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Journal Articles

Computational Modeling Predicts IL-10 Control of Lesion Sterilization by Balancing Early Host Immunity–Mediated Antimicrobial Responses with Caseation during Mycobacterium tuberculosis Infection

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Nicholas A. Cilfone, Christopher B. Ford, Simeone Marino, Joshua T. Mattila, Hannah P. Gideon, JoAnne L. Flynn, Denise E. Kirschner, Jennifer J. Linderman
Journal: The Journal of Immunology
J Immunol (2015) 194 (2): 664–677.
https://doi.org/10.4049/jimmunol.1400734
Published: 15 January 2015
View articletitled, Computational Modeling Predicts IL-10 Control of Lesion Sterilization by Balancing Early Host Immunity–Mediated Antimicrobial Responses with Caseation during Mycobacterium tuberculosis Infection
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Includes: Supplementary data
Journal Articles

Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection (IRC5P.475)

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Simeone Marino, Nicholas Cilfone, Joshua Mattila, JoAnne Flynn, Jennifer Linderman, Denise Kirschner
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 125.24.
https://doi.org/10.4049/jimmunol.192.Supp.125.24
Published: 01 May 2014
View articletitled, Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection (IRC5P.475)
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Journal Articles

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

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Joshua T. Mattila, Olabisi O. Ojo, Diane Kepka-Lenhart, Simeone Marino, Jin Hee Kim, Seok Yong Eum, Laura E. Via, Clifton E. Barry, III, Edwin Klein, Denise E. Kirschner, Sidney M. Morris, Jr., Philana Ling Lin, JoAnne L. Flynn
Journal: The Journal of Immunology
J Immunol (2013) 191 (2): 773–784.
https://doi.org/10.4049/jimmunol.1300113
Published: 15 July 2013
View articletitled, Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms
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Includes: Supplementary data
Journal Articles

Inoculation Dose of Mycobacterium tuberculosis Does Not Influence Priming of T Cell Responses in Lymph Nodes

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Amy J. Myers, Simeone Marino, Denise E. Kirschner, JoAnne L. Flynn
Journal: The Journal of Immunology
J Immunol (2013) 190 (9): 4707–4716.
https://doi.org/10.4049/jimmunol.1203465
Published: 01 May 2013
View articletitled, Inoculation Dose of Mycobacterium tuberculosis Does Not Influence Priming of T Cell Responses in Lymph Nodes
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Includes: Supplementary data
Journal Articles

Multiscale Computational Modeling Reveals a Critical Role for TNF-α Receptor 1 Dynamics in Tuberculosis Granuloma Formation

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Mohammad Fallahi-Sichani, Mohammed El-Kebir, Simeone Marino, Denise E. Kirschner, Jennifer J. Linderman
Journal: The Journal of Immunology
J Immunol (2011) 186 (6): 3472–3483.
https://doi.org/10.4049/jimmunol.1003299
Published: 15 March 2011
View articletitled, Multiscale Computational Modeling Reveals a Critical Role for TNF-α Receptor 1 Dynamics in Tuberculosis Granuloma Formation
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Journal Articles

Characterizing the Dynamics of CD4+ T Cell Priming within a Lymph Node

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Jennifer J. Linderman, Thomas Riggs, Manjusha Pande, Mark Miller, Simeone Marino, Denise E. Kirschner
Journal: The Journal of Immunology
J Immunol (2010) 184 (6): 2873–2885.
https://doi.org/10.4049/jimmunol.0903117
Published: 15 March 2010
View articletitled, Characterizing the Dynamics of CD4+ T Cell Priming within a Lymph Node
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Journal Articles

Dendritic Cell Trafficking and Antigen Presentation in the Human Immune Response to Mycobacterium tuberculosis

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Simeone Marino, Santosh Pawar, Craig L. Fuller, Todd A. Reinhart, JoAnne L. Flynn, Denise E. Kirschner
Journal: The Journal of Immunology
J Immunol (2004) 173 (1): 494–506.
https://doi.org/10.4049/jimmunol.173.1.494
Published: 01 July 2004
View articletitled, Dendritic Cell Trafficking and Antigen Presentation in the Human Immune Response to Mycobacterium tuberculosis
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