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Stephen T. Holgate
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Journal Articles

Contribution of Bronchial Fibroblasts to the Antiviral Response in Asthma

Nicole Bedke, Hans Michael Haitchi, Mara Xatzipsalti, Stephen T. Holgate, Donna E. Davies
Journal: The Journal of Immunology
J Immunol (2009) 182 (6): 3660–3667.
DOI: https://doi.org/10.4049/jimmunol.0802471
Published: 15 March 2009
View article titled, Contribution of Bronchial Fibroblasts to the Antiviral Response in Asthma
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Includes: Supplementary data
Journal Articles

IL-4 Receptor α Is an Important Modulator of IL-4 and IL-13 Receptor Binding: Implications for the Development of Therapeutic Targets

Allison-Lynn Andrews, John W. Holloway, Stephen T. Holgate, Donna E. Davies
Journal: The Journal of Immunology
J Immunol (2006) 176 (12): 7456–7461.
DOI: https://doi.org/10.4049/jimmunol.176.12.7456
Published: 15 June 2006
View article titled, IL-4 Receptor α Is an Important Modulator of IL-4 and IL-13 Receptor Binding: Implications for the Development of Therapeutic Targets
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Journal Articles

NF-κB and TNF-α: A Positive Autocrine Loop in Human Lung Mast Cells?

William R. Coward, Yoshimichi Okayama, Hironori Sagara, Susan J. Wilson, Stephen T. Holgate, Martin K. Church
Journal: The Journal of Immunology
J Immunol (2002) 169 (9): 5287–5293.
DOI: https://doi.org/10.4049/jimmunol.169.9.5287
Published: 01 November 2002
View article titled, NF-κB and TNF-α: A Positive Autocrine Loop in Human Lung Mast Cells?
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Journal Articles

Cooperative Effects of Th2 Cytokines and Allergen on Normal and Asthmatic Bronchial Epithelial Cells

James L. Lordan, Fabio Bucchieri, Audrey Richter, Athanassias Konstantinidis, John W. Holloway, Matthew Thornber, Sarah M. Puddicombe, Diana Buchanan, Susan J. Wilson, Ratko Djukanović, Stephen T. Holgate, Donna E. Davies
Journal: The Journal of Immunology
J Immunol (2002) 169 (1): 407–414.
DOI: https://doi.org/10.4049/jimmunol.169.1.407
Published: 01 July 2002
View article titled, Cooperative Effects of Th2 Cytokines and Allergen on Normal and Asthmatic Bronchial Epithelial Cells
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Journal Articles

Role of B7-CD28/CTLA-4 Costimulation and NF-κB in Allergen-Induced T Cell Chemotaxis by IL-16 and RANTES

Rabia Hidi, Vanessa Riches, Musa Al-Ali, William W. Cruikshank, David M. Center, Stephen T. Holgate, Ratko Djukanović
Journal: The Journal of Immunology
J Immunol (2000) 164 (1): 412–418.
DOI: https://doi.org/10.4049/jimmunol.164.1.412
Published: 01 January 2000
View article titled, Role of B7-CD28/CTLA-4 Costimulation and NF-κB in Allergen-Induced T Cell Chemotaxis by IL-16 and RANTES
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Journal Articles

Essential Role for Both CD80 and CD86 Costimulation, But Not CD40 Interactions, in Allergen-Induced Th2 Cytokine Production from Asthmatic Bronchial Tissue: Role for αβ, But Not γδ, T Cells

Zeina H. Jaffar, Luminita Stanciu, Anita Pandit, James Lordan, Stephen T. Holgate, Kevan Roberts
Journal: The Journal of Immunology
J Immunol (1999) 163 (11): 6283–6291.
DOI: https://doi.org/10.4049/jimmunol.163.11.6283
Published: 01 December 1999
View article titled, Essential Role for Both CD80 and CD86 Costimulation, But Not CD40 Interactions, in Allergen-Induced Th2 Cytokine Production from Asthmatic Bronchial Tissue: Role for αβ, But Not γδ, T Cells
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Journal Articles

IL-5 Increases Expression of 5-Lipoxygenase-Activating Protein and Translocates 5-Lipoxygenase to the Nucleus in Human Blood Eosinophils

Andrew S. Cowburn, Stephen T. Holgate, Anthony P. Sampson
Journal: The Journal of Immunology
J Immunol (1999) 163 (1): 456–465.
DOI: https://doi.org/10.4049/jimmunol.163.1.456
Published: 01 July 1999
View article titled, IL-5 Increases Expression of 5-Lipoxygenase-Activating Protein and Translocates 5-Lipoxygenase to the Nucleus in Human Blood Eosinophils
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Journal Articles

Regulation of Pulmonary T Cell Responses to Inhaled Antigen: Role in Th1- and Th2-Mediated Inflammation

Shiour-Ching Lee, Zeina H. Jaffar, Kong-Sang Wan, Stephen T. Holgate, Kevan Roberts
Journal: The Journal of Immunology
J Immunol (1999) 162 (11): 6867–6879.
DOI: https://doi.org/10.4049/jimmunol.162.11.6867
Published: 01 June 1999
View article titled, Regulation of Pulmonary T Cell Responses to Inhaled Antigen: Role in Th1- and Th2-Mediated Inflammation
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Journal Articles

The Role of Mast Cell Tryptase in Regulating Endothelial Cell Proliferation, Cytokine Release, and Adhesion Molecule Expression: Tryptase Induces Expression of mRNA for IL-1β and IL-8 and Stimulates the Selective Release of IL-8 from Human Umbilical Vein Endothelial Cells

Steven J. Compton, Jennifer A. Cairns, Stephen T. Holgate, Andrew F. Walls
Journal: The Journal of Immunology
J Immunol (1998) 161 (4): 1939–1946.
DOI: https://doi.org/10.4049/jimmunol.161.4.1939
Published: 15 August 1998
View article titled, The Role of Mast Cell Tryptase in Regulating Endothelial Cell Proliferation, Cytokine Release, and Adhesion Molecule Expression: Tryptase Induces Expression of mRNA for IL-1β and IL-8 and Stimulates the Selective Release of IL-8 from Human Umbilical Vein Endothelial Cells
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Journal Articles

Effects of Indomethacin on Cyclic Nucleotide Levels and Histamine Release from Rat Serosal Mast Cells

Robert A. Lewis, Stephen T. Holgate, L. Jackson Roberts, II, James F. Maguire, John A. Oates, K. Frank Austen
Journal: The Journal of Immunology
J Immunol (1979) 123 (4): 1663–1668.
DOI: https://doi.org/10.4049/jimmunol.123.4.1663
Published: 01 October 1979
View article titled, Effects of Indomethacin on Cyclic Nucleotide Levels and Histamine Release from Rat Serosal Mast Cells
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