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Journal Articles

T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways

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Kohei Hosokawa, Sachiko Kajigaya, Keyvan Keyvanfar, Wangmin Qiao, Yanling Xie, Danielle M. Townsley, Xingmin Feng, Neal S. Young
Journal: The Journal of Immunology
J Immunol (2017) 199 (2): 477–488.
https://doi.org/10.4049/jimmunol.1601299
Published: 15 July 2017
View articletitled, T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways
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Includes: Supplementary data
Journal Articles

B cell response to parvovirus B19 despite abnormal splenic architecture and cytokine/chemokine profiles in patients and animal models with sickle cell disease (SCD)

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Rhiannon Penkert, Jane S Hankins, Philip R Dormitzer, Ethan C Settembre, Li Tang, Yilun Sun, Paul G Thomas, Sumana Chandramouli, Randall Hayden, Susan Wong, Sherri L Surman, Robert E Sealy, Jason Rosch, Jola Dowdy, Neal S Young, Julia L Hurwitz
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 122.5.
https://doi.org/10.4049/jimmunol.198.Supp.122.5
Published: 01 May 2017
View articletitled, B cell response to parvovirus B19 despite abnormal splenic architecture and cytokine/chemokine profiles in patients and animal models with sickle cell disease (SCD)
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Journal Articles

Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia

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Kohei Hosokawa, Pawel Muranski, Xingmin Feng, Danielle M. Townsley, Baoying Liu, Jared Knickelbein, Keyvan Keyvanfar, Bogdan Dumitriu, Sawa Ito, Sachiko Kajigaya, James G. Taylor, VI, Mariana J. Kaplan, Robert B. Nussenblatt, A. John Barrett, John O’Shea, Neal S. Young
Journal: The Journal of Immunology
J Immunol (2016) 196 (4): 1568–1578.
https://doi.org/10.4049/jimmunol.1501739
Published: 15 February 2016
View articletitled, Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia
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Includes: Supplementary data
Journal Articles

Enhancer Turnover Is Associated with a Divergent Transcriptional Response to Glucocorticoid in Mouse and Human Macrophages

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Alasdair W. Jubb, Robert S. Young, David A. Hume, Wendy A. Bickmore
Journal: The Journal of Immunology
J Immunol (2016) 196 (2): 813–822.
https://doi.org/10.4049/jimmunol.1502009
Published: 15 January 2016
View articletitled, Enhancer Turnover Is Associated with a Divergent Transcriptional Response to Glucocorticoid in Mouse and Human Macrophages
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Includes: Supplementary data
Journal Articles

Thymic Damage, Impaired Negative Selection, and Development of Chronic Graft-versus-Host Disease Caused by Donor CD4+ and CD8+ T Cells

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Tao Wu, James S. Young, Heather Johnston, Xiong Ni, Ruishu Deng, Jeremy Racine, Miao Wang, Audrey Wang, Ivan Todorov, Jianmin Wang, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2013) 191 (1): 488–499.
https://doi.org/10.4049/jimmunol.1300657
Published: 01 July 2013
View articletitled, Thymic Damage, Impaired Negative Selection, and Development of Chronic Graft-versus-Host Disease Caused by Donor CD4+ and CD8+ T Cells
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Includes: Supplementary data
Journal Articles

Donor B Cells in Transplants Augment Clonal Expansion and Survival of Pathogenic CD4+ T Cells That Mediate Autoimmune-like Chronic Graft-versus-Host Disease

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James S. Young, Tao Wu, Yuhong Chen, Dongchang Zhao, Hongjun Liu, Tangsheng Yi, Heather Johnston, Jeremy Racine, Xiaofan Li, Audrey Wang, Ivan Todorov, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2012) 189 (1): 222–233.
https://doi.org/10.4049/jimmunol.1200677
Published: 01 July 2012
View articletitled, Donor B Cells in Transplants Augment Clonal Expansion and Survival of Pathogenic CD4+ T Cells That Mediate Autoimmune-like Chronic Graft-versus-Host Disease
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Includes: Supplementary data
Journal Articles

Host APCs Augment In Vivo Expansion of Donor Natural Regulatory T Cells via B7H1/B7.1 in Allogeneic Recipients

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Tangsheng Yi, Xiaofan Li, Sheng Yao, Lin Wang, Yuhong Chen, Dongchang Zhao, Heather F. Johnston, James S. Young, Hongjun Liu, Ivan Todorov, Stephen J. Forman, Lieping Chen, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2011) 186 (5): 2739–2749.
https://doi.org/10.4049/jimmunol.1002939
Published: 01 March 2011
View articletitled, Host APCs Augment In Vivo Expansion of Donor Natural Regulatory T Cells via B7H1/B7.1 in Allogeneic Recipients
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Includes: Supplementary data
Journal Articles

Alloimmune Response Results in Expansion of Autoreactive Donor CD4+ T Cells in Transplants That Can Mediate Chronic Graft-versus-Host Disease

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Dongchang Zhao, James S. Young, Yu-Hong Chen, Elizabeth Shen, Tangsheng Yi, Ivan Todorov, Peiguo G. Chu, Stephen J. Forman, Defu Zeng
Journal: The Journal of Immunology
J Immunol (2011) 186 (2): 856–868.
https://doi.org/10.4049/jimmunol.1002195
Published: 15 January 2011
View articletitled, Alloimmune Response Results in Expansion of Autoreactive Donor CD4+ T Cells in Transplants That Can Mediate Chronic Graft-versus-Host Disease
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Includes: Supplementary data
Journal Articles

CD40 Ligand-Induced Carcinoma Cell Death: A Balance between Activation of TNFR-Associated Factor (TRAF) 3-Dependent Death Signals and Suppression of TRAF6-Dependent Survival Signals

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Taha Elmetwali, Lawrence S. Young, Daniel H. Palmer
Journal: The Journal of Immunology
J Immunol (2010) 184 (2): 1111–1120.
https://doi.org/10.4049/jimmunol.0900528
Published: 27 December 2009
View articletitled, CD40 Ligand-Induced Carcinoma Cell Death: A Balance between Activation of TNFR-Associated Factor (TRAF) 3-Dependent Death Signals and Suppression of TRAF6-Dependent Survival Signals
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Journal Articles

Lymphocytes with Aberrant Expression of Fas or Fas Ligand Attenuate Immune Bone Marrow Failure in a Mouse Model

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Stephanie O. Omokaro, Marie J. Desierto, Michael A. Eckhaus, Felicia M. Ellison, Jichun Chen, Neal S. Young
Journal: The Journal of Immunology
J Immunol (2009) 182 (6): 3414–3422.
https://doi.org/10.4049/jimmunol.0801430
Published: 15 March 2009
View articletitled, Lymphocytes with Aberrant Expression of Fas or Fas Ligand Attenuate Immune Bone Marrow Failure in a Mouse Model
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Journal Articles

CD154 Tone Sets the Signaling Pathways and Transcriptome Generated in Model CD40-Pluricompetent L3055 Burkitt’s Lymphoma Cells

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Ross Stewart, Wenbin Wei, Anita Challa, Richard J. Armitage, John R. Arrand, Martin Rowe, Lawrence S. Young, Aristides Eliopoulos, John Gordon
Journal: The Journal of Immunology
J Immunol (2007) 179 (5): 2705–2712.
https://doi.org/10.4049/jimmunol.179.5.2705
Published: 01 September 2007
View articletitled, CD154 Tone Sets the Signaling Pathways and Transcriptome Generated in Model CD40-Pluricompetent L3055 Burkitt’s Lymphoma Cells
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Includes: Supplementary data
Journal Articles

Minor Antigen H60-Mediated Aplastic Anemia Is Ameliorated by Immunosuppression and the Infusion of Regulatory T Cells

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Jichun Chen, Felicia M. Ellison, Michael A. Eckhaus, Aleah L. Smith, Keyvan Keyvanfar, Rodrigo T. Calado, Neal S. Young
Journal: The Journal of Immunology
J Immunol (2007) 178 (7): 4159–4168.
https://doi.org/10.4049/jimmunol.178.7.4159
Published: 01 April 2007
View articletitled, Minor Antigen H60-Mediated Aplastic Anemia Is Ameliorated by Immunosuppression and the Infusion of Regulatory T Cells
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Journal Articles

Activation of CD40 in Cervical Carcinoma Cells Facilitates CTL Responses and Augments Chemotherapy-Induced Apoptosis

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Seran C. Hill, Sarah J. Youde, Stephen Man, Glyn R. Teale, Amanda J. Baxendale, Andrew Hislop, Clare C. Davies, David M. Luesley, Anna M. Blom, Alan B. Rickinson, Lawrence S. Young, Aristides G. Eliopoulos
Journal: The Journal of Immunology
J Immunol (2005) 174 (1): 41–50.
https://doi.org/10.4049/jimmunol.174.1.41
Published: 01 January 2005
View articletitled, Activation of CD40 in Cervical Carcinoma Cells Facilitates CTL Responses and Augments Chemotherapy-Induced Apoptosis
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Journal Articles

Molecular Analysis of TCR Clonotypes in LGL: A Clonal Model for Polyclonal Responses

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Christine L. O’Keefe, Magdalena Plasilova, Marcin Wlodarski, Antonio M. Risitano, Alexander R. Rodriguez, Evan Howe, Neal S. Young, Eric Hsi, Jaroslaw P. Maciejewski
Journal: The Journal of Immunology
J Immunol (2004) 172 (3): 1960–1969.
https://doi.org/10.4049/jimmunol.172.3.1960
Published: 01 February 2004
View articletitled, Molecular Analysis of TCR Clonotypes in LGL: A Clonal Model for Polyclonal Responses
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Journal Articles

Inhibition of Metalloproteinase Cleavage Enhances the Cytotoxicity of Fas Ligand

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Pauline G. Knox, Anne E. Milner, Nicky K. Green, Aristides G. Eliopoulos, Lawrence S. Young
Journal: The Journal of Immunology
J Immunol (2003) 170 (2): 677–685.
https://doi.org/10.4049/jimmunol.170.2.677
Published: 15 January 2003
View articletitled, Inhibition of Metalloproteinase Cleavage Enhances the Cytotoxicity of Fas Ligand
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Journal Articles

Amino acid residues on the I-Ak alpha-chain required for the binding and stability of two antigenic peptides.

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C A Nelson, N Viner, S Young, S Petzold, C Benoist, D Mathis, E R Unanue
Journal: The Journal of Immunology
J Immunol (1996) 156 (1): 176–182.
https://doi.org/10.4049/jimmunol.156.1.176
Published: 01 January 1996
View articletitled, Amino acid residues on the I-Ak alpha-chain required for the binding and stability of two antigenic peptides.
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Journal Articles

HIV-1 suppression of hematopoiesis in vitro mediated by envelope glycoprotein and TNF-alpha.

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J P Maciejewski, F F Weichold, N S Young
Journal: The Journal of Immunology
J Immunol (1994) 153 (9): 4303–4310.
https://doi.org/10.4049/jimmunol.153.9.4303
Published: 01 November 1994
View articletitled, HIV-1 suppression of hematopoiesis in vitro mediated by envelope glycoprotein and TNF-alpha.
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Journal Articles

Natural killer cell-dependent mycobacteriostatic and mycobactericidal activity in human macrophages.

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L E Bermudez, L S Young
Journal: The Journal of Immunology
J Immunol (1991) 146 (1): 265–270.
https://doi.org/10.4049/jimmunol.146.1.265
Published: 01 January 1991
View articletitled, Natural killer cell-dependent mycobacteriostatic and mycobactericidal activity in human macrophages.
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Journal Articles

Treatment of experimental disseminated Mycobacterium avium complex infection in mice with recombinant IL-2 and tumor necrosis factor.

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L E Bermudez, P Stevens, P Kolonoski, M Wu, L S Young
Journal: The Journal of Immunology
J Immunol (1989) 143 (9): 2996–3000.
https://doi.org/10.4049/jimmunol.143.9.2996
Published: 01 November 1989
View articletitled, Treatment of experimental disseminated Mycobacterium avium complex infection in mice with recombinant IL-2 and tumor necrosis factor.
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Journal Articles

Tumor necrosis factor, alone or in combination with IL-2, but not IFN-gamma, is associated with macrophage killing of Mycobacterium avium complex.

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L E Bermudez, L S Young
Journal: The Journal of Immunology
J Immunol (1988) 140 (9): 3006–3013.
https://doi.org/10.4049/jimmunol.140.9.3006
Published: 01 May 1988
View articletitled, Tumor necrosis factor, alone or in combination with IL-2, but not IFN-gamma, is associated with macrophage killing of Mycobacterium avium complex.
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