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Sian Llewellyn-Lacey
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Journal Articles

Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8+ T Cells in Elderly Humans

Francesco Nicoli, Mariela P. Cabral-Piccin, Laura Papagno, Eleonora Gallerani, Mathieu Fusaro, Victor Folcher, Marion Dubois, Emmanuel Clave, Hélène Vallet, Justin J. Frere, Emma Gostick, Sian Llewellyn-Lacey, David A. Price, Antoine Toubert, Loïc Dupré, Jacques Boddaert, Antonella Caputo, Riccardo Gavioli, Victor Appay
Journal: The Journal of Immunology
J Immunol (2022) 208 (3): 562–570.
https://doi.org/10.4049/jimmunol.2100194
Published: 01 February 2022
View article titled, Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8<sup>+</sup> T Cells in Elderly Humans
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Includes: Supplementary data
Journal Articles

Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells

Stephen Man, James E. Redman, Deborah L. Cross, David K. Cole, Ilona Can, Bethan Davies, Shaikh Shimaz Hashimdeen, Reiss Reid, Sian Llewellyn-Lacey, Kelly L. Miners, Kristin Ladell, Anya Lissina, Paul E. Brown, Linda Wooldridge, David A. Price, Pierre J. Rizkallah
Journal: The Journal of Immunology
J Immunol (2021) 207 (4): 1009–1017.
https://doi.org/10.4049/jimmunol.2000756
Published: 15 August 2021
View article titled, Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells
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Includes: Supplementary data
Journal Articles

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine

James E. McLaren, Mathew Clement, Morgan Marsden, Kelly L. Miners, Sian Llewellyn-Lacey, Emma J. Grant, Anzelika Rubina, Silvia Gimeno Brias, Emma Gostick, Maria A. Stacey, Selinda J. Orr, Richard J. Stanton, Kristin Ladell, David A. Price, Ian R. Humphreys
Journal: The Journal of Immunology
J Immunol (2019) 202 (3): 943–955.
https://doi.org/10.4049/jimmunol.1701757
Published: 01 February 2019
View article titled, IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine
Open the PDF for IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine in another window
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Includes: Supplementary data
Journal Articles

Autoreactive CD8+ T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8+ T-cell activation

Linda Wooldridge, David Morgan, James Alexander Pearson, Stephanie Gras, Hugo van den Berg, Anya Lissina, Sian Llewellyn-Lacey, Mark Willis, Tamsin Dockree, James E McLaren, Julia Ekeruche-Makinde, Emma Gostick, Neil Robertson, Jamie Rossjohn, Scott R Burrows, David Price, Susan Wong, Mark Peakman, Ania Skowera, Matthew Clement
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 127.26.
https://doi.org/10.4049/jimmunol.198.Supp.127.26
Published: 01 May 2017
View article titled, Autoreactive CD8<sup>+</sup> T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8<sup>+</sup> T-cell activation
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