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Stefanie Derer
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Journal Articles

Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells

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Annalina Tammen, Stefanie Derer, Ralf Schwanbeck, Thies Rösner, Anna Kretschmer, Frank J. Beurskens, Janine Schuurman, Paul W. H. I. Parren, Thomas Valerius
Journal: The Journal of Immunology
J Immunol (2017) 198 (4): 1585–1594.
https://doi.org/10.4049/jimmunol.1601268
Published: 15 February 2017
View articletitled, Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells
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Journal Articles

Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells

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Patrick J. Engelberts, Marleen Voorhorst, Janine Schuurman, Tom van Meerten, Joost M. Bakker, Tom Vink, Wendy J. M. Mackus, Esther C. W. Breij, Stefanie Derer, Thomas Valerius, Jan G. J. van de Winkel, Paul W. H. I. Parren, Frank J. Beurskens
Journal: The Journal of Immunology
J Immunol (2016) 197 (12): 4829–4837.
https://doi.org/10.4049/jimmunol.1600811
Published: 15 December 2016
View articletitled, Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells
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Includes: Supplementary data
Journal Articles

EGFR antibodies in immunotherapy: complement optimized antibody enhances polymorphonuclear cell mediated killing

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Ralf Schwanbeck, Stefanie Derer, Thies Roesner, Christian Kellner, Frank Beurskens, Stefan Lohse, Matthias Peipp, Thomas Valerius
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 142.4.
https://doi.org/10.4049/jimmunol.196.Supp.142.4
Published: 01 May 2016
View articletitled, EGFR antibodies in immunotherapy: complement optimized antibody enhances polymorphonuclear cell mediated killing
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Journal Articles

A Complement-Optimized EGFR Antibody Improves Cytotoxic Functions of Polymorphonuclear Cells against Tumor Cells

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Stefanie Derer, Michael Cossham, Thies Rösner, Christian Kellner, Frank J. Beurskens, Ralf Schwanbeck, Stefan Lohse, Christian Sina, Matthias Peipp, Thomas Valerius
Journal: The Journal of Immunology
J Immunol (2015) 195 (10): 5077–5087.
https://doi.org/10.4049/jimmunol.1501458
Published: 15 November 2015
View articletitled, A Complement-Optimized EGFR Antibody Improves Cytotoxic Functions of Polymorphonuclear Cells against Tumor Cells
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Includes: Supplementary data
Journal Articles

Epidermal Growth Factor Receptor Targeting IgG3 Triggers Complement-Mediated Lysis of Decay-Accelerating Factor Expressing Tumor Cells through the Alternative Pathway Amplification Loop

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Thies Rösner, Stefan Lohse, Matthias Peipp, Thomas Valerius, Stefanie Derer
Journal: The Journal of Immunology
J Immunol (2014) 193 (3): 1485–1495.
https://doi.org/10.4049/jimmunol.1400329
Published: 01 August 2014
View articletitled, Epidermal Growth Factor Receptor Targeting IgG3 Triggers Complement-Mediated Lysis of Decay-Accelerating Factor Expressing Tumor Cells through the Alternative Pathway Amplification Loop
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Journal Articles

Impact of Epidermal Growth Factor Receptor (EGFR) Cell Surface Expression Levels on Effector Mechanisms of EGFR Antibodies

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Stefanie Derer, Philip Bauer, Stefan Lohse, Andreas H. Scheel, Sven Berger, Christian Kellner, Matthias Peipp, Thomas Valerius
Journal: The Journal of Immunology
J Immunol (2012) 189 (11): 5230–5239.
https://doi.org/10.4049/jimmunol.1202037
Published: 01 December 2012
View articletitled, Impact of Epidermal Growth Factor Receptor (EGFR) Cell Surface Expression Levels on Effector Mechanisms of EGFR Antibodies
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Journal Articles

Recombinant Dimeric IgA Antibodies against the Epidermal Growth Factor Receptor Mediate Effective Tumor Cell Killing

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Stefan Lohse, Stefanie Derer, Thomas Beyer, Katja Klausz, Matthias Peipp, Jeanette H. W. Leusen, Jan G. J. van de Winkel, Michael Dechant, Thomas Valerius
Journal: The Journal of Immunology
J Immunol (2011) 186 (6): 3770–3778.
https://doi.org/10.4049/jimmunol.1003082
Published: 15 March 2011
View articletitled, Recombinant Dimeric IgA Antibodies against the Epidermal Growth Factor Receptor Mediate Effective Tumor Cell Killing
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Includes: Supplementary data
Journal Articles

Human IgG2 Antibodies against Epidermal Growth Factor Receptor Effectively Trigger Antibody-Dependent Cellular Cytotoxicity but, in Contrast to IgG1, Only by Cells of Myeloid Lineage

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Tanja Schneider-Merck, Jeroen J. Lammerts van Bueren, Sven Berger, Kai Rossen, Patrick H.C. van Berkel, Stefanie Derer, Thomas Beyer, Stefan Lohse, Wim K. Bleeker, Matthias Peipp, Paul W. H. I. Parren, Jan G. J. van de Winkel, Thomas Valerius, Michael Dechant
Journal: The Journal of Immunology
J Immunol (2010) 184 (1): 512–520.
https://doi.org/10.4049/jimmunol.0900847
Published: 14 December 2009
View articletitled, Human IgG2 Antibodies against Epidermal Growth Factor Receptor Effectively Trigger Antibody-Dependent Cellular Cytotoxicity but, in Contrast to IgG1, Only by Cells of Myeloid Lineage
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Journal Articles

G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation

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Christian Sina, Olga Gavrilova, Matti Förster, Andreas Till, Stefanie Derer, Friederike Hildebrand, Björn Raabe, Athena Chalaris, Jürgen Scheller, Ateequr Rehmann, Andre Franke, Stephan Ott, Robert Häsler, Susanna Nikolaus, Ulrich R. Fölsch, Stefan Rose-John, Hui-Ping Jiang, Jun Li, Stefan Schreiber, Philip Rosenstiel
Journal: The Journal of Immunology
J Immunol (2009) 183 (11): 7514–7522.
https://doi.org/10.4049/jimmunol.0900063
Published: 01 December 2009
View articletitled, G Protein-Coupled Receptor 43 Is Essential for Neutrophil Recruitment during Intestinal Inflammation
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Includes: Supplementary data