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Roberto Spreafico
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Journal Articles

An adjuvant strategy enabled by modulation of the physical properties of fungal mannans elicits pan-coronavirus reactive anti-SARS-CoV-2 Spike antibodies

In Special Collection:
COVID-19, SARS, and MERS Articles
Francesco Borriello, Roberto Spreafico, Valentina Poli, Ellen Shrock, Janet Chou, Nora A. Barrett, Lucrezia Lacanfora, Marcella E. Franco, Laura Marongiu, Yoichiro Iwakura, Ferdinando Pucci, Michael D. Kruppa, Zuchao Ma, Douglas W. Lowman, Harry E. Ensley, Etsuro Nanishi, Yoshine Saito, Timothy R. O’Meara, Hyuk-Soo Seo, Marisa E. McGrath, James Logue, Robert E. Haupt, Sirano Dhe-Paganon, David J. Dowling, Matthew Frieman, Stephen J. Elledge, Ofer Levy, Darrell J. Irvine, David L. Williams, Ivan Zanoni
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 30.08.
https://doi.org/10.4049/jimmunol.206.Supp.30.08
Published: 01 May 2021
View article titled, An adjuvant strategy enabled by modulation of the physical properties of fungal mannans elicits pan-coronavirus reactive anti-SARS-CoV-2 Spike antibodies
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Journal Articles

The Syk–NFAT–IL-2 Pathway in Dendritic Cells Is Required for Optimal Sterile Immunity Elicited by Alum Adjuvants

Hanif Javanmard Khameneh, Adrian W. S. Ho, Roberto Spreafico, Heidi Derks, Hazel Q. Y. Quek, Alessandra Mortellaro
Journal: The Journal of Immunology
J Immunol (2017) 198 (1): 196–204.
https://doi.org/10.4049/jimmunol.1600420
Published: 01 January 2017
View article titled, The Syk–NFAT–IL-2 Pathway in Dendritic Cells Is Required for Optimal Sterile Immunity Elicited by Alum Adjuvants
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Includes: Supplementary data
Journal Articles

Ex Vivo–Expanded but Not In Vitro–Induced Human Regulatory T Cells Are Candidates for Cell Therapy in Autoimmune Diseases Thanks to Stable Demethylation of the FOXP3 Regulatory T Cell–Specific Demethylated Region

Maura Rossetti, Roberto Spreafico, Suzan Saidin, Camillus Chua, Maryam Moshref, Jing Yao Leong, York Kiat Tan, Julian Thumboo, Jorg van Loosdregt, Salvatore Albani
Journal: The Journal of Immunology
J Immunol (2015) 194 (1): 113–124.
https://doi.org/10.4049/jimmunol.1401145
Published: 01 January 2015
View article titled, Ex Vivo–Expanded but Not In Vitro–Induced Human Regulatory T Cells Are Candidates for Cell Therapy in Autoimmune Diseases Thanks to Stable Demethylation of the FOXP3 Regulatory T Cell–Specific Demethylated Region
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Journal Articles

Human CD4+CD3− Innate-Like T Cells Provide a Source of TNF and Lymphotoxin-αβ and Are Elevated in Rheumatoid Arthritis

Vasileios Bekiaris, John R. Šedý, Maura Rossetti, Roberto Spreafico, Shilpi Sharma, Antje Rhode-Kurnow, Brian C. Ware, Nini Huang, Matthew G. Macauley, Paula S. Norris, Salvatore Albani, Carl F. Ware
Journal: The Journal of Immunology
J Immunol (2013) 191 (9): 4611–4618.
https://doi.org/10.4049/jimmunol.1301672
Published: 01 November 2013
View article titled, Human CD4<sup>+</sup>CD3<sup>−</sup> Innate-Like T Cells Provide a Source of TNF and Lymphotoxin-αβ and Are Elevated in Rheumatoid Arthritis
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Includes: Supplementary data
Journal Articles

Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release

Federica Laudisi, Roberto Spreafico, Maximilien Evrard, Timothy R. Hughes, Barbara Mandriani, Matheswaran Kandasamy, B. Paul Morgan, Baalasubramanian Sivasankar, Alessandra Mortellaro
Journal: The Journal of Immunology
J Immunol (2013) 191 (3): 1006–1010.
https://doi.org/10.4049/jimmunol.1300489
Published: 01 August 2013
View article titled, Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release
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Includes: Supplementary data
Journal Articles

Uric acid acts as a natural adjuvant by promoting Th17 cell differentiation via an inflammasome-dependent mechanism (176.28)

Alessandra Mortellaro, Cristina Conforti-Andreoni, Roberto Spreafico, Paola Ricciardi-Castagnoli
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 176.28.
https://doi.org/10.4049/jimmunol.188.Supp.176.28
Published: 01 May 2012
View article titled, Uric acid acts as a natural adjuvant by promoting Th17 cell differentiation via an inflammasome-dependent mechanism (176.28)
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Journal Articles

Uric Acid-Driven Th17 Differentiation Requires Inflammasome-Derived IL-1 and IL-18

Cristina Conforti-Andreoni, Roberto Spreafico, Hong Liang Qian, Nicolas Riteau, Bernhard Ryffel, Paola Ricciardi-Castagnoli, Alessandra Mortellaro
Journal: The Journal of Immunology
J Immunol (2011) 187 (11): 5842–5850.
https://doi.org/10.4049/jimmunol.1101408
Published: 01 December 2011
View article titled, Uric Acid-Driven Th17 Differentiation Requires Inflammasome-Derived IL-1 and IL-18
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Includes: Supplementary data