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Uma Sriram
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Journal Articles

Tissue kallikrein suppresses interferon responses and reduces depressive-like behavior in lupus-prone mice.

Uma Sriram, Cassandra Nocito, Cody Lubinsky, Michelle Hand, Alecia Seliga, Yuri Persidsky
Journal: The Journal of Immunology
J Immunol (2023) 210 (1_Supplement): 238.18.
https://doi.org/10.4049/jimmunol.210.Supp.238.18
Published: 01 May 2023
View article titled, Tissue kallikrein suppresses interferon responses and reduces depressive-like behavior in lupus-prone mice.
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Journal Articles

Angiotensin-converting enzyme inhibitor suppresses Type I interferon responses, decreases neuroinflammation and improves depression-like behavior in MRL/lpr lupusprone mice

Uma Sriram, Cassandra Nocito, Michelle Hand, Cody Lubinsky, Alecia Seliga, Viviana Zuluaga-Ramirez, Malika Winfield, Yuri Persidsky
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 132.9.
https://doi.org/10.4049/jimmunol.202.Supp.132.9
Published: 01 May 2019
View article titled, Angiotensin-converting enzyme inhibitor suppresses Type I interferon responses, decreases neuroinflammation and improves depression-like behavior in MRL/lpr lupusprone mice
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Journal Articles

Kallikrein-kinin system and Type I Interferons in Neurolupus

Uma Sriram, Viviana Zuluaga-Ramirez, Steven Franklin Merkel, Malika Winfield, Nicole C Fernandes, Sachin Gajghate, Stefania Gallucci, Yuri Persidsky
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 224.4.
https://doi.org/10.4049/jimmunol.198.Supp.224.4
Published: 01 May 2017
View article titled, Kallikrein-kinin system and Type I Interferons in Neurolupus
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Journal Articles

STAT2 Is Required for TLR-Induced Murine Dendritic Cell Activation and Cross-Presentation

Jun Xu, Michael H. Lee, Marita Chakhtoura, Benjamin L. Green, Kevin P. Kotredes, Robert W. Chain, Uma Sriram, Ana M. Gamero, Stefania Gallucci
Journal: The Journal of Immunology
J Immunol (2016) 197 (1): 326–336.
https://doi.org/10.4049/jimmunol.1500152
Published: 01 July 2016
View article titled, STAT2 Is Required for TLR-Induced Murine Dendritic Cell Activation and Cross-Presentation
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Includes: Supplementary data
Journal Articles

The effects of Estrogen on the IFN signature in Lupus

Michael Hweemoon Lee, Uma Sriram, Marita Chakhtoura, Robert W Chain, Roberto Caricchio, Stefania Gallucci
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 118.18.
https://doi.org/10.4049/jimmunol.196.Supp.118.18
Published: 01 May 2016
View article titled, The effects of Estrogen on the IFN signature in Lupus
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Journal Articles

Kallikrein-Kinin System suppresses Type I Interferon (IFN) responses: a novel mechanism of IFN regulation.

Uma Sriram, Nicole C. Fernandes, Michael Hweemoon Lee, Marta Didukh, Viviana Zuluaga-Ramirez, Raghava Potula, Stefania Gallucci
Journal: The Journal of Immunology
J Immunol (2016) 196 (1_Supplement): 210.3.
https://doi.org/10.4049/jimmunol.196.Supp.210.3
Published: 01 May 2016
View article titled, Kallikrein-Kinin System suppresses Type I Interferon (IFN) responses: a novel mechanism of IFN regulation.
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Journal Articles

Bacterial amyloids promote type I interferon production and accelerate autoimmunity (BA6P.124)

Stefania Gallucci, Paul Gallo, Glenn Rapsinski, Gertrude Oppong, Uma Sriram, Ronald Wilson, Bettina Buttaro, Cagla Tukel
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 114.5.
https://doi.org/10.4049/jimmunol.194.Supp.114.5
Published: 01 May 2015
View article titled, Bacterial amyloids promote type I interferon production and accelerate autoimmunity (BA6P.124)
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Journal Articles

Myeloid Dendritic Cells from B6.NZM Sle1/Sle2/Sle3 Lupus-Prone Mice Express an IFN Signature That Precedes Disease Onset

Uma Sriram, Linda Varghese, Heather L. Bennett, Neelakshi R. Jog, Debra K. Shivers, Yue Ning, Edward M. Behrens, Roberto Caricchio, Stefania Gallucci
Journal: The Journal of Immunology
J Immunol (2012) 189 (1): 80–91.
https://doi.org/10.4049/jimmunol.1101686
Published: 01 July 2012
View article titled, Myeloid Dendritic Cells from B6.NZM Sle1/Sle2/Sle3 Lupus-Prone Mice Express an IFN Signature That Precedes Disease Onset
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Includes: Supplementary data
Journal Articles

Type I IFN Signature in plasmacytoid dendritic cells from young Sle 1,2,3 lupus prone mice. (171.1)

Uma Sriram, Linda Varghese, Jun Xu, Stefania Gallucci
Journal: The Journal of Immunology
J Immunol (2012) 188 (1_Supplement): 171.1.
https://doi.org/10.4049/jimmunol.188.Supp.171.1
Published: 01 May 2012
View article titled, Type I IFN Signature in plasmacytoid dendritic cells from young Sle 1,2,3 lupus prone mice. (171.1)
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Journal Articles

The Actin Regulatory Protein HS1 Is Required for Antigen Uptake and Presentation by Dendritic Cells

Yanping Huang, Chhanda Biswas, Deborah A. Klos Dehring, Uma Sriram, Edward K. Williamson, Shuixing Li, Fiona Clarke, Stefania Gallucci, Yair Argon, Janis K. Burkhardt
Journal: The Journal of Immunology
J Immunol (2011) 187 (11): 5952–5963.
https://doi.org/10.4049/jimmunol.1100870
Published: 01 December 2011
View article titled, The Actin Regulatory Protein HS1 Is Required for Antigen Uptake and Presentation by Dendritic Cells
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Journal Articles

SOCS molecules are upregulated during IL-4-induced inhibition of Type I interferon responses in murine myeloid dendritic cells. (57.23)

Uma Sriram, Jun Xu, Linda Varghese, Heather Bennett, Debra Shivers, Stefania Gallucci
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 57.23.
https://doi.org/10.4049/jimmunol.186.Supp.57.23
Published: 01 April 2011
View article titled, SOCS molecules are upregulated during IL-4-induced inhibition of Type I interferon responses in murine myeloid dendritic cells. (57.23)
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Journal Articles

Intrinsic interferon signature in myeloid dendritic cells from lupus-prone mice precedes disease onset (47.1)

Stefania Gallucci, Linda Varghese, Heather Bennett, Neelakshi Jog, Debra Shivers, Yue Ning, Edward Behrens, Roberto Caricchio, Uma Sriram
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 47.1.
https://doi.org/10.4049/jimmunol.186.Supp.47.1
Published: 01 April 2011
View article titled, Intrinsic interferon signature in myeloid dendritic cells from lupus-prone mice precedes disease onset (47.1)
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Journal Articles

Intrinsic Interferon Signature in Dendritic Cells in lupus-prone mice. (83.9)

Stefania Gallucci, Heather Bennett, Debra Shivers, Yue Ning, Edward Behrens, Neelakshi Jog, Roberto Caricchio, Uma Sriram
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 83.9.
https://doi.org/10.4049/jimmunol.184.Supp.83.9
Published: 01 April 2010
View article titled, Intrinsic Interferon Signature in Dendritic Cells in lupus-prone mice. (83.9)
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Journal Articles

Kinetics and mechanisms of IL-4 suppression of Type I interferons’ responses in murine dendritic cells (134.22)

Uma Sriram, Heather Bennett, Jun Xu, Debra Shivers, Edward Behrens, Stefania Gallucci
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 134.22.
https://doi.org/10.4049/jimmunol.184.Supp.134.22
Published: 01 April 2010
View article titled, Kinetics and mechanisms of IL-4 suppression of Type I interferons’ responses in murine dendritic cells (134.22)
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Journal Articles

IL-4 Suppresses Dendritic Cell Response to Type I Interferons

Uma Sriram, Chhanda Biswas, Edward M. Behrens, Joudy-Ann Dinnall, Debra K. Shivers, Marc Monestier, Yair Argon, Stefania Gallucci
Journal: The Journal of Immunology
J Immunol (2007) 179 (10): 6446–6455.
https://doi.org/10.4049/jimmunol.179.10.6446
Published: 15 November 2007
View article titled, IL-4 Suppresses Dendritic Cell Response to Type I Interferons
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Journal Articles

Complement Receptor 3 Ligation of Dendritic Cells Suppresses Their Stimulatory Capacity

Edward M. Behrens, Uma Sriram, Debra K. Shivers, Marcello Gallucci, Zhengyu Ma, Terri H. Finkel, Stefania Gallucci
Journal: The Journal of Immunology
J Immunol (2007) 178 (10): 6268–6279.
https://doi.org/10.4049/jimmunol.178.10.6268
Published: 15 May 2007
View article titled, Complement Receptor 3 Ligation of Dendritic Cells Suppresses Their Stimulatory Capacity
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Journal Articles

Nuclear Autoantigen Translocation and Autoantibody Opsonization Lead to Increased Dendritic Cell Phagocytosis and Presentation of Nuclear Antigens: A Novel Pathogenic Pathway for Autoimmunity?

Lorenza Frisoni, Lenese Mcphie, Lucrezia Colonna, Uma Sriram, Marc Monestier, Stefania Gallucci, Roberto Caricchio
Journal: The Journal of Immunology
J Immunol (2005) 175 (4): 2692–2701.
https://doi.org/10.4049/jimmunol.175.4.2692
Published: 15 August 2005
View article titled, Nuclear Autoantigen Translocation and Autoantibody Opsonization Lead to Increased Dendritic Cell Phagocytosis and Presentation of Nuclear Antigens: A Novel Pathogenic Pathway for Autoimmunity?
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