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Todd M. Brusko
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Journal Articles

NADPH Oxidase 2–Derived Reactive Oxygen Species Promote CD8+ T Cell Effector Function

Jing Chen, Chao Liu, Anna V. Chernatynskaya, Brittney Newby, Todd M. Brusko, Yuan Xu, Jessie M. Barra, Nadine Morgan, Christopher Santarlas, Westley H. Reeves, Hubert M. Tse, Jennifer W. Leiding, Clayton E. Mathews
Journal: The Journal of Immunology
J Immunol (2024) 212 (2): 258–270.
https://doi.org/10.4049/jimmunol.2200691
Published: 11 December 2023
View articletitled, NADPH Oxidase 2–Derived Reactive Oxygen Species Promote CD8+ T Cell Effector Function
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Includes: Supplementary data
Journal Articles

Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells

Melanie R. Shapiro, Leeana D. Peters, Matthew E. Brown, Cecilia Cabello-Kindelan, Amanda L. Posgai, Allison L. Bayer, Todd M. Brusko
Journal: The Journal of Immunology
J Immunol (2023) 211 (7): 1108–1122.
https://doi.org/10.4049/jimmunol.2200651
Published: 18 August 2023
View articletitled, Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells
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Includes: Supplementary data
Journal Articles

Overexpression of the PTPN22 Autoimmune Risk Variant LYP-620W Fails to Restrain Human CD4+ T Cell Activation

Daniel J. Perry, Leeana D. Peters, Priya Saikumar Lakshmi, Lin Zhang, Zhao Han, Clive H. Wasserfall, Clayton E. Mathews, Mark A. Atkinson, Todd M. Brusko
Journal: The Journal of Immunology
J Immunol (2021) 207 (3): 849–859.
https://doi.org/10.4049/jimmunol.2000708
Published: 01 August 2021
View articletitled, Overexpression of the PTPN22 Autoimmune Risk Variant LYP-620W Fails to Restrain Human CD4+ T Cell Activation
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Includes: Supplementary data
Journal Articles

CD70 Inversely Regulates Regulatory T Cells and Invariant NKT Cells and Modulates Type 1 Diabetes in NOD Mice

Cheng Ye, Benjamin E. Low, Michael V. Wiles, Todd M. Brusko, David V. Serreze, John P. Driver
Journal: The Journal of Immunology
J Immunol (2020) 205 (7): 1763–1777.
https://doi.org/10.4049/jimmunol.2000148
Published: 01 October 2020
View articletitled, CD70 Inversely Regulates Regulatory T Cells and Invariant NKT Cells and Modulates Type 1 Diabetes in NOD Mice
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Includes: Supplementary data
Journal Articles

Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes–Associated HLA Class II Molecules

Emmi-Leena Ihantola, Henna Ilmonen, Anssi Kailaanmäki, Marja Rytkönen-Nissinen, Aurélien Azam, Bernard Maillère, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Keshav Motwani, Howard R. Seay, Todd M. Brusko, Mikael Knip, Riitta Veijola, Jorma Toppari, Jorma Ilonen, Tuure Kinnunen
Journal: The Journal of Immunology
J Immunol (2020) 204 (9): 2349–2359.
https://doi.org/10.4049/jimmunol.1901079
Published: 01 May 2020
View articletitled, Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes–Associated HLA Class II Molecules
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Includes: Supplementary data
Journal Articles

Metformin Inhibits the Type 1 IFN Response in Human CD4+ T Cells

Anton A. Titov, Henry V. Baker, Todd M. Brusko, Eric S. Sobel, Laurence Morel
Journal: The Journal of Immunology
J Immunol (2019) 203 (2): 338–348.
https://doi.org/10.4049/jimmunol.1801651
Published: 15 July 2019
View articletitled, Metformin Inhibits the Type 1 IFN Response in Human CD4+ T Cells
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Includes: Supplementary data
Journal Articles

Metformin attenuates the Type I Interferon response in human peripheral blood leukocytes.

Anton A Titov, Todd M. Brusko, Eric Sobel, Laurence Morel
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 224.22.
https://doi.org/10.4049/jimmunol.198.Supp.224.22
Published: 01 May 2017
View articletitled, Metformin attenuates the Type I Interferon response in human peripheral blood leukocytes.
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Journal Articles

The Lupus Susceptibility Gene Pbx1 Regulates the Balance between Follicular Helper T Cell and Regulatory T Cell Differentiation

Seung-Chul Choi, Tarun E. Hutchinson, Anton A. Titov, Howard R. Seay, Shiwu Li, Todd M. Brusko, Byron P. Croker, Shahram Salek-Ardakani, Laurence Morel
Journal: The Journal of Immunology
J Immunol (2016) 197 (2): 458–469.
https://doi.org/10.4049/jimmunol.1502283
Published: 15 July 2016
View articletitled, The Lupus Susceptibility Gene Pbx1 Regulates the Balance between Follicular Helper T Cell and Regulatory T Cell Differentiation
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Includes: Supplementary data
Journal Articles

MDM2 ubiquitin ligase in Lupus CD4 T-Cell pathology.

Anton A Titov, Todd M. Brusko, Henry V Baker, Eric Sobel, Laurence Morel
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 58.9.
https://doi.org/10.4049/jimmunol.196.Supp.58.9
Published: 01 May 2016
View articletitled, MDM2 ubiquitin ligase in Lupus CD4 T-Cell pathology.
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Journal Articles

Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226

Christopher A. Fuhrman, Wen-I Yeh, Howard R. Seay, Priya Saikumar Lakshmi, Gaurav Chopra, Lin Zhang, Daniel J. Perry, Stephanie A. McClymont, Mahesh Yadav, Maria-Cecilia Lopez, Henry V. Baker, Ying Zhang, Yizheng Li, Maryann Whitley, David von Schack, Mark A. Atkinson, Jeffrey A. Bluestone, Todd M. Brusko
Journal: The Journal of Immunology
J Immunol (2015) 195 (1): 145–155.
https://doi.org/10.4049/jimmunol.1402381
Published: 01 July 2015
View articletitled, Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226
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Includes: Supplementary data
Journal Articles

Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes

Stephanie A. McClymont, Amy L. Putnam, Michael R. Lee, Jonathan H. Esensten, Weihong Liu, Maigan A. Hulme, Ulrich Hoffmüller, Udo Baron, Sven Olek, Jeffrey A. Bluestone, Todd M. Brusko
Journal: The Journal of Immunology
J Immunol (2011) 186 (7): 3918–3926.
https://doi.org/10.4049/jimmunol.1003099
Published: 01 April 2011
View articletitled, Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes
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Includes: Supplementary data
Journal Articles

An Integral Role for Heme Oxygenase-1 and Carbon Monoxide in Maintaining Peripheral Tolerance by CD4+CD25+ Regulatory T Cells

In Special Collection:
Brief Reviews
Todd M. Brusko, Clive H. Wasserfall, Anupam Agarwal, Matthias H. Kapturczak, Mark A. Atkinson
Journal: The Journal of Immunology
J Immunol (2005) 174 (9): 5181–5186.
https://doi.org/10.4049/jimmunol.174.9.5181
Published: 01 May 2005
View articletitled, An Integral Role for Heme Oxygenase-1 and Carbon Monoxide in Maintaining Peripheral Tolerance by CD4+CD25+ Regulatory T Cells
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