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Seppo Meri
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Journal Articles

The Salivary Scavenger and Agglutinin in Early Life: Diverse Roles in Amniotic Fluid and in the Infant Intestine

Martin Parnov Reichhardt, Hanna Jarva, Mark de Been, Juan Miguel Rodriguez, Esther Jimenez Quintana, Vuokko Loimaranta, Willem Meindert de Vos, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2014) 193 (10): 5240–5248.
https://doi.org/10.4049/jimmunol.1401631
Published: 15 November 2014
View article titled, The Salivary Scavenger and Agglutinin in Early Life: Diverse Roles in Amniotic Fluid and in the Infant Intestine
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Journal Articles

The Yersinia pseudotuberculosis Outer Membrane Protein Ail Recruits the Human Complement Regulatory Protein Factor H

Derek K. Ho, Rauna Riva, Mikael Skurnik, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2012) 189 (7): 3593–3599.
https://doi.org/10.4049/jimmunol.1201145
Published: 01 October 2012
View article titled, The <em>Yersinia pseudotuberculosis</em> Outer Membrane Protein Ail Recruits the Human Complement Regulatory Protein Factor H
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Journal Articles

Functional Recruitment of the Human Complement Inhibitor C4BP to Yersinia pseudotuberculosis Outer Membrane Protein Ail

Derek K. Ho, Rauna Riva, Vesa Kirjavainen, Hanna Jarva, Erica Ginström, Anna M. Blom, Mikael Skurnik, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2012) 188 (9): 4450–4459.
https://doi.org/10.4049/jimmunol.1103149
Published: 01 May 2012
View article titled, Functional Recruitment of the Human Complement Inhibitor C4BP to <em>Yersinia pseudotuberculosis</em> Outer Membrane Protein Ail
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Journal Articles

Acquisition of Complement Factor H Is Important for Pathogenesis of Streptococcus pyogenes Infections: Evidence from Bacterial In Vitro Survival and Human Genetic Association

Karita Haapasalo, Jaana Vuopio, Jaana Syrjänen, Jari Suvilehto, Satu Massinen, Matti Karppelin, Irma Järvelä, Seppo Meri, Juha Kere, T. Sakari Jokiranta
Journal: The Journal of Immunology
J Immunol (2012) 188 (1): 426–435.
https://doi.org/10.4049/jimmunol.1102545
Published: 01 January 2012
View article titled, Acquisition of Complement Factor H Is Important for Pathogenesis of <em>Streptococcus pyogenes</em> Infections: Evidence from Bacterial In Vitro Survival and Human Genetic Association
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Includes: Supplementary data
Journal Articles

Human Complement Factor H Binds to Outer Membrane Protein Rck of Salmonella

Derek K. Ho, Hanna Jarva, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2010) 185 (3): 1763–1769.
https://doi.org/10.4049/jimmunol.1001244
Published: 01 August 2010
View article titled, Human Complement Factor H Binds to Outer Membrane Protein Rck of <em>Salmonella</em>
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Journal Articles

Clinical Isolates of Streptococcus pneumoniae Bind the Complement Inhibitor C4b-Binding Protein in a PspC Allele-Dependent Fashion

Antoine Dieudonné-Vatran, Stefanie Krentz, Anna M. Blom, Seppo Meri, Birgitta Henriques-Normark, Kristian Riesbeck, Barbara Albiger
Journal: The Journal of Immunology
J Immunol (2009) 182 (12): 7865–7877.
https://doi.org/10.4049/jimmunol.0802376
Published: 15 June 2009
View article titled, Clinical Isolates of <em>Streptococcus pneumoniae</em> Bind the Complement Inhibitor C4b-Binding Protein in a PspC Allele-Dependent Fashion
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Journal Articles

Factor H Binding as a Complement Evasion Mechanism for an Anaerobic Pathogen, Fusobacterium necrophorum

Nathalie Friberg, Petteri Carlson, Erna Kentala, Petri S. Mattila, Pentti Kuusela, Seppo Meri, Hanna Jarva
Journal: The Journal of Immunology
J Immunol (2008) 181 (12): 8624–8632.
https://doi.org/10.4049/jimmunol.181.12.8624
Published: 15 December 2008
View article titled, Factor H Binding as a Complement Evasion Mechanism for an Anaerobic Pathogen, <em>Fusobacterium necrophorum</em>
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Journal Articles

Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation

Livija Deban, Hanna Jarva, Markus J. Lehtinen, Barbara Bottazzi, Antonio Bastone, Andrea Doni, T. Sakari Jokiranta, Alberto Mantovani, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2008) 181 (12): 8433–8440.
https://doi.org/10.4049/jimmunol.181.12.8433
Published: 15 December 2008
View article titled, Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation
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Journal Articles

Y402H Polymorphism of Complement Factor H Affects Binding Affinity to C-Reactive Protein

Matti Laine, Hanna Jarva, Sanna Seitsonen, Karita Haapasalo, Markus J. Lehtinen, Nina Lindeman, Don H. Anderson, Patrick T. Johnson, Irma Järvelä, T. Sakari Jokiranta, Gregory S. Hageman, Ilkka Immonen, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2007) 178 (6): 3831–3836.
https://doi.org/10.4049/jimmunol.178.6.3831
Published: 15 March 2007
View article titled, Y402H Polymorphism of Complement Factor H Affects Binding Affinity to C-Reactive Protein
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Journal Articles

Complement Regulator-Acquiring Surface Protein 1 Imparts Resistance to Human Serum in Borrelia burgdorferi

Chad S. Brooks, Santosh R. Vuppala, Amy M. Jett, Antti Alitalo, Seppo Meri, Darrin R. Akins
Journal: The Journal of Immunology
J Immunol (2005) 175 (5): 3299–3308.
https://doi.org/10.4049/jimmunol.175.5.3299
Published: 01 September 2005
View article titled, Complement Regulator-Acquiring Surface Protein 1 Imparts Resistance to Human Serum in <em>Borrelia burgdorferi</em>
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Journal Articles

Binding of the Complement Inhibitor C4bp to Serogroup B Neisseria meningitidis

Hanna Jarva, Sanjay Ram, Ulrich Vogel, Anna M. Blom, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2005) 174 (10): 6299–6307.
https://doi.org/10.4049/jimmunol.174.10.6299
Published: 15 May 2005
View article titled, Binding of the Complement Inhibitor C4bp to Serogroup B <em>Neisseria meningitidis</em>
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Journal Articles

IFN-α Enhances TLR3-Mediated Antiviral Cytokine Expression in Human Endothelial and Epithelial Cells by Up-Regulating TLR3 Expression

Jorma Tissari, Jukka Sirén, Seppo Meri, Ilkka Julkunen, Sampsa Matikainen
Journal: The Journal of Immunology
J Immunol (2005) 174 (7): 4289–4294.
https://doi.org/10.4049/jimmunol.174.7.4289
Published: 01 April 2005
View article titled, IFN-α Enhances TLR3-Mediated Antiviral Cytokine Expression in Human Endothelial and Epithelial Cells by Up-Regulating TLR3 Expression
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Journal Articles

Lysine-Dependent Multipoint Binding of the Borrelia burgdorferi Virulence Factor Outer Surface Protein E to the C Terminus of Factor H

Antti Alitalo, Taru Meri, Tong Chen, Hilkka Lankinen, Zhu-Zhu Cheng, T. Sakari Jokiranta, Ilkka J. T. Seppälä, Pekka Lahdenne, P. Scott Hefty, Darrin R. Akins, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2004) 172 (10): 6195–6201.
https://doi.org/10.4049/jimmunol.172.10.6195
Published: 15 May 2004
View article titled, Lysine-Dependent Multipoint Binding of the <em>Borrelia burgdorferi</em> Virulence Factor Outer Surface Protein E to the C Terminus of Factor H
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Journal Articles

The Group B Streptococcal β and Pneumococcal Hic Proteins Are Structurally Related Immune Evasion Molecules That Bind the Complement Inhibitor Factor H in an Analogous Fashion

Hanna Jarva, Jens Hellwage, T. Sakari Jokiranta, Markus J. Lehtinen, Peter F. Zipfel, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2004) 172 (5): 3111–3118.
https://doi.org/10.4049/jimmunol.172.5.3111
Published: 01 March 2004
View article titled, The Group B Streptococcal β and Pneumococcal Hic Proteins Are Structurally Related Immune Evasion Molecules That Bind the Complement Inhibitor Factor H in an Analogous Fashion
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Journal Articles

Complement C3b/C3d and Cell Surface Polyanions Are Recognized by Overlapping Binding Sites on the Most Carboxyl-Terminal Domain of Complement Factor H

Jens Hellwage, T. Sakari Jokiranta, Manuel A. Friese, Tobias U. Wolk, Eva Kampen, Peter F. Zipfel, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2002) 169 (12): 6935–6944.
https://doi.org/10.4049/jimmunol.169.12.6935
Published: 15 December 2002
View article titled, Complement C3b/C3d and Cell Surface Polyanions Are Recognized by Overlapping Binding Sites on the Most Carboxyl-Terminal Domain of Complement Factor H
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Journal Articles

Complement Inhibitor Factor H Binding to Lyme Disease Spirochetes Is Mediated by Inducible Expression of Multiple Plasmid-Encoded Outer Surface Protein E Paralogs

Antti Alitalo, Taru Meri, Hilkka Lankinen, Ilkka Seppälä, Pekka Lahdenne, P. Scott Hefty, Darrin Akins, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2002) 169 (7): 3847–3853.
https://doi.org/10.4049/jimmunol.169.7.3847
Published: 01 October 2002
View article titled, Complement Inhibitor Factor H Binding to Lyme Disease Spirochetes Is Mediated by Inducible Expression of Multiple Plasmid-Encoded Outer Surface Protein E Paralogs
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Journal Articles

Streptococcus pneumoniae Evades Complement Attack and Opsonophagocytosis by Expressing the pspC Locus-Encoded Hic Protein That Binds to Short Consensus Repeats 8–11 of Factor H

Hanna Jarva, Robert Janulczyk, Jens Hellwage, Peter F. Zipfel, Lars Björck, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2002) 168 (4): 1886–1894.
https://doi.org/10.4049/jimmunol.168.4.1886
Published: 15 February 2002
View article titled, <em>Streptococcus pneumoniae</em> Evades Complement Attack and Opsonophagocytosis by Expressing the <em>pspC</em> Locus-Encoded Hic Protein That Binds to Short Consensus Repeats 8–11 of Factor H
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Journal Articles

Regulation of Complement Classical Pathway by Association of C4b-Binding Protein to the Surfaces of SK-OV-3 and Caov-3 Ovarian Adenocarcinoma Cells

Mikko T. Holmberg, Anna M. Blom, Seppo Meri
Journal: The Journal of Immunology
J Immunol (2001) 167 (2): 935–939.
https://doi.org/10.4049/jimmunol.167.2.935
Published: 15 July 2001
View article titled, Regulation of Complement Classical Pathway by Association of C4b-Binding Protein to the Surfaces of SK-OV-3 and Caov-3 Ovarian Adenocarcinoma Cells
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Journal Articles

Molecular Mechanisms of Target Recognition in an Innate Immune System: Interactions Among Factor H, C3b, and Target in the Alternative Pathway of Human Complement

Michael K. Pangburn, Kerry L. W. Pangburn, Vesa Koistinen, Seppo Meri, Ajay K. Sharma
Journal: The Journal of Immunology
J Immunol (2000) 164 (9): 4742–4751.
https://doi.org/10.4049/jimmunol.164.9.4742
Published: 01 May 2000
View article titled, Molecular Mechanisms of Target Recognition in an Innate Immune System: Interactions Among Factor H, C3b, and Target in the Alternative Pathway of Human Complement
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Journal Articles

Nephritogenic λ Light Chain Dimer: A Unique Human Miniautoantibody Against Complement Factor H

T. Sakari Jokiranta, Alan Solomon, Michael K. Pangburn, Peter F. Zipfel, Seppo Meri
Journal: The Journal of Immunology
J Immunol (1999) 163 (8): 4590–4596.
https://doi.org/10.4049/jimmunol.163.8.4590
Published: 15 October 1999
View article titled, Nephritogenic λ Light Chain Dimer: A Unique Human Miniautoantibody Against Complement Factor H
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