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Weiguo Zhang
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Journal Articles

Phospholipase D in TCR-Mediated Signaling and T Cell Activation

Minghua Zhu, Daniel P. Foreman, Sarah A. O’Brien, Yuefei Jin, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2018) 200 (6): 2165–2173.
https://doi.org/10.4049/jimmunol.1701291
Published: 15 March 2018
View article titled, Phospholipase D in TCR-Mediated Signaling and T Cell Activation
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Journal Articles

Differential Requirements of TCR Signaling in Homeostatic Maintenance and Function of Dendritic Epidermal T Cells

Baojun Zhang, Jianxuan Wu, Yiqun Jiao, Cheryl Bock, Meifang Dai, Benny Chen, Nelson Chao, Weiguo Zhang, Yuan Zhuang
Journal: The Journal of Immunology
J Immunol (2015) 195 (9): 4282–4291.
https://doi.org/10.4049/jimmunol.1501220
Published: 01 November 2015
View article titled, Differential Requirements of TCR Signaling in Homeostatic Maintenance and Function of Dendritic Epidermal T Cells
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Includes: Multimedia, Supplementary data
Journal Articles

Differential Roles of Phospholipase D Proteins in FcεRI-Mediated Signaling and Mast Cell Function

Minghua Zhu, Jianwei Zou, Tieshi Li, Sarah A. O’Brien, Yao Zhang, Sarah Ogden, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2015) 195 (9): 4492–4502.
https://doi.org/10.4049/jimmunol.1500665
Published: 01 November 2015
View article titled, Differential Roles of Phospholipase D Proteins in FcεRI-Mediated Signaling and Mast Cell Function
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Journal Articles

The Importance of IL-6 in the Development of LAT-Mediated Autoimmunity

Sarah A. O’Brien, Minghua Zhu, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2015) 195 (2): 695–705.
https://doi.org/10.4049/jimmunol.1403187
Published: 15 July 2015
View article titled, The Importance of IL-6 in the Development of LAT-Mediated Autoimmunity
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Journal Articles

LAT-mediated TCR signaling is required for optimal function and clonal expansion but not long-term survival and homeostatic turnover of DETCs (LYM7P.610)

Baojun Zhang, CHERYL BOCK, Jianxuan Wu, Yiqun Jiao, Benny Chen, Nelson Chao, Weiguo Zhang, Yuan Zhuang
Journal: The Journal of Immunology
J Immunol (2015) 194 (1_Supplement): 200.2.
https://doi.org/10.4049/jimmunol.194.Supp.200.2
Published: 01 May 2015
View article titled, LAT-mediated TCR signaling is required for optimal function and clonal expansion but not long-term survival and homeostatic turnover of DETCs (LYM7P.610)
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Journal Articles

Linker for activation of T cells (LAT) in the regulation of T cell activation and autoimmunity (BA2P.121)

Weiguo Zhang, Sarah Sullivan, Minghua Zhu, Catherine Lewis
Journal: The Journal of Immunology
J Immunol (2014) 192 (1_Supplement): 45.8.
https://doi.org/10.4049/jimmunol.192.Supp.45.8
Published: 01 May 2014
View article titled, Linker for activation of T cells (LAT) in the regulation of T cell activation and autoimmunity (BA2P.121)
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Journal Articles

The Role of LAT–PLCγ1 Interaction in γδ T Cell Development and Homeostasis

Sarah A. Sullivan, Minghua Zhu, Steven Bao, Catherine A. Lewis, Chih-wen Ou-Yang, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2014) 192 (6): 2865–2874.
https://doi.org/10.4049/jimmunol.1302493
Published: 15 March 2014
View article titled, The Role of LAT–PLCγ1 Interaction in γδ T Cell Development and Homeostasis
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Includes: Supplementary data
Journal Articles

Characterization of the cytokine and transcription factor profile of CD4+ T cells from conditional LATY136F mice (P4133)

Greg Swan, Sarah Sullivan, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2013) 190 (1_Supplement): 133.20.
https://doi.org/10.4049/jimmunol.190.Supp.133.20
Published: 01 May 2013
View article titled, Characterization of the cytokine and transcription factor profile of CD4+ T cells from conditional LATY136F mice (P4133)
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Journal Articles

The Requirement of Linker for Activation of T Cells in the Primary and Memory Responses of CD8 T Cells

Chih-wen Ou-Yang, Minghua Zhu, Sarah A. Sullivan, Deirdre M. Fuller, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2013) 190 (6): 2938–2947.
https://doi.org/10.4049/jimmunol.1203163
Published: 15 March 2013
View article titled, The Requirement of Linker for Activation of T Cells in the Primary and Memory Responses of CD8 T Cells
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Journal Articles

The Importance of the Erk Pathway in the Development of Linker for Activation of T Cells-Mediated Autoimmunity

Deirdre M. Fuller, Minghua Zhu, Surapong Koonpaew, Mariana I. Nelson, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2012) 189 (8): 4005–4013.
https://doi.org/10.4049/jimmunol.1201380
Published: 15 October 2012
View article titled, The Importance of the Erk Pathway in the Development of Linker for Activation of T Cells-Mediated Autoimmunity
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Journal Articles

Differential Requirement of RasGRP1 for γδ T Cell Development and Activation

Yong Chen, Xinxin Ci, Balachandra Gorentla, Sarah A. Sullivan, James C. Stone, Weiguo Zhang, Pablo Pereira, Jianxin Lu, Xiao-Ping Zhong
Journal: The Journal of Immunology
J Immunol (2012) 189 (1): 61–71.
https://doi.org/10.4049/jimmunol.1103272
Published: 01 July 2012
View article titled, Differential Requirement of RasGRP1 for γδ T Cell Development and Activation
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Journal Articles

Tyrosine Phosphorylation-Independent Regulation of Lipopolysaccharide-Mediated Response by the Transmembrane Adaptor Protein LAB

Minghua Zhu, Deirdre M. Fuller, Chih-wen Ou-Yang, Sarah A. Sullivan, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2012) 188 (6): 2733–2741.
https://doi.org/10.4049/jimmunol.1101581
Published: 15 March 2012
View article titled, Tyrosine Phosphorylation-Independent Regulation of Lipopolysaccharide-Mediated Response by the Transmembrane Adaptor Protein LAB
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Journal Articles

Regulation of Erk activation in T cells through the tail domain of RasGRP1 (160.5)

Deirdre Fuller, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 160.5.
https://doi.org/10.4049/jimmunol.186.Supp.160.5
Published: 01 April 2011
View article titled, Regulation of Erk activation in T cells through the tail domain of RasGRP1 (160.5)
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Journal Articles

LAT-independent triggering of granule-mediated cytotoxicity of CD8 T cells (109.32)

Chihwen (Claudia) Ouyang, Minghua Zhu, Qi-jing Li, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2011) 186 (1_Supplement): 109.32.
https://doi.org/10.4049/jimmunol.186.Supp.109.32
Published: 01 April 2011
View article titled, LAT-independent triggering of granule-mediated cytotoxicity of CD8 T cells (109.32)
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Journal Articles

LAB/NTAL regulates zymosan-mediated inflammatory responses in Bone Marrow Derived Dendritic Cells (BMDC) (98.14)

Selinda Orr, Laura Quigley, Stephen Roessler, Deborah Hodge, Catherine Razzook, Marco Cardone, Weiguo Zhang, Giorgio Trinchieri, Lyudmila Lyakh, Daniel McVicar
Journal: The Journal of Immunology
J Immunol (2010) 184 (1_Supplement): 98.14.
https://doi.org/10.4049/jimmunol.184.Supp.98.14
Published: 01 April 2010
View article titled, LAB/NTAL regulates zymosan-mediated inflammatory responses in Bone Marrow Derived Dendritic Cells (BMDC) (98.14)
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Journal Articles

The Role of the LAT–PLC-γ1 Interaction in T Regulatory Cell Function

Mariana I. Chuck, Minghua Zhu, Shudan Shen, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2010) 184 (5): 2476–2486.
https://doi.org/10.4049/jimmunol.0902876
Published: 01 March 2010
View article titled, The Role of the LAT–PLC-γ1 Interaction in T Regulatory Cell Function
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Journal Articles

Palmitoylation-Dependent Plasma Membrane Transport but Lipid Raft-Independent Signaling by Linker for Activation of T Cells

Matthias Hundt, Yohsuke Harada, Lauren De Giorgio, Natsuko Tanimura, Weiguo Zhang, Amnon Altman
Journal: The Journal of Immunology
J Immunol (2009) 183 (3): 1685–1694.
https://doi.org/10.4049/jimmunol.0803921
Published: 01 August 2009
View article titled, Palmitoylation-Dependent Plasma Membrane Transport but Lipid Raft-Independent Signaling by Linker for Activation of T Cells
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Journal Articles

The Essential Role of LAT in Thymocyte Development during Transition from the Double-Positive to Single-Positive Stage

Shudan Shen, Minghua Zhu, Jasmine Lau, Mariana Chuck, Weiguo Zhang
Journal: The Journal of Immunology
J Immunol (2009) 182 (9): 5596–5604.
https://doi.org/10.4049/jimmunol.0803170
Published: 01 May 2009
View article titled, The Essential Role of LAT in Thymocyte Development during Transition from the Double-Positive to Single-Positive Stage
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Journal Articles

Negative Regulation of TCR Signaling by Linker for Activation of X Cells via Phosphotyrosine-Dependent and -Independent Mechanisms

Michael J. Shapiro, Chau T. Nguyen, Haig Aghajanian, Weiguo Zhang, Virginia Smith Shapiro
Journal: The Journal of Immunology
J Immunol (2008) 181 (10): 7055–7061.
https://doi.org/10.4049/jimmunol.181.10.7055
Published: 15 November 2008
View article titled, Negative Regulation of TCR Signaling by Linker for Activation of X Cells via Phosphotyrosine-Dependent and -Independent Mechanisms
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Journal Articles

Mouse TCRαβ+CD8αα Intraepithelial Lymphocytes Express Genes That Down-Regulate Their Antigen Reactivity and Suppress Immune Responses

Timothy L. Denning, Steve Granger, Daniel Mucida, Ryan Graddy, Georges Leclercq, Weiguo Zhang, Karen Honey, Jeffrey P. Rasmussen, Hilde Cheroutre, Alexander Y. Rudensky, Mitchell Kronenberg
Journal: The Journal of Immunology
J Immunol (2007) 178 (7): 4230–4239.
https://doi.org/10.4049/jimmunol.178.7.4230
Published: 01 April 2007
View article titled, Mouse TCRαβ<sup>+</sup>CD8αα Intraepithelial Lymphocytes Express Genes That Down-Regulate Their Antigen Reactivity and Suppress Immune Responses
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