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Journal Articles

Inhibition of LRRK2 Kinase Activity in the Treatment of Crohn’s Disease

Sharmina Deloer, Ivan Fuss, Chalada Suebsuwong, Kunal Kumar, Robert J Devita, Inga Peter, Warren Strober
Journal: The Journal of Immunology
J Immunol (2022) 208 (1_Supplement): 163.06.
DOI: https://doi.org/10.4049/jimmunol.208.Supp.163.06
Published: 01 May 2022
View article titled, Inhibition of LRRK2 Kinase Activity in the Treatment of Crohn’s Disease
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Autoinflammatory Eye Disease Due to NLRP3 Inflammasome-Associated Mutations and Excessive IL-1β Responses may be Driven by Ocular Exposure to Commensals

Jay Siak, Anthony J St. Leger, Mary Mattapallil, M. Teresa Magone, Wadih Zein, Sara Alehashemi, Kumarkrishna Raychaudhuri, Guangxun Meng, Ivan Fuss, Warren Strober, Raphaela Goldbach-Mansky, Rachel R Caspi
Journal: The Journal of Immunology
J Immunol (2020) 204 (1_Supplement): 224.41.
DOI: https://doi.org/10.4049/jimmunol.204.Supp.224.41
Published: 01 May 2020
View article titled, Autoinflammatory Eye Disease Due to NLRP3 Inflammasome-Associated Mutations and Excessive IL-1β Responses may be Driven by Ocular Exposure to Commensals
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Journal Articles

Commensal microbiota as possible pathobiont in autoinflammatory disease

Jay Siak, Anthony St. Leger, Kumarkrishna Raychaudhuri, Mary Mattapallil, Ivan J Fuss, Raphaela Goldbach-Mansky, Warren Strober, Rachel R Caspi
Journal: The Journal of Immunology
J Immunol (2019) 202 (1_Supplement): 120.26.
DOI: https://doi.org/10.4049/jimmunol.202.Supp.120.26
Published: 01 May 2019
View article titled, Commensal microbiota as possible pathobiont in autoinflammatory disease
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Chronic Fibro-Inflammatory Responses in Autoimmune Pancreatitis Depend on IFN-α and IL-33 Produced by Plasmacytoid Dendritic Cells

Tomohiro Watanabe, Kouhei Yamashita, Yasuyuki Arai, Kosuke Minaga, Ken Kamata, Tomoyuki Nagai, Yoriaki Komeda, Mamoru Takenaka, Satoru Hagiwara, Hiroshi Ida, Toshiharu Sakurai, Naoshi Nishida, Warren Strober, Masatoshi Kudo
Journal: The Journal of Immunology
J Immunol (2017) 198 (10): 3886–3896.
DOI: https://doi.org/10.4049/jimmunol.1700060
Published: 15 May 2017
View article titled, Chronic Fibro-Inflammatory Responses in Autoimmune Pancreatitis Depend on IFN-α and IL-33 Produced by Plasmacytoid Dendritic Cells
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Includes: Supplementary data
Journal Articles

An aberrant immune response to an ocular commensal results in disease in a mouse model of Muckle-Wells Syndrome

Kumarkrishna Raychaudhuri, Anthony St Leger, Fatimah Almaghrabi, Ivan J. Fuss, Warren Strober, Rachel R Caspi
Journal: The Journal of Immunology
J Immunol (2017) 198 (1_Supplement): 55.43.
DOI: https://doi.org/10.4049/jimmunol.198.Supp.55.43
Published: 01 May 2017
View article titled, An aberrant immune response to an ocular commensal results in disease in a mouse model of Muckle-Wells Syndrome
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Journal Articles

The Inflammatory Bowel Disease–Associated Autophagy Gene Atg16L1T300A Acts as a Dominant Negative Variant in Mice

Ping Gao, Hongtao Liu, Huarong Huang, Qi Zhang, Warren Strober, Fuping Zhang
Journal: The Journal of Immunology
J Immunol (2017) 198 (6): 2457–2467.
DOI: https://doi.org/10.4049/jimmunol.1502652
Published: 15 March 2017
View article titled, The Inflammatory Bowel Disease–Associated Autophagy Gene Atg16L1T300A Acts as a Dominant Negative Variant in Mice
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Journal Articles

Plasmacytoid Dendritic Cell Activation and IFN-α Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis

Yasuyuki Arai, Kouhei Yamashita, Katsutoshi Kuriyama, Masahiro Shiokawa, Yuzo Kodama, Toshiharu Sakurai, Kiyomi Mizugishi, Kazushige Uchida, Norimitsu Kadowaki, Akifumi Takaori-Kondo, Masatoshi Kudo, Kazuichi Okazaki, Warren Strober, Tsutomu Chiba, Tomohiro Watanabe
Journal: The Journal of Immunology
J Immunol (2015) 195 (7): 3033–3044.
DOI: https://doi.org/10.4049/jimmunol.1500971
Published: 01 October 2015
View article titled, Plasmacytoid Dendritic Cell Activation and IFN-α Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis
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Includes: Supplementary data
Journal Articles

Fungal recognition by Dectin-1 on dendritic cells induces IL-10 producing CD4+ T cells by GATA3 / C/EBP-β pathway (MPF4P.733)

Masaki Tajima, Ivan Fuss, Atsushi Kitani, Warren Strober
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 136.9.
DOI: https://doi.org/10.4049/jimmunol.194.Supp.136.9
Published: 01 May 2015
View article titled, Fungal recognition by Dectin-1 on dendritic cells induces IL-10 producing CD4<sup>+</sup> T cells by GATA3 / C/EBP-β pathway (MPF4P.733)
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Journal Articles

IL-13 Orchestrates Resolution of Chronic Intestinal Inflammation via Phosphorylation of Glycogen Synthase Kinase-3β

Stefan Fichtner-Feigl, Rebecca Kesselring, Maria Martin, Florian Obermeier, Petra Ruemmele, Atsushi Kitani, Stefan M. Brunner, Michael Haimerl, Edward K. Geissler, Warren Strober, Hans J. Schlitt
Journal: The Journal of Immunology
J Immunol (2014) 192 (8): 3969–3980.
DOI: https://doi.org/10.4049/jimmunol.1301072
Published: 15 April 2014
View article titled, IL-13 Orchestrates Resolution of Chronic Intestinal Inflammation via Phosphorylation of Glycogen Synthase Kinase-3β
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Includes: Supplementary data
Journal Articles

A Polymorphism in the Coding Region of Il12b Promotes IL-12p70 and IL-23 Heterodimer Formation

Antonie Zwiers, Ivan J. Fuss, Diana Seegers, Tanja Konijn, Juan J. Garcia-Vallejo, Janneke N. Samsom, Warren Strober, Georg Kraal, Gerd Bouma
Journal: The Journal of Immunology
J Immunol (2011) 186 (6): 3572–3580.
DOI: https://doi.org/10.4049/jimmunol.1001330
Published: 15 March 2011
View article titled, A Polymorphism in the Coding Region of Il12b Promotes IL-12p70 and IL-23 Heterodimer Formation
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Includes: Supplementary data
Journal Articles

The role of TL1A-DR3 TNF-family interactions in inflammatory bowel disease (39.3)

Françoise Meylan, Yun-Jeong Song, Ian Malm, Krishika Acharya, Erin Kahle, Ivan Fuss, Warren Strober, Yasmine Belkaid, Richard Siegel
Journal: The Journal of Immunology
J Immunol (2009) 182 (1_Supplement): 39.3.
DOI: https://doi.org/10.4049/jimmunol.182.Supp.39.3
Published: 01 April 2009
View article titled, The role of TL1A-DR3 TNF-family interactions in inflammatory bowel disease (39.3)
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Journal Articles

Notch1 Signaling and Regulatory T Cell Function

Naoki Asano, Tomohiro Watanabe, Atsushi Kitani, Ivan J. Fuss, Warren Strober
Journal: The Journal of Immunology
J Immunol (2008) 180 (5): 2796–2804.
DOI: https://doi.org/10.4049/jimmunol.180.5.2796
Published: 01 March 2008
View article titled, Notch1 Signaling and Regulatory T Cell Function
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Journal Articles

Cutting Edge: Regulatory T Cells Induce CD4+CD25−Foxp3− T Cells or Are Self-Induced to Become Th17 Cells in the Absence of Exogenous TGF-β

LiLi Xu, Atsushi Kitani, Ivan Fuss, Warren Strober
Journal: The Journal of Immunology
J Immunol (2007) 178 (11): 6725–6729.
DOI: https://doi.org/10.4049/jimmunol.178.11.6725
Published: 01 June 2007
View article titled, Cutting Edge: Regulatory T Cells Induce CD4<sup>+</sup>CD25<sup>−</sup>Foxp3<sup>−</sup> T Cells or Are Self-Induced to Become Th17 Cells in the Absence of Exogenous TGF-β
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Journal Articles

Induction of IL-13 Triggers TGF-β1-Dependent Tissue Fibrosis in Chronic 2,4,6-Trinitrobenzene Sulfonic Acid Colitis

Stefan Fichtner-Feigl, Ivan J. Fuss, Cheryl A. Young, Tomohiro Watanabe, Edward K. Geissler, Hans-Jürgen Schlitt, Atsushi Kitani, Warren Strober
Journal: The Journal of Immunology
J Immunol (2007) 178 (9): 5859–5870.
DOI: https://doi.org/10.4049/jimmunol.178.9.5859
Published: 01 May 2007
View article titled, Induction of IL-13 Triggers TGF-β<sub>1</sub>-Dependent Tissue Fibrosis in Chronic 2,4,6-Trinitrobenzene Sulfonic Acid Colitis
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Journal Articles

Antibodies to Complement Receptor 3 Treat Established Inflammation in Murine Models of Colitis and a Novel Model of Psoriasiform Dermatitis

Francisco Leon, Nikhat Contractor, Ivan Fuss, Thomas Marth, Edward Lahey, Shoko Iwaki, Andrea la Sala, Victoria Hoffmann, Warren Strober, Brian L. Kelsall
Journal: The Journal of Immunology
J Immunol (2006) 177 (10): 6974–6982.
DOI: https://doi.org/10.4049/jimmunol.177.10.6974
Published: 15 November 2006
View article titled, Antibodies to Complement Receptor 3 Treat Established Inflammation in Murine Models of Colitis and a Novel Model of Psoriasiform Dermatitis
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Journal Articles

TGF-β-Mediated Suppression by CD4+CD25+ T Cells Is Facilitated by CTLA-4 Signaling

Takatoku Oida, LiLi Xu, Howard L. Weiner, Atsushi Kitani, Warren Strober
Journal: The Journal of Immunology
J Immunol (2006) 177 (4): 2331–2339.
DOI: https://doi.org/10.4049/jimmunol.177.4.2331
Published: 15 August 2006
View article titled, TGF-β-Mediated Suppression by CD4<sup>+</sup>CD25<sup>+</sup> T Cells Is Facilitated by CTLA-4 Signaling
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Journal Articles

Probiotics Ameliorate Recurrent Th1-Mediated Murine Colitis by Inducing IL-10 and IL-10-Dependent TGF-β-Bearing Regulatory Cells

Claudia Di Giacinto, Mariarosaria Marinaro, Massimo Sanchez, Warren Strober, Monica Boirivant
Journal: The Journal of Immunology
J Immunol (2005) 174 (6): 3237–3246.
DOI: https://doi.org/10.4049/jimmunol.174.6.3237
Published: 15 March 2005
View article titled, Probiotics Ameliorate Recurrent Th1-Mediated Murine Colitis by Inducing IL-10 and IL-10-Dependent TGF-β-Bearing Regulatory Cells
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TGF-β1 Plays an Important Role in the Mechanism of CD4+CD25+ Regulatory T Cell Activity in Both Humans and Mice

Kazuhiko Nakamura, Atsushi Kitani, Ivan Fuss, Aasta Pedersen, Naohiko Harada, Hajime Nawata, Warren Strober
Journal: The Journal of Immunology
J Immunol (2004) 172 (2): 834–842.
DOI: https://doi.org/10.4049/jimmunol.172.2.834
Published: 15 January 2004
View article titled, TGF-β1 Plays an Important Role in the Mechanism of CD4<sup>+</sup>CD25<sup>+</sup> Regulatory T Cell Activity in Both Humans and Mice
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Activated STAT4 Has an Essential Role in Th1 Differentiation and Proliferation That Is Independent of Its Role in the Maintenance of IL-12Rβ2 Chain Expression and Signaling

Ryuta Nishikomori, Takashi Usui, Chang-Yu Wu, Akio Morinobu, John J. O’Shea, Warren Strober
Journal: The Journal of Immunology
J Immunol (2002) 169 (8): 4388–4398.
DOI: https://doi.org/10.4049/jimmunol.169.8.4388
Published: 15 October 2002
View article titled, Activated STAT4 Has an Essential Role in Th1 Differentiation and Proliferation That Is Independent of Its Role in the Maintenance of IL-12Rβ2 Chain Expression and Signaling
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The Interrelated Roles of TGF-β and IL-10 in the Regulation of Experimental Colitis

Ivan J. Fuss, Monica Boirivant, Brian Lacy, Warren Strober
Journal: The Journal of Immunology
J Immunol (2002) 168 (2): 900–908.
DOI: https://doi.org/10.4049/jimmunol.168.2.900
Published: 15 January 2002
View article titled, The Interrelated Roles of TGF-β and IL-10 in the Regulation of Experimental Colitis
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