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W M Kast
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Journal Articles

Targeting of cytotoxic T cells against leukemic B cells by bispecific antibody (aCD3 x aCD19) does not distract the T cell from its primary target.

S C Klein, S H van der Burg, L H Boer, C J Melief, W M Kast, G C de Gast, E J Bast
Journal: The Journal of Immunology
J Immunol (1997) 159 (11): 5545–5549.
https://doi.org/10.4049/jimmunol.159.11.5545
Published: 01 December 1997
View article titled, Targeting of cytotoxic T cells against leukemic B cells by bispecific antibody (aCD3 x aCD19) does not distract the T cell from its primary target.
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Journal Articles

HIV-1 reverse transcriptase-specific CTL against conserved epitopes do not protect against progression to AIDS.

S H van der Burg, M R Klein, O Pontesilli, A M Holwerda, J W Drijfhout, W M Kast, F Miedema, C J Melief
Journal: The Journal of Immunology
J Immunol (1997) 159 (7): 3648–3654.
https://doi.org/10.4049/jimmunol.159.7.3648
Published: 01 October 1997
View article titled, HIV-1 reverse transcriptase-specific CTL against conserved epitopes do not protect against progression to AIDS.
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Journal Articles

Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors.

R E Toes, R J Blom, R Offringa, W M Kast, C J Melief
Journal: The Journal of Immunology
J Immunol (1996) 156 (10): 3911–3918.
https://doi.org/10.4049/jimmunol.156.10.3911
Published: 15 May 1996
View article titled, Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors.
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Journal Articles

Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability.

S H van der Burg, M J Visseren, R M Brandt, W M Kast, C J Melief
Journal: The Journal of Immunology
J Immunol (1996) 156 (9): 3308–3314.
https://doi.org/10.4049/jimmunol.156.9.3308
Published: 01 May 1996
View article titled, Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability.
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Journal Articles

Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides.

M E Ressing, A Sette, R M Brandt, J Ruppert, P A Wentworth, M Hartman, C Oseroff, H M Grey, C J Melief, W M Kast
Journal: The Journal of Immunology
J Immunol (1995) 154 (11): 5934–5943.
https://doi.org/10.4049/jimmunol.154.11.5934
Published: 01 June 1995
View article titled, Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides.
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Journal Articles

MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells.

M J Kleijmeer, M A Ossevoort, C J van Veen, J J van Hellemond, J J Neefjes, W M Kast, C J Melief, H J Geuze
Journal: The Journal of Immunology
J Immunol (1995) 154 (11): 5715–5724.
https://doi.org/10.4049/jimmunol.154.11.5715
Published: 01 June 1995
View article titled, MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells.
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Journal Articles

CTL specific for the tyrosinase autoantigen can be induced from healthy donor blood to lyse melanoma cells.

M J Visseren, A van Elsas, E I van der Voort, M E Ressing, W M Kast, P I Schrier, C J Melief
Journal: The Journal of Immunology
J Immunol (1995) 154 (8): 3991–3998.
https://doi.org/10.4049/jimmunol.154.8.3991
Published: 15 April 1995
View article titled, CTL specific for the tyrosinase autoantigen can be induced from healthy donor blood to lyse melanoma cells.
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Journal Articles

An adenovirus type 5 early region 1B-encoded CTL epitope-mediating tumor eradication by CTL clones is down-modulated by an activated ras oncogene.

R E Toes, R Offringa, R J Blom, R M Brandt, A J van der Eb, C J Melief, W M Kast
Journal: The Journal of Immunology
J Immunol (1995) 154 (7): 3396–3405.
https://doi.org/10.4049/jimmunol.154.7.3396
Published: 01 April 1995
View article titled, An adenovirus type 5 early region 1B-encoded CTL epitope-mediating tumor eradication by CTL clones is down-modulated by an activated ras oncogene.
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Journal Articles

Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences.

A Neisig, J Roelse, A J Sijts, F Ossendorp, M C Feltkamp, W M Kast, C J Melief, J J Neefjes
Journal: The Journal of Immunology
J Immunol (1995) 154 (3): 1273–1279.
https://doi.org/10.4049/jimmunol.154.3.1273
Published: 01 February 1995
View article titled, Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences.
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Journal Articles

The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.

A Sette, A Vitiello, B Reherman, P Fowler, R Nayersina, W M Kast, C J Melief, C Oseroff, L Yuan, J Ruppert, J Sidney, M F del Guercio, S Southwood, R T Kubo, R W Chesnut, H M Grey, F V Chisari
Journal: The Journal of Immunology
J Immunol (1994) 153 (12): 5586–5592.
https://doi.org/10.4049/jimmunol.153.12.5586
Published: 15 December 1994
View article titled, The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes.
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Journal Articles

Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins.

W M Kast, R M Brandt, J Sidney, J W Drijfhout, R T Kubo, H M Grey, C J Melief, A Sette
Journal: The Journal of Immunology
J Immunol (1994) 152 (8): 3904–3912.
https://doi.org/10.4049/jimmunol.152.8.3904
Published: 15 April 1994
View article titled, Role of HLA-A motifs in identification of potential CTL epitopes in human papillomavirus type 16 E6 and E7 proteins.
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Journal Articles

Treatment with monoclonal anti-CD3 antibody protects against lethal Sendai virus infection by induction of natural killer cells.

W M Kast, J A Bluestone, M H Heemskerk, J Spaargaren, A C Voordouw, J D Ellenhorn, C J Melief
Journal: The Journal of Immunology
J Immunol (1990) 145 (7): 2254–2259.
https://doi.org/10.4049/jimmunol.145.7.2254
Published: 01 October 1990
View article titled, Treatment with monoclonal anti-CD3 antibody protects against lethal Sendai virus infection by induction of natural killer cells.
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Journal Articles

Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma (SCLC) by natural killer cells.

N J Stam, W M Kast, A C Voordouw, L B Pastoors, F A van der Hoeven, C J Melief, H L Ploegh
Journal: The Journal of Immunology
J Immunol (1989) 142 (11): 4113–4117.
https://doi.org/10.4049/jimmunol.142.11.4113
Published: 01 June 1989
View article titled, Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma (SCLC) by natural killer cells.
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Journal Articles

Failure or success in the restoration of virus-specific cytotoxic T lymphocyte response defects by dendritic cells.

W M Kast, C J Boog, B O Roep, A C Voordouw, C J Melief
Journal: The Journal of Immunology
J Immunol (1988) 140 (9): 3186–3193.
https://doi.org/10.4049/jimmunol.140.9.3186
Published: 01 May 1988
View article titled, Failure or success in the restoration of virus-specific cytotoxic T lymphocyte response defects by dendritic cells.
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Journal Articles

Regulation of the cytotoxic T lymphocyte response against Sendai virus analyzed with H-2 mutants.

L P de Waal, W M Kast, R W Melvold, C J Melief
Journal: The Journal of Immunology
J Immunol (1983) 130 (3): 1090–1096.
https://doi.org/10.4049/jimmunol.130.3.1090
Published: 01 March 1983
View article titled, Regulation of the cytotoxic T lymphocyte response against Sendai virus analyzed with H-2 mutants.
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