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Ruslan Medzhitov
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Journal Articles

Macrophages restrain pathological interferon responses during viral respiratory infection

Patricia Rodriguez-Morales, Daisy Hoagland, Alexander Mann, Shuang Yu, Alicia Lai, Alan Baez Vazquez, Ruslan Medzhitov, Ruth Franklin
Journal: The Journal of Immunology
J Immunol (2024) 212 (1_Supplement): 0536_5144.
https://doi.org/10.4049/jimmunol.212.supp.0536.5144
Published: 01 May 2024
View article titled, Macrophages restrain pathological interferon responses during viral respiratory infection
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Journal Articles

Proteostasis maintenance by macrophage trogocytosis

Yoshitaka Kimura, Naomi Philip, Arun Chavan, Ruslan Medzhitov
Journal: The Journal of Immunology
J Immunol (2024) 212 (1_Supplement): 1318_4183.
https://doi.org/10.4049/jimmunol.212.supp.1318.4183
Published: 01 May 2024
View article titled, Proteostasis maintenance by macrophage trogocytosis
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Journal Articles

Microenvironment controls inflammatory response in macrophages

Xu Zhou, Scott D Pope, Ruslan Medzhitov
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 111.03.
https://doi.org/10.4049/jimmunol.206.Supp.111.03
Published: 01 May 2021
View article titled, Microenvironment controls inflammatory response in macrophages
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Journal Articles

Integrated Innate Mechanisms Involved in Airway Allergic Inflammation to the Serine Protease Subtilisin

Esther Florsheim, Shuang Yu, Ivan Bragatto, Lucas Faustino, Eliane Gomes, Rodrigo N. Ramos, José Alexandre M. Barbuto, Ruslan Medzhitov, Momtchilo Russo
Journal: The Journal of Immunology
J Immunol (2015) 194 (10): 4621–4630.
https://doi.org/10.4049/jimmunol.1402493
Published: 15 May 2015
View article titled, Integrated Innate Mechanisms Involved in Airway Allergic Inflammation to the Serine Protease Subtilisin
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Includes: Supplementary data
Journal Articles

Pattern Recognition Theory and the Launch of Modern Innate Immunity

In Special Collection:
Pillars of Immunology
Ruslan Medzhitov
Journal: The Journal of Immunology
J Immunol (2013) 191 (9): 4473–4474.
https://doi.org/10.4049/jimmunol.1302427
Published: 01 November 2013
View article titled, Pattern Recognition Theory and the Launch of Modern Innate Immunity
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Journal Articles

MyD88 Expression on Villin Inhibits Obesity in High Fat Diet Mice (120.5)

Chen Chao, Yufei Xiang, Yipeng Wang, Jian Peng, Youjia Hu, Ningwen Tai, Namiko Hoshi, Zhiguang Zhou, Ruslan Medzhitov, Li Wen
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 120.5.
https://doi.org/10.4049/jimmunol.188.Supp.120.5
Published: 01 May 2012
View article titled, MyD88 Expression on Villin Inhibits Obesity in High Fat Diet Mice (120.5)
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Journal Articles

Abnormal Trafficking and Degradation of TLR4 Underlie the Elevated Inflammatory Response in Cystic Fibrosis

Emanuela M. Bruscia, Ping-Xia Zhang, Ayano Satoh, Christina Caputo, Ruslan Medzhitov, Ambika Shenoy, Marie E. Egan, Diane S. Krause
Journal: The Journal of Immunology
J Immunol (2011) 186 (12): 6990–6998.
https://doi.org/10.4049/jimmunol.1100396
Published: 15 June 2011
View article titled, Abnormal Trafficking and Degradation of TLR4 Underlie the Elevated Inflammatory Response in Cystic Fibrosis
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Includes: Supplementary data
Journal Articles

Airway Epithelial MyD88 Restores Control of Pseudomonas aeruginosa Murine Infection via an IL-1–Dependent Pathway

Lilia A. Mijares, Tamding Wangdi, Caroline Sokol, Robert Homer, Ruslan Medzhitov, Barbara I. Kazmierczak
Journal: The Journal of Immunology
J Immunol (2011) 186 (12): 7080–7088.
https://doi.org/10.4049/jimmunol.1003687
Published: 15 June 2011
View article titled, Airway Epithelial MyD88 Restores Control of <em>Pseudomonas aeruginosa</em> Murine Infection via an IL-1–Dependent Pathway
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Includes: Supplementary data
Journal Articles

Age-Associated Defect in Human TLR-1/2 Function

David van Duin, Subhasis Mohanty, Venetta Thomas, Sandra Ginter, Ruth R. Montgomery, Erol Fikrig, Heather G. Allore, Ruslan Medzhitov, Albert C. Shaw
Journal: The Journal of Immunology
J Immunol (2007) 178 (2): 970–975.
https://doi.org/10.4049/jimmunol.178.2.970
Published: 15 January 2007
View article titled, Age-Associated Defect in Human TLR-1/2 Function
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Journal Articles

TLR4 Up-Regulation at Protein or Gene Level Is Pathogenic for Lupus-Like Autoimmune Disease

Bei Liu, Yi Yang, Jie Dai, Ruslan Medzhitov, Marina A. Freudenberg, Ping L. Zhang, Zihai Li
Journal: The Journal of Immunology
J Immunol (2006) 177 (10): 6880–6888.
https://doi.org/10.4049/jimmunol.177.10.6880
Published: 15 November 2006
View article titled, TLR4 Up-Regulation at Protein or Gene Level Is Pathogenic for Lupus-Like Autoimmune Disease
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Journal Articles

Cutting Edge: TLR4 Deficiency Confers Susceptibility to Lethal Oxidant Lung Injury

Xuchen Zhang, Peiying Shan, Salman Qureshi, Robert Homer, Ruslan Medzhitov, Paul W. Noble, Patty J. Lee
Journal: The Journal of Immunology
J Immunol (2005) 175 (8): 4834–4838.
https://doi.org/10.4049/jimmunol.175.8.4834
Published: 15 October 2005
View article titled, Cutting Edge: TLR4 Deficiency Confers Susceptibility to Lethal Oxidant Lung Injury
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Journal Articles

Cutting Edge: MyD88 Is Required for Resistance to Toxoplasma gondii Infection and Regulates Parasite-Induced IL-12 Production by Dendritic Cells

Charles A. Scanga, Julio Aliberti, Dragana Jankovic, Florence Tilloy, Soumaya Bennouna, Eric Y. Denkers, Ruslan Medzhitov, Alan Sher
Journal: The Journal of Immunology
J Immunol (2002) 168 (12): 5997–6001.
https://doi.org/10.4049/jimmunol.168.12.5997
Published: 15 June 2002
View article titled, Cutting Edge: MyD88 Is Required for Resistance to <em>Toxoplasma gondii</em> Infection and Regulates Parasite-Induced IL-12 Production by Dendritic Cells
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Journal Articles

Regulation of Toll-Like Receptor 4 Expression in the Lung Following Hemorrhagic Shock and Lipopolysaccharide

Jie Fan, Andras Kapus, Philip A. Marsden, Yue Hua Li, George Oreopoulos, John C. Marshall, Stefan Frantz, Ralph A. Kelly, Ruslan Medzhitov, Ori D. Rotstein
Journal: The Journal of Immunology
J Immunol (2002) 168 (10): 5252–5259.
https://doi.org/10.4049/jimmunol.168.10.5252
Published: 15 May 2002
View article titled, Regulation of Toll-Like Receptor 4 Expression in the Lung Following Hemorrhagic Shock and Lipopolysaccharide
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Journal Articles

Large-Scale Culture and Selective Maturation of Human Langerhans Cells from Granulocyte Colony-Stimulating Factor-Mobilized CD34+ Progenitors

Evelina Gatti, Mark A. Velleca, Barbara C. Biedermann, Weilie Ma, Juli Unternaehrer, Melanie W. Ebersold, Ruslan Medzhitov, Jordan S. Pober, Ira Mellman
Journal: The Journal of Immunology
J Immunol (2000) 164 (7): 3600–3607.
https://doi.org/10.4049/jimmunol.164.7.3600
Published: 01 April 2000
View article titled, Large-Scale Culture and Selective Maturation of Human Langerhans Cells from Granulocyte Colony-Stimulating Factor-Mobilized CD34<sup>+</sup> Progenitors
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Journal Articles

α(1,3)-Fucosyltransferase VII and α(2,3)-Sialyltransferase IV Are Up-Regulated in Activated CD4 T Cells and Maintained After Their Differentiation into Th1 and Migration into Inflammatory Sites

J. Magarian Blander, Irene Visintin, Charles A. Janeway, Jr., Ruslan Medzhitov
Journal: The Journal of Immunology
J Immunol (1999) 163 (7): 3746–3752.
https://doi.org/10.4049/jimmunol.163.7.3746
Published: 01 October 1999
View article titled, α(1,3)-Fucosyltransferase VII and α(2,3)-Sialyltransferase IV Are Up-Regulated in Activated CD4 T Cells and Maintained After Their Differentiation into Th1 and Migration into Inflammatory Sites
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