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Two-Step Binding of Transcription Factors Causes Sequential Chromatin Structural Changes at the Activated IL-2 Promoter

Satoru Ishihara, Ronald H. Schwartz

J Immunol (2011) 187 (6): 3292–3299.

https://doi.org/10.4049/jimmunol.1003173

Published: 15 September 2011

View article titled, Two-Step Binding of Transcription Factors Causes Sequential Chromatin Structural Changes at the Activated IL-2 Promoter

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Includes: Supplementary data

Journal Articles

Impairment of Immunological Synapse Formation in Adaptively Tolerant T Cells

Seeyoung Choi, Ronald H. Schwartz

J Immunol (2011) 187 (2): 805–816.

https://doi.org/10.4049/jimmunol.1003314

Published: 15 July 2011

View article titled, Impairment of Immunological Synapse Formation in Adaptively Tolerant T Cells

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Includes: Supplementary data

Journal Articles

Pillars Article: Antigen Presentation by Chemically Modified Splenocytes Induces Antigen-Specific T Cell Unresponsiveness In Vitro and In Vivo. J. Exp. Med. 1987. 165: 302–319

Marc K. Jenkins, Ronald H. Schwartz

J Immunol (2009) 183 (7): 4150–4167.

Published: 01 October 2009

View article titled, Pillars Article: Antigen Presentation by Chemically Modified Splenocytes Induces Antigen-Specific T Cell Unresponsiveness In Vitro and In Vivo. J. Exp. Med. 1987. 165: 302–319

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Biphasic Regulation of Il2 Transcription in CD4⁺ T Cells: Roles for TNF-α Receptor Signaling and Chromatin Structure

Susan C. McKarns, Ronald H. Schwartz

J Immunol (2008) 181 (2): 1272–1281.

https://doi.org/10.4049/jimmunol.181.2.1272

Published: 15 July 2008

View article titled, Biphasic Regulation of Il2 Transcription in CD4+ T Cells: Roles for TNF-α Receptor Signaling and Chromatin Structure

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Journal Articles

TLR Ligands Differentially Modulate T Cell Responses to Acute and Chronic Antigen Presentation

Nevil J. Singh, Maureen Cox, Ronald H. Schwartz

J Immunol (2007) 179 (12): 7999–8008.

https://doi.org/10.4049/jimmunol.179.12.7999

Published: 15 December 2007

View article titled, TLR Ligands Differentially Modulate T Cell Responses to Acute and Chronic Antigen Presentation

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Journal Articles

Dual Effects of Sprouty1 on TCR Signaling Depending on the Differentiation State of the T Cell

Heonsik Choi, Sung-Yup Cho, Ronald H. Schwartz, Kyungho Choi

J Immunol (2006) 176 (10): 6034–6045.

https://doi.org/10.4049/jimmunol.176.10.6034

Published: 15 May 2006

View article titled, Dual Effects of Sprouty1 on TCR Signaling Depending on the Differentiation State of the T Cell

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Journal Articles

Adaptive Tolerance and Clonal Anergy Are Distinct Biochemical States

Lynda Chiodetti, Seeyoung Choi, Daniel L. Barber, Ronald H. Schwartz

J Immunol (2006) 176 (4): 2279–2291.

https://doi.org/10.4049/jimmunol.176.4.2279

Published: 15 February 2006

View article titled, Adaptive Tolerance and Clonal Anergy Are Distinct Biochemical States

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Journal Articles

Distinct Effects of TGF-β1 on CD4⁺ and CD8⁺ T Cell Survival, Division, and IL-2 Production: A Role for T Cell Intrinsic Smad3

Susan C. McKarns, Ronald H. Schwartz

J Immunol (2005) 174 (4): 2071–2083.

https://doi.org/10.4049/jimmunol.174.4.2071

Published: 15 February 2005

View article titled, Distinct Effects of TGF-β1 on CD4+ and CD8+ T Cell Survival, Division, and IL-2 Production: A Role for T Cell Intrinsic Smad3

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Journal Articles

A Distinct Region of the Murine IFN-γ Promoter Is Hypomethylated from Early T Cell Development through Mature Naive and Th1 Cell Differentiation, but Is Hypermethylated in Th2 Cells

Benjamin R. Winders, Ronald H. Schwartz, Denis Bruniquel

J Immunol (2004) 173 (12): 7377–7384.

https://doi.org/10.4049/jimmunol.173.12.7377

Published: 15 December 2004

View article titled, A Distinct Region of the Murine IFN-γ Promoter Is Hypomethylated from Early T Cell Development through Mature Naive and Th1 Cell Differentiation, but Is Hypermethylated in Th2 Cells

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Journal Articles

CTLA-4 Engagement Acts as a Brake on CD4⁺ T Cell Proliferation and Cytokine Production but Is Not Required for Tuning T Cell Reactivity in Adaptive Tolerance

Manabu Inobe, Ronald H. Schwartz

J Immunol (2004) 173 (12): 7239–7248.

https://doi.org/10.4049/jimmunol.173.12.7239

Published: 15 December 2004

View article titled, CTLA-4 Engagement Acts as a Brake on CD4+ T Cell Proliferation and Cytokine Production but Is Not Required for Tuning T Cell Reactivity in Adaptive Tolerance

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Journal Articles

IL-2 Secretion by CD4⁺ T Cells In Vivo Is Rapid, Transient, and Influenced by TCR-Specific Competition

Dorothy K. Sojka, Denis Bruniquel, Ronald H. Schwartz, Nevil J. Singh

J Immunol (2004) 172 (10): 6136–6143.

https://doi.org/10.4049/jimmunol.172.10.6136

Published: 15 May 2004

View article titled, IL-2 Secretion by CD4+ T Cells In Vivo Is Rapid, Transient, and Influenced by TCR-Specific Competition

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Journal Articles

Smad3 Is Essential for TGF-β1 to Suppress IL-2 Production and TCR-Induced Proliferation, but Not IL-2-Induced Proliferation

Susan C. McKarns, Ronald H. Schwartz, Norbert E. Kaminski

J Immunol (2004) 172 (7): 4275–4284.

https://doi.org/10.4049/jimmunol.172.7.4275

Published: 01 April 2004

View article titled, Smad3 Is Essential for TGF-β1 to Suppress IL-2 Production and TCR-Induced Proliferation, but Not IL-2-Induced Proliferation

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Journal Articles

Adaptive Tolerance of CD4⁺ T Cells In Vivo: Multiple Thresholds in Response to a Constant Level of Antigen Presentation

Corinne Tanchot, Daniel L. Barber, Lynda Chiodetti, Ronald H. Schwartz

J Immunol (2001) 167 (4): 2030–2039.

https://doi.org/10.4049/jimmunol.167.4.2030

Published: 15 August 2001

View article titled, Adaptive Tolerance of CD4+ T Cells In Vivo: Multiple Thresholds in Response to a Constant Level of Antigen Presentation

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Journal Articles

Epithelial Cell-Specific Laminin 5 Is Required for Survival of Early Thymocytes

Moon Gyo Kim, Gwanghee Lee, Suk-Keun Lee, Martijn Lolkema, Jeongbin Yim, Seung H. Hong, Ronald H. Schwartz

J Immunol (2000) 165 (1): 192–201.

https://doi.org/10.4049/jimmunol.165.1.192

Published: 01 July 2000

View article titled, Epithelial Cell-Specific Laminin 5 Is Required for Survival of Early Thymocytes

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Journal Articles

Distinct Requirements for C-C Chemokine and IL-2 Production by Naive, Previously Activated, and Anergic T Cells

Cara G. Lerner, Maureen R. Horton, Ronald H. Schwartz, Jonathan D. Powell

J Immunol (2000) 164 (8): 3996–4002.

https://doi.org/10.4049/jimmunol.164.8.3996

Published: 15 April 2000

View article titled, Distinct Requirements for C-C Chemokine and IL-2 Production by Naive, Previously Activated, and Anergic T Cells

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Journal Articles

A Putative 12 Transmembrane Domain Cotransporter Expressed in Thymic Cortical Epithelial Cells

Moon Gyo Kim, Francis A. Flomerfelt, Kee-Nyung Lee, Chuan Chen, Ronald H. Schwartz

J Immunol (2000) 164 (6): 3185–3192.

https://doi.org/10.4049/jimmunol.164.6.3185

Published: 15 March 2000

View article titled, A Putative 12 Transmembrane Domain Cotransporter Expressed in Thymic Cortical Epithelial Cells

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Journal Articles

The −180 Site of the IL-2 Promoter Is the Target of CREB/CREM Binding in T Cell Anergy

Jonathan D. Powell, Cara G. Lerner, Gerald R. Ewoldt, Ronald H. Schwartz

J Immunol (1999) 163 (12): 6631–6639.

https://doi.org/10.4049/jimmunol.163.12.6631

Published: 15 December 1999

View article titled, The −180 Site of the IL-2 Promoter Is the Target of CREB/CREM Binding in T Cell Anergy

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Journal Articles

The Destabilization of IL-2 mRNA by a Premature Stop Codon and Its Differential Stabilization by Trans-Acting Inhibitors of Protein Synthesis Do Not Support a Role for Active Translation in mRNA Stability

Jack A. Ragheb, Mary Deen, Ronald H. Schwartz

J Immunol (1999) 163 (6): 3321–3330.

https://doi.org/10.4049/jimmunol.163.6.3321

Published: 15 September 1999

View article titled, The Destabilization of IL-2 mRNA by a Premature Stop Codon and Its Differential Stabilization by Trans-Acting Inhibitors of Protein Synthesis Do Not Support a Role for Active Translation in mRNA Stability

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Journal Articles

CD28-Mediated Regulation of mRNA Stability Requires Sequences Within the Coding Region of the IL-2 mRNA

Jack A. Ragheb, Mary Deen, Ronald H. Schwartz

J Immunol (1999) 163 (1): 120–129.

https://doi.org/10.4049/jimmunol.163.1.120

Published: 01 July 1999

View article titled, CD28-Mediated Regulation of mRNA Stability Requires Sequences Within the Coding Region of the IL-2 mRNA

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Journal Articles

Inhibition of Cell Cycle Progression by Rapamycin Induces T Cell Clonal Anergy Even in the Presence of Costimulation

Jonathan D. Powell, Cara G. Lerner, Ronald H. Schwartz

J Immunol (1999) 162 (5): 2775–2784.

https://doi.org/10.4049/jimmunol.162.5.2775

Published: 01 March 1999

View article titled, Inhibition of Cell Cycle Progression by Rapamycin Induces T Cell Clonal Anergy Even in the Presence of Costimulation

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NARROW

Two-Step Binding of Transcription Factors Causes Sequential Chromatin Structural Changes at the Activated IL-2 Promoter

Impairment of Immunological Synapse Formation in Adaptively Tolerant T Cells

Pillars Article: Antigen Presentation by Chemically Modified Splenocytes Induces Antigen-Specific T Cell Unresponsiveness In Vitro and In Vivo. J. Exp. Med. 1987. 165: 302–319

Biphasic Regulation of Il2 Transcription in CD4⁺ T Cells: Roles for TNF-α Receptor Signaling and Chromatin Structure

TLR Ligands Differentially Modulate T Cell Responses to Acute and Chronic Antigen Presentation

Dual Effects of Sprouty1 on TCR Signaling Depending on the Differentiation State of the T Cell

Adaptive Tolerance and Clonal Anergy Are Distinct Biochemical States

Distinct Effects of TGF-β1 on CD4⁺ and CD8⁺ T Cell Survival, Division, and IL-2 Production: A Role for T Cell Intrinsic Smad3

A Distinct Region of the Murine IFN-γ Promoter Is Hypomethylated from Early T Cell Development through Mature Naive and Th1 Cell Differentiation, but Is Hypermethylated in Th2 Cells

CTLA-4 Engagement Acts as a Brake on CD4⁺ T Cell Proliferation and Cytokine Production but Is Not Required for Tuning T Cell Reactivity in Adaptive Tolerance

IL-2 Secretion by CD4⁺ T Cells In Vivo Is Rapid, Transient, and Influenced by TCR-Specific Competition

Smad3 Is Essential for TGF-β1 to Suppress IL-2 Production and TCR-Induced Proliferation, but Not IL-2-Induced Proliferation

Adaptive Tolerance of CD4⁺ T Cells In Vivo: Multiple Thresholds in Response to a Constant Level of Antigen Presentation

Epithelial Cell-Specific Laminin 5 Is Required for Survival of Early Thymocytes

Distinct Requirements for C-C Chemokine and IL-2 Production by Naive, Previously Activated, and Anergic T Cells

A Putative 12 Transmembrane Domain Cotransporter Expressed in Thymic Cortical Epithelial Cells

The −180 Site of the IL-2 Promoter Is the Target of CREB/CREM Binding in T Cell Anergy

The Destabilization of IL-2 mRNA by a Premature Stop Codon and Its Differential Stabilization by Trans-Acting Inhibitors of Protein Synthesis Do Not Support a Role for Active Translation in mRNA Stability

CD28-Mediated Regulation of mRNA Stability Requires Sequences Within the Coding Region of the IL-2 mRNA

Inhibition of Cell Cycle Progression by Rapamycin Induces T Cell Clonal Anergy Even in the Presence of Costimulation

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