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Steven G. Reed
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Journal Articles

Computationally Designed Bispecific MD2/CD14 Binding Peptides Show TLR4 Agonist Activity

Amit Michaeli, Shaul Mezan, Andreas Kühbacher, Doris Finkelmeier, Maayan Elias, Maria Zatsepin, Steven G. Reed, Malcolm S. Duthie, Steffen Rupp, Immanuel Lerner, Anke Burger-Kentischer
Journal: The Journal of Immunology
J Immunol (2018) 201 (11): 3383–3391.
https://doi.org/10.4049/jimmunol.1800380
Published: 01 December 2018
View article titled, Computationally Designed Bispecific MD2/CD14 Binding Peptides Show TLR4 Agonist Activity
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Includes: Supplementary data
Journal Articles

Use of GLA-nanoalum as an effective adjuvant for a therapeutic ID93 TB vaccine

Susan L. Baldwin, Sasha E. Larsen, Valerie A. Reese, Tiffany Pecor, Brian Granger, Amit Khandhar, Christopher B. Fox, Steven G. Reed, Rhea N. Coler
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 180.21.
https://doi.org/10.4049/jimmunol.200.Supp.180.21
Published: 01 May 2018
View article titled, Use of GLA-nanoalum as an effective adjuvant for a therapeutic ID93 TB vaccine
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Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization

Simon D. van Haren, David J. Dowling, Willemina Foppen, Dennis Christensen, Peter Andersen, Steven G. Reed, Robert M. Hershberg, Lindsey R. Baden, Ofer Levy
Journal: The Journal of Immunology
J Immunol (2016) 197 (11): 4413–4424.
https://doi.org/10.4049/jimmunol.1600282
Published: 01 December 2016
View article titled, Age-Specific Adjuvant Synergy: Dual TLR7/8 and Mincle Activation of Human Newborn Dendritic Cells Enables Th1 Polarization
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Includes: Supplementary data
Journal Articles

IL-18 and Subcapsular Lymph Node Macrophages are Essential for Enhanced B Cell Responses with TLR4 Agonist Adjuvants

Anthony L. Desbien, Natasha Dubois Cauwelaert, Steven J. Reed, Hilton R. Bailor, Hong Liang, Darrick Carter, Malcolm S. Duthie, Christopher B. Fox, Steven G. Reed, Mark T. Orr
Journal: The Journal of Immunology
J Immunol (2016) 197 (11): 4351–4359.
https://doi.org/10.4049/jimmunol.1600993
Published: 01 December 2016
View article titled, IL-18 and Subcapsular Lymph Node Macrophages are Essential for Enhanced B Cell Responses with TLR4 Agonist Adjuvants
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Includes: Supplementary data
Journal Articles

The TLR4 agonist vaccine adjuvant, GLA-SE, requires canonical and atypical mechanisms of action for TH1 induction

Natasha Dubois Cauwelaert, Anthony L Desbien, Thomas E Hudson, Samuel O Pine, Steven G Reed, Rhea N. Coler, Mark T Orr
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 75.7.
https://doi.org/10.4049/jimmunol.196.Supp.75.7
Published: 01 May 2016
View article titled, The TLR4 agonist vaccine adjuvant, GLA-SE, requires canonical and atypical mechanisms of action for T<sub>H</sub>1 induction
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Journal Articles

Increased protection and decreased lung immunopathology induced by the ID93/GLA-SE vaccine candidate following infection with Mycobacterium tuberculosis HN878.

Susan L Baldwin, Valerie A. Reese, Po-wei D. Huang, Elyse A. Beebe, Brendan K. Podell, Steven G. Reed, Rhea N. Coler
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 76.20.
https://doi.org/10.4049/jimmunol.196.Supp.76.20
Published: 01 May 2016
View article titled, Increased protection and decreased lung immunopathology induced by the ID93/GLA-SE vaccine candidate following infection with <em>Mycobacterium tuberculosis</em> HN878.
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Journal Articles

Mechanisms of activity of the combination TLR4 agonist and emulsion adjuvant GLA-SE

Mark T Orr, Anthony L Desbien, Natasha D Cauwelaert, Steven G Reed
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 75.2.
https://doi.org/10.4049/jimmunol.196.Supp.75.2
Published: 01 May 2016
View article titled, Mechanisms of activity of the combination TLR4 agonist and emulsion adjuvant GLA-SE
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Journal Articles

Immune Subdominant Antigens as Vaccine Candidates against Mycobacterium tuberculosis

Mark T. Orr, Gregory C. Ireton, Elyse A. Beebe, Po-Wei D. Huang, Valerie A. Reese, David Argilla, Rhea N. Coler, Steven G. Reed
Journal: The Journal of Immunology
J Immunol (2014) 193 (6): 2911–2918.
https://doi.org/10.4049/jimmunol.1401103
Published: 15 September 2014
View article titled, Immune Subdominant Antigens as Vaccine Candidates against <em>Mycobacterium tuberculosis</em>
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Includes: Supplementary data
Journal Articles

Protection against Tuberculosis with Homologous or Heterologous Protein/Vector Vaccine Approaches Is Not Dependent on CD8+ T Cells

Susan L. Baldwin, Lance K. Ching, Samuel O. Pine, Magdalini Moutaftsi, Elyse Lucas, Aarthy Vallur, Mark T. Orr, Sylvie Bertholet, Steven G. Reed, Rhea N. Coler
Journal: The Journal of Immunology
J Immunol (2013) 191 (5): 2514–2525.
https://doi.org/10.4049/jimmunol.1301161
Published: 01 September 2013
View article titled, Protection against Tuberculosis with Homologous or Heterologous Protein/Vector Vaccine Approaches Is Not Dependent on CD8<sup>+</sup> T Cells
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Includes: Supplementary data
Journal Articles

The Importance of Adjuvant Formulation in the Development of a Tuberculosis Vaccine

Susan L. Baldwin, Sylvie Bertholet, Valerie A. Reese, Lance K. Ching, Steven G. Reed, Rhea N. Coler
Journal: The Journal of Immunology
J Immunol (2012) 188 (5): 2189–2197.
https://doi.org/10.4049/jimmunol.1102696
Published: 01 March 2012
View article titled, The Importance of Adjuvant Formulation in the Development of a Tuberculosis Vaccine
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Includes: Supplementary data
Journal Articles

Applying TLR Synergy in Immunotherapy: Implications in Cutaneous Leishmaniasis

Vanitha S. Raman, Ajay Bhatia, Alex Picone, Jacqueline Whittle, Hilton R. Bailor, Joanne O’Donnell, Sowmya Pattabhi, Jeffrey A. Guderian, Raodoh Mohamath, Malcolm S. Duthie, Steven G. Reed
Journal: The Journal of Immunology
J Immunol (2010) 185 (3): 1701–1710.
https://doi.org/10.4049/jimmunol.1000238
Published: 01 August 2010
View article titled, Applying TLR Synergy in Immunotherapy: Implications in Cutaneous Leishmaniasis
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Includes: Supplementary data
Journal Articles

Immunoglobulin G and M Detection for Leprosy Diagnosis (129.18)

Malcolm S Duthie, Isabela M B Goulart, Steven G Reed, Janaina Lobato, Luiz R Goulart
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 129.18.
https://doi.org/10.4049/jimmunol.182.Supp.129.18
Published: 01 April 2009
View article titled, Immunoglobulin G and M Detection for Leprosy Diagnosis (129.18)
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Journal Articles

Enhanced T helper 1 (Th1) responses with Fluzone® adjuvanted with a synthetic TLR4 agonist in an emulsion (45.15)

Susan L. Baldwin, Narek Shaverdian, Yasuyuki Goto, Malcolm S. Duthie, Tara Evers, Farah Mompoint, Tom S. Vedvick, Sylvie Bertholet, Rhea N. Coler, Steven G. Reed
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 45.15.
https://doi.org/10.4049/jimmunol.182.Supp.45.15
Published: 01 April 2009
View article titled, Enhanced T helper 1 (Th1) responses with Fluzone® adjuvanted with a synthetic TLR4 agonist in an emulsion (45.15)
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Journal Articles

Cross-protective humoral and cellular immune responses to A/H3N2 drifted influenza viruses following immunization with Fluzone® with a synthetic TLR4 agonist formulation (45.11)

Narek Shaverdian, Susan L. Baldwin, Steven J. Reed, Vanitha Raman, Yasu Goto, Farah Mompoint, Thomas S. Vedvick, Christopher H. Clegg, Rhea N. Coler, Steven G. Reed
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 45.11.
https://doi.org/10.4049/jimmunol.182.Supp.45.11
Published: 01 April 2009
View article titled, Cross-protective humoral and cellular immune responses to A/H3N2 drifted influenza viruses following immunization with Fluzone® with a synthetic TLR4 agonist formulation (45.11)
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Journal Articles

The role of IL-17 in the protective immune response to Mycobacterium tuberculosis (44.18)

Hillarie Plessner Windish, John Zheng, Sylvie Bertholet, Susan L Baldwin, Gregory C Ireton, Tom Vedvick, Steven G Reed, Rhea N Coler
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 44.18.
https://doi.org/10.4049/jimmunol.182.Supp.44.18
Published: 01 April 2009
View article titled, The role of IL-17 in the protective immune response to Mycobacterium tuberculosis (44.18)
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Journal Articles

Identification of Human T Cell Antigens for the Development of Vaccines against Mycobacterium tuberculosis

Sylvie Bertholet, Gregory C. Ireton, Maria Kahn, Jeffrey Guderian, Raodoh Mohamath, Nicole Stride, Elsa M. Laughlin, Susan L. Baldwin, Thomas S. Vedvick, Rhea N. Coler, Steven G. Reed
Journal: The Journal of Immunology
J Immunol (2008) 181 (11): 7948–7957.
https://doi.org/10.4049/jimmunol.181.11.7948
Published: 01 December 2008
View article titled, Identification of Human T Cell Antigens for the Development of Vaccines against <em>Mycobacterium tuberculosis</em>
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Journal Articles

Cloning of the Gene Encoding a Protective Mycobacterium tuberculosis Secreted Protein Detected In Vivo during the Initial Phases of the Infectious Process

Sandeep Mukherjee, Suely S. Kashino, Yanni Zhang, Nada Daifalla, Virmondes Rodrigues, Jr, Steven G. Reed, Antonio Campos-Neto
Journal: The Journal of Immunology
J Immunol (2005) 175 (8): 5298–5305.
https://doi.org/10.4049/jimmunol.175.8.5298
Published: 15 October 2005
View article titled, Cloning of the Gene Encoding a Protective <em>Mycobacterium tuberculosis</em> Secreted Protein Detected In Vivo during the Initial Phases of the Infectious Process
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Journal Articles

Differential Immune Responses and Protective Efficacy Induced by Components of a Tuberculosis Polyprotein Vaccine, Mtb72F, Delivered as Naked DNA or Recombinant Protein

Yasir A. W. Skeiky, Mark R. Alderson, Pamela J. Ovendale, Jeffrey A. Guderian, Lise Brandt, Davin C. Dillon, Antonio Campos-Neto, Yves Lobet, Wilfried Dalemans, Ian M. Orme, Steven G. Reed
Journal: The Journal of Immunology
J Immunol (2004) 172 (12): 7618–7628.
https://doi.org/10.4049/jimmunol.172.12.7618
Published: 15 June 2004
View article titled, Differential Immune Responses and Protective Efficacy Induced by Components of a Tuberculosis Polyprotein Vaccine, Mtb72F, Delivered as Naked DNA or Recombinant Protein
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Journal Articles

Vaccination with the T Cell Antigen Mtb 8.4 Protects Against Challenge with Mycobacterium tuberculosis

Rhea N. Coler, Antonio Campos-Neto, Pamela Ovendale, Fiona H. Day, Steven P. Fling, Liqing Zhu, Natalya Serbina, JoAnne L. Flynn, Steven G. Reed, Mark R. Alderson
Journal: The Journal of Immunology
J Immunol (2001) 166 (10): 6227–6235.
https://doi.org/10.4049/jimmunol.166.10.6227
Published: 15 May 2001
View article titled, Vaccination with the T Cell Antigen Mtb 8.4 Protects Against Challenge with <em>Mycobacterium tuberculosis</em>
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Classically Restricted Human CD8+ T Lymphocytes Derived from Mycobacterium tuberculosis-Infected Cells: Definition of Antigenic Specificity

David M. Lewinsohn, Liqing Zhu, Valerie J. Madison, Davin C. Dillon, Steven P. Fling, Steven G. Reed, Kenneth H. Grabstein, Mark R. Alderson
Journal: The Journal of Immunology
J Immunol (2001) 166 (1): 439–446.
https://doi.org/10.4049/jimmunol.166.1.439
Published: 01 January 2001
View article titled, Classically Restricted Human CD8<sup>+</sup> T Lymphocytes Derived from <em>Mycobacterium tuberculosis</em>-Infected Cells: Definition of Antigenic Specificity
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