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Søren R. Paludan
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Journal Articles

SARS-CoV-2 Neutralizing Antibody Responses towards Full-Length Spike Protein and the Receptor-Binding Domain

In Special Collection:
COVID-19, SARS, and MERS Articles
Rafael Bayarri-Olmos, Manja Idorn, Anne Rosbjerg, Laura Pérez-Alós, Cecilie Bo Hansen, Laust Bruun Johnsen, Charlotte Helgstrand, Franziska Zosel, Jais Rose Bjelke, Fredrik Kryh Öberg, Max Søgaard, Søren R. Paludan, Theresa Bak-Thomsen, Joseph G. Jardine, Mikkel-Ole Skjoedt, Peter Garred
Journal: The Journal of Immunology
J Immunol (2021) 207 (3): 878–887.
https://doi.org/10.4049/jimmunol.2100272
Published: 01 August 2021
View article titled, SARS-CoV-2 Neutralizing Antibody Responses towards Full-Length Spike Protein and the Receptor-Binding Domain
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Includes: Supplementary data
Journal Articles

Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4

Kristian Juul-Madsen, Per Qvist, Kirstine L. Bendtsen, Annette E. Langkilde, Bente Vestergaard, Kenneth A. Howard, Martxel Dehesa-Etxebeste, Søren R. Paludan, Gregers Rom Andersen, Poul Henning Jensen, Daniel E. Otzen, Marina Romero-Ramos, Thomas Vorup-Jensen
Journal: The Journal of Immunology
J Immunol (2020) 204 (5): 1345–1361.
https://doi.org/10.4049/jimmunol.1900494
Published: 01 March 2020
View article titled, Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4
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Includes: Supplementary data
Journal Articles

Cutting Edge: Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2–Induced IFN-β Expression

Kristina Eriksson, Alexandra Svensson, Alon S. Hait, Kerstin Schlüter, Petra Tunbäck, Inger Nordström, Leonid Padyukov, Jan-Åke Liljeqvist, Trine H. Mogensen, Søren R. Paludan
Journal: The Journal of Immunology
J Immunol (2017) 199 (8): 2613–2617.
https://doi.org/10.4049/jimmunol.1700385
Published: 15 October 2017
View article titled, Cutting Edge: Genetic Association between IFI16 Single Nucleotide Polymorphisms and Resistance to Genital Herpes Correlates with IFI16 Expression Levels and HSV-2–Induced IFN-β Expression
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Includes: Supplementary data
Journal Articles

Evasion of Innate Cytosolic DNA Sensing by a Gammaherpesvirus Facilitates Establishment of Latent Infection

Chenglong Sun, Stefan A. Schattgen, Prapaporn Pisitkun, Joan P. Jorgensen, Adam T. Hilterbrand, Lucas J. Wang, John A. West, Kathrine Hansen, Kristy A. Horan, Martin R. Jakobsen, Peter O’Hare, Heiko Adler, Ren Sun, Hidde L. Ploegh, Blossom Damania, Jason W. Upton, Katherine A. Fitzgerald, Søren R. Paludan
Journal: The Journal of Immunology
J Immunol (2015) 194 (4): 1819–1831.
https://doi.org/10.4049/jimmunol.1402495
Published: 15 February 2015
View article titled, Evasion of Innate Cytosolic DNA Sensing by a Gammaherpesvirus Facilitates Establishment of Latent Infection
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Includes: Supplementary data
Journal Articles

TRAM Is Required for TLR2 Endosomal Signaling to Type I IFN Induction

Julianne Stack, Sarah L. Doyle, Dympna J. Connolly, Line S. Reinert, Kate M. O’Keeffe, Rachel M. McLoughlin, Søren R. Paludan, Andrew G. Bowie
Journal: The Journal of Immunology
J Immunol (2014) 193 (12): 6090–6102.
https://doi.org/10.4049/jimmunol.1401605
Published: 15 December 2014
View article titled, TRAM Is Required for TLR2 Endosomal Signaling to Type I IFN Induction
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Journal Articles

Inflammatory Cytokines Break Down Intrinsic Immunological Tolerance of Human Primary Keratinocytes to Cytosolic DNA

Srikanth Chiliveru, Stine H. Rahbek, Simon K. Jensen, Sofie E. Jørgensen, Sara K. Nissen, Stig H. Christiansen, Trine H. Mogensen, Martin R. Jakobsen, Lars Iversen, Claus Johansen, Søren R. Paludan
Journal: The Journal of Immunology
J Immunol (2014) 192 (5): 2395–2404.
https://doi.org/10.4049/jimmunol.1302120
Published: 01 March 2014
View article titled, Inflammatory Cytokines Break Down Intrinsic Immunological Tolerance of Human Primary Keratinocytes to Cytosolic DNA
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Includes: Supplementary data
Journal Articles

Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors

Kristy A. Horan, Kathrine Hansen, Martin R. Jakobsen, Christian K. Holm, Stine Søby, Leonie Unterholzner, Mikayla Thompson, John A. West, Marie B. Iversen, Simon B. Rasmussen, Svend Ellermann-Eriksen, Evelyn Kurt-Jones, Santo Landolfo, Blossom Damania, Jesper Melchjorsen, Andrew G. Bowie, Katherine A. Fitzgerald, Søren R. Paludan
Journal: The Journal of Immunology
J Immunol (2013) 190 (5): 2311–2319.
https://doi.org/10.4049/jimmunol.1202749
Published: 01 March 2013
View article titled, Proteasomal Degradation of Herpes Simplex Virus Capsids in Macrophages Releases DNA to the Cytosol for Recognition by DNA Sensors
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Includes: Supplementary data
Journal Articles

MyD88 Drives the IFN-β Response to Lactobacillus acidophilus in Dendritic Cells through a Mechanism Involving IRF1, IRF3, and IRF7

Gudrun Weiss, Kristina Maaetoft-Udsen, Sebastian A. Stifter, Paul Hertzog, Stanislas Goriely, Allan R. Thomsen, Søren R. Paludan, Hanne Frøkiær
Journal: The Journal of Immunology
J Immunol (2012) 189 (6): 2860–2868.
https://doi.org/10.4049/jimmunol.1103491
Published: 15 September 2012
View article titled, MyD88 Drives the IFN-β Response to <em>Lactobacillus acidophilus</em> in Dendritic Cells through a Mechanism Involving IRF1, IRF3, and IRF7
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Includes: Supplementary data
Journal Articles

Activation of Autophagy by α-Herpesviruses in Myeloid Cells Is Mediated by Cytoplasmic Viral DNA through a Mechanism Dependent on Stimulator of IFN Genes

Simon B. Rasmussen, Kristy A. Horan, Christian K. Holm, Amanda J. Stranks, Thomas C. Mettenleiter, A. Katharina Simon, Søren B. Jensen, Frazer J. Rixon, Bin He, Søren R. Paludan
Journal: The Journal of Immunology
J Immunol (2011) 187 (10): 5268–5276.
https://doi.org/10.4049/jimmunol.1100949
Published: 15 November 2011
View article titled, Activation of Autophagy by α-Herpesviruses in Myeloid Cells Is Mediated by Cytoplasmic Viral DNA through a Mechanism Dependent on Stimulator of IFN Genes
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Journal Articles

TLR3 Ligand Polyinosinic:Polycytidylic Acid Induces IL-17A and IL-21 Synthesis in Human Th Cells

Christian K. Holm, Charlotte C. Petersen, Malene Hvid, Line Petersen, Søren R. Paludan, Bent Deleuran, Marianne Hokland
Journal: The Journal of Immunology
J Immunol (2009) 183 (7): 4422–4431.
https://doi.org/10.4049/jimmunol.0804318
Published: 01 October 2009
View article titled, TLR3 Ligand Polyinosinic:Polycytidylic Acid Induces IL-17A and IL-21 Synthesis in Human Th Cells
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Journal Articles

TLR2 and TLR9 Synergistically Control Herpes Simplex Virus Infection in the Brain

Louise N. Sørensen, Line S. Reinert, Lene Malmgaard, Christina Bartholdy, Allan R. Thomsen, Søren R. Paludan
Journal: The Journal of Immunology
J Immunol (2008) 181 (12): 8604–8612.
https://doi.org/10.4049/jimmunol.181.12.8604
Published: 15 December 2008
View article titled, TLR2 and TLR9 Synergistically Control Herpes Simplex Virus Infection in the Brain
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Journal Articles

An Important Role for Type III Interferon (IFN-λ/IL-28) in TLR-Induced Antiviral Activity

Nina Ank, Marie B. Iversen, Christina Bartholdy, Peter Staeheli, Rune Hartmann, Uffe B. Jensen, Frederik Dagnaes-Hansen, Allan R. Thomsen, Zhi Chen, Harald Haugen, Kevin Klucher, Søren R. Paludan
Journal: The Journal of Immunology
J Immunol (2008) 180 (4): 2474–2485.
https://doi.org/10.4049/jimmunol.180.4.2474
Published: 15 February 2008
View article titled, An Important Role for Type III Interferon (IFN-λ/IL-28) in TLR-Induced Antiviral Activity
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Journal Articles

p38 MAPK Autophosphorylation Drives Macrophage IL-12 Production during Intracellular Infection

Leesun Kim, Laura Del Rio, Barbara A. Butcher, Trine H. Mogensen, Søren R. Paludan, Richard A. Flavell, Eric Y. Denkers
Journal: The Journal of Immunology
J Immunol (2005) 174 (7): 4178–4184.
https://doi.org/10.4049/jimmunol.174.7.4178
Published: 01 April 2005
View article titled, p38 MAPK Autophosphorylation Drives Macrophage IL-12 Production during Intracellular Infection
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Journal Articles

Viral Activation of Macrophages through TLR-Dependent and -Independent Pathways

Lene Malmgaard, Jesper Melchjorsen, Andrew G. Bowie, Søren C. Mogensen, Søren R. Paludan
Journal: The Journal of Immunology
J Immunol (2004) 173 (11): 6890–6898.
https://doi.org/10.4049/jimmunol.173.11.6890
Published: 01 December 2004
View article titled, Viral Activation of Macrophages through TLR-Dependent and -Independent Pathways
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Journal Articles

Activation of NF-κB in Virus-Infected Macrophages Is Dependent on Mitochondrial Oxidative Stress and Intracellular Calcium: Downstream Involvement of the Kinases TGF-β-Activated Kinase 1, Mitogen-Activated Kinase/Extracellular Signal-Regulated Kinase Kinase 1, and IκB Kinase

Trine H. Mogensen, Jesper Melchjorsen, Per Höllsberg, Søren R. Paludan
Journal: The Journal of Immunology
J Immunol (2003) 170 (12): 6224–6233.
https://doi.org/10.4049/jimmunol.170.12.6224
Published: 15 June 2003
View article titled, Activation of NF-κB in Virus-Infected Macrophages Is Dependent on Mitochondrial Oxidative Stress and Intracellular Calcium: Downstream Involvement of the Kinases TGF-β-Activated Kinase 1, Mitogen-Activated Kinase/Extracellular Signal-Regulated Kinase Kinase 1, and IκB Kinase
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Expression of TNF-α by Herpes Simplex Virus-Infected Macrophages Is Regulated by a Dual Mechanism: Transcriptional Regulation by NF-κB and Activating Transcription Factor 2/Jun and Translational Regulation Through the AU-Rich Region of the 3′ Untranslated Region

Søren R. Paludan, Svend Ellermann-Eriksen, Veronique Kruys, Søren C. Mogensen
Journal: The Journal of Immunology
J Immunol (2001) 167 (4): 2202–2208.
https://doi.org/10.4049/jimmunol.167.4.2202
Published: 15 August 2001
View article titled, Expression of TNF-α by Herpes Simplex Virus-Infected Macrophages Is Regulated by a Dual Mechanism: Transcriptional Regulation by NF-κB and Activating Transcription Factor 2/Jun and Translational Regulation Through the AU-Rich Region of the 3′ Untranslated Region
Open the PDF for Expression of TNF-α by Herpes Simplex Virus-Infected Macrophages Is Regulated by a Dual Mechanism: Transcriptional Regulation by NF-κB and Activating Transcription Factor 2/Jun and Translational Regulation Through the AU-Rich Region of the 3′ Untranslated Region in another window
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