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Simon Rothenfusser
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Journal Articles

Cytosolic DNA Triggers Mitochondrial Apoptosis via DNA Damage Signaling Proteins Independently of AIM2 and RNA Polymerase III

Michael Wenzel, Michael Wunderlich, Robert Besch, Hendrik Poeck, Simone Willms, Astrid Schwantes, Melanie Kremer, Gerd Sutter, Stefan Endres, Andreas Schmidt, Simon Rothenfusser
Journal: The Journal of Immunology
J Immunol (2012) 188 (1): 394–403.
https://doi.org/10.4049/jimmunol.1100523
Published: 01 January 2012
View article titled, Cytosolic DNA Triggers Mitochondrial Apoptosis via DNA Damage Signaling Proteins Independently of AIM2 and RNA Polymerase III
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Includes: Supplementary data
Journal Articles

Immunostimulatory RNA Blocks Suppression by Regulatory T Cells

David Anz, Viktor H. Koelzer, Stefan Moder, Raffael Thaler, Tobias Schwerd, Katharina Lahl, Tim Sparwasser, Robert Besch, Hendrik Poeck, Veit Hornung, Gunther Hartmann, Simon Rothenfusser, Carole Bourquin, Stefan Endres
Journal: The Journal of Immunology
J Immunol (2010) 184 (2): 939–946.
https://doi.org/10.4049/jimmunol.0901245
Published: 27 December 2009
View article titled, Immunostimulatory RNA Blocks Suppression by Regulatory T Cells
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Includes: Supplementary data
Journal Articles

Selection of Molecular Structure and Delivery of RNA Oligonucleotides to Activate TLR7 versus TLR8 and to Induce High Amounts of IL-12p70 in Primary Human Monocytes

Andrea Ablasser, Hendrik Poeck, David Anz, Michael Berger, Martin Schlee, Sarah Kim, Carole Bourquin, Nadege Goutagny, Zhaozhao Jiang, Katherine A. Fitzgerald, Simon Rothenfusser, Stefan Endres, Gunther Hartmann, Veit Hornung
Journal: The Journal of Immunology
J Immunol (2009) 182 (11): 6824–6833.
https://doi.org/10.4049/jimmunol.0803001
Published: 01 June 2009
View article titled, Selection of Molecular Structure and Delivery of RNA Oligonucleotides to Activate TLR7 versus TLR8 and to Induce High Amounts of IL-12p70 in Primary Human Monocytes
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Journal Articles

The RNA Helicase Lgp2 Inhibits TLR-Independent Sensing of Viral Replication by Retinoic Acid-Inducible Gene-I

Simon Rothenfusser, Nadege Goutagny, Gary DiPerna, Mei Gong, Brian G. Monks, Annett Schoenemeyer, Masahiro Yamamoto, Shizuo Akira, Katherine A. Fitzgerald
Journal: The Journal of Immunology
J Immunol (2005) 175 (8): 5260–5268.
https://doi.org/10.4049/jimmunol.175.8.5260
Published: 15 October 2005
View article titled, The RNA Helicase Lgp2 Inhibits TLR-Independent Sensing of Viral Replication by Retinoic Acid-Inducible Gene-I
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Journal Articles

Replication-Dependent Potent IFN-α Induction in Human Plasmacytoid Dendritic Cells by a Single-Stranded RNA Virus

Veit Hornung, Jörg Schlender, Margit Guenthner-Biller, Simon Rothenfusser, Stefan Endres, Karl-Klaus Conzelmann, Gunther Hartmann
Journal: The Journal of Immunology
J Immunol (2004) 173 (10): 5935–5943.
https://doi.org/10.4049/jimmunol.173.10.5935
Published: 15 November 2004
View article titled, Replication-Dependent Potent IFN-α Induction in Human Plasmacytoid Dendritic Cells by a Single-Stranded RNA Virus
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Journal Articles

IL-12p70-Dependent Th1 Induction by Human B Cells Requires Combined Activation with CD40 Ligand and CpG DNA

Moritz Wagner, Hendrik Poeck, Bernd Jahrsdoerfer, Simon Rothenfusser, Domenik Prell, Barbara Bohle, Evelyn Tuma, Thomas Giese, Joachim W. Ellwart, Stefan Endres, Gunther Hartmann
Journal: The Journal of Immunology
J Immunol (2004) 172 (2): 954–963.
https://doi.org/10.4049/jimmunol.172.2.954
Published: 15 January 2004
View article titled, IL-12p70-Dependent Th1 Induction by Human B Cells Requires Combined Activation with CD40 Ligand and CpG DNA
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Journal Articles

Activation with CpG-A and CpG-B Oligonucleotides Reveals Two Distinct Regulatory Pathways of Type I IFN Synthesis in Human Plasmacytoid Dendritic Cells

Miren Kerkmann, Simon Rothenfusser, Veit Hornung, Andreas Towarowski, Moritz Wagner, Anja Sarris, Thomas Giese, Stefan Endres, Gunther Hartmann
Journal: The Journal of Immunology
J Immunol (2003) 170 (9): 4465–4474.
https://doi.org/10.4049/jimmunol.170.9.4465
Published: 01 May 2003
View article titled, Activation with CpG-A and CpG-B Oligonucleotides Reveals Two Distinct Regulatory Pathways of Type I IFN Synthesis in Human Plasmacytoid Dendritic Cells
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Journal Articles

Mature Dendritic Cells Derived from Human Monocytes Within 48 Hours: A Novel Strategy for Dendritic Cell Differentiation from Blood Precursors

Marc Dauer, Bianca Obermaier, Jan Herten, Carola Haerle, Katrin Pohl, Simon Rothenfusser, Max Schnurr, Stefan Endres, Andreas Eigler
Journal: The Journal of Immunology
J Immunol (2003) 170 (8): 4069–4076.
https://doi.org/10.4049/jimmunol.170.8.4069
Published: 15 April 2003
View article titled, Mature Dendritic Cells Derived from Human Monocytes Within 48 Hours: A Novel Strategy for Dendritic Cell Differentiation from Blood Precursors
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Journal Articles

CpG-A Oligonucleotides Induce a Monocyte-Derived Dendritic Cell-Like Phenotype That Preferentially Activates CD8 T Cells

Anne Krug, Simon Rothenfusser, S. Selinger, C. Bock, M. Kerkmann, J. Battiany, A. Sarris, Thomas Giese, D. Speiser, Stefan Endres, Gunther Hartmann
Journal: The Journal of Immunology
J Immunol (2003) 170 (7): 3468–3477.
https://doi.org/10.4049/jimmunol.170.7.3468
Published: 01 April 2003
View article titled, CpG-A Oligonucleotides Induce a Monocyte-Derived Dendritic Cell-Like Phenotype That Preferentially Activates CD8 T Cells
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Journal Articles

Peritumoral CpG DNA Elicits a Coordinated Response of CD8 T Cells and Innate Effectors to Cure Established Tumors in a Murine Colon Carcinoma Model

Klaus Heckelsmiller, Katharina Rall, Sebastian Beck, Angelika Schlamp, Julia Seiderer, Bernd Jahrsdörfer, Anne Krug, Simon Rothenfusser, Stefan Endres, Gunther Hartmann
Journal: The Journal of Immunology
J Immunol (2002) 169 (7): 3892–3899.
https://doi.org/10.4049/jimmunol.169.7.3892
Published: 01 October 2002
View article titled, Peritumoral CpG DNA Elicits a Coordinated Response of CD8 T Cells and Innate Effectors to Cure Established Tumors in a Murine Colon Carcinoma Model
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Journal Articles

Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides

Veit Hornung, Simon Rothenfusser, Stefanie Britsch, Anne Krug, Bernd Jahrsdörfer, Thomas Giese, Stefan Endres, Gunther Hartmann
Journal: The Journal of Immunology
J Immunol (2002) 168 (9): 4531–4537.
https://doi.org/10.4049/jimmunol.168.9.4531
Published: 01 May 2002
View article titled, Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides
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