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Silva Markovic-Plese
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Journal Articles

Microparticle-delivered stimulator of interferon genes (STING) agonist suppresses experimental autoimmune encephalomyelitis (EAE) via expansion of FoxP3 +CD4 +Tregs

Free
Manal Ali Elzoheiry, Yan Wang, Ezgi Kasimoglu, Maryamsadat Seyedsadr, Cole Batty, Eric Bachelder, Ainslie Kristy, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 238.03.
https://doi.org/10.4049/jimmunol.210.Supp.238.03
Published: 01 May 2023
View articletitled, Microparticle-delivered stimulator of interferon genes (STING) agonist suppresses experimental autoimmune encephalomyelitis (EAE) via expansion of FoxP3 +CD4 +Tregs
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Journal Articles

Therapeutic Effect of Anti-CD52 Monoclonal Antibody in Multiple Sclerosis and Its Animal Models Is Mediated via T Regulatory Cells

Open Access
Nazanin Kiapour, Bing Wu, Yan Wang, Maryamsadat Seyedsadr, Sahil Kapoor, Xin Zhang, Manal Elzoheiry, Ezgi Kasimoglu, Yisong Wan, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2022) 209 (1): 49–56.
https://doi.org/10.4049/jimmunol.2100176
Published: 01 July 2022
View articletitled, Therapeutic Effect of Anti-CD52 Monoclonal Antibody in Multiple Sclerosis and Its Animal Models Is Mediated via T Regulatory Cells
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Includes: Supplementary data
Journal Articles

Single-cell RNA sequence (scRNAseq) analysis of T regulatory cells in relapsing remitting multiple sclerosis (RRMS)

Free
Yan Wang, Maryamsadat Seyedsadr, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 162.13.
https://doi.org/10.4049/jimmunol.208.Supp.162.13
Published: 01 May 2022
View articletitled, Single-cell RNA sequence (scRNAseq) analysis of T regulatory cells in relapsing remitting multiple sclerosis (RRMS)
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Journal Articles

IL-11 induces monocyte inflammasome activation and migration to the CNS in IL-11R+ cells in relapsing remitting multiple sclerosis (RRMS)

Free
Maryamsadat Seyedsadr, Yan Wang, Manal Alzoheiry, Ezgi kasimoglu, Daniel Hwang, James Garifallou, Dhanashri Miskin, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 46.06.
https://doi.org/10.4049/jimmunol.208.Supp.46.06
Published: 01 May 2022
View articletitled, IL-11 induces monocyte inflammasome activation and migration to the CNS in IL-11R+ cells in relapsing remitting multiple sclerosis (RRMS)
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Journal Articles

STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN–Dependent and –Independent Immune-Regulatory Pathways

Free
Brandon M. Johnson, Toru Uchimura, Matthew D. Gallovic, Madhan Thamilarasan, Wei-Chun Chou, Sara A. Gibson, Meng Deng, Jason W. Tam, Cole J. Batty, Jonathan Williams, Glenn K. Matsushima, Eric M. Bachelder, Kristy M. Ainslie, Silva Markovic-Plese, Jenny P.-Y. Ting
Journal: The Journal of Immunology
J Immunol (2021) 206 (9): 2015–2028.
https://doi.org/10.4049/jimmunol.2001317
Published: 01 May 2021
View articletitled, STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN–Dependent and –Independent Immune-Regulatory Pathways
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Includes: Supplementary data
Journal Articles

IL-11 induces surface marker expression and migration of T-lymphocytes

Free
Maryamsadat Seyedsadr, Jian Li, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 220.29.
https://doi.org/10.4049/jimmunol.204.Supp.220.29
Published: 01 May 2020
View articletitled, IL-11 induces surface marker expression and migration of T-lymphocytes
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Journal Articles

IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

Open Access
Xin Zhang, Nazanin Kiapour, Sahil Kapoor, Tabish Khan, Madhan Thamilarasan, Yazhong Tao, Stephanie Cohen, Ryan Miller, Raymond A. Sobel, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2019) 203 (5): 1142–1150.
https://doi.org/10.4049/jimmunol.1900311
Published: 01 September 2019
View articletitled, IL-11 Induces Encephalitogenic Th17 Cells in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
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Includes: Supplementary data
Journal Articles

Regulation of Immunomodulatory Cytokine Secretion by IFNb-1a is Mediated through Up-regulation of IRF7-SOCS1 Signaling in Monocytes from Patients with Relapsing-Remitting Multiple Sclerosis

Free
Xin Zhang, Yazhong Tao, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 210.2.
https://doi.org/10.4049/jimmunol.198.Supp.210.2
Published: 01 May 2017
View articletitled, Regulation of Immunomodulatory Cytokine Secretion by IFNb-1a is Mediated through Up-regulation of IRF7-SOCS1 Signaling in Monocytes from Patients with Relapsing-Remitting Multiple Sclerosis
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Journal Articles

IL-11 induces encephalitogenic Th17 cells

Free
Nazanin Kiapour, Xin Zhang, Tabish Hasan Khan, Madhan Thamilarasan, Sahil Kapoor, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 210.11.
https://doi.org/10.4049/jimmunol.198.Supp.210.11
Published: 01 May 2017
View articletitled, IL-11 induces encephalitogenic Th17 cells
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Journal Articles

IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis

Free
Xin Zhang, Yazhong Tao, Manisha Chopra, Irena Dujmovic-Basuroski, Jianping Jin, Yunan Tang, Jelena Drulovic, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2015) 194 (11): 5139–5149.
https://doi.org/10.4049/jimmunol.1401680
Published: 01 June 2015
View articletitled, IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis
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Includes: Supplementary data
Journal Articles

The Role of Endogenous IFN-β in the Regulation of Th17 Responses in Patients with Relapsing-Remitting Multiple Sclerosis

Free
Yazhong Tao, Xin Zhang, Manisha Chopra, Ming-Jeong Kim, Kinnari R. Buch, Dehan Kong, Jianping Jin, Yunan Tang, Hongtu Zhu, Valerie Jewells, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2014) 192 (12): 5610–5617.
https://doi.org/10.4049/jimmunol.1302580
Published: 15 June 2014
View articletitled, The Role of Endogenous IFN-β in the Regulation of Th17 Responses in Patients with Relapsing-Remitting Multiple Sclerosis
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Includes: Supplementary data
Journal Articles

Differential Reconstitution of T Cell Subsets following Immunodepleting Treatment with Alemtuzumab (Anti-CD52 Monoclonal Antibody) in Patients with Relapsing–Remitting Multiple Sclerosis

Free
Xin Zhang, Yazhong Tao, Manisha Chopra, Mihye Ahn, Karen L. Marcus, Neelima Choudhary, Hongtu Zhu, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2013) 191 (12): 5867–5874.
https://doi.org/10.4049/jimmunol.1301926
Published: 15 December 2013
View articletitled, Differential Reconstitution of T Cell Subsets following Immunodepleting Treatment with Alemtuzumab (Anti-CD52 Monoclonal Antibody) in Patients with Relapsing–Remitting Multiple Sclerosis
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Includes: Supplementary data
Journal Articles

Prognostic immunological markers in patients with relapsing-remitting multiple sclerosis: a prospective magnetization transfer brain imaging study (P3117)

Free
Silva Markovic-Plese, Yazhong Tao, Xin Zhang, Bianca Weinstock-Guttman, Brooke Hayward, Fernando Dangond, Robert Zivadinov
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 43.20.
https://doi.org/10.4049/jimmunol.190.Supp.43.20
Published: 01 May 2013
View articletitled, Prognostic immunological markers in patients with relapsing-remitting multiple sclerosis: a prospective magnetization transfer brain imaging study (P3117)
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Journal Articles

Simvastatin Inhibits IFN Regulatory Factor 4 Expression and Th17 Cell Differentiation in CD4+ T Cells Derived from Patients with Multiple Sclerosis

Free
Xin Zhang, Yazhong Tao, Luigi Troiani, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2011) 187 (6): 3431–3437.
https://doi.org/10.4049/jimmunol.1100580
Published: 15 September 2011
View articletitled, Simvastatin Inhibits IFN Regulatory Factor 4 Expression and Th17 Cell Differentiation in CD4+ T Cells Derived from Patients with Multiple Sclerosis
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Includes: Supplementary data
Journal Articles

B-cells are a therapeutic target for IFNβ in relapsing-remitting multiple sclerosis (167.17)

Free
Karen Marcus, Vinod Ramgolam, Yonggang Sha, Neelima Choudhary, Luigi Troiani, Manisha Chopra, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 167.17.
https://doi.org/10.4049/jimmunol.186.Supp.167.17
Published: 01 April 2011
View articletitled, B-cells are a therapeutic target for IFNβ in relapsing-remitting multiple sclerosis (167.17)
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Journal Articles

B Cells as a Therapeutic Target for IFN-β in Relapsing–Remitting Multiple Sclerosis

Free
Vinod S. Ramgolam, Yonggang Sha, Karen L. Marcus, Neelima Choudhary, Luigi Troiani, Manisha Chopra, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2011) 186 (7): 4518–4526.
https://doi.org/10.4049/jimmunol.1000271
Published: 01 April 2011
View articletitled, B Cells as a Therapeutic Target for IFN-β in Relapsing–Remitting Multiple Sclerosis
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Includes: Supplementary data
Journal Articles

TLR7 and TLR9 9 agonists enhance the exogenous IFNb-1a’s induction of immunomodulatory cytokine secretion via reconstituting a deficient IFNAR/TLR7 signaling in patients with relapsing remitting multiple sclerosis (164.16)

Free
Yazhong Tao, Xin Zhang, Luigi Troiani, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 164.16.
https://doi.org/10.4049/jimmunol.186.Supp.164.16
Published: 01 April 2011
View articletitled, TLR7 and TLR9 9 agonists enhance the exogenous IFNb-1a’s induction of immunomodulatory cytokine secretion via reconstituting a deficient IFNAR/TLR7 signaling in patients with relapsing remitting multiple sclerosis (164.16)
Add to Citation Manager for TLR7 and TLR9 9 agonists enhance the exogenous IFNb-1a’s induction of immunomodulatory cytokine secretion via reconstituting a deficient IFNAR/TLR7 signaling in patients with relapsing remitting multiple sclerosis (164.16)
Journal Articles

Activated IL-1R1 Signaling Pathway Induces Th17 Cell Differentiation in Patients with Relapsing Remitting Multiple Sclerosis (83.18)

Free
Yonggang Sha, Luigi Troiani, Manisha Chopra, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 83.18.
https://doi.org/10.4049/jimmunol.184.Supp.83.18
Published: 01 April 2010
View articletitled, Activated IL-1R1 Signaling Pathway Induces Th17 Cell Differentiation in Patients with Relapsing Remitting Multiple Sclerosis (83.18)
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Journal Articles

IFN-β Inhibits Human Th17 Cell Differentiation

Free
Vinod S. Ramgolam, Yonggang Sha, Jianping Jin, Xin Zhang, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2009) 183 (8): 5418–5427.
https://doi.org/10.4049/jimmunol.0803227
Published: 15 October 2009
View articletitled, IFN-β Inhibits Human Th17 Cell Differentiation
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Journal Articles

IFN-β1a Inhibits the Secretion of Th17-Polarizing Cytokines in Human Dendritic Cells via TLR7 Up-Regulation

Free
Xin Zhang, Jianping Jin, Yunan Tang, Danielle Speer, Danuta Sujkowska, Silva Markovic-Plese
Journal: The Journal of Immunology
J Immunol (2009) 182 (6): 3928–3936.
https://doi.org/10.4049/jimmunol.0802226
Published: 15 March 2009
View articletitled, IFN-β1a Inhibits the Secretion of Th17-Polarizing Cytokines in Human Dendritic Cells via TLR7 Up-Regulation
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Includes: Supplementary data