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Journal Articles

Anti-CD11b antibody treatment suppresses the disease conditions in rheumatoid arthritis (RA)-prone, FcγRIIB-deficient mice

Kazuko Takahashi, Mareki Ohtsuji, Qingshun Lin, Hideki Okazaki, Hirofumi Amano, Hideo Yagita, Hiroyuki Nishimura, Sachiko Hirose
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 183.16.
https://doi.org/10.4049/jimmunol.202.Supp.183.16
Published: 01 May 2019
View article titled, Anti-CD11b antibody treatment suppresses the disease conditions in rheumatoid arthritis (RA)-prone, FcγRIIB-deficient mice
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Journal Articles

FcγRIIb on B Cells and Myeloid Cells Modulates B Cell Activation and Autoantibody Responses via Different but Synergistic Pathways in Lupus-Prone Yaa Mice

Qingshun Lin, Mareki Ohtsuji, Hirofumi Amano, Hiromichi Tsurui, Norihiro Tada, Ryota Sato, Hidehiro Fukuyama, Hiroyuki Nishimura, J. Sjef Verbeek, Sachiko Hirose
Journal: The Journal of Immunology
J Immunol (2018) 201 (11): 3199–3210.
https://doi.org/10.4049/jimmunol.1701487
Published: 01 December 2018
View article titled, FcγRIIb on B Cells and Myeloid Cells Modulates B Cell Activation and Autoantibody Responses via Different but Synergistic Pathways in Lupus-Prone <em>Yaa</em> Mice
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Includes: Supplementary data
Journal Articles

A Restricted Role for FcγR in the Regulation of Adaptive Immunity

Marieke F. Fransen, Hreinn Benonisson, Wendy W. van Maren, Heng Sheng Sow, Cor Breukel, Margot M. Linssen, Jill W. C. Claassens, Conny Brouwers, Jos van der Kaa, Marcel Camps, Jan Willem Kleinovink, Kelly K. Vonk, Sandra van Heiningen, Ngaisah Klar, Lianne van Beek, Vanessa van Harmelen, Lucia Daxinger, Kutty S. Nandakumar, Rikard Holmdahl, Chris Coward, Qingshun Lin, Sachiko Hirose, Daniela Salvatori, Thorbald van Hall, Cees van Kooten, Piero Mastroeni, Ferry Ossendorp, J. Sjef Verbeek
Journal: The Journal of Immunology
J Immunol (2018) 200 (8): 2615–2626.
https://doi.org/10.4049/jimmunol.1700429
Published: 15 April 2018
View article titled, A Restricted Role for FcγR in the Regulation of Adaptive Immunity
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Includes: Supplementary data
Journal Articles

Cd72c Is a Modifier Gene that Regulates Faslpr-Induced Autoimmune Disease

Miduo Xu, Rong Hou, Aya Sato-Hayashizaki, Rongyong Man, Chenghua Zhu, Chisato Wakabayashi, Sachiko Hirose, Takahiro Adachi, Takeshi Tsubata
Journal: The Journal of Immunology
J Immunol (2013) 190 (11): 5436–5445.
https://doi.org/10.4049/jimmunol.1203576
Published: 01 June 2013
View article titled, <em>Cd72<sup>c</sup></em> Is a Modifier Gene that Regulates <em>Fas<sup>lpr</sup></em>-Induced Autoimmune Disease
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Includes: Supplementary data
Journal Articles

Transgenic Overexpression of G5PR That Is Normally Augmented in Centrocytes Impairs the Enrichment of High-Affinity Antigen-Specific B Cells, Increases Peritoneal B-1a Cells, and Induces Autoimmunity in Aged Female Mice

Masahiro Kitabatake, Teppei Toda, Kazuhiko Kuwahara, Hideya Igarashi, Mareki Ohtsuji, Hiromichi Tsurui, Sachiko Hirose, Nobuo Sakaguchi
Journal: The Journal of Immunology
J Immunol (2012) 189 (3): 1193–1201.
https://doi.org/10.4049/jimmunol.1102774
Published: 01 August 2012
View article titled, Transgenic Overexpression of G5PR That Is Normally Augmented in Centrocytes Impairs the Enrichment of High-Affinity Antigen-Specific B Cells, Increases Peritoneal B-1a Cells, and Induces Autoimmunity in Aged Female Mice
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Includes: Supplementary data
Journal Articles

Genetic dissection of the effect of Fcgr2b polymorphism on systemic lupus erythematosus (49.30)

Sachiko Hirose, Qingshun Lin, Mareki Ohtsuji, Hiromichi Tsurui, Hiroyuki Nishimura, Toshikazu Shirai
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 49.30.
https://doi.org/10.4049/jimmunol.182.Supp.49.30
Published: 01 April 2009
View article titled, Genetic dissection of the effect of <em>Fcgr2b</em> polymorphism on systemic lupus erythematosus (49.30)
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Journal Articles

Splenic Phagocytes Promote Responses to Nucleosomes in (NZB × NZW) F1 Mice

Akiko Okamoto, Keishi Fujio, Nico van Rooijen, Nelson H. Tsuno, Koki Takahashi, Hiromichi Tsurui, Sachiko Hirose, Keith B. Elkon, Kazuhiko Yamamoto
Journal: The Journal of Immunology
J Immunol (2008) 181 (8): 5264–5271.
https://doi.org/10.4049/jimmunol.181.8.5264
Published: 15 October 2008
View article titled, Splenic Phagocytes Promote Responses to Nucleosomes in (NZB × NZW) F<sub>1</sub> Mice
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Journal Articles

Dissection of Genetic Mechanisms Governing the Expression of Serum Retroviral gp70 Implicated in Murine Lupus Nephritis

Lucie Baudino, Kumiko Yoshinobu, Naoki Morito, Shuichi Kikuchi, Liliane Fossati-Jimack, Bernard J. Morley, Timothy J. Vyse, Sachiko Hirose, Trine N. Jørgensen, Rebecca M. Tucker, Christina L. Roark, Brian L. Kotzin, Leonard H. Evans, Shozo Izui
Journal: The Journal of Immunology
J Immunol (2008) 181 (4): 2846–2854.
https://doi.org/10.4049/jimmunol.181.4.2846
Published: 15 August 2008
View article titled, Dissection of Genetic Mechanisms Governing the Expression of Serum Retroviral gp70 Implicated in Murine Lupus Nephritis
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Journal Articles

Aberrant Genetic Control of Invariant TCR-Bearing NKT Cell Function in New Zealand Mouse Strains: Possible Involvement in Systemic Lupus Erythematosus Pathogenesis

Kazuyuki Tsukamoto, Mareki Ohtsuji, Wakana Shiroiwa, Qingshun Lin, Kazuhiro Nakamura, Hiromichi Tsurui, Yi Jiang, Katsuko Sudo, Hiroyuki Nishimura, Toshikazu Shirai, Sachiko Hirose
Journal: The Journal of Immunology
J Immunol (2008) 180 (7): 4530–4539.
https://doi.org/10.4049/jimmunol.180.7.4530
Published: 01 April 2008
View article titled, Aberrant Genetic Control of Invariant TCR-Bearing NKT Cell Function in New Zealand Mouse Strains: Possible Involvement in Systemic Lupus Erythematosus Pathogenesis
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Journal Articles

Genetic Dissection of the Effects of Stimulatory and Inhibitory IgG Fc Receptors on Murine Lupus

Qingshun Lin, Yan Xiu, Yi Jiang, Hiromichi Tsurui, Kazuhiro Nakamura, Sanki Kodera, Mareki Ohtsuji, Naomi Ohtsuji, Wakana Shiroiwa, Kazuyuki Tsukamoto, Hirofumi Amano, Eri Amano, Katsuyuki Kinoshita, Katsuko Sudo, Hiroyuki Nishimura, Shozo Izui, Toshikazu Shirai, Sachiko Hirose
Journal: The Journal of Immunology
J Immunol (2006) 177 (3): 1646–1654.
https://doi.org/10.4049/jimmunol.177.3.1646
Published: 01 August 2006
View article titled, Genetic Dissection of the Effects of Stimulatory and Inhibitory IgG Fc Receptors on Murine Lupus
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Journal Articles

Genetic Dissection of Vasculitis, Myeloperoxidase-Specific Antineutrophil Cytoplasmic Autoantibody Production, and Related Traits in Spontaneous Crescentic Glomerulonephritis-Forming/Kinjoh Mice

Yoshitomo Hamano, Kazuyuki Tsukamoto, Masaaki Abe, Guo Dong Sun, Danqing Zhang, Hiroaki Fujii, Shuji Matsuoka, Masumi Tanaka, Akiko Ishida-Okawara, Hitoshi Tachikawa, Hiroyuki Nishimura, Kazuhiro Tokunaka, Sachiko Hirose, Kazuo Suzuki
Journal: The Journal of Immunology
J Immunol (2006) 176 (6): 3662–3673.
https://doi.org/10.4049/jimmunol.176.6.3662
Published: 15 March 2006
View article titled, Genetic Dissection of Vasculitis, Myeloperoxidase-Specific Antineutrophil Cytoplasmic Autoantibody Production, and Related Traits in Spontaneous Crescentic Glomerulonephritis-Forming/Kinjoh Mice
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Journal Articles

Nucleosome-Specific Regulatory T Cells Engineered by Triple Gene Transfer Suppress a Systemic Autoimmune Disease

Keishi Fujio, Akiko Okamoto, Hiroyuki Tahara, Masaaki Abe, Yi Jiang, Toshio Kitamura, Sachiko Hirose, Kazuhiko Yamamoto
Journal: The Journal of Immunology
J Immunol (2004) 173 (3): 2118–2125.
https://doi.org/10.4049/jimmunol.173.3.2118
Published: 01 August 2004
View article titled, Nucleosome-Specific Regulatory T Cells Engineered by Triple Gene Transfer Suppress a Systemic Autoimmune Disease
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Journal Articles

Involvement of Inducible Costimulator-B7 Homologous Protein Costimulatory Pathway in Murine Lupus Nephritis

Hideyuki Iwai, Masaaki Abe, Sachiko Hirose, Fumihiko Tsushima, Katsunari Tezuka, Hisaya Akiba, Hideo Yagita, Ko Okumura, Hitoshi Kohsaka, Nobuyuki Miyasaka, Miyuki Azuma
Journal: The Journal of Immunology
J Immunol (2003) 171 (6): 2848–2854.
https://doi.org/10.4049/jimmunol.171.6.2848
Published: 15 September 2003
View article titled, Involvement of Inducible Costimulator-B7 Homologous Protein Costimulatory Pathway in Murine Lupus Nephritis
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Journal Articles

Amelioration of Collagen-Induced Arthritis by Blockade of Inducible Costimulator-B7 Homologous Protein Costimulation

Hideyuki Iwai, Yuko Kozono, Sachiko Hirose, Hisaya Akiba, Hideo Yagita, Ko Okumura, Hitoshi Kohsaka, Nobuyuki Miyasaka, Miyuki Azuma
Journal: The Journal of Immunology
J Immunol (2002) 169 (8): 4332–4339.
https://doi.org/10.4049/jimmunol.169.8.4332
Published: 15 October 2002
View article titled, Amelioration of Collagen-Induced Arthritis by Blockade of Inducible Costimulator-B7 Homologous Protein Costimulation
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Journal Articles

Transcriptional Regulation of Fcgr2b Gene by Polymorphic Promoter Region and Its Contribution to Humoral Immune Responses

Yan Xiu, Kazuhiro Nakamura, Masaaki Abe, Na Li, Xiang Shu Wen, Yi Jiang, Danqing Zhang, Hiromichi Tsurui, Shuji Matsuoka, Yoshitomo Hamano, Hiroyuki Fujii, Masao Ono, Toshiyuki Takai, Toshibumi Shimokawa, Chisei Ra, Toshikazu Shirai, Sachiko Hirose
Journal: The Journal of Immunology
J Immunol (2002) 169 (8): 4340–4346.
https://doi.org/10.4049/jimmunol.169.8.4340
Published: 15 October 2002
View article titled, Transcriptional Regulation of <em>Fcgr2b</em> Gene by Polymorphic Promoter Region and Its Contribution to Humoral Immune Responses
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Journal Articles

C1q Regulatory Region Polymorphism Down-Regulating Murine C1q Protein Levels with Linkage to Lupus Nephritis

Yuko Miura-Shimura, Kazuhiro Nakamura, Mareki Ohtsuji, Hideaki Tomita, Yi Jiang, Masaaki Abe, Danqing Zhang, Yoshitomo Hamano, Hiroshi Tsuda, Hiroshi Hashimoto, Hiroyuki Nishimura, Shinsuke Taki, Toshikazu Shirai, Sachiko Hirose
Journal: The Journal of Immunology
J Immunol (2002) 169 (3): 1334–1339.
https://doi.org/10.4049/jimmunol.169.3.1334
Published: 01 August 2002
View article titled, C1q Regulatory Region Polymorphism Down-Regulating Murine C1q Protein Levels with Linkage to Lupus Nephritis
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Reactivity of Anti-Proliferating Cell Nuclear Antigen (PCNA) Murine Monoclonal Antibodies and Human Autoantibodies to the PCNA Multiprotein Complexes Involved in Cell Proliferation

Yoshinari Takasaki, Toshiaki Kogure, Ken Takeuchi, Kazuhiko Kaneda, Tetsuro Yano, Kaoru Hirokawa, Sachiko Hirose, Toshikazu Shirai, Hiroshi Hashimoto
Journal: The Journal of Immunology
J Immunol (2001) 166 (7): 4780–4787.
https://doi.org/10.4049/jimmunol.166.7.4780
Published: 01 April 2001
View article titled, Reactivity of Anti-Proliferating Cell Nuclear Antigen (PCNA) Murine Monoclonal Antibodies and Human Autoantibodies to the PCNA Multiprotein Complexes Involved in Cell Proliferation
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Journal Articles

L-Selectin-Specific Autoantibodies in Murine Lupus: Possible Involvement in Abnormal Homing and Polarization of CD4+ T Cell Subsets

Susumu Hattori, Hiroyuki Nishimura, Hiromichi Tsurui, Masayuki Kato, Naoki Endo, Masaaki Abe, Shin Akakura, Kenichi Mitsui, Sho Ishikawa, Sachiko Hirose, Toshikazu Shirai
Journal: The Journal of Immunology
J Immunol (1998) 161 (3): 1231–1238.
https://doi.org/10.4049/jimmunol.161.3.1231
Published: 01 August 1998
View article titled, L-Selectin-Specific Autoantibodies in Murine Lupus: Possible Involvement in Abnormal Homing and Polarization of CD4<sup>+</sup> T Cell Subsets
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A Subset of CD4+ T Cells Expressing Early Activation Antigen CD69 in Murine Lupus: Possible Abnormal Regulatory Role for Cytokine Imbalance

Sho Ishikawa, Shin Akakura, Masaaki Abe, Kazuo Terashima, Karina Chijiiwa, Hiroyuki Nishimura, Sachiko Hirose, Toshikazu Shirai
Journal: The Journal of Immunology
J Immunol (1998) 161 (3): 1267–1273.
https://doi.org/10.4049/jimmunol.161.3.1267
Published: 01 August 1998
View article titled, A Subset of CD4<sup>+</sup> T Cells Expressing Early Activation Antigen CD69 in Murine Lupus: Possible Abnormal Regulatory Role for Cytokine Imbalance
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Monoclonal Anti-Cardiolipin Antibodies from New Zealand Black × New Zealand White F1 Mice React to Thrombomodulin

Kazuhiko Haruta, Shigeto Kobayashi, Sachiko Hirose, Aiko Horiai, Mutsuko Ohyanagi, Mitsuhiko Tanaka, Terunaga Kawano, Toshikazu Shirai, Yoshinari Takasaki, Hiroshi Hashimoto
Journal: The Journal of Immunology
J Immunol (1998) 160 (1): 253–258.
https://doi.org/10.4049/jimmunol.160.1.253
Published: 01 January 1998
View article titled, Monoclonal Anti-Cardiolipin Antibodies from New Zealand Black × New Zealand White F<sub>1</sub> Mice React to Thrombomodulin
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