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Steven M. Varga
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Journal Articles

Imaging of lung resident memory CD8 +T cells reveals antigen-specific early protective responses during secondary infection

Stephanie van de Wall, Scott M. Anthony, Steven M. Varga, Ryan A. Langlois, Dietmar Zehn, Vladimir P. Badovinac, John T. Harty
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 236.13.
https://doi.org/10.4049/jimmunol.210.Supp.236.13
Published: 01 May 2023
View article titled, Imaging of lung resident memory CD8 <sup>+</sup>T cells reveals antigen-specific early protective responses during secondary infection
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Journal Articles

NF-κB activation and pro-inflammatory cytokine production is modulated by a single point-mutation in the RSV fusion protein

Austin Bruce Santhin, Kody Waldstein, Steven M Varga
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 75.40.
https://doi.org/10.4049/jimmunol.210.Supp.75.40
Published: 01 May 2023
View article titled, NF-κB activation and pro-inflammatory cytokine production is modulated by a single point-mutation in the RSV fusion protein
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Journal Articles

Cutting Edge: Influenza-Induced CD11alo Airway CD103+ Tissue Resident Memory T Cells Exhibit Compromised IFN-γ Production after In Vivo TCR Stimulation

Stephanie van de Wall, Sequoia Crooks, Steven M. Varga, Vladimir P. Badovinac, John T. Harty
Journal: The Journal of Immunology
J Immunol (2023) 210 (8): 1025–1030.
https://doi.org/10.4049/jimmunol.2200931
Published: 13 March 2023
View article titled, Cutting Edge: Influenza-Induced CD11a<sup>lo</sup> Airway CD103<sup>+</sup> Tissue Resident Memory T Cells Exhibit Compromised IFN-γ Production after In Vivo TCR Stimulation
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Includes: Supplementary data
Journal Articles

Robust efficacy and long-lasting humoral immunity induced by a respiratory syncytial virus prefusion F-based nanoparticle vaccine in genetically diverse animal models

Laura Stephens, Kathleen A. Ross, Jason S. McLellan, Balaji Narasimhan, Steven M Varga
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 64.14.
https://doi.org/10.4049/jimmunol.208.Supp.64.14
Published: 01 May 2022
View article titled, Robust efficacy and long-lasting humoral immunity induced by a respiratory syncytial virus prefusion F-based nanoparticle vaccine in genetically diverse animal models
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Journal Articles

E3 Ubiquitin Ligase Cbl-b Inhibits Type 2 Innate Lymphoid Cell Development by Targeting ST2 for Ubiquitination

Hui Guo, Ling Huang, Kody Waldstein, Steven M Varga, Jian Zhang
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 109.13.
https://doi.org/10.4049/jimmunol.208.Supp.109.13
Published: 01 May 2022
View article titled, E3 Ubiquitin Ligase Cbl-b Inhibits Type 2 Innate Lymphoid Cell Development by Targeting ST2 for Ubiquitination
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Journal Articles

Alveolar macrophages act as an early viral sponge inducing long-lived functional enhancement

Kody Waldstein, Stephanie van de Wall, Scott Anthony, John T Harty, Steven M Varga
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 126.05.
https://doi.org/10.4049/jimmunol.208.Supp.126.05
Published: 01 May 2022
View article titled, Alveolar macrophages act as an early viral sponge inducing long-lived functional enhancement
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Journal Articles

Respiratory Syncytial Virus Provides Protection against a Subsequent Influenza A Virus Infection

Stacey M. Hartwig, Ann M. Miller, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2022) 208 (3): 720–731.
https://doi.org/10.4049/jimmunol.2000751
Published: 01 February 2022
View article titled, Respiratory Syncytial Virus Provides Protection against a Subsequent Influenza A Virus Infection
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Includes: Supplementary data
Journal Articles

Prefusion F–Based Polyanhydride Nanovaccine Induces Both Humoral and Cell-Mediated Immunity Resulting in Long-Lasting Protection against Respiratory Syncytial Virus

Laura M. Stephens, Kathleen A. Ross, Kody A. Waldstein, Kevin L. Legge, Jason S. McLellan, Balaji Narasimhan, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2021) 206 (9): 2122–2134.
https://doi.org/10.4049/jimmunol.2100018
Published: 01 May 2021
View article titled, Prefusion F–Based Polyanhydride Nanovaccine Induces Both Humoral and Cell-Mediated Immunity Resulting in Long-Lasting Protection against Respiratory Syncytial Virus
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Includes: Supplementary data
Journal Articles

Genetic Variation in the RSV fusion protein controls strain-dependent inflammasome activation and the development of a pathogenic Th17 response

Kody Waldstein, Kayla Weiss, Stacey Hartwig, Steven M Varga
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 20.02.
https://doi.org/10.4049/jimmunol.206.Supp.20.02
Published: 01 May 2021
View article titled, Genetic Variation in the RSV fusion protein controls strain-dependent inflammasome activation and the development of a pathogenic Th17 response
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Journal Articles

Prefusion F-based polyanhydride nanovaccine induces robust humoral and cell-mediated immunity resulting in long-lasting protection against respiratory syncytial virus

Laura Stephens, Kathleen A. Ross, Kevin L. Legge, Jason S. McLellan, Balaji Narasimhan, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 59.04.
https://doi.org/10.4049/jimmunol.206.Supp.59.04
Published: 01 May 2021
View article titled, Prefusion F-based polyanhydride nanovaccine induces robust humoral and cell-mediated immunity resulting in long-lasting protection against respiratory syncytial virus
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Journal Articles

AAI Curriculum Ad Hoc Committee Presentation: The Development of AAI Recommendations for an Undergraduate Course in Immunology

Eyal Amiel, Michelle Anne Swanson-Mungerson, Andrea Bottaro, William H Carr, Steven M Varga, Nandita Bose, Julie M Jameson, Edith Porter
Journal: The Journal of Immunology
J Immunol (2021) 206 (1_Supplement): 54.09.
https://doi.org/10.4049/jimmunol.206.Supp.54.09
Published: 01 May 2021
View article titled, AAI Curriculum Ad Hoc Committee Presentation: The Development of AAI Recommendations for an Undergraduate Course in Immunology
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Journal Articles

Genetic variation in the RSV fusion protein controls RSV strain-dependent inflammasome activation and the development of a pathogenic Th17 response

Kody Waldstein, Kayla A Weiss, Stacey M Hartwig, Steven M Varga
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 93.1.
https://doi.org/10.4049/jimmunol.204.Supp.93.1
Published: 01 May 2020
View article titled, Genetic variation in the RSV fusion protein controls RSV strain-dependent inflammasome activation and the development of a pathogenic Th17 response
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Journal Articles

E3 Ubiquitin Ligase Cbl-b Inhibits Type 2 Innate Lymphoid Cell Development by Targeting ST2 for Ubiquitination

Hui Guo, Ling Huang, Na Tang, Kody Waldstein, Steven M Varga, Jian Zhang
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 147.25.
https://doi.org/10.4049/jimmunol.204.Supp.147.25
Published: 01 May 2020
View article titled, E3 Ubiquitin Ligase Cbl-b Inhibits Type 2 Innate Lymphoid Cell Development by Targeting ST2 for Ubiquitination
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Journal Articles

Resident memory CD8 T cells patrol the lung and mediate early protective immunity

Scott M Anthony, Ryan A Langlois, Steven M Varga, John T Harty
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 85.1.
https://doi.org/10.4049/jimmunol.204.Supp.85.1
Published: 01 May 2020
View article titled, Resident memory CD8 T cells patrol the lung and mediate early protective immunity
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Journal Articles

Polyanhydride-based RSV prefusion F nanoparticle vaccine establishes lasting protection mediated by humoral and cellular immune responses

Laura Stephens, Kathleen A. Ross, Stacey M. Hartwig, Jason S. McLellan, Balaji Narasimhan, Kevin L. Legge, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 166.3.
https://doi.org/10.4049/jimmunol.204.Supp.166.3
Published: 01 May 2020
View article titled, Polyanhydride-based RSV prefusion F nanoparticle vaccine establishes lasting protection mediated by humoral and cellular immune responses
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Journal Articles

Vaccination with a Single-Cycle Respiratory Syncytial Virus Is Immunogenic and Protective in Mice

Megan E. Schmidt, Antonius G. P. Oomens, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2019) 202 (11): 3234–3245.
https://doi.org/10.4049/jimmunol.1900050
Published: 01 June 2019
View article titled, Vaccination with a Single-Cycle Respiratory Syncytial Virus Is Immunogenic and Protective in Mice
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Includes: Supplementary data
Journal Articles

Robust immune response and protection generated by a polyanhydride-based nanoparticle vaccine utilizing the RSV prefusion F protein and/or M protein

Laura Stephens, Kathleen A. Ross, Stacey M. Hartwig, Jason S. McLellan, Balaji Narasimhan, Kevin L. Legge, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 139.11.
https://doi.org/10.4049/jimmunol.202.Supp.139.11
Published: 01 May 2019
View article titled, Robust immune response and protection generated by a polyanhydride-based nanoparticle vaccine utilizing the RSV prefusion F protein and/or M protein
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Journal Articles

Respiratory syncytial virus strains differentially activate the inflammasome eliciting a pathogenic Th17 response

Kody Waldstein, Kayla A. Weiss, Stacey Hartwig, Hannah Quick, Barun Poudel, Prajwal Gurung, Steven M Varga
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 198.3.
https://doi.org/10.4049/jimmunol.202.Supp.198.3
Published: 01 May 2019
View article titled, Respiratory syncytial virus strains differentially activate the inflammasome eliciting a pathogenic Th17 response
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Journal Articles

Lung-draining lymph-node-resident memory CD8 T cells mediate local protective immunity

Scott M Anthony, Natalija Van Braeckel-Budimir, Steven Moioffer, Stacey M Hartwig, Steven M Varga, Vladimir P Badovinac, John T Harty
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 198.7.
https://doi.org/10.4049/jimmunol.202.Supp.198.7
Published: 01 May 2019
View article titled, Lung-draining lymph-node-resident memory CD8 T cells mediate local protective immunity
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Journal Articles

Single-cycle respiratory syncytial virus infection induces robust adaptive immune responses and reduces disease severity in mice

Megan E. Schmidt, Antonius G.P. Oomens, Steven M. Varga
Journal: The Journal of Immunology
J Immunol (2018) 200 (1_Supplement): 60.2.
https://doi.org/10.4049/jimmunol.200.Supp.60.2
Published: 01 May 2018
View article titled, Single-cycle respiratory syncytial virus infection induces robust adaptive immune responses and reduces disease severity in mice
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