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Stephen H. Clarke
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Journal Articles

Treatment with a CD40 Antagonist Antibody Reverses Severe Proteinuria and Loss of Saliva Production and Restores Glomerular Morphology in Murine Systemic Lupus Erythematosus

Stuart J. Perper, Susan V. Westmoreland, Jozsef Karman, Rachel Twomey, Jane Seagal, Rui Wang, Bradford L. McRae, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2019) 203 (1): 58–75.
https://doi.org/10.4049/jimmunol.1900043
Published: 01 July 2019
View article titled, Treatment with a CD40 Antagonist Antibody Reverses Severe Proteinuria and Loss of Saliva Production and Restores Glomerular Morphology in Murine Systemic Lupus Erythematosus
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Includes: Supplementary data
Journal Articles

Staphylococcus aureus Protein A Disrupts Immunity Mediated by Long-Lived Plasma Cells

Amanda B. Keener, Lance T. Thurlow, SunAh Kang, Nicholas A. Spidale, Stephen H. Clarke, Kenji M. Cunnion, Roland Tisch, Anthony R. Richardson, Barbara J. Vilen
Journal: The Journal of Immunology
J Immunol (2017) 198 (3): 1263–1273.
https://doi.org/10.4049/jimmunol.1600093
Published: 01 February 2017
View article titled, <em>Staphylococcus aureus</em> Protein A Disrupts Immunity Mediated by Long-Lived Plasma Cells
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Includes: Supplementary data
Journal Articles

Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus

SunAh Kang, Jennifer L. Rogers, Andrew J. Monteith, Chuancang Jiang, John Schmitz, Stephen H. Clarke, Teresa K. Tarrant, Young K. Truong, Marilyn Diaz, Yuri Fedoriw, Barbara J. Vilen
Journal: The Journal of Immunology
J Immunol (2016) 196 (10): 4030–4039.
https://doi.org/10.4049/jimmunol.1500418
Published: 15 May 2016
View article titled, Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus
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Includes: Supplementary data
Journal Articles

IgG-Immune Complexes Promote B Cell Memory by Inducing BAFF

SunAh Kang, Amanda B. Keener, Shannon Z. Jones, Robert J. Benschop, Alfredo Caro-Maldonado, Jeffrey C. Rathmell, Stephen H. Clarke, Glenn K. Matsushima, Jason K. Whitmire, Barbara J. Vilen
Journal: The Journal of Immunology
J Immunol (2016) 196 (1): 196–206.
https://doi.org/10.4049/jimmunol.1402527
Published: 01 January 2016
View article titled, IgG-Immune Complexes Promote B Cell Memory by Inducing BAFF
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Includes: Supplementary data
Journal Articles

Receptor Cross-Talk Spatially Restricts p-ERK during TLR4 Stimulation of Autoreactive B Cells

Sang-Ryul Lee, Jennifer A. Rutan, Andrew J. Monteith, Shannon Z. Jones, Sun Ah Kang, Kristen N. Krum, Michelle A. Kilmon, Jose R. Roques, Nikki J. Wagner, Stephen H. Clarke, Barbara J. Vilen
Journal: The Journal of Immunology
J Immunol (2012) 189 (8): 3859–3868.
https://doi.org/10.4049/jimmunol.1200940
Published: 15 October 2012
View article titled, Receptor Cross-Talk Spatially Restricts p-ERK during TLR4 Stimulation of Autoreactive B Cells
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Includes: Supplementary data
Journal Articles

B Cell Receptor Affinity and B Cell Subset Identity Integrate to Define the Effectiveness, Affinity Threshold, and Mechanism of Anergy

Ramiro Diz, Suzanne K. McCray, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2008) 181 (6): 3834–3840.
https://doi.org/10.4049/jimmunol.181.6.3834
Published: 15 September 2008
View article titled, B Cell Receptor Affinity and B Cell Subset Identity Integrate to Define the Effectiveness, Affinity Threshold, and Mechanism of Anergy
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Journal Articles

Transitional B Cells Lose Their Ability to Receptor Edit but Retain Their Potential for Positive and Negative Selection

Hongsheng Wang, Jianxun Feng, Chen-Feng Qi, Zhaoyang Li, Herbert C. Morse, III, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2007) 179 (11): 7544–7552.
https://doi.org/10.4049/jimmunol.179.11.7544
Published: 01 December 2007
View article titled, Transitional B Cells Lose Their Ability to Receptor Edit but Retain Their Potential for Positive and Negative Selection
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Journal Articles

Dissecting the Anti-Desmoglein Autoreactive B Cell Repertoire in Pemphigus Vulgaris Patients

Ye Qian, Luis A. Diaz, Jian Ye, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2007) 178 (9): 5982–5990.
https://doi.org/10.4049/jimmunol.178.9.5982
Published: 01 May 2007
View article titled, Dissecting the Anti-Desmoglein Autoreactive B Cell Repertoire in Pemphigus Vulgaris Patients
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Journal Articles

Anti-desmoglein autoantibody repertoire in pemphigus (B89)

Ye Qian, Stephen H Clarke, Luis A Diaz
Journal: The Journal of Immunology
J Immunol (2007) 178 (1_Supplement): LB18–LB19.
https://doi.org/10.4049/jimmunol.178.Supp.B89
Published: 01 April 2007
View article titled, Anti-desmoglein autoantibody repertoire in pemphigus (B89)
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Journal Articles

EBV Latent Membrane Protein 2A Induces Autoreactive B Cell Activation and TLR Hypersensitivity

Hongsheng Wang, Matilda W. Nicholas, Kara L. Conway, Pradip Sen, Ramiro Diz, Roland M. Tisch, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2006) 177 (5): 2793–2802.
https://doi.org/10.4049/jimmunol.177.5.2793
Published: 01 September 2006
View article titled, EBV Latent Membrane Protein 2A Induces Autoreactive B Cell Activation and TLR Hypersensitivity
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Journal Articles

Early Preplasma Cells Define a Tolerance Checkpoint for Autoreactive B Cells

Donna A. Culton, Brian P. O’Conner, Kara L. Conway, Ramiro Diz, Jennifer Rutan, Barbara J. Vilen, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2006) 176 (2): 790–802.
https://doi.org/10.4049/jimmunol.176.2.790
Published: 15 January 2006
View article titled, Early Preplasma Cells Define a Tolerance Checkpoint for Autoreactive B Cells
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Journal Articles

Cutting Edge: Low-Affinity, Smith Antigen-Specific B Cells Are Tolerized by Dendritic Cells and Macrophages

Michelle A. Kilmon, Jennifer A. Rutan, Stephen H. Clarke, Barbara J. Vilen
Journal: The Journal of Immunology
J Immunol (2005) 175 (1): 37–41.
https://doi.org/10.4049/jimmunol.175.1.37
Published: 01 July 2005
View article titled, Cutting Edge: Low-Affinity, Smith Antigen-Specific B Cells Are Tolerized by Dendritic Cells and Macrophages
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Journal Articles

Interdependence of N Nucleotide Addition and Recombination Site Choice in V(D)J Rearrangement

Thomas B. Kepler, Michelle Borrero, Beth Rugerio, Suzanne K. McCray, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2004) 172 (2): 1311.
https://doi.org/10.4049/jimmunol.172.2.1311
Published: 15 January 2004
View article titled, Interdependence of N Nucleotide Addition and Recombination Site Choice in V(D)J Rearrangement
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Journal Articles

Impaired Clearance of Apoptotic Cells Induces the Activation of Autoreactive Anti-Sm Marginal Zone and B-1 B Cells

Ye Qian, Hongsheng Wang, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2004) 172 (1): 625–635.
https://doi.org/10.4049/jimmunol.172.1.625
Published: 01 January 2004
View article titled, Impaired Clearance of Apoptotic Cells Induces the Activation of Autoreactive Anti-Sm Marginal Zone and B-1 B Cells
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Journal Articles

Evidence for a Ligand-Mediated Positive Selection Signal in Differentiation to a Mature B Cell

Hongsheng Wang, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2003) 171 (12): 6381–6388.
https://doi.org/10.4049/jimmunol.171.12.6381
Published: 15 December 2003
View article titled, Evidence for a Ligand-Mediated Positive Selection Signal in Differentiation to a Mature B Cell
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Journal Articles

Low-Affinity Anti-Smith Antigen B Cells Are Regulated by Anergy as Opposed to Developmental Arrest or Differentiation to B-1

Michelle Borrero, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2002) 168 (1): 13–21.
https://doi.org/10.4049/jimmunol.168.1.13
Published: 01 January 2002
View article titled, Low-Affinity Anti-Smith Antigen B Cells Are Regulated by Anergy as Opposed to Developmental Arrest or Differentiation to B-1
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Journal Articles

A VH12 Transgenic Mouse Exhibits Defects in Pre-B Cell Development and Is Unable to Make IgM+ B Cells

Hongsheng Wang, Jian Ye, Larry W. Arnold, Suzanne K. McCray, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2001) 167 (3): 1254–1262.
https://doi.org/10.4049/jimmunol.167.3.1254
Published: 01 August 2001
View article titled, A V<sub>H</sub>12 Transgenic Mouse Exhibits Defects in Pre-B Cell Development and Is Unable to Make IgM<sup>+</sup> B Cells
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Journal Articles

Anti-Sm B Cell Differentiation in Ig Transgenic MRL/Mp-lpr/lpr Mice: Altered Differentiation and an Accelerated Response

Sandra Santulli-Marotto, Ye Qian, Stacy Ferguson, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2001) 166 (8): 5292–5299.
https://doi.org/10.4049/jimmunol.166.8.5292
Published: 15 April 2001
View article titled, Anti-Sm B Cell Differentiation in Ig Transgenic MRL/Mp-<em>lpr</em>/<em>lpr</em> Mice: Altered Differentiation and an Accelerated Response
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Journal Articles

Lupus-Specific Antiribonucleoprotein B Cell Tolerance in Nonautoimmune Mice Is Maintained by Differentiation to B-1 and Governed by B Cell Receptor Signaling Thresholds

Ye Qian, Carlos Santiago, Michelle Borrero, Thomas F. Tedder, Stephen H. Clarke
Journal: The Journal of Immunology
J Immunol (2001) 166 (4): 2412–2419.
https://doi.org/10.4049/jimmunol.166.4.2412
Published: 15 February 2001
View article titled, Lupus-Specific Antiribonucleoprotein B Cell Tolerance in Nonautoimmune Mice Is Maintained by Differentiation to B-1 and Governed by B Cell Receptor Signaling Thresholds
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Journal Articles

Restriction in Vκ Gene Use and Antigen Selection in Anti-Myeloperoxidase Response in Mice

Hitendra S. Jethwa, Stephen H. Clarke, Yoshie Itoh-Lindstrom, Ronald J. Falk, J. Charles Jennette, Patrick H. Nachman
Journal: The Journal of Immunology
J Immunol (2000) 165 (7): 3890–3897.
https://doi.org/10.4049/jimmunol.165.7.3890
Published: 01 October 2000
View article titled, Restriction in Vκ Gene Use and Antigen Selection in Anti-Myeloperoxidase Response in Mice
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