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T R Malek
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Journal Articles

Distribution of Ly-6C on lymphocyte subsets: I. Influence of allotype on T lymphocyte expression.

A J Schlueter, T R Malek, C N Hostetler, P A Smith, P deVries, T J Waldschmidt
Journal: The Journal of Immunology
J Immunol (1997) 158 (9): 4211–4222.
DOI: https://doi.org/10.4049/jimmunol.158.9.4211
Published: 01 May 1997
View article titled, Distribution of Ly-6C on lymphocyte subsets: I. Influence of allotype on T lymphocyte expression.
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Journal Articles

The common gamma-chain of cytokine receptors regulates intrathymic T cell development at multiple stages.

Y W He, H Nakajima, W J Leonard, B Adkins, T R Malek
Journal: The Journal of Immunology
J Immunol (1997) 158 (6): 2592–2599.
DOI: https://doi.org/10.4049/jimmunol.158.6.2592
Published: 15 March 1997
View article titled, The common gamma-chain of cytokine receptors regulates intrathymic T cell development at multiple stages.
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Journal Articles

Generation of primary tumor-specific CTL in vitro to immunogenic and poorly immunogenic mouse tumors.

B Liu, E R Podack, J P Allison, T R Malek
Journal: The Journal of Immunology
J Immunol (1996) 156 (3): 1117–1125.
DOI: https://doi.org/10.4049/jimmunol.156.3.1117
Published: 01 February 1996
View article titled, Generation of primary tumor-specific CTL in vitro to immunogenic and poorly immunogenic mouse tumors.
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Journal Articles

The IL-2 receptor gamma c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor.

Y W He, T R Malek
Journal: The Journal of Immunology
J Immunol (1995) 155 (1): 9–12.
DOI: https://doi.org/10.4049/jimmunol.155.1.9
Published: 01 July 1995
View article titled, The IL-2 receptor gamma c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor.
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Journal Articles

Expression and function of the gamma c subunit of the IL-2, IL-4, and IL-7 receptors. Distinct interaction of gamma c in the IL-4 receptor.

Y W He, B Adkins, R K Furse, T R Malek
Journal: The Journal of Immunology
J Immunol (1995) 154 (4): 1596–1605.
DOI: https://doi.org/10.4049/jimmunol.154.4.1596
Published: 15 February 1995
View article titled, Expression and function of the gamma c subunit of the IL-2, IL-4, and IL-7 receptors. Distinct interaction of gamma c in the IL-4 receptor.
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Journal Articles

Formation of high affinity IL-2 receptors is dependent on a nonligand binding region of the alpha subunit.

N S Gutgsell, T R Malek
Journal: The Journal of Immunology
J Immunol (1994) 153 (9): 3899–3907.
DOI: https://doi.org/10.4049/jimmunol.153.9.3899
Published: 01 November 1994
View article titled, Formation of high affinity IL-2 receptors is dependent on a nonligand binding region of the alpha subunit.
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Journal Articles

Regulation of nuclear factor-kappa B and activator protein-1 activities after stimulation of T cells via glycosylphosphatidylinositol-anchored Ly-6A/E.

V Ivanov, T J Fleming, T R Malek
Journal: The Journal of Immunology
J Immunol (1994) 153 (6): 2394–2406.
DOI: https://doi.org/10.4049/jimmunol.153.6.2394
Published: 15 September 1994
View article titled, Regulation of nuclear factor-kappa B and activator protein-1 activities after stimulation of T cells via glycosylphosphatidylinositol-anchored Ly-6A/E.
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Journal Articles

Multiple glycosylphosphatidylinositol-anchored Ly-6 molecules and transmembrane Ly-6E mediate inhibition of IL-2 production.

T J Fleming, T R Malek
Journal: The Journal of Immunology
J Immunol (1994) 153 (5): 1955–1962.
DOI: https://doi.org/10.4049/jimmunol.153.5.1955
Published: 01 September 1994
View article titled, Multiple glycosylphosphatidylinositol-anchored Ly-6 molecules and transmembrane Ly-6E mediate inhibition of IL-2 production.
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Journal Articles

Subsets of activated CD4 T lymphocytes refractory for secretion of IL-2 are distinguished by expression of Ly-6A/E in BALB/c mice.

E K Codias, T R Malek
Journal: The Journal of Immunology
J Immunol (1993) 151 (11): 5918–5929.
DOI: https://doi.org/10.4049/jimmunol.151.11.5918
Published: 01 December 1993
View article titled, Subsets of activated CD4 T lymphocytes refractory for secretion of IL-2 are distinguished by expression of Ly-6A/E in BALB/c mice.
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Journal Articles

Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family.

T J Fleming, M L Fleming, T R Malek
Journal: The Journal of Immunology
J Immunol (1993) 151 (5): 2399–2408.
DOI: https://doi.org/10.4049/jimmunol.151.5.2399
Published: 01 September 1993
View article titled, Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family.
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Journal Articles

Characterization of two novel Ly-6 genes. Protein sequence and potential structural similarity to alpha-bungarotoxin and other neurotoxins.

T J Fleming, C O'hUigin, T R Malek
Journal: The Journal of Immunology
J Immunol (1993) 150 (12): 5379–5390.
DOI: https://doi.org/10.4049/jimmunol.150.12.5379
Published: 15 June 1993
View article titled, Characterization of two novel Ly-6 genes. Protein sequence and potential structural similarity to alpha-bungarotoxin and other neurotoxins.
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Journal Articles

Role of Ly-6A/E and T cell receptor-zeta for IL-2 production. Phosphatidylinositol-anchored Ly-6A/E antagonizes T cell receptor-mediated IL-2 production by a zeta-independent pathway.

E K Codias, T J Fleming, C M Zacharchuk, J D Ashwell, T R Malek
Journal: The Journal of Immunology
J Immunol (1992) 149 (6): 1825–1852.
DOI: https://doi.org/10.4049/jimmunol.149.6.1825
Published: 15 September 1992
View article titled, Role of Ly-6A/E and T cell receptor-zeta for IL-2 production. Phosphatidylinositol-anchored Ly-6A/E antagonizes T cell receptor-mediated IL-2 production by a zeta-independent pathway.
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Journal Articles

Down-regulation of IL-2 production by activation of T cells through Ly-6A/E.

E K Codias, J E Rutter, T J Fleming, T R Malek
Journal: The Journal of Immunology
J Immunol (1990) 145 (5): 1407–1414.
DOI: https://doi.org/10.4049/jimmunol.145.5.1407
Published: 01 September 1990
View article titled, Down-regulation of IL-2 production by activation of T cells through Ly-6A/E.
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Journal Articles

Regulation of B lymphocyte responses to IL-4 and IFN-gamma by activation through Ly-6A/E molecules.

E K Codias, T R Malek
Journal: The Journal of Immunology
J Immunol (1990) 144 (6): 2197–2204.
DOI: https://doi.org/10.4049/jimmunol.144.6.2197
Published: 15 March 1990
View article titled, Regulation of B lymphocyte responses to IL-4 and IFN-gamma by activation through Ly-6A/E molecules.
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Journal Articles

Activation of T lymphocytes through the Ly-6 pathway is defective in A strain mice.

T R Malek, E M Shevach, K M Danis
Journal: The Journal of Immunology
J Immunol (1989) 143 (2): 439–445.
DOI: https://doi.org/10.4049/jimmunol.143.2.439
Published: 15 July 1989
View article titled, Activation of T lymphocytes through the Ly-6 pathway is defective in A strain mice.
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Journal Articles

Tumor necrosis factor synergistically acts with IFN-gamma to regulate Ly-6A/E expression in T lymphocytes, thymocytes and bone marrow cells.

T R Malek, K M Danis, E K Codias
Journal: The Journal of Immunology
J Immunol (1989) 142 (6): 1929–1936.
DOI: https://doi.org/10.4049/jimmunol.142.6.1929
Published: 15 March 1989
View article titled, Tumor necrosis factor synergistically acts with IFN-gamma to regulate Ly-6A/E expression in T lymphocytes, thymocytes and bone marrow cells.
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Journal Articles

Direct identification of the murine IL-2 receptor p55-p75 heterodimer in the absence of IL-2.

H Saragovi, T R Malek
Journal: The Journal of Immunology
J Immunol (1988) 141 (2): 476–482.
DOI: https://doi.org/10.4049/jimmunol.141.2.476
Published: 15 July 1988
View article titled, Direct identification of the murine IL-2 receptor p55-p75 heterodimer in the absence of IL-2.
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Journal Articles

Graft-versus-host reaction-induced immune modulation. I. Donor-recipient genetic disparity and the differential expression of Lyt-2, L3T4, and Ly-6 during acute reactions in the host thymus.

R B Levy, A H Cotterell, M Jones, T R Malek
Journal: The Journal of Immunology
J Immunol (1988) 140 (6): 1717–1725.
DOI: https://doi.org/10.4049/jimmunol.140.6.1717
Published: 15 March 1988
View article titled, Graft-versus-host reaction-induced immune modulation. I. Donor-recipient genetic disparity and the differential expression of Lyt-2, L3T4, and Ly-6 during acute reactions in the host thymus.
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Journal Articles

The murine interleukin 2 receptor. Irreversible cross-linking of radiolabeled interleukin 2 to high affinity interleukin 2 receptors reveals a noncovalently associated subunit.

H Saragovi, T R Malek
Journal: The Journal of Immunology
J Immunol (1987) 139 (6): 1918–1926.
DOI: https://doi.org/10.4049/jimmunol.139.6.1918
Published: 15 September 1987
View article titled, The murine interleukin 2 receptor. Irreversible cross-linking of radiolabeled interleukin 2 to high affinity interleukin 2 receptors reveals a noncovalently associated subunit.
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Journal Articles

Role of Ly-6 in lymphocyte activation. I. Characterization of a monoclonal antibody to a nonpolymorphic Ly-6 specificity.

G Ortega, P E Korty, E M Shevach, T R Malek
Journal: The Journal of Immunology
J Immunol (1986) 137 (10): 3240–3246.
DOI: https://doi.org/10.4049/jimmunol.137.10.3240
Published: 15 November 1986
View article titled, Role of Ly-6 in lymphocyte activation. I. Characterization of a monoclonal antibody to a nonpolymorphic Ly-6 specificity.
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