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A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects

Annett Ziegler, Claudia Soldner, Stefan Lienenklaus, Julia Spanier, Stephanie Trittel, Peggy Riese, Thomas Kramps, Siegfried Weiss, Regina Heidenreich, Edith Jasny, Carlos A. Guzmán, Karl-Josef Kallen, Mariola Fotin-Mleczek, Ulrich Kalinke

J Immunol (2017) 198 (4): 1595–1605.

DOI: https://doi.org/10.4049/jimmunol.1601129

Published: 15 February 2017

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Concomitant TLR/RLH Signaling of Radioresistant and Radiosensitive Cells Is Essential for Protection against Vesicular Stomatitis Virus Infection

Julia Spanier, Stefan Lienenklaus, Jennifer Paijo, Annett Kessler, Katharina Borst, Sabrina Heindorf, Darren P. Baker, Andrea Kröger, Siegfried Weiss, Claudia N. Detje, Peter Staeheli, Ulrich Kalinke

J Immunol (2014) 193 (6): 3045–3054.

DOI: https://doi.org/10.4049/jimmunol.1400959

Published: 15 September 2014

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Includes: Supplementary data

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Independent of Plasmacytoid Dendritic Cell (pDC) infection, pDC Triggered by Virus-Infected Cells Mount Enhanced Type I IFN Responses of Different Composition as Opposed to pDC Stimulated with Free Virus

Theresa Frenz, Lukas Graalmann, Claudia N. Detje, Marius Döring, Elena Grabski, Stefanie Scheu, Ulrich Kalinke

J Immunol (2014) 193 (5): 2496–2503.

DOI: https://doi.org/10.4049/jimmunol.1400215

Published: 01 September 2014

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Includes: Supplementary data

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Cell Contact–Dependent Priming and Fc Interaction with CD32⁺ Immune Cells Contribute to the TGN1412-Triggered Cytokine Response

Patrick Bartholomaeus, Linda Y. Semmler, Thomas Bukur, Valesca Boisguerin, Paula S. Römer, Paula Tabares, Sergey Chuvpilo, Dmitry Y. Tyrsin, Alexey Matskevich, Hartmut Hengel, John Castle, Thomas Hünig, Ulrich Kalinke

J Immunol (2014) 192 (5): 2091–2098.

DOI: https://doi.org/10.4049/jimmunol.1302461

Published: 01 March 2014

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Includes: Supplementary data

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Nanoparticle Adjuvant Sensing by TLR7 Enhances CD8⁺ T Cell–Mediated Protection from Listeria Monocytogenes Infection

Marie-Ève Lebel, Jean-François Daudelin, Karine Chartrand, Esther Tarrab, Ulrich Kalinke, Pierre Savard, Nathalie Labrecque, Denis Leclerc, Alain Lamarre

J Immunol (2014) 192 (3): 1071–1078.

DOI: https://doi.org/10.4049/jimmunol.1302030

Published: 01 February 2014

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Includes: Supplementary data

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IFIT2 Is an Effector Protein of Type I IFN–Mediated Amplification of Lipopolysaccharide (LPS)-Induced TNF-α Secretion and LPS-Induced Endotoxin Shock

Alexandra Siegfried, Susanne Berchtold, Birgit Manncke, Eva Deuschle, Julia Reber, Thomas Ott, Michaela Weber, Ulrich Kalinke, Markus J. Hofer, Bastian Hatesuer, Klaus Schughart, Valérie Gailus-Durner, Helmut Fuchs, Martin Hrabě de Angelis, Friedemann Weber, Mathias W. Hornef, Ingo B. Autenrieth, Erwin Bohn

J Immunol (2013) 191 (7): 3913–3921.

DOI: https://doi.org/10.4049/jimmunol.1203305

Published: 01 October 2013

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Includes: Supplementary data

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Dendritic Cells Require STAT-1 Phosphorylated at Its Transactivating Domain for the Induction of Peptide-Specific CTL

Andreas Pilz, Wolfgang Kratky, Silvia Stockinger, Olivia Simma, Ulrich Kalinke, Karen Lingnau, Alexander von Gabain, Dagmar Stoiber, Veronika Sexl, Thomas Kolbe, Thomas Rülicke, Mathias Müller, Thomas Decker

J Immunol (2009) 183 (4): 2286–2293.

DOI: https://doi.org/10.4049/jimmunol.0901383

Published: 15 August 2009

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Vaccination with Aβ-Displaying Virus-Like Particles Reduces Soluble and Insoluble Cerebral Aβ and Lowers Plaque Burden in APP Transgenic Mice

Patricia Bach, Jakob-A. Tschäpe, Ferdinand Kopietz, Gundula Braun, Janina K. Baade, Karl-Heinz Wiederhold, Matthias Staufenbiel, Marco Prinz, Thomas Deller, Ulrich Kalinke, Christian J. Buchholz, Ulrike C. Müller

J Immunol (2009) 182 (12): 7613–7624.

DOI: https://doi.org/10.4049/jimmunol.0803366

Published: 15 June 2009

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Activation of Melanoma Differentiation-Associated Gene 5 Causes Rapid Involution of the Thymus

David Anz, Raffael Thaler, Nicolas Stephan, Zoe Waibler, Michael J. Trauscheid, Christoph Scholz, Ulrich Kalinke, Winfried Barchet, Stefan Endres, Carole Bourquin

J Immunol (2009) 182 (10): 6044–6050.

DOI: https://doi.org/10.4049/jimmunol.0803809

Published: 15 May 2009

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Ncf1 Provides a Reactive Oxygen Species-Independent Negative Feedback Regulation of TLR9-Induced IL-12p70 in Murine Dendritic Cells

Cornelia Richter, Martina Herrero San Juan, Jutta Will, Ralf P. Brandes, Ulrich Kalinke, Shizuo Akira, Josef M. Pfeilschifter, Malin Hultqvist, Rikard Holmdahl, Heinfried H. Radeke

J Immunol (2009) 182 (7): 4183–4191.

DOI: https://doi.org/10.4049/jimmunol.0800795

Published: 01 April 2009

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Local Type I IFN Receptor Signaling Protects against Virus Spread within the Central Nervous System

Claudia N. Detje, Thomas Meyer, Hauke Schmidt, Dorothea Kreuz, John K. Rose, Ingo Bechmann, Marco Prinz, Ulrich Kalinke

J Immunol (2009) 182 (4): 2297–2304.

DOI: https://doi.org/10.4049/jimmunol.0800596

Published: 15 February 2009

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Type I IFN-Mediated Protection of Macrophages and Dendritic Cells Secures Control of Murine Coronavirus Infection

Luisa Cervantes-Barragán, Ulrich Kalinke, Roland Züst, Martin König, Boris Reizis, Constantino López-Macías, Volker Thiel, Burkhard Ludewig

J Immunol (2009) 182 (2): 1099–1106.

DOI: https://doi.org/10.4049/jimmunol.182.2.1099

Published: 15 January 2009

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Vesicular Stomatitis Virus Glycoprotein Displaying Retrovirus-Like Particles Induce a Type I IFN Receptor-Dependent Switch to Neutralizing IgG Antibodies

Patricia Bach, Elisabeth Kamphuis, Bernhard Odermatt, Gerd Sutter, Christian J. Buchholz, Ulrich Kalinke

J Immunol (2007) 178 (9): 5839–5847.

DOI: https://doi.org/10.4049/jimmunol.178.9.5839

Published: 01 May 2007

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Cutting Edge: CD8 T Cells Specific for Lymphocytic Choriomeningitis Virus Require Type I IFN Receptor for Clonal Expansion

Peter Aichele, Heike Unsoeld, Marie Koschella, Oliver Schweier, Ulrich Kalinke, Smiljka Vucikuja

J Immunol (2006) 176 (8): 4525–4529.

DOI: https://doi.org/10.4049/jimmunol.176.8.4525

Published: 15 April 2006

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Direct Stimulation of T Cells by Type I IFN Enhances the CD8⁺ T Cell Response during Cross-Priming

Agnes Le Bon, Vanessa Durand, Elisabeth Kamphuis, Clare Thompson, Silvia Bulfone-Paus, Cornelia Rossmann, Ulrich Kalinke, David F. Tough

J Immunol (2006) 176 (8): 4682–4689.

DOI: https://doi.org/10.4049/jimmunol.176.8.4682

Published: 15 April 2006

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Cutting Edge: Enhancement of Antibody Responses Through Direct Stimulation of B and T Cells by Type I IFN

Agnes Le Bon, Clare Thompson, Elisabeth Kamphuis, Vanessa Durand, Cornelia Rossmann, Ulrich Kalinke, David F. Tough

J Immunol (2006) 176 (4): 2074–2078.

DOI: https://doi.org/10.4049/jimmunol.176.4.2074

Published: 15 February 2006

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Novel Functions of Tyrosine Kinase 2 in the Antiviral Defense against Murine Cytomegalovirus

Birgit Strobl, Ivan Bubic, Ute Bruns, Ralf Steinborn, Robert Lajko, Thomas Kolbe, Marina Karaghiosoff, Ulrich Kalinke, Stipan Jonjic, Mathias Müller

J Immunol (2005) 175 (6): 4000–4008.

DOI: https://doi.org/10.4049/jimmunol.175.6.4000

Published: 15 September 2005

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In Vivo Selection of Neutralization-Resistant Virus Variants But No Evidence of B Cell Tolerance in Lymphocytic Choriomeningitis Virus Carrier Mice Expressing a Transgenic Virus-Neutralizing Antibody

Peter Seiler, Beatrice M. Senn, Marie-Anne Bründler, Rolf M. Zinkernagel, Hans Hengartner, Ulrich Kalinke

J Immunol (1999) 162 (8): 4536–4541.

DOI: https://doi.org/10.4049/jimmunol.162.8.4536

Published: 15 April 1999

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NARROW

A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects

Concomitant TLR/RLH Signaling of Radioresistant and Radiosensitive Cells Is Essential for Protection against Vesicular Stomatitis Virus Infection

Independent of Plasmacytoid Dendritic Cell (pDC) infection, pDC Triggered by Virus-Infected Cells Mount Enhanced Type I IFN Responses of Different Composition as Opposed to pDC Stimulated with Free Virus

Cell Contact–Dependent Priming and Fc Interaction with CD32⁺ Immune Cells Contribute to the TGN1412-Triggered Cytokine Response

Nanoparticle Adjuvant Sensing by TLR7 Enhances CD8⁺ T Cell–Mediated Protection from Listeria Monocytogenes Infection

IFIT2 Is an Effector Protein of Type I IFN–Mediated Amplification of Lipopolysaccharide (LPS)-Induced TNF-α Secretion and LPS-Induced Endotoxin Shock

Dendritic Cells Require STAT-1 Phosphorylated at Its Transactivating Domain for the Induction of Peptide-Specific CTL

Vaccination with Aβ-Displaying Virus-Like Particles Reduces Soluble and Insoluble Cerebral Aβ and Lowers Plaque Burden in APP Transgenic Mice

Activation of Melanoma Differentiation-Associated Gene 5 Causes Rapid Involution of the Thymus

Ncf1 Provides a Reactive Oxygen Species-Independent Negative Feedback Regulation of TLR9-Induced IL-12p70 in Murine Dendritic Cells

Local Type I IFN Receptor Signaling Protects against Virus Spread within the Central Nervous System

Type I IFN-Mediated Protection of Macrophages and Dendritic Cells Secures Control of Murine Coronavirus Infection

Vesicular Stomatitis Virus Glycoprotein Displaying Retrovirus-Like Particles Induce a Type I IFN Receptor-Dependent Switch to Neutralizing IgG Antibodies

Cutting Edge: CD8 T Cells Specific for Lymphocytic Choriomeningitis Virus Require Type I IFN Receptor for Clonal Expansion

Direct Stimulation of T Cells by Type I IFN Enhances the CD8⁺ T Cell Response during Cross-Priming

Cutting Edge: Enhancement of Antibody Responses Through Direct Stimulation of B and T Cells by Type I IFN

Novel Functions of Tyrosine Kinase 2 in the Antiviral Defense against Murine Cytomegalovirus

In Vivo Selection of Neutralization-Resistant Virus Variants But No Evidence of B Cell Tolerance in Lymphocytic Choriomeningitis Virus Carrier Mice Expressing a Transgenic Virus-Neutralizing Antibody

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