3421
Published: 15 March 2005
View article titled, Quantitating Effector and Regulatory T Lymphocytes in Immune Responses by Limiting Dilution Analysis Modeling
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Journal Articles

Cutting Edge: CTLA-4 (CD152) Differentially Regulates Mitogen-Activated Protein Kinases (Extracellular Signal-Regulated Kinase and c-Jun N-Terminal Kinase) in CD4+ T Cells from Receptor/Ligand-Deficient Mice

Helga Schneider, Didier A. Mandelbrot, Rebecca J. Greenwald, Fai Ng, Robert Lechler, Arlene H. Sharpe, Christopher E. Rudd
Journal: The Journal of Immunology
J Immunol (2002) 169 (7): 3475–3479.
https://doi.org/10.4049/jimmunol.169.7.3475
Published: 01 October 2002
View article titled, Cutting Edge: CTLA-4 (CD152) Differentially Regulates Mitogen-Activated Protein Kinases (Extracellular Signal-Regulated Kinase and c-Jun N-Terminal Kinase) in CD4<sup>+</sup> T Cells from Receptor/Ligand-Deficient Mice
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Journal Articles

HLA-DP Allele-Specific T Cell Responses to Beryllium Account for DP-Associated Susceptibility to Chronic Beryllium Disease

Giovanna Lombardi, Conrad Germain, Julia Uren, Maria Teresa Fiorillo, Ronald M. du Bois, William Jones-Williams, Cesare Saltini, Rosa Sorrentino, Robert Lechler
Journal: The Journal of Immunology
J Immunol (2001) 166 (5): 3549–3555.
https://doi.org/10.4049/jimmunol.166.5.3549
Published: 01 March 2001
View article titled, HLA-DP Allele-Specific T Cell Responses to Beryllium Account for DP-Associated Susceptibility to Chronic Beryllium Disease
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Journal Articles

Amino Acid Substitutions in the Putative MHC Class II “Dimer of Dimers” Interface Inhibit CD4+ T Cell Activation

Ragnar Lindstedt, Nicola Monk, Giovanna Lombardi, Robert Lechler
Journal: The Journal of Immunology
J Immunol (2001) 166 (2): 800–808.
https://doi.org/10.4049/jimmunol.166.2.800
Published: 15 January 2001
View article titled, Amino Acid Substitutions in the Putative MHC Class II “Dimer of Dimers” Interface Inhibit CD4<sup>+</sup> T Cell Activation
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Journal Articles

CD152 Ligation by CD80 on T Cells Is Required for the Induction of Unresponsiveness by Costimulation-Deficient Antigen Presentation

Jian-Guo Chai, Silvia Vendetti, Eunice Amofah, Julian Dyson, Robert Lechler
Journal: The Journal of Immunology
J Immunol (2000) 165 (6): 3037–3042.
https://doi.org/10.4049/jimmunol.165.6.3037
Published: 15 September 2000
View article titled, CD152 Ligation by CD80 on T Cells Is Required for the Induction of Unresponsiveness by Costimulation-Deficient Antigen Presentation
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Journal Articles

Anergic T Cells Inhibit the Antigen-Presenting Function of Dendritic Cells

Silvia Vendetti, Jian-Guo Chai, Julian Dyson, Elizabeth Simpson, Giovanna Lombardi, Robert Lechler
Journal: The Journal of Immunology
J Immunol (2000) 165 (3): 1175–1181.
https://doi.org/10.4049/jimmunol.165.3.1175
Published: 01 August 2000
View article titled, Anergic T Cells Inhibit the Antigen-Presenting Function of Dendritic Cells
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Journal Articles

Critical Role of Costimulation in the Activation of Naive Antigen-Specific TCR Transgenic CD8+ T Cells In Vitro

Jian-Guo Chai, Silvia Vendetti, Istvan Bartok, Diana Schoendorf, Katalin Takacs, James Elliott, Robert Lechler, Julian Dyson
Journal: The Journal of Immunology
J Immunol (1999) 163 (3): 1298–1305.
https://doi.org/10.4049/jimmunol.163.3.1298
Published: 01 August 1999
View article titled, Critical Role of Costimulation in the Activation of Naive Antigen-Specific TCR Transgenic CD8<sup>+</sup> T Cells In Vitro
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Journal Articles

T:T Antigen Presentation by Activated Murine CD8+ T Cells Induces Anergy and Apoptosis

Jian-Guo Chai, Istvan Bartok, Diane Scott, Julian Dyson, Robert Lechler
Journal: The Journal of Immunology
J Immunol (1998) 160 (8): 3655–3665.
https://doi.org/10.4049/jimmunol.160.8.3655
Published: 15 April 1998
View article titled, T:T Antigen Presentation by Activated Murine CD8<sup>+</sup> T Cells Induces Anergy and Apoptosis
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