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Vasileios C. Kyttaris
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Journal Articles

Downregulation of CD3ζ in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype

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Abel Suárez-Fueyo, Sean J. Bradley, Takayuki Katsuyama, Sarah Solomon, Eri Katsuyama, Vasileios C. Kyttaris, Vaishali R. Moulton, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2018) 200 (9): 3077–3086.
https://doi.org/10.4049/jimmunol.1700588
Published: 01 May 2018
View articletitled, Downregulation of CD3ζ in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype
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Includes: Supplementary data
Journal Articles

IL-23 Limits the Production of IL-2 and Promotes Autoimmunity in Lupus

Free
Hong Dai, Fan He, George C. Tsokos, Vasileios C. Kyttaris
Journal: The Journal of Immunology
J Immunol (2017) 199 (3): 903–910.
https://doi.org/10.4049/jimmunol.1700418
Published: 01 August 2017
View articletitled, IL-23 Limits the Production of IL-2 and Promotes Autoimmunity in Lupus
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Includes: Supplementary data
Journal Articles

CD74 Deficiency Mitigates Systemic Lupus Erythematosus–like Autoimmunity and Pathological Findings in Mice

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Yi Zhou, Huimei Chen, Li Liu, Xueqing Yu, Galina K. Sukhova, Min Yang, Lijun Zhang, Vasileios C. Kyttaris, George C. Tsokos, Isaac E. Stillman, Takaharu Ichimura, Joseph V. Bonventre, Peter Libby, Guo-Ping Shi
Journal: The Journal of Immunology
J Immunol (2017) 198 (7): 2568–2577.
https://doi.org/10.4049/jimmunol.1600028
Published: 01 April 2017
View articletitled, CD74 Deficiency Mitigates Systemic Lupus Erythematosus–like Autoimmunity and Pathological Findings in Mice
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Journal Articles

Cathepsin K Deficiency Ameliorates Systemic Lupus Erythematosus-like Manifestations in Faslpr Mice

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Yi Zhou, Huimei Chen, Li Liu, Xueqing Yu, Galina K. Sukhova, Min Yang, Vasileios C. Kyttaris, Isaac E. Stillman, Bruce Gelb, Peter Libby, George C. Tsokos, Guo-Ping Shi
Journal: The Journal of Immunology
J Immunol (2017) 198 (5): 1846–1854.
https://doi.org/10.4049/jimmunol.1501145
Published: 01 March 2017
View articletitled, Cathepsin K Deficiency Ameliorates Systemic Lupus Erythematosus-like Manifestations in Faslpr Mice
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Journal Articles

Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production

Free
Maria P. Karampetsou, Denis Comte, Katalin Kis-Toth, Cox Terhorst, Vasileios C. Kyttaris, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2016) 196 (12): 4915–4924.
https://doi.org/10.4049/jimmunol.1501523
Published: 15 June 2016
View articletitled, Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production
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Includes: Supplementary data
Journal Articles

Human Lupus Serum Induces Neutrophil-Mediated Organ Damage in Mice That Is Enabled by Mac-1 Deficiency

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Florencia Rosetti, Naotake Tsuboi, Kan Chen, Hiroshi Nishi, Thomas Ernandez, Sanjeev Sethi, Kevin Croce, George Stavrakis, Jorge Alcocer-Varela, Diana Gómez-Martin, Nico van Rooijen, Vasileios C. Kyttaris, Andrew H. Lichtman, George C. Tsokos, Tanya N. Mayadas
Journal: The Journal of Immunology
J Immunol (2012) 189 (7): 3714–3723.
https://doi.org/10.4049/jimmunol.1201594
Published: 01 October 2012
View articletitled, Human Lupus Serum Induces Neutrophil-Mediated Organ Damage in Mice That Is Enabled by Mac-1 Deficiency
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Includes: Supplementary data
Journal Articles

Increased Expression of SLAM Receptors SLAMF3 and SLAMF6 in Systemic Lupus Erythematosus T Lymphocytes Promotes Th17 Differentiation

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Madhumouli Chatterjee, Thomas Rauen, Katalin Kis-Toth, Vasileios C. Kyttaris, Christian M. Hedrich, Cox Terhorst, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2012) 188 (3): 1206–1212.
https://doi.org/10.4049/jimmunol.1102773
Published: 01 February 2012
View articletitled, Increased Expression of SLAM Receptors SLAMF3 and SLAMF6 in Systemic Lupus Erythematosus T Lymphocytes Promotes Th17 Differentiation
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Includes: Supplementary data
Journal Articles

Promoter Hypomethylation Results in Increased Expression of Protein Phosphatase 2A in T Cells from Patients with Systemic Lupus Erythematosus

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Katsue Sunahori, Yuang-Taung Juang, Vasileios C. Kyttaris, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2011) 186 (7): 4508–4517.
https://doi.org/10.4049/jimmunol.1000340
Published: 01 April 2011
View articletitled, Promoter Hypomethylation Results in Increased Expression of Protein Phosphatase 2A in T Cells from Patients with Systemic Lupus Erythematosus
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Journal Articles

Lupus Serum IgG Induces Skin Inflammation through the TNFR1 Signaling Pathway

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Guo-Min Deng, Lena Liu, Vasileios C. Kyttaris, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2010) 184 (12): 7154–7161.
https://doi.org/10.4049/jimmunol.0902514
Published: 15 June 2010
View articletitled, Lupus Serum IgG Induces Skin Inflammation through the TNFR1 Signaling Pathway
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Includes: Supplementary data
Journal Articles

Cutting Edge: IL-23 Receptor Deficiency Prevents the Development of Lupus Nephritis in C57BL/6–lpr/lpr Mice

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Vasileios C. Kyttaris, Zheng Zhang, Vijay K. Kuchroo, Mohamed Oukka, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2010) 184 (9): 4605–4609.
https://doi.org/10.4049/jimmunol.0903595
Published: 01 May 2010
View articletitled, Cutting Edge: IL-23 Receptor Deficiency Prevents the Development of Lupus Nephritis in C57BL/6–lpr/lpr Mice
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Includes: Supplementary data
Journal Articles

The Role of IL-23/IL-17 Axis in Lupus Nephritis

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Zheng Zhang, Vasileios C. Kyttaris, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2009) 183 (5): 3160–3169.
https://doi.org/10.4049/jimmunol.0900385
Published: 01 September 2009
View articletitled, The Role of IL-23/IL-17 Axis in Lupus Nephritis
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Journal Articles

Lupus serum induces skin inflammation through TNFR1 pathway (93.1)

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Guo-Min Deng, Lena Liu, Vasileios C Kyttaris, George C Tsokos
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 93.1.
https://doi.org/10.4049/jimmunol.182.Supp.93.1
Published: 01 April 2009
View articletitled, Lupus serum induces skin inflammation through TNFR1 pathway (93.1)
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Journal Articles

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

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José C. Crispín, Mohamed Oukka, George Bayliss, Robert A. Cohen, Christine A. Van Beek, Isaac E. Stillman, Vasileios C. Kyttaris, Yuang-Taung Juang, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2008) 181 (12): 8761–8766.
https://doi.org/10.4049/jimmunol.181.12.8761
Published: 15 December 2008
View articletitled, Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys
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Journal Articles

PP2A Dephosphorylates Elf-1 and Determines the Expression of CD3ζ and FcRγ in Human Systemic Lupus Erythematosus T Cells

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Yuang-Taung Juang, Ying Wang, Guisen Jiang, Hai-Bin Peng, Sukran Ergin, Michelle Finnell, Abigail Magilavy, Vasileios C. Kyttaris, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2008) 181 (5): 3658–3664.
https://doi.org/10.4049/jimmunol.181.5.3658
Published: 01 September 2008
View articletitled, PP2A Dephosphorylates Elf-1 and Determines the Expression of CD3ζ and FcRγ in Human Systemic Lupus Erythematosus T Cells
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Journal Articles

Elf-1 Binds to GGAA Elements on the FcRγ Promoter and Represses Its Expression

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Yuang-Taung Juang, Laarni Sumibcay, Mate Tolnay, Ying Wang, Vasileios C. Kyttaris, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2007) 179 (7): 4884–4889.
https://doi.org/10.4049/jimmunol.179.7.4884
Published: 01 October 2007
View articletitled, Elf-1 Binds to GGAA Elements on the FcRγ Promoter and Represses Its Expression
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Journal Articles

Increased Levels of NF-ATc2 Differentially Regulate CD154 and IL-2 Genes in T Cells from Patients with Systemic Lupus Erythematosus

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Vasileios C. Kyttaris, Ying Wang, Yuang-Taung Juang, Arthur Weinstein, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2007) 178 (3): 1960–1966.
https://doi.org/10.4049/jimmunol.178.3.1960
Published: 01 February 2007
View articletitled, Increased Levels of NF-ATc2 Differentially Regulate CD154 and IL-2 Genes in T Cells from Patients with Systemic Lupus Erythematosus
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Journal Articles

Phosphorylated ERM Is Responsible for Increased T Cell Polarization, Adhesion, and Migration in Patients with Systemic Lupus Erythematosus

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Yansong Li, Tatsuhiro Harada, Yuang-Taung Juang, Vasileios C. Kyttaris, Ying Wang, Michael Zidanic, Kenneth Tung, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2007) 178 (3): 1938–1947.
https://doi.org/10.4049/jimmunol.178.3.1938
Published: 01 February 2007
View articletitled, Phosphorylated ERM Is Responsible for Increased T Cell Polarization, Adhesion, and Migration in Patients with Systemic Lupus Erythematosus
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Journal Articles

The Cyclic AMP Response Element Modulator Regulates Transcription of the TCR ζ-Chain

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Klaus Tenbrock, Vasileios C. Kyttaris, Martina Ahlmann, Jan Mauno Ehrchen, Mate Tolnay, Harutyun Melkonyan, Christian Mawrin, Johannes Roth, Clemens Sorg, Yuang-Taung Juang, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2005) 175 (9): 5975–5980.
https://doi.org/10.4049/jimmunol.175.9.5975
Published: 01 November 2005
View articletitled, The Cyclic AMP Response Element Modulator Regulates Transcription of the TCR ζ-Chain
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Journal Articles

Increased Caspase-3 Expression and Activity Contribute to Reduced CD3ζ Expression in Systemic Lupus Erythematosus T Cells

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Sandeep Krishnan, Juliann G. Kiang, Carolyn U. Fisher, Madhusoodana P. Nambiar, Hang T. Nguyen, Vasileios C. Kyttaris, Bhabadeb Chowdhury, Violeta Rus, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2005) 175 (5): 3417–3423.
https://doi.org/10.4049/jimmunol.175.5.3417
Published: 01 September 2005
View articletitled, Increased Caspase-3 Expression and Activity Contribute to Reduced CD3ζ Expression in Systemic Lupus Erythematosus T Cells
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Journal Articles

Cyclic Adenosine 5′-Monophosphate Response Element Modulator Is Responsible for the Decreased Expression of c-fos and Activator Protein-1 Binding in T Cells from Patients with Systemic Lupus Erythematosus

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Vasileios C. Kyttaris, Yuang-Taung Juang, Klaus Tenbrock, Arthur Weinstein, George C. Tsokos
Journal: The Journal of Immunology
J Immunol (2004) 173 (5): 3557–3563.
https://doi.org/10.4049/jimmunol.173.5.3557
Published: 01 September 2004
View articletitled, Cyclic Adenosine 5′-Monophosphate Response Element Modulator Is Responsible for the Decreased Expression of c-fos and Activator Protein-1 Binding in T Cells from Patients with Systemic Lupus Erythematosus
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