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Stefan Lohse
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Journal Articles

Engineering Dimeric EGFR-directed IgA Antibodies Reveals a Central Role of CD147 during Neutrophil-mediated Tumor Cell Killing of Head and Neck Squamous Cancer Cells

Anabel Zwick, Felix Leon Braun, Lennert Jochen Weber, Manuel Linder, Maximilian Linxweiler, Stefan Lohse
Journal: The Journal of Immunology
J Immunol (2024) 213 (2): 148–160.
https://doi.org/10.4049/jimmunol.2300544
Published: 24 May 2024
View article titled, Engineering Dimeric EGFR-directed IgA Antibodies Reveals a Central Role of CD147 during Neutrophil-mediated Tumor Cell Killing of Head and Neck Squamous Cancer Cells
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Includes: Supplementary data
Journal Articles

EGFR antibodies in immunotherapy: complement optimized antibody enhances polymorphonuclear cell mediated killing

Ralf Schwanbeck, Stefanie Derer, Thies Roesner, Christian Kellner, Frank Beurskens, Stefan Lohse, Matthias Peipp, Thomas Valerius
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 142.4.
https://doi.org/10.4049/jimmunol.196.Supp.142.4
Published: 01 May 2016
View article titled, EGFR antibodies in immunotherapy: complement optimized antibody enhances polymorphonuclear cell mediated killing
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Journal Articles

A Complement-Optimized EGFR Antibody Improves Cytotoxic Functions of Polymorphonuclear Cells against Tumor Cells

Stefanie Derer, Michael Cossham, Thies Rösner, Christian Kellner, Frank J. Beurskens, Ralf Schwanbeck, Stefan Lohse, Christian Sina, Matthias Peipp, Thomas Valerius
Journal: The Journal of Immunology
J Immunol (2015) 195 (10): 5077–5087.
https://doi.org/10.4049/jimmunol.1501458
Published: 15 November 2015
View article titled, A Complement-Optimized EGFR Antibody Improves Cytotoxic Functions of Polymorphonuclear Cells against Tumor Cells
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Includes: Supplementary data
Journal Articles

Epidermal Growth Factor Receptor Targeting IgG3 Triggers Complement-Mediated Lysis of Decay-Accelerating Factor Expressing Tumor Cells through the Alternative Pathway Amplification Loop

Thies Rösner, Stefan Lohse, Matthias Peipp, Thomas Valerius, Stefanie Derer
Journal: The Journal of Immunology
J Immunol (2014) 193 (3): 1485–1495.
https://doi.org/10.4049/jimmunol.1400329
Published: 01 August 2014
View article titled, Epidermal Growth Factor Receptor Targeting IgG3 Triggers Complement-Mediated Lysis of Decay-Accelerating Factor Expressing Tumor Cells through the Alternative Pathway Amplification Loop
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Journal Articles

Impact of Epidermal Growth Factor Receptor (EGFR) Cell Surface Expression Levels on Effector Mechanisms of EGFR Antibodies

Stefanie Derer, Philip Bauer, Stefan Lohse, Andreas H. Scheel, Sven Berger, Christian Kellner, Matthias Peipp, Thomas Valerius
Journal: The Journal of Immunology
J Immunol (2012) 189 (11): 5230–5239.
https://doi.org/10.4049/jimmunol.1202037
Published: 01 December 2012
View article titled, Impact of Epidermal Growth Factor Receptor (EGFR) Cell Surface Expression Levels on Effector Mechanisms of EGFR Antibodies
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Journal Articles

Targeting FcαRI on Polymorphonuclear Cells Induces Tumor Cell Killing through Autophagy

Jantine E. Bakema, Sonja H. Ganzevles, Donna M. Fluitsma, Marco W. Schilham, Robert H. J. Beelen, Thomas Valerius, Stefan Lohse, Martin J. Glennie, Jan Paul Medema, Marjolein van Egmond
Journal: The Journal of Immunology
J Immunol (2011) 187 (2): 726–732.
https://doi.org/10.4049/jimmunol.1002581
Published: 15 July 2011
View article titled, Targeting FcαRI on Polymorphonuclear Cells Induces Tumor Cell Killing through Autophagy
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Includes: Multimedia, Supplementary data
Journal Articles

Recombinant Dimeric IgA Antibodies against the Epidermal Growth Factor Receptor Mediate Effective Tumor Cell Killing

Stefan Lohse, Stefanie Derer, Thomas Beyer, Katja Klausz, Matthias Peipp, Jeanette H. W. Leusen, Jan G. J. van de Winkel, Michael Dechant, Thomas Valerius
Journal: The Journal of Immunology
J Immunol (2011) 186 (6): 3770–3778.
https://doi.org/10.4049/jimmunol.1003082
Published: 15 March 2011
View article titled, Recombinant Dimeric IgA Antibodies against the Epidermal Growth Factor Receptor Mediate Effective Tumor Cell Killing
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Includes: Supplementary data
Journal Articles

Human IgG2 Antibodies against Epidermal Growth Factor Receptor Effectively Trigger Antibody-Dependent Cellular Cytotoxicity but, in Contrast to IgG1, Only by Cells of Myeloid Lineage

Tanja Schneider-Merck, Jeroen J. Lammerts van Bueren, Sven Berger, Kai Rossen, Patrick H.C. van Berkel, Stefanie Derer, Thomas Beyer, Stefan Lohse, Wim K. Bleeker, Matthias Peipp, Paul W. H. I. Parren, Jan G. J. van de Winkel, Thomas Valerius, Michael Dechant
Journal: The Journal of Immunology
J Immunol (2010) 184 (1): 512–520.
https://doi.org/10.4049/jimmunol.0900847
Published: 14 December 2009
View article titled, Human IgG2 Antibodies against Epidermal Growth Factor Receptor Effectively Trigger Antibody-Dependent Cellular Cytotoxicity but, in Contrast to IgG1, Only by Cells of Myeloid Lineage
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