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Stephanie Gras
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Journal Articles

Covalent TCR-pMHC Interactions: A New Mechanism for T Cell Antigen Recognition and T cell Activation

Pirooz Zareie, Christopher Szeto, Rushika Wirasinha, Justin Boxuan Zhang, Andrea Nguyen, Alan Riboldi-Tunnicliffe, Nicole La Gruta, Stephanie Gras, Stephen Daley
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 76.18.
https://doi.org/10.4049/jimmunol.210.Supp.76.18
Published: 01 May 2023
View article titled, Covalent TCR-pMHC Interactions: A New Mechanism for T Cell Antigen Recognition and T cell Activation
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Journal Articles

Cutting Edge: Unconventional CD8+ T Cell Recognition of a Naturally Occurring HLA-A*02:01–Restricted 20mer Epitope

Miranda H. Meeuwsen, Anne K. Wouters, Renate S. Hagedoorn, Michel G. D. Kester, Dennis F. G. Remst, Dirk M. van der Steen, Arnoud de Ru, Peter A. van Veelen, Jamie Rossjohn, Stephanie Gras, J. H. Frederik Falkenburg, Mirjam H. M. Heemskerk
Journal: The Journal of Immunology
J Immunol (2022) 208 (8): 1851–1856.
https://doi.org/10.4049/jimmunol.2101208
Published: 15 April 2022
View article titled, Cutting Edge: Unconventional CD8<sup>+</sup> T Cell Recognition of a Naturally Occurring HLA-A*02:01–Restricted 20mer Epitope
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Includes: Supplementary data
Journal Articles

Pre-existing cellular immunity to SARS-CoV-2 through an immunodominant epitope

In Special Collection:
COVID-19, SARS, and MERS Articles
Emma J Grant, Katie E Lineburg, Srividhya Swaminathan, Demetra S.M. Chatzileontiadou, Christopher Szeto, Hannah Sloane, Archana Panikkar, Jyothy Raju, Pauline Crooks, Sweera Rehan, Andrea T Nguyen, Lea Lekieffre, Michelle Neller, Zhen Wei Marcus Tong, Dhilshan Jayasinghe, Keng Yih Chew, Christian A Lobos, Hanim Halim, Jacqueline M Burrows, Alan Riboldi-Tunnicliffe, Weisan Chen, Lloyd D’Orsogna, Rajiv Khanna, Kirsty R Short, Corey Smith, Stephanie Gras
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 103.02.
https://doi.org/10.4049/jimmunol.206.Supp.103.02
Published: 01 May 2021
View article titled, Pre-existing cellular immunity to SARS-CoV-2 through an immunodominant epitope
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Journal Articles

Overlapping Peptides Elicit Distinct CD8+ T Cell Responses following Influenza A Virus Infection

Lisa M. Assmus, Jing Guan, Ting Wu, Carine Farenc, Xavier Y. X. Sng, Pirooz Zareie, Angela Nguyen, Andrea T. Nguyen, David C. Tscharke, Paul G. Thomas, Jamie Rossjohn, Stephanie Gras, Nathan P. Croft, Anthony W. Purcell, Nicole L. La Gruta
Journal: The Journal of Immunology
J Immunol (2020) 205 (7): 1731–1742.
https://doi.org/10.4049/jimmunol.2000689
Published: 01 October 2020
View article titled, Overlapping Peptides Elicit Distinct CD8<sup>+</sup> T Cell Responses following Influenza A Virus Infection
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Includes: Supplementary data
Journal Articles

A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02–Expressing Individuals

Louise C. Rowntree, Thi H. O. Nguyen, Carine Farenc, Hanim Halim, Luca Hensen, Jamie Rossjohn, Tom C. Kotsimbos, Anthony W. Purcell, Katherine Kedzierska, Stephanie Gras, Nicole A. Mifsud
Journal: The Journal of Immunology
J Immunol (2020) 205 (6): 1524–1534.
https://doi.org/10.4049/jimmunol.2000249
Published: 15 September 2020
View article titled, A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02–Expressing Individuals
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Includes: Supplementary data
Journal Articles

Generating protective immunity to severe influenza disease in Indigenous Australians

Luca Hensen, Patricia Illing, Louise Rowntree, Jennifer Habel, Nicole Mifsud, Marios Koutsakos, Liyen Loh, Carolien van de Sandt, Andrea Nguyen, Stephanie Gras, Steve Rockman, Adrian Miller, Oanh Nguyen, Bridie Clemens, Steven Tong, Anthony Purcell, Katherine Kedzierska
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 93.15.
https://doi.org/10.4049/jimmunol.204.Supp.93.15
Published: 01 May 2020
View article titled, Generating protective immunity to severe influenza disease in Indigenous Australians
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Journal Articles

CD4+ T cell recognition of haemagglutinin epitope across Influenza strains

Andrea T Nguyen, Hannah Sloane, Emma Grant, Christopher Szeto, Dhilshan Jayasinghe, Stephanie Gras
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 93.12.
https://doi.org/10.4049/jimmunol.204.Supp.93.12
Published: 01 May 2020
View article titled, CD4+ T cell recognition of haemagglutinin epitope across Influenza strains
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Journal Articles

CD4+ T cell mediated HLA class II cross-restriction in HIV controllers

Stephanie Gras
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 217.9.
https://doi.org/10.4049/jimmunol.204.Supp.217.9
Published: 01 May 2020
View article titled, CD4+ T cell mediated HLA class II cross-restriction in HIV controllers
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Journal Articles

A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins

Peter Reinink, Adam Shahine, Stephanie Gras, Tan-Yun Cheng, Rachel Farquhar, Kattya Lopez, Sara A. Suliman, Josephine F. Reijneveld, Jérôme Le Nours, Li Lynn Tan, Segundo R. León, Judith Jimenez, Roger Calderon, Leonid Lecca, Megan B. Murray, Jamie Rossjohn, D. Branch Moody, Ildiko Van Rhijn
Journal: The Journal of Immunology
J Immunol (2019) 203 (12): 3395–3406.
https://doi.org/10.4049/jimmunol.1900872
Published: 15 December 2019
View article titled, A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins
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Includes: Supplementary data
Journal Articles

Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses

Louise C. Rowntree, Thi H. O. Nguyen, Hanim Halim, Anthony W. Purcell, Jamie Rossjohn, Stephanie Gras, Tom C. Kotsimbos, Nicole A. Mifsud
Journal: The Journal of Immunology
J Immunol (2018) 200 (12): 3993–4003.
https://doi.org/10.4049/jimmunol.1800010
Published: 15 June 2018
View article titled, Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses
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Journal Articles

Autoreactive CD8+ T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8+ T-cell activation

Linda Wooldridge, David Morgan, James Alexander Pearson, Stephanie Gras, Hugo van den Berg, Anya Lissina, Sian Llewellyn-Lacey, Mark Willis, Tamsin Dockree, James E McLaren, Julia Ekeruche-Makinde, Emma Gostick, Neil Robertson, Jamie Rossjohn, Scott R Burrows, David Price, Susan Wong, Mark Peakman, Ania Skowera, Matthew Clement
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 127.26.
https://doi.org/10.4049/jimmunol.198.Supp.127.26
Published: 01 May 2017
View article titled, Autoreactive CD8<sup>+</sup> T-cells are highly dependent on CD8 for activation and as such targeting CD8 is an effective way of blocking autoreactive CD8<sup>+</sup> T-cell activation
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Journal Articles

Dissection of CD8+ T cell immunodominance hierarchy in human influenza virus infection

Sneha Ashok Sant, Sergio Quinones Parra, Jamie Rossjohn, Stephanie Gras, Liyen Loh, Katherine Kedzierska
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 203.8.
https://doi.org/10.4049/jimmunol.198.Supp.203.8
Published: 01 May 2017
View article titled, Dissection of CD8<sup>+</sup> T cell immunodominance hierarchy in human influenza virus infection
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Journal Articles

HIV-1–Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection

Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter, Paul A. Goepfert
Journal: The Journal of Immunology
J Immunol (2016) 196 (8): 3276–3286.
https://doi.org/10.4049/jimmunol.1502411
Published: 15 April 2016
View article titled, HIV-1–Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection
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Includes: Supplementary data
Journal Articles

T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells

Melissa J. Rist, Kelly M. Hibbert, Nathan P. Croft, Corey Smith, Michelle A. Neller, Jacqueline M. Burrows, John J. Miles, Anthony W. Purcell, Jamie Rossjohn, Stephanie Gras, Scott R. Burrows
Journal: The Journal of Immunology
J Immunol (2015) 194 (10): 4668–4675.
https://doi.org/10.4049/jimmunol.1500233
Published: 15 May 2015
View article titled, T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01<sup>+</sup> Cells
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Journal Articles

The Interaction of KIR3DL1*001 with HLA Class I Molecules Is Dependent upon Molecular Microarchitecture within the Bw4 Epitope

Philippa M. Saunders, Julian P. Vivian, Nikola Baschuk, Travis Beddoe, Jacqueline Widjaja, Geraldine M. O’Connor, Corinne Hitchen, Phillip Pymm, Daniel M. Andrews, Stephanie Gras, Daniel W. McVicar, Jamie Rossjohn, Andrew G. Brooks
Journal: The Journal of Immunology
J Immunol (2015) 194 (2): 781–789.
https://doi.org/10.4049/jimmunol.1402542
Published: 15 January 2015
View article titled, The Interaction of KIR3DL1*001 with HLA Class I Molecules Is Dependent upon Molecular Microarchitecture within the Bw4 Epitope
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Journal Articles

Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans

Jean-Baptiste Reiser, François Legoux, Stéphanie Gras, Eric Trudel, Anne Chouquet, Alexandra Léger, Madalen Le Gorrec, Paul Machillot, Marc Bonneville, Xavier Saulquin, Dominique Housset
Journal: The Journal of Immunology
J Immunol (2014) 193 (12): 5816–5826.
https://doi.org/10.4049/jimmunol.1303084
Published: 15 December 2014
View article titled, Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans
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Includes: Supplementary data
Journal Articles

An Extensive Antigenic Footprint Underpins Immunodominant TCR Adaptability against a Hypervariable Viral Determinant

Usha K. Nivarthi, Stephanie Gras, Lars Kjer-Nielsen, Richard Berry, Isabelle S. Lucet, John J. Miles, Samantha L. Tracy, Anthony W. Purcell, David S. Bowden, Margaret Hellard, Jamie Rossjohn, James McCluskey, Mandvi Bharadwaj
Journal: The Journal of Immunology
J Immunol (2014) 193 (11): 5402–5413.
https://doi.org/10.4049/jimmunol.1401357
Published: 01 December 2014
View article titled, An Extensive Antigenic Footprint Underpins Immunodominant TCR Adaptability against a Hypervariable Viral Determinant
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Includes: Supplementary data
Journal Articles

Structural and Functional Correlates of Enhanced Antiviral Immunity Generated by Heteroclitic CD8 T Cell Epitopes

Jonathan A. Trujillo, Stephanie Gras, Kelly-Anne Twist, Nathan P. Croft, Rudragouda Channappanavar, Jamie Rossjohn, Anthony W. Purcell, Stanley Perlman
Journal: The Journal of Immunology
J Immunol (2014) 192 (11): 5245–5256.
https://doi.org/10.4049/jimmunol.1400111
Published: 01 June 2014
View article titled, Structural and Functional Correlates of Enhanced Antiviral Immunity Generated by Heteroclitic CD8 T Cell Epitopes
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Journal Articles

TCR Bias and Affinity Define Two Compartments of the CD1b–Glycolipid-Specific T Cell Repertoire

Ildiko Van Rhijn, Nicholas A. Gherardin, Anne Kasmar, Wilco de Jager, Daniel G. Pellicci, Lyudmila Kostenko, Li Lynn Tan, Mugdha Bhati, Stephanie Gras, Dale I. Godfrey, Jamie Rossjohn, D. Branch Moody
Journal: The Journal of Immunology
J Immunol (2014) 192 (9): 4054–4060.
https://doi.org/10.4049/jimmunol.1400158
Published: 01 May 2014
View article titled, TCR Bias and Affinity Define Two Compartments of the CD1b–Glycolipid-Specific T Cell Repertoire
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Includes: Supplementary data
Journal Articles

Cutting Edge: CD1a Tetramers and Dextramers Identify Human Lipopeptide–Specific T Cells Ex Vivo

Anne G. Kasmar, Ildiko Van Rhijn, Kelly G. Magalhaes, David C. Young, Tan-Yun Cheng, Marie T. Turner, Andre Schiefner, Ravi C. Kalathur, Ian A. Wilson, Mugdha Bhati, Stephanie Gras, Richard W. Birkinshaw, Li L. Tan, Jamie Rossjohn, John Shires, Søren Jakobsen, John D. Altman, D. Branch Moody
Journal: The Journal of Immunology
J Immunol (2013) 191 (9): 4499–4503.
https://doi.org/10.4049/jimmunol.1301660
Published: 01 November 2013
View article titled, Cutting Edge: CD1a Tetramers and Dextramers Identify Human Lipopeptide–Specific T Cells Ex Vivo
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Includes: Supplementary data