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Thomas C. Pearson
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Journal Articles

Pillars Article: Long-Term Acceptance of Skin and Cardiac Allografts after Blocking CD40 and CD28 Pathways. Nature. 1996. 381: 434–438

Christian P. Larsen, Eric T. Elwood, Diane Z. Alexander, Shannon C. Ritchie, Rose Hendrix, Carol Tucker-Burden, Hong Rae Cho, Alejandro Aruffo, Diane Hollenbaugh, Peter S. Linsley, Kevin J. Winn, Thomas C. Pearson
Journal: The Journal of Immunology
J Immunol (2011) 186 (5): 2693–2697.
Published: 01 March 2011
View article titled, Pillars Article: Long-Term Acceptance of Skin and Cardiac Allografts after Blocking CD40 and CD28 Pathways. <em>Nature</em>. 1996. 381: 434–438
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Anti-CD40 Monoclonal Antibody Synergizes with CTLA4-Ig in Promoting Long-Term Graft Survival in Murine Models of Transplantation

Christopher R. Gilson, Zvonimir Milas, Shivaprakash Gangappa, Diane Hollenbaugh, Thomas C. Pearson, Mandy L. Ford, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2009) 183 (3): 1625–1635.
https://doi.org/10.4049/jimmunol.0900339
Published: 01 August 2009
View article titled, Anti-CD40 Monoclonal Antibody Synergizes with CTLA4-Ig in Promoting Long-Term Graft Survival in Murine Models of Transplantation
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A Critical Precursor Frequency of Donor-Reactive CD4+ T Cell Help Is Required for CD8+ T Cell-Mediated CD28/CD154-Independent Rejection

Mandy L. Ford, Maylene E. Wagener, Samantha S. Hanna, Thomas C. Pearson, Allan D. Kirk, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2008) 180 (11): 7203–7211.
https://doi.org/10.4049/jimmunol.180.11.7203
Published: 01 June 2008
View article titled, A Critical Precursor Frequency of Donor-Reactive CD4<sup>+</sup> T Cell Help Is Required for CD8<sup>+</sup> T Cell-Mediated CD28/CD154-Independent Rejection
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Journal Articles

Fully MHC-Disparate Mixed Hemopoietic Chimeras Show Specific Defects in the Control of Chronic Viral Infections

Brent H. Koehn, Matthew A. Williams, Keshawna Borom, Shivaprakash Gangappa, Thomas C. Pearson, Rafi Ahmed, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2007) 179 (4): 2616–2626.
https://doi.org/10.4049/jimmunol.179.4.2616
Published: 15 August 2007
View article titled, Fully MHC-Disparate Mixed Hemopoietic Chimeras Show Specific Defects in the Control of Chronic Viral Infections
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Journal Articles

Costimulation Requirements for Antiviral CD8+ T Cells Differ for Acute and Persistent Phases of Polyoma Virus Infection

Christopher C. Kemball, Eun D. Han Lee, Eva Szomolanyi-Tsuda, Thomas C. Pearson, Christian P. Larsen, Aron E. Lukacher
Journal: The Journal of Immunology
J Immunol (2006) 176 (3): 1814–1824.
https://doi.org/10.4049/jimmunol.176.3.1814
Published: 01 February 2006
View article titled, Costimulation Requirements for Antiviral CD8<sup>+</sup> T Cells Differ for Acute and Persistent Phases of Polyoma Virus Infection
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Journal Articles

Late Priming and Variability of Epitope-Specific CD8+ T Cell Responses during a Persistent Virus Infection

Christopher C. Kemball, Eun D. Han Lee, Vaiva Vezys, Thomas C. Pearson, Christian P. Larsen, Aron E. Lukacher
Journal: The Journal of Immunology
J Immunol (2005) 174 (12): 7950–7960.
https://doi.org/10.4049/jimmunol.174.12.7950
Published: 15 June 2005
View article titled, Late Priming and Variability of Epitope-Specific CD8<sup>+</sup> T Cell Responses during a Persistent Virus Infection
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Development of a Chimeric Anti-CD40 Monoclonal Antibody That Synergizes with LEA29Y to Prolong Islet Allograft Survival

Andrew B. Adams, Nozomu Shirasugi, Thomas R. Jones, Megan M. Durham, Elizabeth A. Strobert, Shannon Cowan, Phyllis Rees, Rose Hendrix, Karen Price, Norma S. Kenyon, David Hagerty, Robert Townsend, Dianne Hollenbaugh, Thomas C. Pearson, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2005) 174 (1): 542–550.
https://doi.org/10.4049/jimmunol.174.1.542
Published: 01 January 2005
View article titled, Development of a Chimeric Anti-CD40 Monoclonal Antibody That Synergizes with LEA29Y to Prolong Islet Allograft Survival
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Journal Articles

Primary and Secondary Immunocompetence in Mixed Allogeneic Chimeras

Matthew A. Williams, Andrew B. Adams, Melody B. Walsh, Nozomu Shirasugi, Thandi M. Onami, Thomas C. Pearson, Rafi Ahmed, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2003) 170 (5): 2382–2389.
https://doi.org/10.4049/jimmunol.170.5.2382
Published: 01 March 2003
View article titled, Primary and Secondary Immunocompetence in Mixed Allogeneic Chimeras
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Journal Articles

Cutting Edge: Persistent Viral Infection Prevents Tolerance Induction and Escapes Immune Control Following CD28/CD40 Blockade-Based Regimen

Matthew A. Williams, Thandi M. Onami, Andrew B. Adams, Megan M. Durham, Thomas C. Pearson, Rafi Ahmed, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2002) 169 (10): 5387–5391.
https://doi.org/10.4049/jimmunol.169.10.5387
Published: 15 November 2002
View article titled, Cutting Edge: Persistent Viral Infection Prevents Tolerance Induction and Escapes Immune Control Following CD28/CD40 Blockade-Based Regimen
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Journal Articles

Prevention of Chronic Rejection in Murine Cardiac Allografts: A Comparison of Chimerism- and Nonchimerism-Inducing Costimulation Blockade-Based Tolerance Induction Regimens

Nozomu Shirasugi, Andrew B. Adams, Megan M. Durham, Aron E. Lukacher, Huaying Xu, Phyllis Rees, Shannon R. Cowan, Matthew A. Williams, Thomas C. Pearson, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2002) 169 (5): 2677–2684.
https://doi.org/10.4049/jimmunol.169.5.2677
Published: 01 September 2002
View article titled, Prevention of Chronic Rejection in Murine Cardiac Allografts: A Comparison of Chimerism- and Nonchimerism-Inducing Costimulation Blockade-Based Tolerance Induction Regimens
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Journal Articles

Dynamic Regulation of T Cell Immunity by CD43

Thandi M. Onami, Laurie E. Harrington, Matthew A. Williams, Marisa Galvan, Christian P. Larsen, Thomas C. Pearson, N. Manjunath, Linda G. Baum, Brad D. Pearce, Rafi Ahmed
Journal: The Journal of Immunology
J Immunol (2002) 168 (12): 6022–6031.
https://doi.org/10.4049/jimmunol.168.12.6022
Published: 15 June 2002
View article titled, Dynamic Regulation of T Cell Immunity by CD43
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Journal Articles

The Role of the IL-2 Pathway in Costimulation Blockade-Resistant Rejection of Allografts

Thomas R. Jones, Jongwon Ha, Matthew A. Williams, Andrew B. Adams, Megan M. Durham, Phyllis A. Rees, Shannon R. Cowan, Thomas C. Pearson, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2002) 168 (3): 1123–1130.
https://doi.org/10.4049/jimmunol.168.3.1123
Published: 01 February 2002
View article titled, The Role of the IL-2 Pathway in Costimulation Blockade-Resistant Rejection of Allografts
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Journal Articles

Role of CD28-B7 Interactions in Generation and Maintenance of CD8 T Cell Memory

M. Suresh, Jason K. Whitmire, Laurie E. Harrington, Christian P. Larsen, Thomas C. Pearson, John D. Altman, Rafi Ahmed
Journal: The Journal of Immunology
J Immunol (2001) 167 (10): 5565–5573.
https://doi.org/10.4049/jimmunol.167.10.5565
Published: 15 November 2001
View article titled, Role of CD28-B7 Interactions in Generation and Maintenance of CD8 T Cell Memory
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Journal Articles

Characterization of Virus-Mediated Inhibition of Mixed Chimerism and Allospecific Tolerance

Matthew A. Williams, Joyce T. Tan, Andrew B. Adams, Megan M. Durham, Nozomu Shirasugi, Jason K. Whitmire, Laurie E. Harrington, Rafi Ahmed, Thomas C. Pearson, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2001) 167 (9): 4987–4995.
https://doi.org/10.4049/jimmunol.167.9.4987
Published: 01 November 2001
View article titled, Characterization of Virus-Mediated Inhibition of Mixed Chimerism and Allospecific Tolerance
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Journal Articles

Costimulation Blockade, Busulfan, and Bone Marrow Promote Titratable Macrochimerism, Induce Transplantation Tolerance, and Correct Genetic Hemoglobinopathies with Minimal Myelosuppression

Andrew B. Adams, Megan M. Durham, Leslie Kean, Nozomu Shirasugi, Jongwon Ha, Matthew A. Williams, Phyllis A. Rees, Michael C. Cheung, Stephen Mittelstaedt, Adam W. Bingaman, David R. Archer, Thomas C. Pearson, Edmund K. Waller, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2001) 167 (2): 1103–1111.
https://doi.org/10.4049/jimmunol.167.2.1103
Published: 15 July 2001
View article titled, Costimulation Blockade, Busulfan, and Bone Marrow Promote Titratable Macrochimerism, Induce Transplantation Tolerance, and Correct Genetic Hemoglobinopathies with Minimal Myelosuppression
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Genetic Characterization of Strain Differences in the Ability to Mediate CD40/CD28-Independent Rejection of Skin Allografts

Matthew A. Williams, Joel Trambley, Jongwon Ha, Andrew B. Adams, Megan M. Durham, Phyllis Rees, Shannon R. Cowan, Thomas C. Pearson, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2000) 165 (12): 6849–6857.
https://doi.org/10.4049/jimmunol.165.12.6849
Published: 15 December 2000
View article titled, Genetic Characterization of Strain Differences in the Ability to Mediate CD40/CD28-Independent Rejection of Skin Allografts
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Journal Articles

Cutting Edge: Administration of Anti-CD40 Ligand and Donor Bone Marrow Leads to Hemopoietic Chimerism and Donor-Specific Tolerance Without Cytoreductive Conditioning

Megan M. Durham, Adam W. Bingaman, Andrew B. Adams, Jongwon Ha, Seung-Yeun Waitze, Thomas C. Pearson, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2000) 165 (1): 1–4.
https://doi.org/10.4049/jimmunol.165.1.1
Published: 01 July 2000
View article titled, Cutting Edge: Administration of Anti-CD40 Ligand and Donor Bone Marrow Leads to Hemopoietic Chimerism and Donor-Specific Tolerance Without Cytoreductive Conditioning
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Vigorous Allograft Rejection in the Absence of Danger

Adam W. Bingaman, Jongwon Ha, Seung-Yeun Waitze, Megan M. Durham, Hong Rae Cho, Carol Tucker-Burden, Rose Hendrix, Shannon R. Cowan, Thomas C. Pearson, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2000) 164 (6): 3065–3071.
https://doi.org/10.4049/jimmunol.164.6.3065
Published: 15 March 2000
View article titled, Vigorous Allograft Rejection in the Absence of Danger
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4-1BB Costimulation Is Required for Protective Anti-Viral Immunity After Peptide Vaccination

Joyce T. Tan, Jason K. Whitmire, Kaja Murali-Krishna, Rafi Ahmed, John D. Altman, Robert S. Mittler, Alessandro Sette, Thomas C. Pearson, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (2000) 164 (5): 2320–2325.
https://doi.org/10.4049/jimmunol.164.5.2320
Published: 01 March 2000
View article titled, 4-1BB Costimulation Is Required for Protective Anti-Viral Immunity After Peptide Vaccination
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4-1BB Ligand, a Member of the TNF Family, Is Important for the Generation of Antiviral CD8 T Cell Responses

Joyce T. Tan, Jason K. Whitmire, Rafi Ahmed, Thomas C. Pearson, Christian P. Larsen
Journal: The Journal of Immunology
J Immunol (1999) 163 (9): 4859–4868.
https://doi.org/10.4049/jimmunol.163.9.4859
Published: 01 November 1999
View article titled, 4-1BB Ligand, a Member of the TNF Family, Is Important for the Generation of Antiviral CD8 T Cell Responses
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