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Takanori Kanai
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Journal Articles

Enrichement of type I interferon signalling in the colonic ILC2 under inflammatory condition

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Yohei Mikami, Irie Emi, Ishihara Rino, Mizushima Ichiro, Takanori Kanai
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 61.04.
https://doi.org/10.4049/jimmunol.210.Supp.61.04
Published: 01 May 2023
View articletitled, Enrichement of type I interferon signalling in the colonic ILC2 under inflammatory condition
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Journal Articles

New classification of CD4+CD8a+ double positive cells in Crohn’s disease patients

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Shun Tanemoto, Tomohisa Sujino, Yuya Hagihara, Yoshiaki Takada, Yusuke Yoshimatsu, Satoko Umeda, Ena Nomura, Keiko Ono, Yohei Mikami, Makoto Naganuma, Takanori Kanai
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 224.2.
https://doi.org/10.4049/jimmunol.204.Supp.224.2
Published: 01 May 2020
View articletitled, New classification of CD4+CD8a+ double positive cells in Crohn’s disease patients
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Journal Articles

Glycolysis gene Hif1a negatively regulates the induction of intraepithelial CD4+CD8aa+ T cells

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Tomohisa Sujino, Yosuke Harada, Ena Nomura, Kentaro Miyamoto, Shun Tanemoto, Yusuke Yoshimatsu, Yoshiaki Kubota, Takanori Kanai
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 72.2.
https://doi.org/10.4049/jimmunol.204.Supp.72.2
Published: 01 May 2020
View articletitled, Glycolysis gene Hif1a negatively regulates the induction of intraepithelial CD4+CD8aa+ T cells
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Journal Articles

The herbal medicine ‘Indigo naturalis’ altered gut microbiota to accumulate IL-22+ ILC3s

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Yusuke Yoshimatsu, Toshiaki Teratani, Tomohisa Sujino, Yohei Mikami, Masataka Ichikawa, Yuya Hagihara, Yoshiaki Takada, Shun Tanemoto, Satoko Umeda, Ena Nomura, Keiko Ono, Shinya Sugimoto, Kosaku Nanki, Makoto Naganuma, Takanori Kanai
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 83.11.
https://doi.org/10.4049/jimmunol.204.Supp.83.11
Published: 01 May 2020
View articletitled, The herbal medicine ‘Indigo naturalis’ altered gut microbiota to accumulate IL-22+ ILC3s
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Journal Articles

Intestinal barrier disruption inversely regulates liver inflammation via IL-10-producing macrophages

Free
Nobuhito Taniki, Nobuhiro Nakamoto, Yohei Mikami, Takanori Kanai
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 221.2.
https://doi.org/10.4049/jimmunol.198.Supp.221.2
Published: 01 May 2017
View articletitled, Intestinal barrier disruption inversely regulates liver inflammation via IL-10-producing macrophages
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Journal Articles

The gut-liver axis plays a crucial role in murine immune tolerance in the liver

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NOBUHIRO NAKAMOTO, Hirotoshi Ebinuma, Takeru Amiya, Ryo Aoki, Atsushi Hayashi, Nobuhito Taniki, Po-Sung Chu, Akihiro Yamaguchi, Hidetsugu Saito, Takanori Kanai
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 197.16.
https://doi.org/10.4049/jimmunol.196.Supp.197.16
Published: 01 May 2016
View articletitled, The gut-liver axis plays a crucial role in murine immune tolerance in the liver
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Journal Articles

Glycolysis regulates macrophage differentiation into IL-10 producing phenotype (INM6P.342)

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Hiroaki Suzuki, Tadakazu Hisamatsu, Makoto Naganuma, Hirotoshi Ebinuma, Nobuhiro Nakamoto, Kiyoto Mori, Mina Kitazume, Katsuyoshi Shimamura, Sayako Chiba, Takanori Kanai
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 193.16.
https://doi.org/10.4049/jimmunol.194.Supp.193.16
Published: 01 May 2015
View articletitled, Glycolysis regulates macrophage differentiation into IL-10 producing phenotype (INM6P.342)
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Journal Articles

Th1/Th17-Mediated Interstitial Pneumonia in Chronic Colitis Mice Independent of Intestinal Microbiota

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Yasuhiro Nemoto, Takanori Kanai, Masahiro Takahara, Shigeru Oshima, Ryuichi Okamoto, Kiichiro Tsuchiya, Satoshi Matsumoto, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2013) 190 (12): 6616–6625.
https://doi.org/10.4049/jimmunol.1202930
Published: 15 June 2013
View articletitled, Th1/Th17-Mediated Interstitial Pneumonia in Chronic Colitis Mice Independent of Intestinal Microbiota
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Includes: Supplementary data
Journal Articles

The Development of Colitogenic CD4+ T Cells Is Regulated by IL-7 in Collaboration with NK Cell Function in a Murine Model of Colitis

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Osamu Yamaji, Takashi Nagaishi, Teruji Totsuka, Michio Onizawa, Masahiro Suzuki, Naoto Tsuge, Atsuhiko Hasegawa, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Hisashi Arase, Takanori Kanai, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2012) 188 (6): 2524–2536.
https://doi.org/10.4049/jimmunol.1100371
Published: 15 March 2012
View articletitled, The Development of Colitogenic CD4+ T Cells Is Regulated by IL-7 in Collaboration with NK Cell Function in a Murine Model of Colitis
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Includes: Supplementary data
Journal Articles

Upregulated IL-7 Receptor α Expression on Colitogenic Memory CD4+ T Cells May Participate in the Development and Persistence of Chronic Colitis

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Tamako Shinohara, Yasuhiro Nemoto, Takanori Kanai, Kaori Kameyama, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Teruji Totsuka, Koichi Ikuta, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2011) 186 (4): 2623–2632.
https://doi.org/10.4049/jimmunol.1000057
Published: 15 February 2011
View articletitled, Upregulated IL-7 Receptor α Expression on Colitogenic Memory CD4+ T Cells May Participate in the Development and Persistence of Chronic Colitis
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Includes: Supplementary data
Journal Articles

Monocyte Chemoattractant Protein-1 Contributes to Gut Homeostasis and Intestinal Inflammation by Composition of IL-10–Producing Regulatory Macrophage Subset

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Yasuhiro Takada, Tadakazu Hisamatsu, Nobuhiko Kamada, Mina T. Kitazume, Haruki Honda, Yosuke Oshima, Riko Saito, Tetsuro Takayama, Taku Kobayashi, Hiroshi Chinen, Yohei Mikami, Takanori Kanai, Susumu Okamoto, Toshifumi Hibi
Journal: The Journal of Immunology
J Immunol (2010) 184 (5): 2671–2676.
https://doi.org/10.4049/jimmunol.0804012
Published: 01 March 2010
View articletitled, Monocyte Chemoattractant Protein-1 Contributes to Gut Homeostasis and Intestinal Inflammation by Composition of IL-10–Producing Regulatory Macrophage Subset
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Journal Articles

Long-Lived Colitogenic CD4+ Memory T Cells Residing Outside the Intestine Participate in the Perpetuation of Chronic Colitis

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Yasuhiro Nemoto, Takanori Kanai, Kaori Kameyama, Tamako Shinohara, Naoya Sakamoto, Teruji Totsuka, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Tetsuo Sudo, Satoshi Matsumoto, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2009) 183 (8): 5059–5068.
https://doi.org/10.4049/jimmunol.0803684
Published: 15 October 2009
View articletitled, Long-Lived Colitogenic CD4+ Memory T Cells Residing Outside the Intestine Participate in the Perpetuation of Chronic Colitis
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Journal Articles

Human CD14+ Macrophages in Intestinal Lamina Propria Exhibit Potent Antigen-Presenting Ability

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Nobuhiko Kamada, Tadakazu Hisamatsu, Haruki Honda, Taku Kobayashi, Hiroshi Chinen, Mina Tokutake Kitazume, Tetsuro Takayama, Susumu Okamoto, Kazutaka Koganei, Akira Sugita, Takanori Kanai, Toshifumi Hibi
Journal: The Journal of Immunology
J Immunol (2009) 183 (3): 1724–1731.
https://doi.org/10.4049/jimmunol.0804369
Published: 01 August 2009
View articletitled, Human CD14+ Macrophages in Intestinal Lamina Propria Exhibit Potent Antigen-Presenting Ability
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Journal Articles

RANK-RANKL Signaling Pathway Is Critically Involved in the Function of CD4+CD25+ Regulatory T Cells in Chronic Colitis

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Teruji Totsuka, Takanori Kanai, Yasuhiro Nemoto, Takayuki Tomita, Ryuichi Okamoto, Kiichiro Tsuchiya, Tetsuya Nakamura, Naoya Sakamoto, Hisaya Akiba, Ko Okumura, Hideo Yagita, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2009) 182 (10): 6079–6087.
https://doi.org/10.4049/jimmunol.0711823
Published: 15 May 2009
View articletitled, RANK-RANKL Signaling Pathway Is Critically Involved in the Function of CD4+CD25+ Regulatory T Cells in Chronic Colitis
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Journal Articles

MyD88-Dependent Pathway in T Cells Directly Modulates the Expansion of Colitogenic CD4+ T Cells in Chronic Colitis

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Takayuki Tomita, Takanori Kanai, Toshimitsu Fujii, Yasuhiro Nemoto, Ryuichi Okamoto, Kiichiro Tsuchiya, Teruji Totsuka, Naoya Sakamoto, Shizuo Akira, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2008) 180 (8): 5291–5299.
https://doi.org/10.4049/jimmunol.180.8.5291
Published: 15 April 2008
View articletitled, MyD88-Dependent Pathway in T Cells Directly Modulates the Expansion of Colitogenic CD4+ T Cells in Chronic Colitis
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Journal Articles

Systemic, but Not Intestinal, IL-7 Is Essential for the Persistence of Chronic Colitis

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Takayuki Tomita, Takanori Kanai, Yasuhiro Nemoto, Teruji Totsuka, Ryuichi Okamoto, Kiichiro Tsuchiya, Naoya Sakamoto, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2008) 180 (1): 383–390.
https://doi.org/10.4049/jimmunol.180.1.383
Published: 01 January 2008
View articletitled, Systemic, but Not Intestinal, IL-7 Is Essential for the Persistence of Chronic Colitis
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Journal Articles

IL-7 Is Essential for the Development and the Persistence of Chronic Colitis

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Teruji Totsuka, Takanori Kanai, Yasuhiro Nemoto, Shin Makita, Ryuichi Okamoto, Kiichiro Tsuchiya, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2007) 178 (8): 4737–4748.
https://doi.org/10.4049/jimmunol.178.8.4737
Published: 15 April 2007
View articletitled, IL-7 Is Essential for the Development and the Persistence of Chronic Colitis
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Journal Articles

Intestinal Lamina Propria Retaining CD4+CD25+ Regulatory T Cells Is A Suppressive Site of Intestinal Inflammation

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Shin Makita, Takanori Kanai, Yasuhiro Nemoto, Teruji Totsuka, Ryuichi Okamoto, Kiichiro Tsuchiya, Masafumi Yamamoto, Hiroshi Kiyono, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2007) 178 (8): 4937–4946.
https://doi.org/10.4049/jimmunol.178.8.4937
Published: 15 April 2007
View articletitled, Intestinal Lamina Propria Retaining CD4+CD25+ Regulatory T Cells Is A Suppressive Site of Intestinal Inflammation
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Journal Articles

CD4+CD25bright T Cells in Human Intestinal Lamina Propria as Regulatory Cells

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Shin Makita, Takanori Kanai, Shigeru Oshima, Koji Uraushihara, Teruji Totsuka, Taisuke Sawada, Tetsuya Nakamura, Kazutaka Koganei, Tsuneo Fukushima, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2004) 173 (5): 3119–3130.
https://doi.org/10.4049/jimmunol.173.5.3119
Published: 01 September 2004
View articletitled, CD4+CD25bright T Cells in Human Intestinal Lamina Propria as Regulatory Cells
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Journal Articles

Ectopic CD40 Ligand Expression on B Cells Triggers Intestinal Inflammation

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Takahiro Kawamura, Takanori Kanai, Taeko Dohi, Koji Uraushihara, Teruji Totsuka, Ryoichi Iiyama, Chikara Taneda, Motomi Yamazaki, Tetsuya Nakamura, Tetsuya Higuchi, Yuichi Aiba, Takeshi Tsubata, Mamoru Watanabe
Journal: The Journal of Immunology
J Immunol (2004) 172 (10): 6388–6397.
https://doi.org/10.4049/jimmunol.172.10.6388
Published: 15 May 2004
View articletitled, Ectopic CD40 Ligand Expression on B Cells Triggers Intestinal Inflammation
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